Non-steroidal anti-inflammatory drugs for the common cold

Cochrane Database of Systematic Reviews

Volumn , Issue 3, 2009, Pages

  Soo, Young Kim ^a   Chang, Yoon Jung ^b   Hye, Min Cho ^c   Hwang, Ye Won ^d   Yoo, Sun Moon ^e  

^a Kangdong Sacred Heart Hospital   (South Korea)

^b National Cancer Center   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d Korea University College of Medicine   (South Korea)

^e Hallym University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; FENOPROFEN; FENTIAZAC; IBUPROFEN; KETOPROFEN; LOXOPROFEN; NAPROXEN; NONSTEROID ANTIILAMMATORY AGENT; PLACEBO; UNCLASSIFIED DRUG;

ANALGESIA; ARTHRALGIA; CHILL; CLINICAL STUDY; CLINICAL TRIAL; COMMON COLD; COUGHING; DISEASE DURATION; DRUG ERUPTION; EDEMA; FOLLOW UP; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; MALAISE; METHODOLOGY; MYALGIA; OTALGIA; REVIEW; SNEEZING; SPUTUM; SYSTEMATIC ERROR; THROAT IRRITATION; TREATMENT OUTCOME;

EID: 70049097930     PISSN: 1469493X     EISSN: None     Source Type: Journal    
DOI: 10.1002/14651858.CD006362.pub2     Document Type: Review

References (67)

