Preparation of chitosan beads by simultaneous cross-linking/ insolubilisation in basic pH: Rheological optimisation and drug loading/release behaviour

European Journal of Pharmaceutical Sciences

Volumn 24, Issue 1, 2005, Pages 77-84

  Barreiro Iglesias, R ^a   Coronilla, R ^a   Concheiro, A ^a   Alvarez Lorenzo, C ^a  

^a UNIVERSIDAD DE SANTIAGO DE CHILE   (Chile)

Author keywords

Chitosan cross linking; Chitosan deacetylation; Glutaraldehyde; Metronidazole; Microparticles; Oscillatory rheometry

Indexed keywords

ACETIC ACID; BUFFER; CHITOSAN; GLUTARALDEHYDE; HYDROCHLORIC ACID; METRONIDAZOLE; NANOPARTICLE; PHOSPHATE; SODIUM HYDROXIDE;

AQUEOUS SOLUTION; ARTICLE; CONCENTRATION RESPONSE; CROSS LINKING; DRUG FORMULARY; DRUG RELEASE; DRUG SOLUBILITY; DRUG SYNTHESIS; ENVIRONMENT; FLOW KINETICS; GEL; MOLECULAR WEIGHT; PH MEASUREMENT; PRIORITY JOURNAL; REACTION OPTIMIZATION; SENSITIVITY ANALYSIS; STOMACH; TECHNIQUE; TEMPERATURE DEPENDENCE;

CHITOSAN; CROSS-LINKING REAGENTS; DRUG CARRIERS; HYDROGEN-ION CONCENTRATION; RHEOLOGY; SOLUBILITY;

EID: 11144234232     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2004.09.013     Document Type: Article

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