Use of Gastroprotective Drugs in Patients Receiving Low-dose Aspirin

Journal of the Chinese Medical Association

Volumn 72, Issue 7, 2009, Pages 356-361

  Luk, Ho Hoi ^a  

^a TUNG WAH HOSPITAL   (Hong Kong)

Author keywords

anti ulcer agents; aspirin; drug utilization

Indexed keywords

ACETYLSALICYLIC ACID; ANTACID AGENT; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; DIGESTIVE SYSTEM ULCER; FEMALE; GASTROINTESTINAL DISEASE; GASTROINTESTINAL HEMORRHAGE; HUMAN; INFORMATION PROCESSING; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MEDICAL SPECIALIST; OUTPATIENT DEPARTMENT; PRESCRIPTION; RETROSPECTIVE STUDY; STOMACH PROTECTION;

ADULT; AGED; AGED, 80 AND OVER; ANTACIDS; ASPIRIN; FEMALE; GASTROINTESTINAL HEMORRHAGE; HISTAMINE H2 ANTAGONISTS; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PEPTIC ULCER; RETROSPECTIVE STUDIES;

EID: 70149087096     PISSN: 17264901     EISSN: 17287731     Source Type: Journal    
DOI: 10.1016/S1726-4901(09)70387-9     Document Type: Article

References (37)

