N-terminal aliphatic residues dictate the structure, stability, assembly, and small molecule binding of the coiled-coil region of cartilage oligomeric matrix protein

Biochemistry

Volumn 48, Issue 36, 2009, Pages 8559-8567

  Gunasekar, Susheel K ^a   Asnani, Mukta ^a   Limbad, Chandani ^a   Haghpanah, Jennifer S ^a   Hom, Wendy ^a   Barra, Hanna ^a   Nanda, Soumya ^a   Lu, Min ^b   Montclare, Jin Kim ^a,c  

^a POLYTECHNIC UNIVERSITY   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c SUNY Downstate Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE-SCANNING MUTAGENESIS; ALL-TRANS-RETINOL; COILED COIL; COILED-COIL DOMAINS; CURCUMIN; HELICAL STRUCTURES; HYDROPHOBIC POCKETS; MATRIX PROTEINS; N-TERMINALS; POLAR RESIDUES; SMALL MOLECULES; SMALL-MOLECULE BINDINGS;

CARTILAGE; LIGAMENTS; MOLECULES; OLIGOMERIZATION;

STABILITY;

ALANINE; CALCITRIOL; CARTILAGE OLIGOMERIC MATRIX PROTEIN; CURCUMIN; RETINOL;

ALPHA HELIX; AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; CROSS LINKING; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; SITE DIRECTED MUTAGENESIS; THERMOSTABILITY;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; CURCUMIN; EXTRACELLULAR MATRIX PROTEINS; GLYCOPROTEINS; HUMANS; LEUCINE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN STABILITY; PROTEIN STRUCTURE, TERTIARY; RATS; VALINE; VITAMIN A; VITAMIN D;

EID: 70149086075     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi900534r     Document Type: Article

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