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Volumn 67, Issue 7, 2009, Pages 251-259

CD20-targeted therapy: A breakthrough in the treatment of non-Hodgkin's lymphoma

Author keywords

Anti CD20 therapy; CD20; Non Hodgkin's lymphoma; Rituximab

Indexed keywords

AME 133; ANTIINFECTIVE AGENT; CD20 ANTIGEN; GA 101; IMMU 106; LY 2469298; OCRELIZUMAB; OFATUMUMAB; PRO 131921; RITUXIMAB; RO 5072759; TOSITUMOMAB; UNCLASSIFIED DRUG; VELTUZUMAB;

EID: 69849104453     PISSN: 03002977     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (52)

References (81)
  • 1
    • 0018949401 scopus 로고
    • Characterization of a human B lymphocyte-specific antigen
    • Stashenko P, Nadler LM, Hardy R, Schlossman SF. Characterization of a human B lymphocyte-specific antigen. J Immunol. 1980;125(4):1678-1685
    • (1980) J Immunol , vol.125 , Issue.4 , pp. 1678-1685
    • Stashenko, P.1    Nadler, L.M.2    Hardy, R.3    Schlossman, S.F.4
  • 3
    • 0021203714 scopus 로고
    • B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation
    • Nadler LM, Korsmeyer SJ, Anderson KC, et al. B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation. J Clin Invest. 1984;74(2):332-340
    • (1984) J Clin Invest , vol.74 , Issue.2 , pp. 332-340
    • Nadler, L.M.1    Korsmeyer, S.J.2    Anderson, K.C.3
  • 4
    • 0021272605 scopus 로고
    • Expression of human B cell-associated antigens on leukemias and lymphomas: A model of human B cell differentiation
    • Anderson KC, Bates MP, Slaughenhoupt BL, Pinkus GS, Schlossman SF, Nadler LM. Expression of human B cell-associated antigens on leukemias and lymphomas: a model of human B cell differentiation. Blood. 1984;63(6):1424-1433
    • (1984) Blood , vol.63 , Issue.6 , pp. 1424-1433
    • Anderson, K.C.1    Bates, M.P.2    Slaughenhoupt, B.L.3    Pinkus, G.S.4    Schlossman, S.F.5    Nadler, L.M.6
  • 5
    • 0023976470 scopus 로고
    • Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains
    • Einfeld DA, Brown JP, Valentine MA, Clark EA, Ledbetter JA. Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains. EMBO J. 1988;7(3):711-717
    • (1988) EMBO J , vol.7 , Issue.3 , pp. 711-717
    • Einfeld, D.A.1    Brown, J.P.2    Valentine, M.A.3    Clark, E.A.4    Ledbetter, J.A.5
  • 6
    • 0023101978 scopus 로고
    • Monoclonal antibody 1F5 (anti-CD20) serotherapy of human B cell lymphomas
    • Press OW, Appelbaum F, Ledbetter JA, et al. Monoclonal antibody 1F5 (anti-CD20) serotherapy of human B cell lymphomas. Blood. 1987;69(2):584-591 (Pubitemid 17022032)
    • (1987) Blood , vol.69 , Issue.2 , pp. 584-591
    • Press, O.W.1    Appelbaum, F.2    Ledbetter, J.A.3
  • 7
    • 0036408912 scopus 로고    scopus 로고
    • CD20-mediated apoptosis: Signalling through lipid rafts
    • DOI 10.1046/j.1365-2567.2002.01495.x
    • Deans JP, Li H, Polyak MJ. CD20-mediated apoptosis: signalling through lipid rafts. Immunology. 2002;107(2):176-182 (Pubitemid 35279043)
    • (2002) Immunology , vol.107 , Issue.2 , pp. 176-182
    • Deans, J.P.1    Li, H.2    Polyak, M.J.3
  • 8
    • 0036566507 scopus 로고    scopus 로고
    • Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure
    • Polyak MJ, Deans JP. Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure. Blood. 2002;99(9):3256-3262
    • (2002) Blood , vol.99 , Issue.9 , pp. 3256-3262
    • Polyak, M.J.1    Deans, J.P.2
  • 9
    • 1642306050 scopus 로고    scopus 로고
    • Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents
    • Cragg MS, Glennie MJ. Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents. Blood. 2004;103(7):2738-2743
    • (2004) Blood , vol.103 , Issue.7 , pp. 2738-2743
    • Cragg, M.S.1    Glennie, M.J.2
  • 10
    • 33745324686 scopus 로고    scopus 로고
    • The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20
