Green tea extract selectively activates peroxisome proliferator-activated receptor β/δ in cultured cardiomyocytes

British Journal of Nutrition

Volumn 101, Issue 12, 2009, Pages 1736-1739

  Danesi, Francesca ^a   Di Nunzio, Mattia ^a   Boschetti, Elisa ^a   Bordoni, Alessandra ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Antioxidant activity; Green tea; Neonatal cardiomyocytes; Nitric oxide; Peroxisome proliferator activated receptors

Indexed keywords

FENOFIBRATE; GREEN TEA EXTRACT; NITRIC OXIDE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR DELTA; REACTIVE OXYGEN METABOLITE; ANTIOXIDANT; CATECHIN; DRUG DERIVATIVE; EPIGALLOCATECHIN GALLATE; PLANT EXTRACT;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG SELECTIVITY; HEART CELL CULTURE; HEART MUSCLE CELL; NEWBORN; NONHUMAN; RAT; ANIMAL; CELL CULTURE; CELL HYPOXIA; ENZYME ACTIVATION; ENZYMOLOGY; METABOLISM; TEA; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; ANTIOXIDANTS; CATECHIN; CELL HYPOXIA; CELLS, CULTURED; ENZYME ACTIVATION; MYOCYTES, CARDIAC; NITRIC OXIDE; PLANT EXTRACTS; PPAR DELTA; PPAR-BETA; RATS; RATS, WISTAR; TEA;

EID: 69849105712     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114508145871     Document Type: Article

References (22)

1. Tipoe GL, Leung TM, Hung MW, et al. (2007) Green tea polyphenols as an anti-oxidant and anti-inflammatory agent for cardiovascular protection. Cardiovasc Hematol Disord Drug Targets 7, 135-144.
2. Shankar S, Ganapathy S & Srivastava RK (2007) Green tea polyphenols: biology and therapeutic implications in cancer. Front Biosci 12, 4881-4899.
3. Stangl V, Dreger H, Stangl K, et al. (2007) Molecular targets of tea polyphenols in the cardiovascular system. Cardiovasc Res 73, 348-358.
4. Cook S (2006) Coronary artery disease, nitric oxide and oxidative stress: the 'Yin-Yang' effect - a Chinese concept for a worldwide pandemic. Swiss Med Wkly 136, 103-113.
5. Agnetti G, Bordoni A, Angeloni C, et al. (2005) Green tea modulation of inducible nitric oxide synthase in hypoxic/reoxygenated cardiomyocytes. Biochimie 87, 457-460.
6. Shay NF & Banz WJ (2005) Regulation of gene transcription by botanicals: novel regulatory mechanisms. Annu Rev Nutr 25, 297-315.
7. Paukkeri EL, Leppanen T, Sareila O, et al. (2007) PPARa agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages. Br J Pharmacol 152, 1081-1091.
8. Bordoni A, Hrelia S, Angeloni C, et al. (2002) Green tea protection of hypoxia/reoxygenation injury in cultured cardiac cells. J Nutr Biochem 13, 103-111.
9. Balligand JL, Ungureanu-Longrois D, Simmons WW, et al. (1995) Induction of NO synthase in rat cardiac microvascular endothelial cells by IL-1b and IFN-g. Am J Physiol 268, H1293-H1303.
10. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248-254.
11. Wright G, Singh IS, Hasday JD, et al. (2002) Endotoxin stressresponse in cardiomyocytes: NF-kB activation and tumor necrosis factor-a expression. Am J Physiol Heart Circ Physiol 282, H872-H879.
12. Re R, Pellegrini N, Proteggente A, et al. (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biol Med 26, 1231-1237.
13. Wei L & Zhu H (1996) The influence of hypoxia/reoxygenation on production and release of nitric oxide from cultured newborn rat cardiomyocytes. Zhonghua Yi Xue Za Zhi 76, 697-699.
14. D'Archivio M, Santangelo C, Scazzocchio B, et al. (2008) Modulatory effects of polyphenols on apoptosis induction: relevance for cancer prevention. Int J Mol Sci 9, 213-228.
15. Takano H, Nagai T, Asakawa M, et al. (2000) Peroxisome proliferator-activated receptor activators inhibit lipopolysaccharide- induced tumor necrosis factor-a expression in neonatal rat cardiac myocytes. Circ Res 87, 596-602.
16. Planavila A, Rodriguez-Calvo R, Jove M, et al. (2005) Peroxisome proliferator-activated receptor b/d activation inhibits hypertrophy in neonatal rat cardiomyocytes. Cardiovasc Res 65, 832-841.
17. Bayon Y, Ortiz MA, Lopez-Hernandez FJ, et al. (2003) Inhibition of IkB kinase by a new class of retinoid-related anticancer agents that induce apoptosis. Mol Cell Biol 23, 1061-1074.
18. Nam S, Smith DM & Dou QP (2001) Ester bond-containing tea polyphenols potently inhibit proteasome activity in vitro and in vivo. J Biol Chem 276, 13322-13330.
19. Hauser S, Adelmant G, Sarraf P, et al. (2000) Degradation of the peroxisome proliferator-activated receptor g is linked to ligand-dependent activation. J Biol Chem 275, 18527-18533. (Pubitemid 30414814)
20. Jugdutt BI (2002) Nitric oxide and cardioprotection during ischemia-reperfusion. Heart Fail Rev 7, 391-405.
21. Sheng L, Ye P, Liu YX, et al. (2008) Peroxisome proliferatoractivated receptor b/d activation improves angiotensin II-induced cardiac hypertrophy in vitro. Clin Exp Hypertens 30, 109-119.
22. Lee K (2004) Transactivation of peroxisome proliferator-activated receptor a by green tea extracts. J Vet Sci 4, 325-330.