1. Goto M, Kawamura T, Shimbo T, Takahashi O, Ando M, Miyaki K, et al.Influence of loxoprofen use on recovery from naturally acquired upper respiratory tract infections: a randomized controlled trial. Internal Medicine 2006;46(15):1179-1186 (Pubitemid 47354434)
2. * Graham NM, Burrell CJ, Douglas RM, Debelle P, Davies L. Adverse effects of aspirin, acetaminophen, and ibuprofen on immune function, viral shedding, and clinical status in rhinovirus-infected volunteers. Journal of Infectious Diseases 1990;162(6):1277-1282
3. * Itoh K, Nagaoka S, Hamada A, Noguchi E, Suzuki H, Taniai T, et al.A double-blind clinical study of ketoprofen on acute upper respiratory infection - comparison with aspirin. Clinical Evaluation 1980;8(2):457-479
4. * Katsu M, Oishi A, Nakamura H, Matsuoka Y, Irimajiri S, Kobayashi H, et al.Clinical evaluation of loxoprofen sodium (CS-600E) on upper respiratory tract inflammation: a double blind controlled study in comparison with ibuprofen. Journal of Clinical Therapeutics and Medicines 1993;9(10):2299-2320
5. Nagaoka S, Nagahama F, Kunno K, Haga T, Ito K, Ito F, et al.Therapeutic effects of fentiazac on common cold - a double-blind clinical study. Clinical Evaluation 1980;8(3):757-788
6. Ryan PB, Rush DR, Nicholas TA, Graham DG. A double-blind comparison of fenoprofen calcium, acetaminophen, and placebo in the palliative treatment of common nonbacterial upper respiratory infections. Current Therapeutic Research, Clinical and Experimental 1987;41(1):17-23.
7. Sperber SJ, Sorrentino JV, Riker DK, Hayden FG. Evaluation of an alpha agonist alone and in combination with a nonsteroidal antiinflammatory agent in the treatment of experimental rhinovirus colds. Bulletin of the New York Academy of Medicine 1989;65(1):145-160
8. Sperber SJ, Hendley JO, Hayden FG, Riker DK, Sorrentino JV, Gwaltney JM Jr. Effects of naproxen on experimental rhinovirus colds. A randomized, double-blind, controlled trial Effects of naproxen on experimental rhinovirus colds. A randomized double-blind, controlled trial. Annals of Internal Medicine 1992;117(1):37-41.
9. Winther B, Mygind N. The therapeutic effectiveness of ibuprofen on the symptoms of naturally acquired common colds. American Journal of Rhinology 2001;15(4):239-242 (Pubitemid 32880940)
10. Aggarwal P, Ambrose C, Kumar M, Bhavani V, Bose E, Bose S, et al.Piroxicam versus ibuprofen as adjuncts to antibiotic therapy for symptomatic relief in upper respiratory infections: a perspective, randomized, comparative, multicentre study. Indian Practitioner 1997;50(11):939-947
11. Bachert C, Chuchalin AG, Eisebitt R, Netayzhenko VZ, Voelker M. Aspirin compared with acetaminophen in the treatment of fever and other symptoms of upper respiratory tract infection in adults; a multicenter, randomized, double-blind, double-dummy, placebo-controlled, parallel-group, single-dose, 6-hour dose-ranging study. Clinical Therapeutics 2005;27(7):993-1003. (Pubitemid 41262457)
12. Banchini G, Scaricabarozzi I, Montecorboli U, Ceccarelli A, Chiesa F, Ditri L, et al.Double-blind study of nimesulide in divers with inflammatory disorders of the ear, nose and throat. Drugs 1993;46(Suppl 1):100-102 (Pubitemid 23324622)
13. Batista NA, Zago MC, Schincarioli SM, Nader MC, Almeida J.Clinical evaluation of diclofenac resinate drops, associated to antibiotics, in the treatment of upper respiratory tract infections. Comparative study in pediatrics. Arquivos Brasileiros deMedicina 1985;59(6):479-484
14. Bellussi L, Passali D. Treatment of upper airways inflammation with nimesulide. Drugs 1993;46(Suppl 1):107-110 (Pubitemid 23324624)
15. Bellussi L, Biagini C, Calearo C, Cenacchi V, De Campora E, Di GirolamoA, et al.Antiphlogistic therapy with ketoprofen lysine salt vs nimesulide in secretive otitis media, rhinitis/rhinosinusitis, pharyngitis/tonsillitis/ tracheitis. Otorinolaringologia 1996;46(1):49-57. (Pubitemid 26186674)
16. Benrimoj SI, Langford JH, Christian J, Charlesworth A, Steans A. Efficacy and tolerability of the anti-inflammatory throat lozenge flurbiprofen 8.75mg in the treatment of sore throat a randomised, double-blind, placebo-controlled study. Clinical Drug Investigation 2001;21(3):183-193 (Pubitemid 32260707)
17. Bernstein JE, Nelson FK. A double blind evaluation of an aspirin containing gum tablet for relief of the pain of common sore throat. Journal of International Medical Research 1974;2(1):76-80.
18. Blagden M, Christian J, Miller K, Charlesworth A. Multidose flurbiprofen 8.75 mg lozenges in the treatment of sore throat: a randomised, double-blind, placebo-controlled study in UK general practice centres. International Journal of Clinical Practice 2002;56(2):95-100. (Pubitemid 34232981)
19. Bonifaci E, Giorgi CM, Vibelli C. Symptomatic management of acute inflammation of the upper airways in paediatric patients. Minerva Pediatrica 1977;29(5):285-296 (Pubitemid 8064264)
20. Cappella L, Guerra A, Laudizi L, Cavazzuti GB. Efficacy and tolerability of nimesulide and lysine-acetylsalicylate in the treatment of paediatric acute upper respiratory tract inflammation. Drugs 1993;46(Suppl 1):222-225 (Pubitemid 23324659)
