메뉴 건너뛰기




Volumn 47, Issue SUPPL. 5, 2009, Pages

Pro- and anti-fibrotic effects of TGF-β in scleroderma

Author keywords

Fibrosis; Systemic sclerosis; The University of California at Davis 200 chicken; Transforming growth factor ; Transforming growth factor 2; Transforming growth factor 3

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 3; COLLAGEN TYPE 6; MESSENGER RNA; PLACEBO; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; TRANSFORMING GROWTH FACTOR BETA3;

EID: 69949140810     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ken275     Document Type: Conference Paper
Times cited : (11)

References (10)
  • 1
    • 0029999963 scopus 로고    scopus 로고
    • Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma
    • Sgonc R, Gruschwitz M, Dietrich H, Recheis H, Gershwin ME, Wick G. Endothelial cell apoptosis is a primary pathogenetic event underlying skin lesions in avian and human scleroderma. J Clin Invest 1996;98:785-92.
    • (1996) J Clin Invest , vol.98 , pp. 785-792
    • Sgonc, R.1    Gruschwitz, M.2    Dietrich, H.3    Recheis, H.4    Gershwin, M.E.5    Wick, G.6
  • 2
    • 33751501713 scopus 로고    scopus 로고
    • Avian models with spontaneous autoimmune diseases
    • Wick G, Andersson L, Hala K et al. Avian models with spontaneous autoimmune diseases. Adv Immunol 2006;92:71-117.
    • (2006) Adv Immunol , vol.92 , pp. 71-117
    • Wick, G.1    Andersson, L.2    Hala, K.3
  • 3
  • 4
    • 0026779982 scopus 로고
    • Cultured fibroblasts in avian scleroderma, an autoimmune fibrotic disease, display an activated phenotype
    • Duncan MR, Wilson TJ, Van De Water J et al. Cultured fibroblasts in avian scleroderma, an autoimmune fibrotic disease, display an activated phenotype. J Autoimmunity 1992;5:603-15.
    • (1992) J Autoimmunity , vol.5 , pp. 603-615
    • Duncan, M.R.1    Wilson, T.J.2    Van De Water, J.3
  • 5
    • 0028800468 scopus 로고
    • Genomic analysis of collagen and endogenous virus loci in the UCD-200 and 206 lines of chickens, animal models for scleroderma
    • Sgonc R, Dietrich H, Gershwin ME, Colombatti A, Wick G. Genomic analysis of collagen and endogenous virus loci in the UCD-200 and 206 lines of chickens, animal models for scleroderma. J Autoimmunity 1995;8:763-70.
    • (1995) J Autoimmunity , vol.8 , pp. 763-770
    • Sgonc, R.1    Dietrich, H.2    Gershwin, M.E.3    Colombatti, A.4    Wick, G.5
  • 6
    • 0031458231 scopus 로고    scopus 로고
    • Altered procollagen mRNA expression during the progression of avian scleroderma
    • Ausserlechner MJ, Sgonc R, Dietrich H, Wick G. Altered procollagen mRNA expression during the progression of avian scleroderma. Mol Med 1997;3:654-62.
    • (1997) Mol Med , vol.3 , pp. 654-662
    • Ausserlechner, M.J.1    Sgonc, R.2    Dietrich, H.3    Wick, G.4
  • 7
    • 33748551701 scopus 로고    scopus 로고
    • Leask A. Scar wars: Is TGFβ the phantom menace in scleroderma? Arthritis Res Ther 2006;8:213-19.
    • Leask A. Scar wars: Is TGFβ the phantom menace in scleroderma? Arthritis Res Ther 2006;8:213-19.
  • 8
    • 20744455828 scopus 로고    scopus 로고
    • Diminished TGF-β2 production leads to increased expression of a profibrotic procollagen alpha 2 type I mRNA variant in embryonic fibroblasts of UCD-200 chickens, a model for systemic sclerosis
    • Prelog M, Scheidegger P, Peter S, Gershwin ME, Wick G, Sgonc R. Diminished TGF-β2 production leads to increased expression of a profibrotic procollagen alpha 2 type I mRNA variant in embryonic fibroblasts of UCD-200 chickens, a model for systemic sclerosis. Arthritis Rheum 2005;52:1804-11.
    • (2005) Arthritis Rheum , vol.52 , pp. 1804-1811
    • Prelog, M.1    Scheidegger, P.2    Peter, S.3    Gershwin, M.E.4    Wick, G.5    Sgonc, R.6
  • 9
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human disease
    • Blobe M, Schiemann WP, Lodish HF. Role of transforming growth factor beta in human disease. N Engl J Med 2000;342:1350-8.
    • (2000) N Engl J Med , vol.342 , pp. 1350-1358
    • Blobe, M.1    Schiemann, W.P.2    Lodish, H.F.3
  • 10
    • 33846250366 scopus 로고    scopus 로고
    • Cat-192 Study Group; Scleroderma Clinical Trials Consortium. Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: A multicenter, randomized, placebo-controlled phase I/II trial of CAT-192
    • Denton CP, Merkel PA, Furst DE et al. Cat-192 Study Group; Scleroderma Clinical Trials Consortium. Recombinant human anti-transforming growth factor beta1 antibody therapy in systemic sclerosis: A multicenter, randomized, placebo-controlled phase I/II trial of CAT-192. Arthritis Rheum 2007;56:323-33.
    • (2007) Arthritis Rheum , vol.56 , pp. 323-333
    • Denton, C.P.1    Merkel, P.A.2    Furst, D.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.