    • Teeling JL, Mackus WJ, Wiegman LJ, et al. The biological activity of human CD20 monoclonal antibodies is linked to unique epitopes on CD20. J Immunol. 2006;177(1):362-371
    • (2006) J Immunol , vol.177 , Issue.1 , pp. 362-371
    • Teeling, J.L.1    Mackus, W.J.2    Wiegman, L.J.3
  • 11
    • 7244248664 scopus 로고    scopus 로고
    • From the bench to the bedside: Ways to improve rituximab efficacy
    • DOI 10.1182/blood-2004-03-1110
    • Cartron G, Watier H, Golay J, Solal-Celigny P. From the bench to the bedside: ways to improve rituximab efficacy. Blood. 2004;104(9):2635-2642 (Pubitemid 39434941)
    • (2004) Blood , vol.104 , Issue.9 , pp. 2635-2642
    • Cartron, G.1    Watier, H.2    Golay, J.3    Solal-Celigny, P.4
  • 12
    • 47749135829 scopus 로고    scopus 로고
    • Induction of cytosolic calcium flux by CD20 is dependent upon B Cell antigen receptor signaling
    • Walshe CA, Beers SA, French RR, et al. Induction of cytosolic calcium flux by CD20 is dependent upon B Cell antigen receptor signaling. J Biol Chem. 2008;283(25):16971-16984
    • (2008) J Biol Chem , vol.283 , Issue.25 , pp. 16971-16984
    • Walshe, C.A.1    Beers, S.A.2    French, R.R.3
  • 15
    • 0037306893 scopus 로고    scopus 로고
    • In vitro mechanisms of action of rituximab on primary non-Hodgkin lymphomas
    • Manches O, Lui G, Chaperot L, et al. In vitro mechanisms of action of rituximab on primary non-Hodgkin lymphomas. Blood. 2003;101(3):949-954
    • (2003) Blood , vol.101 , Issue.3 , pp. 949-954
    • Manches, O.1    Lui, G.2    Chaperot, L.3
  • 16
    • 0036464611 scopus 로고    scopus 로고
    • The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: Evidence of caspase activation and apoptosis induction
    • DOI 10.1182/blood.V99.3.1038
    • Byrd JC, Kitada S, Flinn IW, et al. The mechanism of tumor cell clearance by rituximab in vivo in patients with B-cell chronic lymphocytic leukemia: evidence of caspase activation and apoptosis induction. Blood. 2002;99(3):1038-1043 (Pubitemid 34525569)
    • (2002) Blood , vol.99 , Issue.3 , pp. 1038-1043
    • Byrd, J.C.1    Kitada, S.2    Flinn, I.W.3    Aron, J.L.4    Pearson, M.5    Lucas, D.6    Reed, J.C.7
  • 19
    • 0037306946 scopus 로고    scopus 로고
    • Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts
    • Cragg MS, Morgan SM, Chan HT, et al. Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts. Blood. 2003;101(3):1045-1052
    • (2003) Blood , vol.101 , Issue.3 , pp. 1045-1052
    • Cragg, M.S.1    Morgan, S.M.2    Chan, H.T.3
  • 20
    • 0034660092 scopus 로고    scopus 로고
    • Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis
    • Golay J, Zaffaroni L, Vaccari T, et al. Biologic response of B lymphoma cells to anti-CD20 monoclonal antibody rituximab in vitro: CD55 and CD59 regulate complement-mediated cell lysis. Blood. 2000;95(12):3900-3908 (Pubitemid 30412866)
    • (2000) Blood , vol.95 , Issue.12 , pp. 3900-3908
    • Golay, J.1    Zaffaroni, L.2    Vaccari, T.3    Lazzari, M.4    Borleri, G.-M.5    Bernasconi, S.6    Tedesco, F.7    Rambaldi, A.8    Introna, M.9
  • 21
    • 0035469885 scopus 로고    scopus 로고
    • Expression of complement inhibitors CD46, CD55, and CD59 on tumor cells does not predict clinical outcome after rituximab treatment in follicular non-Hodgkin lymphoma
    • Weng WK, Levy R. Expression of complement inhibitors CD46, CD55, and CD59 on tumor cells does not predict clinical outcome after rituximab treatment in follicular non-Hodgkin lymphoma. Blood. 2001;98(5):1352-1357
    • (2001) Blood , vol.98 , Issue.5 , pp. 1352-1357
    • Weng, W.K.1    Levy, R.2
  • 22
    • 0035525769 scopus 로고    scopus 로고
    • Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species
