Decreased PM10 exposure attenuates age-related lung function decline: Genetic variants in p53, p21, and CCND1 modify this effect

Environmental Health Perspectives

Volumn 117, Issue 9, 2009, Pages 1420-1427

  Imboden, Medea ^a,b   Schwartz, Joel ^c   Schindler, Christian ^d   Curjuric, Ivan ^a,d   Berger, Wolfgang ^b   Liu, Sally L J ^d   Russi, Erich W ^e   Ackermann Liebrich, Ursula ^d   Rochat, Thierry ^f   Probst Hensch, Nicole M ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^e UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^f GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

Air pollution; Cell cycle; Cohort study; Genes; Respiratory function tests

Indexed keywords

CYCLIN D1; PROTEIN P21; PROTEIN P53; CCND1 PROTEIN, HUMAN; PRIMER DNA;

ADULT; AIR POLLUTION; AIR QUALITY; ARTICLE; CELL CYCLE REGULATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; FOLLOW UP; FORCED EXPIRATORY FLOW; FORCED EXPIRATORY VOLUME; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; LUNG DISEASE; LUNG FUNCTION; MALE; MEDICAL ASSESSMENT; NORMAL HUMAN; PARTICLE SIZE; PARTICULATE MATTER; PRIORITY JOURNAL; QUESTIONNAIRE; RESPIRATORY FUNCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SPIROMETRY; SWITZERLAND; AIR POLLUTANT; COHORT ANALYSIS; DRUG EFFECT; GENETICS; LUNG; LUNG FUNCTION TEST; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TUMOR SUPPRESSOR GENE;

ADULT; AIR POLLUTANTS; BASE SEQUENCE; COHORT STUDIES; CYCLIN D1; DNA PRIMERS; FEMALE; GENES, P53; GENETIC VARIATION; HUMANS; LUNG; MALE; PARTICLE SIZE; PROTO-ONCOGENE PROTEINS P21(RAS); RESPIRATORY FUNCTION TESTS;

EID: 69949092736     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0800430     Document Type: Article

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