Effect of lycopene and epigallocatechin-3-gallate against 3-nitropropionic acid induced cognitive dysfunction and glutathione depletion in rat: A novel nitric oxide mechanism

Food and Chemical Toxicology

Volumn 47, Issue 10, 2009, Pages 2522-2530

  Kumar, Puneet ^a   Kumar, Anil ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

3 Nitropropionic acid; Epigallocatechin gallate; Huntington's disease; Lycopene; Nitric oxide; Oxidative stress

Indexed keywords

3 NITROPROPIONIC ACID; ARGININE; EPIGALLOCATECHIN GALLATE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; LYCOPENE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN PROTECTION; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS STRIATUM; DRUG EFFICACY; HIPPOCAMPUS; MALE; MAZE TEST; MEMORY DISORDER; NONHUMAN; OXIDATIVE STRESS; RAT;

ANIMALS; BRAIN; CAROTENOIDS; CATECHIN; DISEASE MODELS, ANIMAL; GLUTATHIONE; HUNTINGTON DISEASE; MALE; MAZE LEARNING; MEMORY DISORDERS; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; OXIDATIVE STRESS; RATS;

ANIMALIA; RATTUS;

EID: 69549129286     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.07.011     Document Type: Article

References (46)

1. Aktas O., Prozorovski T., Smorodchenko A., Savaskan N.E., Lauster R., Kloetzel P.M., Infante-Duarte C., Brocke S., and Zipp F. Green tea epigallocatechin-3-gallate mediates T cellular NF-kappa B inhibition and exerts neuroprotection in autoimmune encephalomyelitis. J. Immunol. 173 (2004) 5794-5800
2. Akula K.K., Dhir A., and Kulkarni S.K. Nitric oxide signaling pathway in the anti-convulsant effect of adenosine against pentylenetetrazol-induced seizure threshold in mice. Eur. J. Pharmacol. 587 (2008) 129-134
3. Alston T.A., Mela L., and Bright H.J. 3-Nitropropionate, the toxic substance of Indigofera, is a suicide inactivator of succinate dehydrogenase. Proc. Natl. Acad. Sci. USA 74 (1977) 3767-3771
4. Atessahin A., Ceribasi A.O., and Yilmaz S. Lycopene, a carotenoid, attenuates cyclosporine-induced renal dysfunction and oxidative stress in rats. Basic Clin. Pharmacol. Toxicol. 100 (2007) 372-376
5. Atessahin A., Yilmaz S., Karahan I., Ceribasi A.O., and Karaoglu A. Effects of lycopene against cisplatin-induced nephrotoxicity and oxidative stress in rats. Toxicology 212 (2005) 116-123
6. Beal M.F. Coenzyme Q10 administration and its potential for treatment of neurodegenerative diseases. Biofactors 9 (1999) 261-266
7. Brouillet E., Conde F., Beal M.F., and Hantraye P. Replicating Huntington's disease phenotype in experimental animals. Prog. Neurobiol. 59 (1999) 427-468
8. Cohen L.A. A review of animal model studies of tomato carotenoids, lycopene, and cancer chemoprevention. Exp. Biol. Med. (Maywood) 227 (2002) 864-868
9. Coles C.J., Edmondson D.E., and Singer T.P. Inactivation of succinate dehydrogenase by 3-nitropropionate. J. Biol. Chem. 254 (1979) 5161-5167
10. Devika P.T., and Stanely Mainzen Prince P. (-)-Epigallocatechingallate protects the mitochondria against the deleterious effects of lipids, calcium and adenosine triphosphate in isoproterenol induced myocardial infarcted male Wistar rats. J. Appl. Toxicol. 28 (2008) 938-944
11. Duckworth E.A., Koutouzis T.K., Borlongan C.V., Gordon M.N., Willing A.E., Cahill D.W., and Sanberg P.R. Rats receiving systemic 3-nitropropionic acid demonstrate impairment of memory in Morris water maze. Psychobiology 27 (1999) 561-566
12. Ehrnhoefer D.E., Duennwald M., Markovic P., Wacker J.L., Engemann S., Roark M., Legleiter J., Marsh J.L., Thompson L.M., Lindquist S., Muchowski P.J., and Wanker E.E. Green tea (-)-epigallocatechin-gallate modulates early events in Huntington misfolding and reduces toxicity in Huntington's disease models. Hum. Mol. Genet. 15 (2006) 2743-2751