    • Bellosillo B, Villamor N, Lopez-Guillermo A, et al. Complement-mediated cell death induced by rituximab in B-cell lymphoproliferative disorders is mediated in vitro by a caspase-independent mechanism involving the generation of reactive oxygen species. Blood. 2001;98(9):2771-2777
    • (2001) Blood , vol.98 , Issue.9 , pp. 2771-2777
    • Bellosillo, B.1    Villamor, N.2    Lopez-Guillermo, A.3
  • 23
    • 0035760902 scopus 로고    scopus 로고
    • CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: Further regulation by CD55 and CD59
    • Golay J, Lazzari M, Facchinetti V, et al. CD20 levels determine the in vitro susceptibility to rituximab and complement of B-cell chronic lymphocytic leukemia: further regulation by CD55 and CD59. Blood. 2001;98(12):3383-3389
    • (2001) Blood , vol.98 , Issue.12 , pp. 3383-3389
    • Golay, J.1    Lazzari, M.2    Facchinetti, V.3
  • 24
    • 0034091481 scopus 로고    scopus 로고
    • Rituximab (anti-CD20) therapy of B-cell lymphomas: Direct complement killing is superior to cellular effector mechanisms
    • DOI 10.1046/j.1365-3083.2000.00745.x
    • Harjunpaa A, Junnikkala S, Meri S. Rituximab (anti-CD20) therapy of B-cell lymphomas: direct complement killing is superior to cellular effector mechanisms. Scand J Immunol. 2000;51(6):634-641 (Pubitemid 30353375)
    • (2000) Scandinavian Journal of Immunology , vol.51 , Issue.6 , pp. 634-641
    • Harjunpaa, A.1    Junnikkala, S.2    Meri, S.3
  • 25
    • 3042743884 scopus 로고    scopus 로고
    • Rituximab-dependent cytotoxicity by natural killer cells: Influence of FCGR3A polymorphism on the concentration-effect relationship
    • DOI 10.1158/0008-5472.CAN-03-2862
    • Dall'Ozzo S, Tartas S, Paintaud G, et al. Rituximab-dependent cytotoxicity by natural killer cells: influence of FCGR3A polymorphism on the concentration-effect relationship. Cancer Res. 2004;64(13):4664-4669 (Pubitemid 38856941)
    • (2004) Cancer Research , vol.64 , Issue.13 , pp. 4664-4669
    • Dall'Ozzo, S.1    Tartas, S.2    Paintaud, G.3    Cartron, G.4    Colombat, P.5    Bardos, P.6    Watier, H.7    Thibault, G.8
  • 26
    • 0036464719 scopus 로고    scopus 로고
    • Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene
    • DOI 10.1182/blood.V99.3.754
    • Cartron G, Dacheux L, Salles G, et al. Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood. 2002;99(3):754-758 (Pubitemid 34525533)
    • (2002) Blood , vol.99 , Issue.3 , pp. 754-758
    • Cartron, G.1    Dacheux, L.2    Salles, G.3    Solal-Celigny, P.4    Bardos, P.5    Colombat, P.6    Watier, H.7
  • 27
    • 3042592452 scopus 로고    scopus 로고
    • The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy
    • DOI 10.1084/jem.20040119
    • Uchida J, Hamaguchi Y, Oliver JA, et al. The innate mononuclear phagocyte network depletes B lymphocytes through Fc receptor-dependent mechanisms during anti-CD20 antibody immunotherapy. J Exp Med. 2004;199(12):1659-1669 (Pubitemid 38821999)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.12 , pp. 1659-1669
    • Uchida, J.1    Hamaguchi, Y.2    Oliver, J.A.3    Ravetch, J.V.4    Poe, J.C.5    Haas, K.M.6    Tedder, T.F.7
  • 28
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • DOI 10.1038/74704
    • Clynes RA, Towers TL, Presta LG, Ravetch JV. Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med. 2000;6(4):443-446 (Pubitemid 30208162)
    • (2000) Nature Medicine , vol.6 , Issue.4 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 31
    • 1342282157 scopus 로고    scopus 로고
    • Rituximab infusion promotes rapid complement depletion and acute CD20 loss in chronic lymphocytic leukemia
    • Kennedy AD, Beum PV, Solga MD, et al. Rituximab infusion promotes rapid complement depletion and acute CD20 loss in chronic lymphocytic leukemia. J Immunol. 2004;172(5):3280-3288
