Cross-linked carrageenan beads for controlled release delivery systems

Carbohydrate Polymers

Volumn 78, Issue 4, 2009, Pages 973-977

  Keppeler, S ^a   Ellis, A ^a   Jacquier, J C ^a  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Carrageenan beads; Cross linking; Microspheres; Salt responsiveness; Swelling behaviour

Indexed keywords

BEAD SIZE; CARRAGEENAN BEADS; CARRAGEENANS; CONTROLLED RELEASE; CROSS-LINK DENSITIES; CROSSLINKER; DELIVERY SYSTEMS; EPICHLOROHYDRIN; GEL BEADS; MACRO-PARTICLES; MICRO-GELS; MICRO-PARTICLES; PHARMACEUTICAL PRODUCTS; SALINE SOLUTIONS; SWELLING BEHAVIOUR;

GELATION; POLYSACCHARIDES; SURFACE TOPOGRAPHY;

MICROSPHERES;

EID: 69749091453     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2009.07.029     Document Type: Article

References (19)

1. Annaka M., Ogata Y., and Nakahira T. Swelling behavior of covalently cross-linked gellan gels. Journal of Physical Chemistry B 104 (2000) 6755-6760
2. Barreiro-Iglesias R., Coronilla R., Concheiro A., and Alvarez-Lorenzo C. Preparation of chitosan beads by simultaneous cross-linking/insolubilisation in basic pH: Rheological optimisation and drug loading/release behaviour. European Journal of Pharmaceutical Sciences 24 (2005) 77-84
3. De Miguel I., Rieumajou V., and Betbeder D. New methods to determine the extent of reaction of epichlorohydrin with maltodextrins. Carbohydrate Research 319 (1999) 17-23
4. Denizli B.K., Can H.K., Rzaev Z.M.O., and Guner A. Preparation conditions and swelling equilibria of dextran hydrogels prepared by some cross-linking agents. Polymer 45 (2004) 6431-6435
5. Ellis A., and Jacquier J.-C. Manufacture of food grade κ-carrageenan microspheres. Journal of Food Engineering 94 3-4 (2009) 316-320
6. George M., and Abraham T.E. Polyionic hydrocolloids for the intestinal delivery of protein drugs: Alginate and chitosan - a review. Journal of Controlled Release 114 (2006) 1-14
7. Guner A., Akman O., and Rzaev Z.M.O. Cross-linking of dextran with some selective Cl-, P- and N-containing functional substances in aqueous solutions. Reactive and Functional Polymers 47 (2001) 55-65
8. Hirsch J.B., and Kokini J.L. Understanding the mechanism of cross-linking agents (POCl(3), STMP, and EPI) through swelling behavior and pasting properties of cross-linked waxy maize starches (1). Cereal Chemistry 79 (2002) 102-107
9. Hjerde T., Smidsrød O., and Christensen B.E. Analysis of the conformational properties of κ and i-carrageenan by size-exclusion chromatography combined with low-angle laser light scattering. Biopolymers 49 (1999) 71-80
10. ISO13320 Particle Size Analysis, (1999). Laser diffraction methods. Part 1: General principles.
11. Jacquier J.-C., MacArtain P., and Dawson K.A. Hydrophobically modified calcium-induced k-carrageenan. Progress in Colloids and Polymer Science 118 (2001) 127-131
12. Lee K.Y., Rowley J.A., Eiselt P., Moy E.M., Bouhadir K.H., and Mooney D.J. Controlling mechanical and swelling properties of alginate hydrogels independently by cross-linker type and cross-linking density. Macromolecules 33 (2000) 4291-4294
13. MacArtain P., Jacquier J.C., and Dawson K.A. Physical characteristics of calcium induced κ-carrageenan networks. Carbohydrate Polymers 53 4 (2003) 395-400
14. Moe S.T., Skjak-Brak G., Elgsaeter A., and Smidsrod O. Swelling of covalently cross-linked alginate gels: Influence of ionic solutes and nonpolar solvents. Macromolecules 26 (1993) 3589-3597
15. Morris E.R., Rees D.A., and Robinson G. Cation-specific aggregation of carrageenan helices: Domain model of polymer gel structure. Journal of Molecular Biology 138 2 (1980) 349-362
16. Sankalia M.G., Mashru R.C., Sankalia J.M., and Sutariya V.B. Stability improvement of alpha-amylase entrapped in kappa-carrageenan beads: Physicochemical characterization and optimization using composite index. International Journal of Pharmaceutics 312 (2006) 1-14
17. Sipahigil O., and Dortunc B. Preparation and in vitro evaluation of verapamil HCl and ibuprofen containing carrageenan beads. International Journal of Pharmaceutics 228 (2001) 119-128
18. Yeh A.-I., and Yeh S.-L. Some characteristics of hydroxypropylated cross-linked rice starch. Cereal Chemistry 70 (1993) 596-601
19. Zessen E.v., Tramper J., Rinzema A., and Beeftink H.H. Fluidized-bed and packed-bed characteristics of gel beads. Chemical Engineering Journal 115 (2005) 103-111