Clinical and biochemical diagnosis of small-vessel disease in acute ischemic stroke

Journal of the Neurological Sciences

Volumn 285, Issue 1-2, 2009, Pages 185-190

  Brouns, Raf ^a,b,c   Van Den Bossche, Jan ^b   De Surgeloose, Didier ^b   Sheorajpanday, Rishi ^b   De Deyn, Peter P ^a,b  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b MIDDELHEIM HOSPITAL   (Belgium)

^c UNIVERSITY HOSPITAL BRUSSELS   (Belgium)

Author keywords

D dimer; Oxfordshire Community Stroke Project classification; Stroke; Stroke etiology; Triage Stroke Panel; VIDAS

Indexed keywords

ALTEPLASE; D DIMER; UROKINASE;

AGED; ARTICLE; ASSAY; BLOOD SAMPLING; CEREBROVASCULAR ACCIDENT; CHEMICAL ANALYSIS; CLINICAL ASSESSMENT; CLINICAL EVALUATION; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISEASE CLASSIFICATION; FEMALE; HUMAN; KAPPA STATISTICS; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

ACUTE DISEASE; AGED; BRAIN ISCHEMIA; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; HUMANS; INTRACRANIAL ARTERIAL DISEASES; MALE; ROC CURVE; SENSITIVITY AND SPECIFICITY; STROKE; TIME FACTORS;

EID: 69549118434     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.06.032     Document Type: Article

References (35)