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 3280-3288
    • Kennedy, A.D.1    Beum, P.V.2    Solga, M.D.3
  • 33
    • 0030611643 scopus 로고    scopus 로고
    • Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype
    • Koene HR, Kleijer M, Algra J, Roos D, von dem Borne AE, de Haas M. Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype. Blood. 1997;90(3):1109-1114
    • (1997) Blood , vol.90 , Issue.3 , pp. 1109-1114
    • Koene, H.R.1    Kleijer, M.2    Algra, J.3    Roos, D.4    Von Dem Borne, A.E.5    De Haas, M.6
  • 35
    • 0028127304 scopus 로고
    • Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma
    • Maloney DG, Liles TM, Czerwinski DK, et al. Phase I clinical trial using escalating single-dose infusion of chimeric anti-CD20 monoclonal antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma. Blood. 1994;84(8):2457-2466
    • (1994) Blood , vol.84 , Issue.8 , pp. 2457-2466
    • Maloney, D.G.1    Liles, T.M.2    Czerwinski, D.K.3
  • 36
    • 0032740187 scopus 로고    scopus 로고
    • Overview of the clinical development of rituximab: First monoclonal antibody approved for the treatment of lymphoma
    • Grillo-Lopez AJ, White CA, Varns C, et al. Overview of the clinical development of rituximab: first monoclonal antibody approved for the treatment of lymphoma. Semin Oncol. 1999;26(5 Suppl 14):66-73. (Pubitemid 29523413)
    • (1999) Seminars in Oncology , vol.26 , Issue.5 SUPPL. 14 , pp. 66-73
    • Grillo-Lopez, A.J.1    White, C.A.2    Varns, C.3    Shen, D.4    Wei, A.5    McClure, A.6    Dallaire, B.K.7
  • 38
    • 8744274334 scopus 로고    scopus 로고
    • The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: Results of a prospective randomized study of the German Low-Grade Lymphoma Study Group
    • DOI 10.1182/blood-2004-04-1323
    • Forstpointner R, Dreyling M, Repp R, et al. The addition of rituximab to a combination of fludarabine, cyclophosphamide, mitoxantrone (FCM) significantly increases the response rate and prolongs survival as compared with FCM alone in patients with relapsed and refractory follicular and mantle cell lymphomas: results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood. 2004;104(10):3064-3071 (Pubitemid 39517009)
    • (2004) Blood , vol.104 , Issue.10 , pp. 3064-3071
    • Forstpointner, R.1    Dreyling, M.2    Repp, R.3    Hermann, S.4    Hanel, A.5    Metzner, B.6    Pott, C.7    Hartmann, F.8    Rothmann, F.9    Rohrberg, R.10    Bock, H.-P.11    Wandt, H.12    Unterhalt, M.13    Hiddemann, W.14
  • 43
    • 53749085410 scopus 로고    scopus 로고
    • Phase III study of R-CVP compared with cyclophosphamide, vincristine, and prednisone alone in patients with previously untreated advanced follicular lymphoma
    • Marcus R, Imrie K, Solal-Celigny P, et al. Phase III study of R-CVP compared with cyclophosphamide, vincristine, and prednisone alone in patients with previously untreated advanced follicular lymphoma. J Clin Oncol. 2008;26(28):4579-4586
    • (2008) J Clin Oncol , vol.26 , Issue.28 , pp. 4579-4586
    • Marcus, R.1    Imrie, K.2    Solal-Celigny, P.3
  • 44
    • 33646004738 scopus 로고    scopus 로고
    • CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: A randomised controlled trial by the MabThera International Trial (MInT) Group
    • Pfreundschuh M, Trumper L, Osterborg A, et al. CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large-B-cell lymphoma: a randomised controlled trial by the MabThera International Trial (MInT) Group. Lancet Oncol. 2006;7(5):379-391
    • (2006) Lancet Oncol , vol.7 , Issue.5 , pp. 379-391
    • Pfreundschuh, M.1    Trumper, L.2    Osterborg, A.3
  • 45
    • 58149386408 scopus 로고    scopus 로고
    • Rituximab combined with chemotherapy and interferon in follicular lymphoma patients: Results of the GELA-GOELAMS FL2000 study
