Influence of the side chain next to C-terminal benzimidazole in opioid pseudopeptides containing the Dmt-Tic pharmacophore

Journal of Medicinal Chemistry

Volumn 52, Issue 17, 2009, Pages 5556-5559

  Balboni, Gianfranco ^a   Trapella, Claudio ^b   Sasaki, Yusuke ^c   Ambo, Akihiro ^c   Marczak, Ewa D ^d   Lazarus, Lawrence H ^d   Salvadori, Severo ^b  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^d NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,4 TETRAHYDROISOQUINOLINE 3 CARBOXYLIC ACID; 2',6' DIMETHYLTYROSINE; ALANINE; ASPARTIC ACID; BENZIMIDAZOLE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DIPEPTIDE; GLUTAMIC ACID; GLYCINE; MU OPIATE RECEPTOR; OPIATE; OPIATE ANTAGONIST; PHENYLALANINE; PSEUDOPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; DRUG ACTIVITY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION; SUBSTITUTION REACTION;

ANIMALS; BENZIMIDAZOLES; DIPEPTIDES; HUMANS; INHIBITORY CONCENTRATION 50; NARCOTIC ANTAGONISTS; RECEPTORS, OPIOID; SUBSTRATE SPECIFICITY;

EID: 69949084488     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900686q     Document Type: Article

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