13. Ellman G.L. Tissue sulfhydryl groups. Arch. Biochem. Biophys. 82 (1959) 70-77
14. Etus V., Altug T., Belce A., and Ceylan S. Green tea polyphenol (-)-epigallocatechin gallate prevents oxidative damage on periventricular white matter of infantile rats with hydrocephalus. Tohoku J. Exp. Med. 200 (2003) 203-209
15. Frautschy S.A., Hu W., Kim P., Miller S.A., Chu T., Harris-White M.E., and Cole G.M. Phenolic anti-inflammatory antioxidant reversal of a beta-induced cognitive deficits and neuropathology. Neurobiol. Aging 22 (2001) 993-1005
16. Gornall A.G., Bardawill C.J., and David M.M. Determination of serum proteins by means of the biuret reaction. J. Biol. Chem. 177 (1949) 751-766
17. Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
18. Hoth K.F., Paulsen J.S., Moser D.J., Tranel D., Clark L.A., and Bechara A. Patients with Huntington's disease have impaired awareness of cognitive, emotional, and functional abilities. J. Clin. Exp. Neuropsychol. 29 (2007) 365-376
19. Kuhad A., Sethi R., and Chopra K. Lycopene attenuates diabetes-associated cognitive decline in rats. Life Sci. 83 (2008) 128-134
20. Kumar P., and Kumar A. Neuroprotective effect of cyclosporine and FK506 against 3-nitropropionic acid induced cognitive dysfunction and glutathione redox in rat: possible role of nitric oxide. Neurosci. Res. 63 (2009) 302-314
21. Kumar P., and Kumar A. Possible role of sertraline against 3-nitropropionic acid induced behavioral, oxidative stress and mitochondrial dysfunctions in rat brain. Prog. Neuropsychopharmacol. Biol. Psychiatry 33 (2009) 100-108
22. Kumar P., Padi S.S., Naidu P.S., and Kumar A. Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms. Fundam. Clin. Pharmacol. 21 (2007) 297-306
23. Lee J.H., Song D.K., Jung C.H., Shin D.H., Park J., Kwon T.K., Jang B.C., Mun K.C., Kim S.P., Suh S.I., and Bae J.H. (-)-Epigallocatechin gallate attenuates glutamate-induced cytotoxicity via intracellular Ca modulation in PC12 cells. Clin. Exp. Pharmacol. Physiol. 31 (2004) 530-536
24. Lin Y.L., and Lin J.K. (-)-Epigallocatechin-3-gallate blocks the induction of nitric oxide synthase by down-regulating lipopolysaccharide-induced activity of transcription factor nuclear factor-kappaB. Mol. Pharmacol. 52 (1997) 465-472
25. Ludolph A.C., He F., Spencer P.S., Hammerstad J., and Sabri M. 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. Can. J. Neurol. Sci. 18 (1991) 492-498
26. Mandel S.A., Avramovich-Tirosh Y., Reznichenko L., Zheng H., Weinreb O., Amit T., and Youdim M.B. Multifunctional activities of green tea catechins in neuroprotection. Modulation of cell survival genes, iron-dependent oxidative stress and PKC signaling pathway. Neurosignals 14 (2005) 46-60
27. Mandel S.A., and Youdim M.B.H. Catechin polyphenols: neurodegeneration and neuroprotection in neurodegenerative diseases. Free Radical Bio. Med. 37 (2004) 304-317
28. Montoya A., Price B.H., Menear M., and Lepage M. Brain imaging and cognitive dysfunctions in Huntington's disease. J. Psychiatry Neurosci. 31 (2006) 21-29
29. Rafi M.M., Yadav P.N., and Reyes M. Lycopene inhibits LPS-induced proinflammatory mediator inducible nitric oxide synthase in mouse macrophage cells. J. Food Sci. 72 (2007) S069-S074
30. Rencuzogullari N., and Erdogan S. Oral administration of lycopene reverses cadmium-suppressed body weight loss and lipid peroxidation in rats. Biol. Trace Elem. Res. 118 (2007) 175-183