21. Ebel DL, Shih WJ, Rhymer AR. A multi-centre, double-blind randomized study to assess the efficacy and tolerance of sulindac versus placebo in the symptomatic treatment of patients with upper respiratory tract infection. Current Medical Research and Opinion 1985;9(10):666-675
22. Eccles R, Loose I, Jawad M, Nyman L. Effects of acetylsalicylic acid on sore throat pain and other pain symptoms associated with acute upper respiratory tract infection. Pain Medicine 2003;4(2):118-124 (Pubitemid 36949868)
23. Fujimori I, Kono M, Takeda Y, Sekita K, Katsu M, Adachi M, et al.Clinical evaluation of Clinoril tablets in acute upper respiratory tract infections. Kansenshogaku Zasshi 1982;56(12):1186-1195
24. Fujimori I, Kono M, Sekita T, Takeda Y, Ogihara K, Nakagawa H, et al.A double-blind clinical evaluation of suprofen on acute upper respiratory infection. Comparison with aspirin. Kansenshogaku Zasshi 1983;57(1):62-81.
25. Gehanno P, Dreiser RL, Ionescu E, Gold M, Liu JM. Lowest effective single dose of diclofenac for antipyretic and analgesic effects in acute febrile sore throat. Clinical Drug Investigation 2003;23(4):263-271 (Pubitemid 36469964)
26. Gruber CM Jr, Collins T. Dose response to fenoprofen in an antipyretic study of fenoprofen and propoxyphene. Journal of Medicine 1977;8(1):27-34. (Pubitemid 8111540)
27. Kandoth PW, Joshi MK, Joshi VR, Satoskar RS. Comparative evaluation of antipyretic activity of ibuprofen and aspirin in children with pyrexia of varied aetiology. Journal of International Medical Research 1984;12(5):292-297
28. Katsu M, Mashita H, Fujimori I, Shimada S, Fujii T. Therapeutic effects of fenbufen in common cold - multi-clinic double blind study. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1977;51(4):184-196
29. Katsu M, Fujii T, Fujimori I, Katayama T, Harada K, Koizumi H, et al.Therapeutic utility of naproxen on acute upper respiratory infection - multi-clinical double blind study. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1978;52(5):148-163
30. Katsu M, Hayakawa M, Kawai M, Fujimori I, Kohno M, Takeda Y, et al.Double blind controlled study of miroprofen in acute upper respiratory tract infections - comparison with ibuprofen. Kansenshogaku Zasshi 1982;56(5):434-453
31. Katsu M, Adachi M, Hayakawa M, Fujimori I, Kohno M, Takeda Y, et al.Clinical evaluation of sulindac (CLINORIL) in the treatment of acute upper respiratory tract infection - double-blind comparison with ibuprofen. Kansenshogaku Zasshi 1983;57(3):260-272
32. Kierszenbaum J, Vitral BG, Kierszenbaum AML, de Sousa PR. Evaluation of nimesulid oral suspension versus diclofenac resinate in upper respiratory tract infections in the pediatrics. Pediatria Moderna 1991;27(7):560-562
33. Lopes FO. Amoxicillin versus amoxicillin + nimesulide in otolaryngologic infections - A randomized study. FolhaMedica 1991;102(3):81-85
34. Martinez Gallardo F, Lopez Fiesco A, Zamora G. Symptomatic treatment of common cold in children with a new combination of naproxen sodium plus pseudoephedrine hydrochloride: a comparative trial against pseudoephedrine syrup. Proceedings of the Western Pharmacology Society 1994;37:157-158 (Pubitemid 24224439)
35. Matsumoto K, Fujimori I, Tsubura E, Sakuma A, Hayashi M, Kudo K, et al.Clinical evaluation of oxaprozin in the treatment of acute upper respiratory tract inflammations - a double-blind comparative study using ibuprofen as the control drug. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1984;58(7):628-646
36. Moore N, Le Parc JM, van Ganse E, Wall R, Schneid H, Cairns R. Tolerability of ibuprofen, aspirin and paracetamol for the treatment of cold and flu symptoms and sore throat pain. International Journal of Clinical Practice 2002;56(10):732-734 (Pubitemid 36104536)
37. Nagaoka S, Fumio N, Ohito O, Hideyo N, Morise M, Osamu T, et al.Clinical effect of floctafenine in acute upper respiratory infection: a double blind test in comparison with aspirin. Japanese Pharmacology and Therapeutics 1985;13(2):981-1010.
38. Nagaoka S, Hiraga H, Ohito O, Hideyo N, Suetsugu S, Osamu T, et al.Clinical effect of emorfazone in acute upper respiratory infection: a double blind test in comparison with aspirin. Japanese Pharmacology and Therapeutics 1986;14(9):5883-5900
39. Nagaoka S, Nakamura S, Umehara Y, Nagahama F, Okayasu M, Noguchi E, et al.Clinical evaluation of tolfenamic acid on acute upper respiratory tract inflammation: multi-center double-blind study with ibuprofen. Journal of Clinical Therapeutics and Medicines 1986;2(2):221-250
40. Nouri ME. Nimesulide for treatment of acute inflammation of the upper respiratory tract. Clinical Therapeutics 1984;6(2):142-150 (Pubitemid 14151375)
41. Nouri E, Monti T. Nimesulide granules for the treatment of acute inflammation of the ear, nose or throat. Drugs 1993;46(Suppl 1):103-106 (Pubitemid 23324623)
42. Pagella F, Rossi V, Zanoletti E, Benazzo M, Mira E. Efficacy and tolerability of a mouthwash based on diclofenac in the treatment of disorders of the upper respiratory tract. Double blind study versus flurbiprofen mouthwash. Otorinolaringologia 2001;51(2):77-81. (Pubitemid 32852728)