1. Wood D.M., Plehwet W.E., and Colmant P.G. Aspirin usage in a large teaching hospital diabetes clinic setting. Diabet Med 16 (1999) 605-608
2. Albers G.W., and Tijssen J.G. Antiplatelet therapy: new foundations for optimal treatment decisions. Neurology 53 (1999) S25-S31
3. Weisman S.M., and Graham D.Y. Evaluation of the benefits and risks of low-dose aspirin in the secondary prevention of cardiovascular and cerebrovascular events. Arch Intern Med 162 (2002) 2197-2202
4. Pearson T.A., Blair S.N., Daniels S.R., Eckel R.H., Fair J.M., Fortmann S.P., Franklinet B.A., et al. AHA guidelines for primary prevention of cardiovascular disease and stroke, 2002 update. Consensus panel guide to comprehensive risk reduction for adult patients without coronary or other atherosclerotic vascular diseases. American Heart Association Science Advisory and Coordinating Committee. Circulation 106 (2002) 388-391
5. Derry S., and Loke Y.K. Risk of gastrointestinal haemorrhage with long term use of aspirin: meta-analysis. BMJ 321 (2000) 1183-1187
6. Luk H.H., Pang J., Li L.S.W., and Ng M. Use of antiplatelet drugs in the stroke unit of a Hong Kong hospital. Pharm World Sci 27 (2005) 258-262
7. See Y., Ng S.C., Tho K.S., and Teo S.K. Are antacids necessary as routine prescriptives with non-steroidal anti-inflammatory drugs?. Ann Acad Med Singap 27 (1998) 219-222
8. Lim K.H., and Yap K.B. The prescribing pattern of outpatient polyclinic doctors. Singapore Med J 40 (1999) 416-419
9. Yap K.B., and Chan K.M. The prescribing pattern of hospital doctors. Singapore Med J 39 (1998) 496-500
10. Chan F.K.L. Management of high-risk patient on nonsteroidal anti-inflammatory drugs or aspirin. Drugs 66 Suppl (2006) 23-28
11. Wolfe M.M., Lichtenstein D.R., and Singh G. Gastrointestinal toxicity of nonsteroidal antiinflammatory drugs. N Engl J Med 340 (1999) 1888-1899
12. Vane J.R., and Botting R.M. Mechanism of action of nonsteroidal anti-inflammatory drugs. Am J Med 104 (1998) 25-85
13. Chan F.K.L., and Leung W.K. Peptic-ulcer disease. Lancet 360 (2002) 933-940
14. National Institute for Clinical Excellence. Guidance on the use of cyclooxygenase (COX) II selective inhibitors celecoxib, rofecoxib, meloxicam and todolac for osteoarthritis and rheumatoid arthritis. Technology Appraisal Guidance No. 27. Available at http://guidance.nice.org.uk/TA27/guidance/pdf/English [Date accessed: December 1, 2007]
15. Targownik L.E., and Al-Mamfud A. The prevalence of risk factors for gastrointestinal complications and use of gastroprotection among persons hospitalized for cardiovascular disease. Aliment Pharmacol Ther 23 (2006) 743-749
16. American College of Rheumatology. Guidelines for the management of rheumatoid arthritis: 2002 update. Arthritis Rheum 46 (2002) 328-346
17. van Dijk K.N., ter Huurne K., de Vries C.S., van den Berg P.B., Brouwers J.R., and de Jong-van den Berg L.T. Prescribing of gastroprotective drugs among elderly NSAID users in The Netherlands. Pharm World Sci 24 (2002) 100-103
18. Abraham N.S., El-Serag H.B., Johnson M.L., Hartman C., Richardson P., Ray W.A., and Smalley W. National adherence to evidence-based guidelines for the prescription of nonsteroidal anti-inflammatory drugs. Gastroenterology 129 (2005) 1171-1178
19. Harris C.L., Raisch D.W., Abhyankar U., Marfatia S., Campbell H.M., and Sather M.R. GI risk factors and use of protective agents among patients receiving nonsteroidal antiinflammatory drugs. Ann Pharmacother 40 (2006) 1924-1931
20. Hogan D.B., Campbell N.R., Crutcher R., Jennett P., and MacLeod N. Prescription of nonsteroidal anti-inflammatory drugs for elderly people in Alberta. CMAJ 151 (1994) 315-322
21. Clinard F., Bardou M., Sgro C., Lefevre N., Raphael F., Paille F., Dumas M., et al. Non-steroidal anti-inflammatory and cytoprotective drug co-prescription in general practice: a general practitioner-based survey in France. Eur J Clin Pharmacol 57 (2001) 737-743
22. Caputi A.P., Kong S.X., Mavros P., Ricci E., and Russo A. Concomitant use of gastroprotective agents among users of nonsteroidal antiinflammatory drugs in Italy. Ann Rheum Dis 60 Suppl (2001) 275
23. Cryer B., and Feldman M. Effects of very low dose daily, long-term aspirin therapy on gastric, duodenal, and rectal prostaglandin levels and on mucosal injury in healthy humans. Gastroenterology 117 (1999) 17-25
24. McQuaid K.R., and Laine L. Systematic review and meta-analysis of adverse events of low-dose aspirin and clopidogrel in randomized controlled trials. Am J Med 119 (2006) 624-638
25. Sorensen H.T., Mellemkjaer L., Blot W.J., Nielsen G.L., Steffensen F.H., McLaughlin J.K., and Olsen J.H. Risk of upper gastrointestinal bleeding associated with use of low-dose aspirin. Am J Gastroenterol 95 (2000) 2218-2224
26. Chey W.D., Eswaren S., Howden C.W., Inadomi J.M., Fendrick A.M., and Scheiman J.M. Primary care physician perceptions of nonsteroidal anti-inflammatory drug and aspirin-associated toxicity: results of a national survey. Aliment Pharmacol Ther 23 (2006) 655-668
27. Kelly J.P., Kaufman D.W., Jurgelon J.M., Sheehan J., Koff R.S., and Shapiro S. Risk of aspirin-associated major upper-gastrointestinal bleeding with enteric-coated or buffered product. Lancet 348 (1996) 1413-1416
28. Ibanez L., Vidal X., Vendrell L., Moretti U., and Laporte J.R. Upper gastrointestinal bleeding associated with antiplatelet drugs. Aliment Pharmacol Ther 23 (2006) 235-242
29. Lai K.C., Lam S.K., Chu K.M., Wong B.C., Hui W.M., Hu W.H., Lau K.K., et al. Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med 346 (2002) 2033-2038
30. Chan F.K., Ching J.Y., Hung L.C., Wong V.W., Leung V.K., Kung N.N., Hui A.J., et al. Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding. N Engl J Med 352 (2005) 238-244
31. Erdeljic V., Francetic I., Sarinic V.M., Bilusic M., Auaperger K.M., Huic M., and Mercep I. Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study. Pharm World Sci 28 (2006) 318-325
32. Silverstein F.E., Graham D.Y., Senior J.R., Davies H.W., Struthers B.J., Bittman R.M., and Geis G.S. Misoprostol reduces serious gastrointestinal complications in patients with rheumatoid arthritis receiving nonsteroidal anti-inflammatory drugs: a randomized, double-blind, placebo-controlled trial. Ann Intern Med 123 (1995) 241-249
33. Ong C.K.S., Lirk P., Tan C.H., and Seymour R.A. An evidence-based update on nonsteroidal anti-inflammatory drugs. Clin Med Res 5 (2007) 19-34
34. Micklewright R., Lane S., Linley W., McQuade C., Thompson F., and Maskrey N. NSAIDs, gastroprotection and cyclo-oxygenase-II-selective inhibitors. Aliment Pharmacol Ther 17 (2003) 321-332
35. Singh G., Ramey D.R., Morfeld D., Shi H., Hatoum H.T., and Fries J.F. Gastrointestinal tract complications of nonsteroidal anti-inflammatory drug treatment in rheumatoid arthritis: a prospective observational cohort study. Arch Intern Med 156 (1996) 1530-1536
36. Lazzaroni M., Sainaghi M., and Bianchi P.G. Non-steroidal antiinflammatory drug gastropathy: clinical results with antacids and sucralfate. Ital J Gastroenterol Hepatol 31 (1999) S48-S53
37. Lanas A., and Ferrandez A. Inappropriate prevention of NSAID-induced gastrointestinal events among long-term users in the elderly. Drugs Aging 24 (2007) 121-131