31. Rezai-Zadeh K., Arendash G.W., Hou H., Fernandez F., Jensen M., Runfeldt M., Shytle R.D., and Tan J. Green tea epigallocatechin-3-gallate (EGCG) reduces beta-amyloid mediated cognitive impairment and modulates tau pathology in Alzheimer transgenic mice. Brain Res. 1214 (2008) 177-187
32. Rezai-Zadeh K., Shytle D., Sun N., Mori T., Hou H., Jeanniton D., Ehrhart J., Townsend K., Zeng J., Morgan D., Hardy J., Town T., and Tan J. Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice. J. Neurosci. 25 (2005) 8807-8814
33. Rosenstock T.R., Abilio V.C., Frussa-Filho R., Kiyomoto B.H., and Smaili S.S. Old mice present increased levels of succinate dehydrogenase activity and lower vulnerability to dyskinetic effects of 3-nitropropionic acid. Pharmacol. Biochem. Behav. 91 (2009) 327-332
34. Rosenstock T.R., Carvalho A.C., Jurkiewicz A., Frussa-Filho R., and Smaili S.S. Mitochondrial calcium, oxidative stress and apoptosis in a neurodegenerative disease model induced by 3-nitropropionic acid. J. Neurochem. 88 (2004) 1220-1228
35. Salvemini F., Franze A., Iervolino A., Filosa S., Salzano S., and Ursini M.V. Enhanced glutathione levels and oxidoresistance mediated by increased glucose-6-phosphate dehydrogenase expression. J. Biol. Chem. 274 (1999) 2750-2757
36. Schulz J.B., Lindenau J., Seyfried J., and Dichgans J. Glutathione, oxidative stress and neurodegeneration. Eur. J. Biochem. 267 (2000) 4904-4911
37. Sengupta A., Ghosh S., Das R.K., Bhattacharjee S., and Bhattacharya S. Chemopreventive potential of diallylsulfide, lycopene and theaflavin during chemically induced colon carcinogenesis in rat colon through modulation of cyclooxygenase-2 and inducible nitric oxide synthase pathways. Eur. J. Cancer Prev. 15 (2006) 301-305
38. Shear D.A., Haik K.L., and Dunbar G.L. Creatine reduces 3-nitropropionic-acid-induced cognitive and motor abnormalities in rats. Neuroreport 11 (2000) 1833-1837
39. Sugino T., Nozaki K., Takagi Y., Hattori I., Hashimoto N., and Yodoi J. Expression and distribution of redox regulatory protein, thioredoxin after metabolic impairment by 3-nitropropionic acid in rat brain. Neurosci. Lett. 275 (1999) 145-148
40. Teunissen C.E., Steinbusch H.W., Angevaren M., Appels M., de Bruijn C., Prickaerts J., and de Vente J. Behavioural correlates of striatal glial fibrillary acidic protein in the 3-nitropropionic acid rat model: disturbed walking pattern and spatial orientation. Neuroscience 105 (2001) 153-167
41. Tunez I., Feijoo M., Collado J.A., Medina F.J., Pena J., Munoz Mdel C., Jimena I., Franco F., Rueda I., Muntane J., and Montilla P. Effect of testosterone on oxidative stress and cell damage induced by 3-nitropropionic acid in striatum of ovariectomized rats. Life Sci. 80 (2007) 1221-1227
42. Turk G., Atessahin A., Sonmez M., Yuce A., and Ceribasi A.O. Lycopene protects against cyclosporine A-induced testicular toxicity in rats. Theriogenology 67 (2007) 778-785
43. Unno K., Takabayashi F., Kishido T., and Oku N. Suppressive effect of green tea catechins on morphologic and functional regression of the brain in aged mice with accelerated senescence (SAMP10). Exp. Gerontol. 39 (2004) 1027-1034
44. Vonsattel J.P., and DiFiglia M. Huntington disease. J. Neuropathol. Exp. Neurol. 57 (1998) 369-384
45. Zahler W.L., and Cleland W.W. A specific and sensitive assay for disulfides. J. Biol. Chem. 243 (1968) 716-719
46. Zhang B., Safa R., Rusciano D., and Osborne N.N. Epigallocatechin gallate, an active ingredient from green tea, attenuates damaging influences to the retina caused by ischemia/reperfusion. Brain Res. 1159 (2007) 40-53