    • Salles G, Mounier N, de Guibert S, et al. Rituximab combined with chemotherapy and interferon in follicular lymphoma patients: results of the GELA-GOELAMS FL2000 study. Blood. 2008;112(13):4824-4831
    • (2008) Blood , vol.112 , Issue.13 , pp. 4824-4831
    • Salles, G.1    Mounier, N.2    De Guibert, S.3
  • 47
    • 14544276412 scopus 로고    scopus 로고
    • Maximizing therapeutic benefit of rituximab: Maintenance therapy versus re-treatment at progression in patients with indolent non-Hodgkin's lymphoma - A randomized phase II trial of the Minnie Pearl Cancer Research Network
    • DOI 10.1200/JCO.2005.12.191
    • Hainsworth JD, Litchy S, Shaffer DW, Lackey VL, Grimaldi M, Greco FA. Maximizing therapeutic benefit of rituximab: maintenance therapy versus re-treatment at progression in patients with indolent non-Hodgkin's lymphoma - a randomized phase II trial of the Minnie Pearl Cancer Research Network. J Clin Oncol. 2005;23(6):1088-1095 (Pubitemid 46202263)
    • (2005) Journal of Clinical Oncology , vol.23 , Issue.6 , pp. 1088-1095
    • Hainsworth, J.D.1    Litchy, S.2    Shaffer, D.W.3    Van Lackey, L.4    Grimaldi, M.5    Greco, F.A.6
  • 48
    • 33845574852 scopus 로고    scopus 로고
    • The therapeutic use of rituximab in non-Hodgkin's lymphoma
    • DOI 10.1111/j.1600-0609.2006.00789.x
    • Marcus R, Hagenbeek A. The therapeutic use of rituximab in non-Hodgkin's lymphoma. Eur J Haematol Suppl. 2007;(67):5-14. (Pubitemid 44934857)
    • (2007) European Journal of Haematology , vol.78 , Issue.SUPPL. 67 , pp. 5-14
    • Marcus, R.1    Hagenbeek, A.2
  • 49
    • 63749107163 scopus 로고    scopus 로고
    • Maintenance or Eradication of Residual Disease in Indolent Lymphoma: Where Do We Stand?
    • Editorial
    • Hagenbeek A. Maintenance or Eradication of Residual Disease in Indolent Lymphoma: Where Do We Stand? (Editorial) J Clin Oncol. 2009;27(10):1540-1542
    • (2009) J Clin Oncol , vol.27 , Issue.10 , pp. 1540-1542
    • Hagenbeek, A.1
  • 50
    • 63749097149 scopus 로고    scopus 로고
    • Maintenance Rituximab after Cyclophosphamide, Vincristine, and Prednisone Prolongs Progression-Free Survival in Advanced Indolent Lymphoma: Results of the Randomized Phase III ECOG1496 Study
    • Hochster H, Weller E, Gascoyne RD, et al. Maintenance Rituximab After Cyclophosphamide, Vincristine, and Prednisone Prolongs Progression-Free Survival in Advanced Indolent Lymphoma: Results of the Randomized Phase III ECOG1496 Study. J Clin Oncol. 2009;27(10):1607-1614
    • (2009) J Clin Oncol , vol.27 , Issue.10 , pp. 1607-1614
    • Hochster, H.1    Weller, E.2    Gascoyne, R.D.3
  • 51
    • 33745662565 scopus 로고    scopus 로고
    • B cells move to centre stage: Novel opportunities for autoimmune disease treatment
    • Browning JL. B cells move to centre stage: novel opportunities for autoimmune disease treatment. Nat Rev Drug Discov. 2006;5(7):564-576
    • (2006) Nat Rev Drug Discov , vol.5 , Issue.7 , pp. 564-576
    • Browning, J.L.1
  • 52
    • 33847068351 scopus 로고    scopus 로고
    • Drug insight: The mechanism of action of rituximab in autoimmune disease - The immune complex decoy hypothesis
    • Taylor RP, Lindorfer MA. Drug insight: the mechanism of action of rituximab in autoimmune disease - the immune complex decoy hypothesis. Nat Clin Pract Rheumatol. 2007;3(2):86-95.
    • (2007) Nat Clin Pract Rheumatol , vol.3 , Issue.2 , pp. 86-95
    • Taylor, R.P.1    Lindorfer, M.A.2
  • 53
    • 33646362290 scopus 로고    scopus 로고
    • B-cell targeting in rheumatoid arthritis and other autoimmune diseases
    • Edwards JC, Cambridge G. B-cell targeting in rheumatoid arthritis and other autoimmune diseases. Nat Rev Immunol. 2006;6(5):394-403.
