LET dependence of the formation of oxidative damage 8-hydroxy-2′-deoxyguanosine (8-OHdG) in 2′-deoxyguanosine aqueous solution irradiated with heavy ions

Radiation Physics and Chemistry

Volumn 78, Issue 12, 2009, Pages 1207-1210

  Hirayama, Ryoichi ^a   Furusawa, Yoshiya ^a   Murayama, Chieko ^b   Kusano, Yosuke ^c   Ito, Atsushi ^b  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b TOKAI UNIVERSITY   (Japan)

^c Inage ku   (Japan)

Author keywords

8 OHdG; DNA base; Heavy ion; LET; Oxidative damage; Oxygen effect

Indexed keywords

8-OHDG; AQUEOUS SOLUTIONS; BIOLOGICAL EFFECTS; ION SPECIES; IRRADIATION CONDITIONS; LET; LET RADIATION; OH RADICAL; OXIDATIVE DAMAGE; OXYGEN EFFECT;

BIOMOLECULES; DNA; FREE RADICAL REACTIONS; FREE RADICALS; GENES; HEAVY IONS; NUCLEIC ACIDS; OXYGEN;

LIGHTING FIXTURES;

8 HYDROXYDEOXYGUANOSINE; CARBON; DEOXYGUANOSINE; DNA BASE; HEAVY ION; NEON; OXYGEN; SILICON;

AQUEOUS SOLUTION; ARTICLE; CELL ACTIVATION; DNA DAMAGE; IONIZING RADIATION; IRRADIATION; OXIDATIVE STRESS; RELIABILITY; REPRODUCIBILITY;

EID: 69949087303     PISSN: 0969806X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radphyschem.2009.07.012     Document Type: Article

References (23)

1. Appleby A., Christman E.A., and Jayko M. Radiation chemistry of high-energy carbon, neon, and argon ions: hydroxyl radical yields. Radiat. Res. 104 (1985) 263-271
2. Baverstock K.F., and Burns W.G. Oxygen as a product of water radiolysis in high-LET tracks II. Radiobiological implications. Radiat. Res. 86 (1981) 20-33
3. Bisby R.H., Cundall R.B., Sims H.E., and Burns W.G. The inactivation of papain by high LET radiations. Int. J. Radiat. Biol. 46 (1984) 261-268
4. Burns W.G., and Sims H.E. Effects of radiation type in water radiolysis. J. Chem. Soc., Faraday Trans. 1. 77 (1981) 2803-2813
5. Burr N.F., and Schuler R.H. The dependence of radical and molecular yields on linear energy transfer in the radiation decomposition of 0.8 N sulfuric acid solutions. J. Phys. Chem. 63 (1959) 808-812
6. Burrows C.J., and Muller J.G. Oxidative nucleobase modifications leading to strand scission. Chem. Rev. 98 (1998) 1109-1151
7. Buxton G.V. Radiation chemistry of the liquid state. (1) Water and homogeneous aqueous solutions. In: Farhataziz, and Rodgers M.A.J. (Eds). Radiation Chemistry, Principles and Applications (1987), VCH Publishers, New York 321-349
8. Chapman J.D., Doern S.D., Reuvers A.P., Gillespie C.J., Chatterjee A., Blakely E.A., Smith K.C., and Tobias C.A. Radioprotection by DMSO of mammalian cells exposed to X-rays and to heavy charged-particle beams. Radiat. Environ. Biophys. 16 (1979) 29-41
9. Chatterjee A., and Schaefer H.J. Microdosimetric structure of heavy ion tracks in tissue. Issue Series Title: Radiat. Environ. Biophys. 13 (1976) 215-227
10. Cooke M.S., Evans M.D., Dizdaroglu M., and Lunec J. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 17 (2003) 1195-1214
11. Douki T., Martini R., Ravanat J.-L., Turesky R.J., and Cadet J. Measurement of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 8-oxo-7,8-dihydroguanine in isolated DNA exposed to gamma radiation in aqueous solution. Carcinogenesis 18 (1997) 2385-2391
12. Fischer-Nielsen A., Jeding I.B., and Loft S. Radiation-induced formation of 8-hydroxy-2′-deoxyguanosine and its prevention by scavengers. Carcinogenesis 15 (1994) 1609-1612
13. Fuciarelli A.F., Wegher B.J., Blakely W.F., and Dizdaroglu M. Yields of radiation-induced base products in DNA: effects of DNA conformation and gassing conditions. Int. J. Radiat. Biol. 58 (1990) 397-415
14. Ito A., Nakano H., Kusano Y., Hirayama R., Furusawa Y., Murayama C., Mori T., Katsumura Y., and Shinohara K. Contribution of indirect action to radiation-induced mammalian cell inactivation: dependence on photon energy and heavy-ion LET. Radiat. Res. 165 (2006) 703-712
15. Kasai H., Tanooka H., and Nishimura S. Formation of 8-hydroxygunanine residues in DNA by X-irradiation. Gann 75 (1984) 1037-1039
16. Kasai H. Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis. Mutat. Res. 387 (1997) 147-163
17. LaVerne J.A. Radical and molecular yields in the radiolysis of water with carbon ions. Radiat. Phys. Chem. 34 (1989) 135-143
18. Roots R., Chatterjee A., Chang P., Lommel L., and Blakely E.A. Characterization of hydroxyl radical-induced damage after sparsely and densely ionizing irradiation. Int. J. Radiat. Biol. 47 (1985) 157-166
19. - and OH adducts. Chem. Rev. 89 (1989) 503-520
20. Taguchi M., and Kojima T. Yield of OH radicals in water under high-density energy deposition by heavy-ion irradiation. Radiat. Res. 163 (2005) 455-461
21. Torikoshi M., Minohara S., Kanematsu N., Komori M., Kanazawa M., Noda K., Miyahara N., Itoh H., Endo M., and Kanai T. Irradiation system for HIMAC. J. Radiat. Res. 48 Suppl. (2007) A15-A25
22. Tsujii H., Mizoe J., Kamada T., Baba M., Tsujii H., Kato H., Kato S., Yamada S., Yasuda S., Ohno T., Yanagi T., Imai R., Kagei K., Kato H., Hara R., Hasegawa A., Nakajima M., Sugane N., Tamaki N., Takagi R., Kandatsu S., Yoshikawa K., Kishimoto R., and Miyamoto T. Clinical results of carbon ion radiotherapy at NIRS. J. Radiat. Res. 48 Suppl. (2007) A1-A13
23. Yamashita S., Katsumura Y., Mingzhang L., Muroya Y., Miyazaki T., and Murakami T. Water radiolysis with heavy ions of energies up to 28 GeV. 1. Measurements of primary g values as track segment yields. Radiat. Phys. Chem. 77 (2008) 439-446