Enhanced uridine diphosphate N-acetylglucosamine production using whole-cell catalysis

Applied Microbiology and Biotechnology

Volumn 84, Issue 4, 2009, Pages 677-683

  Ying, Hanjie ^a   Chen, Xiaochun ^a   Cao, Haiping ^a   Xiong, Jian ^a   Hong, Yuan ^a   Bai, Jianxin ^a   Li, Zhenjiang ^a  

^a NANJING TECH UNIVERSITY   (China)

Author keywords

ATP utilization efficiency; Response surface methodology; Saccharomyces cerevisiae; Uridine diphosphate N acetylglucosamine

Indexed keywords

ATP UTILIZATION EFFICIENCY; CATALYTIC CONDITIONS; CENTRAL COMPOSITE DESIGNS; CONVERSION YIELD; CULTIVATION CONDITIONS; DIHYDROGEN PHOSPHATE; DIPHOSPHATES; FRACTIONAL FACTORIAL DESIGNS; GLUCOSAMINES; MAGNESIUM CHLORIDES; MONOPHOSPHATES; N-ACETYLGLUCOSAMINE; OPTIMIZATION STRATEGY; POTASSIUM CHLORIDE; RESPONSE SURFACE ANALYSIS; RESPONSE SURFACE METHODOLOGY; SACCHAROMYCES CEREVISIAE; SODIUM ACETATE; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE; UTILIZATION EFFICIENCY; VITAMINB1;

CATALYSIS; CELL MEMBRANES; CHLORINE COMPOUNDS; CULTIVATION; GLYCEROL; MAGNESIUM; OPTIMIZATION; PH EFFECTS; POTASSIUM; SODIUM; SURFACE ANALYSIS; SURFACE PROPERTIES; YEAST;

VITAMINS;

ACETIC ACID; FRUCTOSE; GLUCOSAMINE; GLYCEROL; MAGNESIUM CHLORIDE; POTASSIUM CHLORIDE; SODIUM DIHYDROGEN PHOSPHATE; THIAMINE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; URIDINE PHOSPHATE;

CATALYSIS; FERMENTATION; MAGNESIUM; METABOLISM; OPTIMIZATION; VITAMIN; YEAST;

ARTICLE; ATP UTILIZATION EFFICIENCY; CATALYSIS; CENTRAL COMPOSITE DESIGN; CONCENTRATION RESPONSE; CULTURE MEDIUM; ENERGY EXPENDITURE; FACTORIAL DESIGN; FRACTIONAL FACTORIAL DESIGN; MATHEMATICAL PHENOMENA; NONHUMAN; PH; REPRODUCIBILITY; RESPONSE SURFACE METHOD; SACCHAROMYCES CEREVISIAE; SYNTHESIS; TECHNIQUE; TEMPERATURE DEPENDENCE; WHOLE CELL;

BIOTECHNOLOGY; CATALYSIS; CULTURE MEDIA; SACCHAROMYCES CEREVISIAE; TEMPERATURE; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE;

SACCHAROMYCES CEREVISIAE;

EID: 69949118438     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-009-2016-6     Document Type: Article

References (18)

1. T Bülter L Elling 1999 Enzymatic synthesis of nucleotide sugars Glycoconjugate J 16 147 159
2. XC Chen JX Bai JM Cao ZJ Li J Xiong L Zhang Y Hong HJ Ying 2009 Medium optimization for the production of cyclic adenosine 3′, 5′ -monophosphate by Microbacterium sp. no. 205 using response surface methodology Bioresour Technol 100 919 924
3. JE Heidlas WJ Lees P Pale GM Whitesides 1992 Gram-scale synthesis of uridine 5′-diphospho-N-acetylglucosamine: comparison of enzymatic and chemical routes J Org Chem 57 146 151
4. T Ishige K Honda S Shimizu 2005 Whole organism catalysis Curr Opin Chem Biol 9 174 180
5. L Lang S Kornefeld 1984 A simplified procedure for synthesizing large quantities of highly purified uridine diphospho-N-acetylglucosamine Anal Biochem 140 264 269
6. JS Li CQ Ma YH Ma Y Li W Zhou P Xu 2007 Medium optimization by combination of response surface methodology and desirability function: an application in glutamine production Appl Microbiol Biotechnol 74 563 571 (Pubitemid 46295006)
7. S Milewski I Gabriel J Olchowy 2006 Enzymes of UDP-GlcNAc biosynthesis in yeast Yeast 23 1 14
8. K Okuyama T Hamamoto K Ishige K Takenouchi T Noguchi 2000 An efficient method for production of uridine-5′ -diphospho-N-acetylglucosamine Biosci Biotechnol Biochem 64 386 392
9. MM Palcic 1999 Biocatalytic synthesis of oligosaccharides Curr Opin Biotechnol 10 616 624
10. FC Sampaio DD Faveri HC Mantovani FM LopesPassosa P Perego A Converti 2006 Use of response surface methodology for optimization of xylitol production by the new yeast strain Debaryomyces hansenii UFV-170 J Food Eng 76 376 386
11. KG Sonia BS Chadha HS Saini 2005 Sorghum straw for xylanase hyper-production by Thermomyces lanuginosus (D2W3) under solid-state fermentation Bioresour Technol 96 1561 1569
12. Takenouchi K, Ishige K, Midorikawa Y, Okuyama K, Hamamoto T, Noguchi T (2001) Process for producing uridine diphosphate N-acetlyglucosamine. US Patent 6,287,819 B1
13. XJ Tang GQ He QH Chen XY Zhang MAM Ali 2004 Medium optimization for the production of thermal stable b-glucanase by Bacillus subtilis ZJF-1A5 using response surface methodology Bioresour Technol 93 175 181
14. T Tochikura H Kawai T Gotan 1971 Studies on microbial metabolism of sugar nucleotides Part VI. Fermentive production of UDP-N-acetylglucosamine from 5′-UMP and glucosamine by yeast Agric Biol Chem 35 163 176
15. Tomita M, Mukai H (1997) Method for producing uridine diphosphate N-acetylgluosamine. US Patent 5,674,715
16. X Wang CQ Ma XW Wang P Xu 2007 Orotate phosphoribosyltransferase from Corynebacterium ammoniagenes lacking a conserved lysine J Bacteriol 189 9030 9036
17. X Wang XW Wang MX Yin ZJ Xiao CQ Ma ZX Lin PG Wang P Xu 2007 Production of uridine 5′-monophosphate by Corynebacterium ammoniagenes ATCC 6872 using a statistically improved biocatalytic process Appl Microbiol Biotechnol 76 321 328
18. ZJ Xiao PH Liu JY Qin P Xu 2007 Statistical optimization of medium components for enhanced acetoin production from molasses and soybean meal hydrolysate Appl Microbiol Biotechnol 74 61 68