    • (2006) Nat Rev Immunol , vol.6 , Issue.5 , pp. 394-403
    • Edwards, J.C.1    Cambridge, G.2
  • 55
    • 4944225787 scopus 로고    scopus 로고
    • Anti-CD20 monoclonal antibody treatment in 6 patients with therapy-refractory chronic graft-versus-host disease
    • DOI 10.1182/blood-2004-05-1855
    • Canninga-van Dijk MR, van der Straaten HM, Fijnheer R, Sanders CJ, van den Tweel JG, Verdonck LF. Anti-CD20 monoclonal antibody treatment in 6 patients with therapy-refractory chronic graft-versus-host disease. Blood. 2004;104(8):2603-2606 (Pubitemid 39331867)
    • (2004) Blood , vol.104 , Issue.8 , pp. 2603-2606
    • Canninga-Van Dijk, M.R.1    Van Der Straaten, H.M.2    Fijnheer, R.3    Sanders, C.J.4    Van Den Tweel, J.G.5    Verdonck, L.F.6
  • 57
    • 33947675243 scopus 로고    scopus 로고
    • Rituximab is effective for extensive steroid-refractory chronic graft-vs.-host-disease [3]
    • DOI 10.1080/10428190601094362, PII 773541161
    • Carella AM, Biasco S, Nati S, Congiu A, Lerma E. Rituximab is effective for extensive steroid-refractory chronic graft-vs.-host-disease. Leuk Lymphoma. 2007;48(3):623-624 (Pubitemid 46487774)
    • (2007) Leukemia and Lymphoma , vol.48 , Issue.3 , pp. 623-624
    • Carella, A.M.1    Biasco, S.2    Nati, S.3    Congiu, A.4    Lerma, E.5
  • 60
    • 16444363534 scopus 로고    scopus 로고
    • Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma: Implications in chemosensitization and therapeutic intervention
    • DOI 10.1038/sj.onc.1208349
    • Jazirehi AR, Bonavida B. Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma: implications in chemosensitization and therapeutic intervention. Oncogene. 2005;24(13):2121-2143 (Pubitemid 40516580)
    • (2005) Oncogene , vol.24 , Issue.13 , pp. 2121-2143
    • Jazirehi, A.R.1    Bonavida, B.2
  • 61
    • 0034671944 scopus 로고    scopus 로고
    • CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms
    • Askew D, Chu RS, Krieg AM, Harding CV. CpG DNA induces maturation of dendritic cells with distinct effects on nascent and recycling MHC-II antigen-processing mechanisms. J Immunol. 2000;165(12):6889-6895 (Pubitemid 32001158)
    • (2000) Journal of Immunology , vol.165 , Issue.12 , pp. 6889-6895
    • Askew, D.1    Chu, R.S.2    Krieg, A.M.3    Harding, C.V.4
  • 63
    • 0036226045 scopus 로고    scopus 로고
    • Activation of the immune system by bacterial CpG-DNA
    • DOI 10.1046/j.0019-2805.2001.01350.x
    • Hacker G, Redecke V, Hacker H. Activation of the immune system by bacterial CpG-DNA. Immunology 2002;105(3):245-251 (Pubitemid 34304400)
    • (2002) Immunology , vol.105 , Issue.3 , pp. 245-251
    • Hacker, G.1    Redecke, V.2    Hacker, H.3
  • 64
    • 4444343395 scopus 로고    scopus 로고
    • Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas
    • Teeling JL, French RR, Cragg MS, et al. Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas. Blood. 2004;104(6):1793-1800
    • (2004) Blood , vol.104 , Issue.6 , pp. 1793-1800
    • Teeling, J.L.1    French, R.R.2    Cragg, M.S.3
  • 66
    • 47049124865 scopus 로고    scopus 로고
    • First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: Results of a phase I/II trial
    • Hagenbeek A, Gadeberg O, Johnson P, et al. First clinical use of ofatumumab, a novel fully human anti-CD20 monoclonal antibody in relapsed or refractory follicular lymphoma: results of a phase I/II trial. Blood. 2008;111(12):5486-5495
    • (2008) Blood , vol.111 , Issue.12 , pp. 5486-5495
    • Hagenbeek, A.1    Gadeberg, O.2    Johnson, P.3
  • 67
    • 48249127022 scopus 로고    scopus 로고
    • Interim Results of a Phase I/II Study of Ocrelizumab, a New Humanised Anti-CD20 Antibody in Patients with Relapsed/Refractory Follicular Non-Hodgkin's Lymphoma
    • Morschhauser F, Marlton P, Vitolo U, et al. Interim Results of a Phase I/II Study of Ocrelizumab, a New Humanised Anti-CD20 Antibody in Patients with Relapsed/Refractory Follicular Non-Hodgkin's Lymphoma. ASH Annual Meeting Abstracts 2007;110(11):645.
