Adenosine A2A receptor deficiency exacerbates white matter lesions and cognitive deficits induced by chronic cerebral hypoperfusion in mice

Journal of the Neurological Sciences

Volumn 285, Issue 1-2, 2009, Pages 39-45

  Duan, Wei ^a   Gui, Li ^a   Zhou, Zhujuan ^a   Liu, Yong ^a   Tian, Hong ^a   Chen, Jiang Fan ^b   Zheng, Jian ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine A2A receptor; Chronic cerebral hypoperfusion; Inflammatory cytokine; Knock out; White matter lesions

Indexed keywords

ADENOSINE A2A RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; CYTOKINE;

ADENOSINE A2A RECEPTOR DEFICIENCY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN CORTEX; BRAIN DAMAGE; BRAIN PERFUSION; CHRONIC DISEASE; COGNITIVE DEFECT; CONTROLLED STUDY; CORPUS CALLOSUM; DEMYELINATING DISEASE; DISEASE EXACERBATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; WHITE MATTER; WORKING MEMORY; ANIMAL; ASTROCYTE; BRAIN; BRAIN CIRCULATION; C57BL MOUSE; CAROTID ARTERY OBSTRUCTION; COMMON CAROTID ARTERY; DISEASE MODEL; GENETICS; MALE; MAZE TEST; METABOLISM; MICROGLIA; MOUSE MUTANT; MYELINATED NERVE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SHORT TERM MEMORY; VASCULARIZATION;

ANIMALS; ASTROCYTES; BRAIN; CAROTID ARTERY, COMMON; CAROTID STENOSIS; CEREBROVASCULAR CIRCULATION; COGNITION DISORDERS; CYTOKINES; DEMYELINATING DISEASES; DISEASE MODELS, ANIMAL; MALE; MAZE LEARNING; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NERVE FIBERS, MYELINATED; RECEPTOR, ADENOSINE A2A; RNA, MESSENGER;

EID: 69549116250     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.05.010     Document Type: Article

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