43. Passali D, Bellussi L, Ciferri G, Scaricabarozzi I. Use of nimesulide in inflammations of the upper respiratory tract. Clinica Terapeutica 1989;128(2):105-111 (Pubitemid 19265952)
44. Passali D, Gorga A, Ferri R, Bellussi L. Controlled clinical study on the efficacy and tolerability of methoxibutropate versus nimesulide in otorhinolaryngology. Otorinolaringologia 1997;47(3):145-150 (Pubitemid 27512587)
45. Reiner M.Nimesulide and antibiotics in the treatment of acute infections of the respiratory tract. Current Medical Research and Opinion 1983;8(7):487-492
46. Salmon Rodriguez LE, Arista Viveros A, Lopez y Martinez E, Trujillo C, Maciel R, Lujan M. Evaluation of the efficacy and safety of nimesulide and naproxen in the symptomatic treatment of upper respiratory tract infections in children. A comparative blind study. Investigacion Medica Internacional 1993;20(2):43-54. (Pubitemid 24270451)
47. Salzberg R, Giambonini S, Maurizio M, Roulet D, Zahn J, Monti T. A double-blind comparison of nimesulide and mefenamic acid in the treatment of acute upper respiratory tract infections in children. Drugs 1993;46(Suppl 1):208-211 (Pubitemid 23324655)
48. Sanchez Gonzalez A, Gonzalez Galindo T, Santana Hurtado O. Efficacy and safety assessment of tolmetin sodium (400 mg tid) vs naproxen sodium(275mg tid) for the treatment of acute upper respiratory tract infection symptoms. Investigacion Medica Internacional 1999;26(1):3-8. (Pubitemid 30040748)
49. Schachtel BP, Thoden WR. A placebo-controlled model for assaying systemic analgesics in children. Clinical Pharmacology and Therapeutics 1993;53(5):593-601.
50. Schachtel BP, Homan HD, Gibb IA, Christian J. Demonstration of dose response of flurbiprofen lozenges with the sore throat pain model. Clinical Pharmacology and Therapeutics 2002;71(5):375-380 (Pubitemid 34518148)
51. Stanley ED, Jackson GG, Panusarn C, Rubenis M, Dirda V. Increased virus shedding with aspirin treatment of rhinovirus infection. JAMA 1975;231(12):1248-1251
52. Tamura M, Ito T, Sudo M, Tazawa M, Sayama T, Yoshida M, et al.A double-blind clinical evaluation of flurbiprofen on acute upper respiratory tract inflammation - comparative study with ibuprofen. Kansenshogaku Zasshi 1984;58(12):1289-1303
53. Ulukol B, Koksal Y, Cin S. Assessment of the efficacy and safety of paracetamol, ibuprofen and nimesulide in children with upper respiratory tract infections. European Journal of Clinical Pharmacology 1999;55(9):615-618
54. Vauzelle-Kervroedan F, Revzani Y, Pons G, Consten L, Pariente- Khayat A, d'Athis P, et al.Antipyretic efficacy of tiaprofenic acid in febrile children. Fundamental Clinical Pharmacology 1996;10(1):56-59 (Pubitemid 26078594)
55. Watson N, Nimmo WS, Christian J, Charlesworth A, Speight J, Miller K. Relief of sore throat with the anti-inflammatory throat lozenge flurbiprofen 8.75mg: A randomised, double-blind, placebo-controlled study of efficacy and safety. International Journal of Clinical Practice 2000;54(8):490-496 (Pubitemid 30848060)
56. De Sutter AIM, Lemiengre M, Campbell H. Antihistamines for the common cold. Cochrane Database of Systematic Reviews 2003, Issue 3. [DOI: 10.1002/14651858.CD001267]
57. Eccles R. Understanding the symptoms of the common cold and influenza. Lancet Infectious Diseases 2005;5:718-725 (Pubitemid 41505360)
58. Gwaltney JM. Viral respiratory infection therapy: historical perspectives and current trials. American Journal of Medicine 2002;112(Suppl):33-41.
59. Heikkinen T, Jarvinen A Heikkinen T, Jarvinen A. The common cold. Lancet 2003;361(9351):51-59
60. Higgins JPT, Altman DG (editors). Chapter 8: Assessing risk of bias in included studies.. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions 5.0.0 [updated February 2008]. Chichester, UK: Wiley-Blackwell, February 2008 (Available from www.cochrane-handbook.org).
61. Irwin RS, Madison JM. The diagnosis and treatment of cough. New England Journal of Medicine 2000;343(23):1715-1721
62. Lefebvre C, Manheimer E, Glanville J. Cochrane Highly Sensitive Search Strategy for identifying randomized trials in MEDLINE: sensitivity-maximizing version (2008 revision); PubMed format. In: Higgins JPT, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions. Chichester, UK: Wiley-Blackwell, 2008.
63. Ostberg B, Winther B, Borum P, Mygind N. Common cold and high-dose ipratroiium bromide: use of anticholinergic medication as an indicator of reflex-mediated hypersecretion. Rhinology 1997;35(2):58-62. (Pubitemid 27376787)
64. Pratter MR. Cough and the common cold: ACCP evidence-based clinical practice guidelines. Chest 2006;129(Suppl 1):72-74
65. Smith SM, Schroeder K, Fahey T. Over-the-counter medications for acute cough in chilren and adults in ambulatory settings. Cochrane Database of Systematic Reviews 2008, Issue 1. [DOI: 10.1002/14651858.CD001831.pub3] (Pubitemid 351807643)
66. Taverner D, Latte J. Nasal decongestants for the common cold. Cochrane Database of Systematic Reviews 2007, Issue 1. [DOI: 10.1002/14651858.CD001953. pub3]
67. Winther B, Mygind N. The therapeutic effectiveness of ibuprofen on the symptoms of naturally acquired common colds. American Journal of Rhinology 2001;15(4):239-242 (Pubitemid 32880940)