    • (2007) ASH Annual Meeting Abstracts , vol.110 , Issue.11 , pp. 645
    • Morschhauser, F.1    Marlton, P.2    Vitolo, U.3
  • 68
    • 51849148443 scopus 로고    scopus 로고
    • Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study
    • Genovese MC, Kaine JL, Lowenstein MB, et al. Ocrelizumab, a humanized anti-CD20 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I/II randomized, blinded, placebo-controlled, dose-ranging study. Arthritis Rheum. 2008;58(9):2652-2661
    • (2008) Arthritis Rheum , vol.58 , Issue.9 , pp. 2652-2661
    • Genovese, M.C.1    Kaine, J.L.2    Lowenstein, M.B.3
  • 70
    • 60849089338 scopus 로고    scopus 로고
    • Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody
    • Goldenberg DM, Rossi EA, Stein R, et al. Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody. Blood. 2009;113(5):1062-1070
    • (2009) Blood , vol.113 , Issue.5 , pp. 1062-1070
    • Goldenberg, D.M.1    Rossi, E.A.2    Stein, R.3
  • 71
    • 1942502328 scopus 로고    scopus 로고
    • Characterization of a New Humanized Anti-CD20 Monoclonal Antibody, IMMU-106, and Its Use in Combination with the Humanized Anti-CD22 Antibody, Epratuzumab, for the Therapy of Non-Hodgkin's Lymphoma
    • DOI 10.1158/1078-0432.CCR-03-0493
    • Stein R, Qu Z, Chen S, et al. Characterization of a new humanized anti-CD20 monoclonal antibody, IMMU-106, and its use in combination with the humanized anti-CD22 antibody, epratuzumab, for the therapy of non-Hodgkin's lymphoma. Clin Cancer Res. 2004;10(8):2868-2878 (Pubitemid 38509167)
    • (2004) Clinical Cancer Research , vol.10 , Issue.8 , pp. 2868-2878
    • Stein, R.1    Qu, Z.2    Chen, S.3    Rosario, A.4    Shi, V.5    Hayes, M.6    Horak, I.D.7    Hansen, H.J.8    Goldenberg, D.M.9
  • 72
    • 33748297773 scopus 로고    scopus 로고
    • Initial safety and efficacy results of a second-generation humanized anti-CD20 antibody, IMMU-106 (hA20), in Non-Hodgkin's Lymphoma
    • Morschhauser F, Leonard JP, Coiffier B, et al. Initial safety and efficacy results of a second-generation humanized anti-CD20 antibody, IMMU-106 (hA20), in Non-Hodgkin's Lymphoma. ASH Annual Meeting Abstracts. 2005;106(11):2428.
    • (2005) ASH Annual Meeting Abstracts , vol.106 , Issue.11 , pp. 2428
    • Morschhauser, F.1    Leonard, J.P.2    Coiffier, B.3
  • 73
    • 34948852209 scopus 로고    scopus 로고
    • Phase I/II results of a second-generation humanized anti-CD20 antibody, IMMU-106 (hA20), in NHL
    • Morshhauser F, Leonard JP, Coiffier B, et al. Phase I/II results of a second-generation humanized anti-CD20 antibody, IMMU-106 (hA20), in NHL. J Clin Oncol. (Meeting Abstracts). 2006;24(18 suppl):7530.
    • (2006) J Clin Oncol. (Meeting Abstracts) , vol.24 , Issue.18 , pp. 7530
    • Morshhauser, F.1    Leonard, J.P.2    Coiffier, B.3
  • 74
    • 34548525578 scopus 로고    scopus 로고
    • Low doses of humanized anti-CD20 antibody, IMMU-106 (hA20), in refractory or recurrent NHL: Phase I/II results
    • Morschhauser F, Leonard JP, Fayad L, et al. Low doses of humanized anti-CD20 antibody, IMMU-106 (hA20), in refractory or recurrent NHL: Phase I/II results. J Clin Oncol. (Meeting Abstracts) 2007;25(18 suppl):8032.
