Bioactivity-guided isolation of cytotoxic constituents from stem-bark of Premna tomentosa

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 19, 2009, Pages 5727-5731

  Hymavathi, A ^a   Suresh Babu, K ^a   Naidu, V G M ^a   Rama Krishna, S ^a   Diwan, Prakash V ^a   Madhusudana Rao, J ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

Cytotoxic activity; Diterpenoids; Icetexanes; Premna tomentosa; Verbenaceae

Indexed keywords

2 (4 METHOXYPHENYL) 2 BUTANONE; ANTINEOPLASTIC AGENT; BETULIN; CONIFERALDEHYDE; DITERPENE; LUPEOL; SYRINGALDEHYDE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BARK; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN HEPG2; CELL STRAIN HT29; CELL STRAIN MCF 7; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFECT; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; FRACTIONATION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; NONHUMAN; PLANT STEM; PREMNA TOMENTOSA; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DITERPENES; DRUG SCREENING ASSAYS, ANTITUMOR; HT29 CELLS; HUMANS; MOLECULAR CONFORMATION; PLANT BARK; VERBENACEAE;

PREMNA TOMENTOSA; VERBENACEAE;

EID: 69949107726     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.08.002     Document Type: Article

References (29)

1. Kadereit, J. W. The Families and Genera of Vascular Plants; Springer, Berlin, 2004; Vol. VII, p 449.
2. Shanmugavelu M. Sidhacure for Diseases (1987), Tamil Nadu Siddha Medical Board Publications, Chennai, India
3. In: Krishnamurthy A. (Ed). The Wealth of India: Raw Materials Vol. VIII (1969), CSIR, New Delhi, India 240-241
4. Devi K., and Devaki T. Med. Sci. Res. 26 (1998) 785
5. Devi K., Anadam R., Devaki T., Apparanatham T., and Balakrishna K. Biomed. Res. 19 (1998) 339
6. Devi K.P., Sreepriya M., Balakrishna K., Veluchamy G., and Devaki T. J. Alter. Compl. Med. 10 (2004) 540
7. Devi K.P., Sairam M., Sreepriya M., Ilavazhagan G., and Devak T. Biomed. Pharmacather. 57 (2003) 105
8. Devi K.P., Sreepriya M., Balakrishna K., and Devaki T. Mol. Caller Biochem. 272 (2005) 171
9. Chin W., Jones W.P., Mi Q., Rachman I., Riswan S., Kardono L.B.S., Chai H.B., Fransworth N.R., Cordell G.A., and Swanson S.M. Phytochemistry 67 (2006) 1243
10. Alam M., Joy S., Susan T., and Usman Ali S. Ancient Sci. 13 (1993) 185
11. Etti S., Shanmugam G., Ponnuswamy M.N., Balakrishna K., and Vasanth S. Acta Crystallogr., Sect. E 61 (2005) 846
12. Robinson A., Vijay Kumar T., Sreedhar E., Naidu V.G.M., Ramakrishna S., Sureshbabu K., Srinivas P.V., and Rao J.M. Bioorg. Med. Chem. Lett. 18 (2008) 4015
13. Fraga B.M., Diaz C.E., Guadano A., and González-Coloma A. J. Agric. Food Chem. 53 (2005) 5200
14. Uchiyama N., Kiuchi F., Ito M., Honda G., Takeda Y., Khodzimatov O.K., and Ashurmetov O.A. J. Nat. Prod. 66 (2003) 128
15. Shen Y.-C., Wang S.-S., Chien C.-T., Kuo Y.-H., and Khalil A.T. J. Nat. Prod. 71 (2008) 576
16. Patra A., Choudhary S.K., and Panda S.K. J. Nat. Prod. 51 (1988) 217
17. Creighton R.H.J., McCarthy J.L., and Hibbert H. J. Am. Chem. Soc. 63 (1941) 312
18. Starrat A.N. Phytochemistry 12 (1973) 231
19. Lin T.-C., Fang J.-M., and Cheng Y.-S. Phytochemistry 51 (1999) 793
20. Waterman P.G., and Ampofo S. Phytochemistry 24 (1985) 2925
21. http://www.atcc.org/pdf/30-1010k.pdf.
22. Miyase T., Ruedi P., and Eugster C.H. Helv. Chim. Acta 60 (1977) 2789
23. Alphonse K. Tetrahedron 39 (1983) 3603
24. Burno M., Savona G., Piozzi F., and Torre M.C. Phytochemistry 30 (1991) 2339
25. Torre M.C., Burno M., Rodgriguez B., and Savona G. Phytochemistry 31 (1992) 3953
26. Anam E.M. Indian J. Chem. 37B (1998) 1307
27. Esquivel B., Flores M., Hernandez-Ortega S., Toscano R.A., and Ramamoorthy T.P. Phytochemistry 39 (1995) 139
28. Xu G., Peng L.-Y., Li X.-L., Tu L., Zhao Q.-S., and Sun H.-D. Chem. Pharm. Bull. 53 (2005) 1575
29. Simmons E.M., Yen J.R., and Sarpong R. Org. Lett. 9 (2007) 2705