Influence of ABCB1 polymorphisms and haplotypes on tacrolimus nephrotoxicity and dosage requirements in children with liver transplant

British Journal of Clinical Pharmacology

Volumn 68, Issue 3, 2009, Pages 413-421

  Hawwa, Ahmed F ^a   McKiernan, Patrick J ^b   Shields, Michael ^c   Millership, Jeff S ^a   Collier, Paul S ^a   McElnay, James C ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b BIRMINGHAM CHILDREN S HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^c ROYAL BELFAST HOSPITAL FOR SICK CHILDREN   (United Kingdom)

Author keywords

Immunosuppressant; Liver transplantation; P glycoprotein; Pharmacogenomics; Tacrolimus

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MULTIDRUG RESISTANCE PROTEIN 1; TACROLIMUS;

ADOLESCENT; ARTICLE; CHILD; CONTROLLED STUDY; DRUG BLOOD LEVEL; EVENING DOSAGE; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETIC VARIABILITY; GENOTYPE; GLOMERULUS FILTRATION RATE; HAPLOTYPE; HETEROZYGOTE; HUMAN; INFANT; KIDNEY DYSFUNCTION; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; NEPHROTOXICITY; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; CHILD; FEMALE; GENE FREQUENCY; GENOTYPE; GLOMERULAR FILTRATION RATE; HAPLOTYPES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; LIVER TRANSPLANTATION; MALE; P-GLYCOPROTEIN; POLYMORPHISM, SINGLE NUCLEOTIDE; TACROLIMUS;

EID: 69949154760     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2009.03461.x     Document Type: Article

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