1. Bamford J., Sandercock P., Jones L., and Warlow C. The natural history of lacunar infarction: the Oxfordshire Community Stroke Project. Stroke 18 (1987) 545-551
2. Wahlgren N., Ahmed N., Davalos A., et al. Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study. Lancet 369 (2007) 275-282
3. Christou I., Felberg R.A., Demchuk A.M., et al. Intravenous tissue plasminogen activator and flow improvement in acute ischemic stroke patients with internal carotid artery occlusion. J Neuroimaging 12 (2002) 119-123
4. Furlan A., Higashida R., Wechsler L., et al. Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism. JAMA 282 (1999) 2003-2011
5. Smith W.S., Sung G., Starkman S., et al. Safety and efficacy of mechanical embolectomy in acute ischemic stroke: results of the MERCI trial. Stroke 36 (2005) 1432-1438
6. Brouns R., Sheorajpanday R., Wauters A., De S.D., Marien P., and De Deyn P.P. Evaluation of lactate as a marker of metabolic stress and cause of secondary damage in acute ischemic stroke or TIA. Clin Chim Acta 397 (2008) 27-31
7. Uyttenboogaart M., Koch M.W., Stewart R.E., Vroomen P.C., Luijckx G.J., and De Keyser J. Moderate hyperglycaemia is associated with favourable outcome in acute lacunar stroke. Brain 130 (2007) 1626-1630
8. Waxman S. Molecular mechanisms of subcortical versus cortical infarction. In: Donnan G., Norrving B., Bamford J., and Bogousslavsky J. (Eds). Subcortical stroke (2002), Oxford Medical Publications, Oxford, U.K. 67-83
9. Aslanyan S., Weir C.J., Muir K.W., and Lees K.R. Magnesium for treatment of acute lacunar stroke syndromes: further analysis of the IMAGES trial. Stroke 38 (2007) 1269-1273
10. Aerden L., van Raak E., Boreas A., Kessels A., and Lodder J. Common drugs in acute ischemic stroke and their influence on outcome: an observational study in 1013 stroke patients. Clin Neuropharmacol 31 (2008) 74-79
11. Greenberg S.M. Small vessels, big problems. N Engl J Med 354 (2006) 1451-1453
12. Phillips S.J., Dai D., Mitnitski A., et al. Clinical diagnosis of lacunar stroke in the first 6 hours after symptom onset: analysis of data from the glycine antagonist in neuroprotection (GAIN) Americas trial. Stroke 38 (2007) 2706-2711
13. Smith C.J., Emsley H.C., Libetta C.M., et al. The Oxfordshire Community Stroke Project classification in the early hours of ischemic stroke and relation to infarct site and size on cranial computed tomography. J Stroke Cerebrovasc Dis 10 (2001) 205-209
14. Rajajee V., Kidwell C., Starkman S., et al. Diagnosis of lacunar infarcts within 6 hours of onset by clinical and CT criteria versus MRI. J Neuroimaging 18 (2008) 66-72
15. Lee L.J., Kidwell C.S., Alger J., Starkman S., and Saver J.L. Impact on stroke subtype diagnosis of early diffusion-weighted magnetic resonance imaging and magnetic resonance angiography. Stroke 31 (2000) 1081-1089
16. Feinberg W.M., Bruck D.C., Ring M.E., and Corrigan Jr. J.J. Hemostatic markers in acute stroke. Stroke 20 (1989) 592-597
17. Fisher M., and Francis R. Altered coagulation in cerebral ischemia. Platelet, thrombin, and plasmin activity. Arch Neurol 47 (1990) 1075-1079
18. Fon E.A., Mackey A., Cote R., et al. Hemostatic markers in acute transient ischemic attacks. Stroke 25 (1994) 282-286
19. Takano K., Yamaguchi T., and Uchida K. Markers of a hypercoagulable state following acute ischemic stroke. Stroke 23 (1992) 194-198
20. Ageno W., Finazzi S., Steidl L., et al. Plasma measurement of D-dimer levels for the early diagnosis of ischemic stroke subtypes. Arch Intern Med 162 (2002) 2589-2593
21. Brouns R., Heylen E., Sheorajpanday R., et al. Carboxypeptidase U (TAFIa) decreases the efficacy of thrombolytic therapy in ischemic stroke patients. Clin Neurol Neurosurg 111 (2009) 165-170
22. Brouns R., Sheorajpanday R., Kunnen J., De Surgeloose D., and De Deyn P.P. Clinical, biochemical and neuroimaging parameters after thrombolytic therapy predict long-term stroke outcome. Eur Neurol 30 (2009) 9-15
23. Brouns R, Marescau B, Possemiers I, Sheorajpanday R, De Deyn PP. Dimethylarginine levels in cerebrospinal fluid of hyperacute ischemic stroke patients are associated with stroke severity. Neurochem Res 2009, Mar 19 [Electronic publication ahead of print]. doi:10.1007/s11064-009-9954-3.
24. Brott T., Adams Jr. H.P., Olinger C.P., et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke 20 (1989) 864-870
25. Bamford J. Clinical examination in diagnosis and subclassification of stroke. Lancet 339 (1992) 400-402
26. Hacke W., Kaste M., Bogousslavsky J., et al. European Stroke Initiative recommendations for stroke management-update 2003. Cerebrovasc Dis 16 (2003) 311-337
27. Adams Jr. H.P., Bendixen B.H., Kappelle L.J., et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke 24 (1993) 35-41
28. Pittet J.L., de M.P., Reber G., et al. VIDAS D-dimer: fast quantitative ELISA for measuring D-dimer in plasma. Clin Chem 42 (1996) 410-415
29. Triage Stroke Panel Product Insert. Version 22662en Rev.C. 2006;13-23.
30. Dempfle C.E., Zips S., Ergul H., and Heene D.L. The Fibrin Assay Comparison Trial (FACT): evaluation of 23 quantitative D-dimer assays as basis for the development of D-dimer calibrators. FACT study group. Thromb Haemost 85 (2001) 671-678
31. Gardiner C., Pennaneac'h C., Walford C., Machin S.J., and Mackie I.J. An evaluation of rapid D-dimer assays for the exclusion of deep vein thrombosis. Br J Haematol 128 (2005) 842-848
32. Heim S.W., Schectman J.M., Siadaty M.S., and Philbrick J.T. D-dimer testing for deep venous thrombosis: a metaanalysis. Clin Chem 50 (2004) 1136-1147
33. Ghys T., Achtergael W., Verschraegen I., Leus B., and Jochmans K. Diagnostic accuracy of the Triage((R)) D-dimer test for exclusion of venous thromboembolism in outpatients. Thromb Res 121 (2008) 735-741
34. Wardlaw J.M., Sandercock P.A., Dennis M.S., and Starr J. Is breakdown of the blood-brain barrier responsible for lacunar stroke, leukoaraiosis, and dementia?. Stroke 34 (2003) 806-812
35. Ay H., Benner T., Arsava E.M., et al. A computerized algorithm for etiologic classification of ischemic stroke: the causative classification of stroke system. Stroke 38 (2007) 2979-2984