Understanding the structural requirements of 4-anilidopiperidine analogues for biological activities at μ and δ opioid receptors

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 8, 2007, Pages 2161-2165

  Lee, Yeon Sun ^a   Nyberg, Joel ^a   Moye, Sharif ^a   Agnes, Richard S ^a   Davis, Peg ^b   Ma, Shou wu ^b   Lai, Josephine ^b   Porreca, Frank ^b   Vardanyan, Ruben ^a   Hruby, Victor J ^b  

^a University of Arizona   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

4 Anilidopiperidine analogues; Analgesic effects; Dmt Tic; Fentanyl; Opioid receptors

Indexed keywords

DELTA OPIATE RECEPTOR; MU OPIATE RECEPTOR; PIPERIDINE DERIVATIVE;

AMINO ACID SYNTHESIS; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; DRUG ACTIVITY; DRUG STRUCTURE; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ANALGESICS; ANIMALS; CELL LINE; HUMANS; LIGANDS; MOLECULAR STRUCTURE; MUSCLE CONTRACTION; PIPERIDINES; PROTEIN BINDING; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION;

EID: 33947596846     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.01.114     Document Type: Article

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