    • (2007) J Clin Oncol. (Meeting Abstracts) , vol.25 , Issue.18 SUPPL. , pp. 8032
    • Morschhauser, F.1    Leonard, J.P.2    Fayad, L.3
  • 75
    • 41249102744 scopus 로고    scopus 로고
    • Anti-CD20 monoclonal antibody (mAb) with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab (R)
    • Weiner G, Bowles J, Link B, Campbell M, Wooldridge J, Breitmeyer J. Anti-CD20 monoclonal antibody (mAb) with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab (R). ASH Annual Meeting Abstracts. 2005;106(11):348.
    • (2005) ASH Annual Meeting Abstracts , vol.106 , Issue.11 , pp. 348
    • Weiner, G.1    Bowles, J.2    Link, B.3    Campbell, M.4    Wooldridge, J.5    Breitmeyer, J.6
  • 76
    • 33750622479 scopus 로고    scopus 로고
    • Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab
    • Bowles JA, Wang SY, Link BK, et al. Anti-CD20 monoclonal antibody with enhanced affinity for CD16 activates NK cells at lower concentrations and more effectively than rituximab. Blood. 2006;108(8):2648-2654
    • (2006) Blood , vol.108 , Issue.8 , pp. 2648-2654
    • Bowles, J.A.1    Wang, S.Y.2    Link, B.K.3
  • 77
    • 65449177689 scopus 로고    scopus 로고
    • A re-examination of radioimmunotherapy in the treatment of non-Hodgkin lymphoma: Prospects for dual-targeted antibody/radioantibody therapy
    • Epub ahead of print
    • Sharkey RM, Press OW, Goldenberg DM. A re-examination of radioimmunotherapy in the treatment of non-Hodgkin lymphoma: Prospects for dual-targeted antibody/radioantibody therapy. Blood. 2009, Epub ahead of print.
    • (2009) Blood
    • Sharkey, R.M.1    Press, O.W.2    Goldenberg, D.M.3
  • 78
    • 58149162030 scopus 로고    scopus 로고
    • Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation
    • Beers SA, Chan CH, James S, et al. Type II (tositumomab) anti-CD20 monoclonal antibody out performs type I (rituximab-like) reagents in B-cell depletion regardless of complement activation. Blood. 2008;112(10):4170-4177
    • (2008) Blood , vol.112 , Issue.10 , pp. 4170-4177
    • Beers, S.A.1    Chan, Ch.2    James, S.3
  • 79
    • 34548386910 scopus 로고    scopus 로고
    • Novel 3rd Generation Humanized type II CD20 antibody with glycoengineered Fc and modified elbow hinge for enhanced ADCC and superior apoptosis induction
    • Umana P, Moessner E, Bruenker P, et al. Novel 3rd Generation Humanized type II CD20 antibody with glycoengineered Fc and modified elbow hinge for enhanced ADCC and superior apoptosis induction. ASH Annual Meeting Abstracts. 2006;108(11):229.
    • (2006) ASH Annual Meeting Abstracts , vol.108 , Issue.11 , pp. 229
    • Umana, P.1    Moessner, E.2    Bruenker, P.3
  • 80
    • 33646070900 scopus 로고    scopus 로고
    • Modulation of therapeutic antibody effector functions by glycosylation engineering: Influence of Golgi enzyme localization domain and co-expression of heterologous beta1, 4-N-acetylglucosaminyltransferase III and Golgi alpha-mannosidase II
    • Ferrara C, Brunker P, Suter T, Moser S, Puntener U, Umana P. Modulation of therapeutic antibody effector functions by glycosylation engineering: influence of Golgi enzyme localization domain and co-expression of heterologous beta1, 4-N-acetylglucosaminyltransferase III and Golgi alpha-mannosidase II. Biotechnol Bioeng. 2006;93(5):851-861
    • (2006) Biotechnol Bioeng , vol.93 , Issue.5 , pp. 851-861
    • Ferrara, C.1    Brunker, P.2    Suter, T.3    Moser, S.4    Puntener, U.5    Umana, P.6
  • 81
    • 67649575638 scopus 로고    scopus 로고
    • A Phase I/II Study of RO5072759 (GA101) in Patients with Relapsed/Refractory CD20+ Malignant Disease
    • Salles G, Morschhauser F, Cartron G, et al. A Phase I/II Study of RO5072759 (GA101) in Patients with Relapsed/Refractory CD20+ Malignant Disease. ASH Annual Meeting Abstracts. 2008;112(11):234.
    • (2008) ASH Annual Meeting Abstracts , vol.112 , Issue.11 , pp. 234
    • Salles, G.1    Morschhauser, F.2    Cartron, G.3


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