Protective effect of Premna tomentosa on acetaminophen-induced acute hepatitis in rats

Medical Science Research

Volumn 26, Issue 11, 1998, Pages 785-787

  Pandima Devi, K ^a   Devaki, T ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Acetaminophen; Alkaline phosphatase; Blood urea; Glutamate pyruvate transaminase; Heptaprotectivity; Lactate dehydrogenase; Premna tomentosa; Serum bilirubin; Serum glutamate; Tissue lipid peroxides; Transaminase

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; LACTATE DEHYDROGENASE; LIPID PEROXIDE; LIVER PROTECTIVE AGENT; PARACETAMOL; PLANT EXTRACT; UREA;

ACUTE HEPATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILIRUBIN BLOOD LEVEL; CONTROLLED STUDY; DRUG INDUCED DISEASE; ENZYME BLOOD LEVEL; LIPID PEROXIDATION; LIVER PROTECTION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; UREA BLOOD LEVEL;

ANIMALIA; PREMNA; PREMNA TOMENTOSA;

EID: 0031773682     PISSN: 02698951     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Mitchell LD, Jollow DJ. Potter WZ, Davis DC, Gillette JR, Brodie BB. Acetaminophen induced hepatic necrosis I. Role of drug metabolism. J Pharmacol Exp Ther 1973: 187(1):185-194.
2. Lin CC, Tsai CC, Yen MH. The evaluation of hepatoprotective effects of Taiwan folk medicine 'Teng-Khia-U'. J Ethnopharmacol 1995; 45:113-123.
3. Slater TF. Biochemical studies on liver injury. In: Biochemical mechanism of liver injury. London:Academic Press: 1965. pp. 1-44.
4. Haines HH. The Botany of Bihar and Orissa. Vol. II. Calcutta: Sri Gowri Ganga Press Private Limited; 1961. pp. 753.
5. Shanmugavelu M. Siddha cuir for diseases Part 1. Chennai: Tamilnadu Siddha Medicine Board Publications: 1987. p. 288.
6. Chopra RN, Nayar SL. Chopra 1C. Glossary of Indian Medicinal Plants New Delhi: Council of Scientific and Industrial Research, p. 203.
7. The wealth of India Raw Materials. New Delhi: Council of Scientific and Industrial Research, 1989. pp. 240-241.
8. Janhaz KH. Gilani HA. Evaluation of the protective potential of Artemisia maritima extract on acetaminophcn and CCl induced liver damage. J Ethnopharmacol 1995; 47:43-47.
9. Reitman S, Frankel S. A colorimetric method for determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases. Am J Clin Pathol 1957: 28:56-63.
10. King EJ. Lactate dehydrogcnase. In: Practical Clinical En-ymolt>gy. London: D. Van Nostrand Co: 1965. pp. 83-93.
11. Kind PRN. King EJ. Estimation of plasma phosphatase by determination of hydrolysed phenol with antipyrene. J Clin Pathol 1954; 7:322-330.
12. Ohkawa H. Ohishi N. Yagi K. Assay of lipid peroxides in animal tissues by thiobarbituric acid reaction. Annal Biochem 1979; 95:361-358.
13. Moron MS. Depierrre JW. Mannervik B. Levels of glutathione, glutathione reductase and glutathione-S-transferase activities in rat lung and liver. Biochim Biophys Acui 1979: 582:62.
14. Malloy HT, Evelyn KA. The determination of biliruhin with the photometric colorimeter. Biol Chem 1937: 119:481-490.
15. Varley H, Gowenlock AH, Bell M. Practical Clinical Chemistry. In: Curtis HC, Roth M (editors) Nonprotein nitrogenous compounds 1974. Walter de Gruyter, New York, pp. 1122-1129.
16. Chenoweth MB, Hake CL. The smaller halogenated aliphatic hydrocarbons. Ann Rev Plmrmacol 1962; 2:363-398.
17. Sallie R. Tredger JM, Wiliam R. Drugs and the liver. Biopharmaceut Drug Dispos 1991; 12:251-259.
18. Jaya DS. Augstine J. Menon VP. Protective effect of testosterone against alcohol and paracetamol induced hepatotoxicity in rats, tncl J Exp Biol 1995; 33:194-200.
19. Slater TF. Free radical mechanisms in tissue injury. Biochem J 1984; 222:1-15.
20. Jaya DS. Augstine J. Menon VP. Role of lipid peroxides and antiperoxidative enzymes in alcohol and drug toxicity. Iml J Exp Biol 1993: 31:453-459.
21. Mathcws AM. Hinson JA, Roberts DW. Pumford NR. Comparison of covalent binding of acetaminophen and the regioisomer 3'-hydroxyacetanilide to mouse liver proteins. Tnxicol Lett 1997; 90(l):77-82.
22. Mitchell JR. Covalent binding : useful index of the formation of chemically reactive drug metabolites. Biochem Soc Trans 1975: 3(5):622-626.