Controversial discussion: Bleeding tendency with Ginkgo biloba extract?;Kontroverse diskussion: Blutungsneigung durch Ginkgo-biloba-extrakt?

Pharmazie in Unserer Zeit

Volumn 38, Issue 5, 2009, Pages 440-446

  Kloft, Charlotte ^a   Kellermann, Andrea ^b  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 7; GINKGO BILOBA EXTRACT; PROTHROMBIN; THROMBOPLASTIN; PLANT EXTRACT;

BLEEDING TENDENCY; CLINICAL TRIAL; DRUG MECHANISM; HUMAN; NOTE; PARTIAL THROMBOPLASTIN TIME; PHARMACOEPIDEMIOLOGY; BLEEDING; BLOOD CLOTTING; BLOOD VISCOSITY; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; EVIDENCE BASED MEDICINE; GINKGO BILOBA; REVIEW; THROMBOCYTE AGGREGATION;

BLOOD COAGULATION; BLOOD VISCOSITY; EVIDENCE-BASED MEDICINE; GINKGO BILOBA; HEMORRHAGE; HUMANS; PLANT EXTRACTS; PLATELET AGGREGATION;

EID: 69549102907     PISSN: 00483664     EISSN: 16151003     Source Type: Journal    
DOI: 10.1002/pauz.200900332     Document Type: Note

References (12)

1. Schwabe, U., Paffrath, D.: Arzneiverordnungsreport 2008, Springer Heidelberg (2008).
2. Monographie der Kommission E: Ginkgo-biloba-Blätter, Trockenextrakt (35-67:1) extrahiert mit Aceton-Wass. BAnz. Nr. 133, 19.07.1994.
3. Institut für Qualität und Wirtschaftlichkeit im Gesundheitswesen: Ginkgohaltige Präparate bei Alzheimer Demenz. Abschlussbericht A05-19B. Köln: IQWIG (2008).
4. Bone, K.: Potential interaction of Ginkgo biloba leaf with antiplatelet or anticoagulant drugs. Mol. Nutr. Food Res. 52 (2008), 764-771.
5. Sackett, D., Rosenberg, W., Gray, M., Haynes, R., Richardson, S.: Evidence based medicine: what it is and what it isn't. Brit. Med. J. 312 (1996), 71-72.
6. Thews, G., Mutschler, E., Vaupel, P.: Anatomie, Physiologie, Pathophysiologie des Menschen, WVG Stuttgart (2007).
7. Aktories, K., Förstermann, U., Hofmann, F., Starke, K.: Allgemeine und spezielle Pharmakologie und Toxikologie, Elsevier München (2009).
8. Diamond, B., Shifflett, S., Feiwel, N., Matheis, R., Noskin, O., Richards, J., Schoenberger, N.: Ginkgo biloba Extract: Mechanisms and Clinial Indications. Arch. Phys. Med. Rehabil. 81 (2000), 668-678.
9. Koch, E.: Inhibition of platelet activating factor (PAF)-induced aggregation of human thrombocytes by ginkgolides: considerations on possible bleeding complications after oral intake of Ginkgo biloba extracts. Phytomed. 12 (2005), 10-16.
10. Zylka-Menhorn, V., Findeisen, P.: Laborwerte im Bertungsgespräch, Govi-Verlag Eschborn (2004).
11. Oxford Centre for Evidence-based Medicine. Levels of Evidence, März 2009 (http://www.cebm.net/index.aspx?o=1025#levels, Zugriff: 04.05.2009).
12. DeKosky, S.T., et al.: Ginkgo biloba for prevention of dementia: a randomized controlled trial.. J. Am. Med. Assoc. 300 (2008), 2253-2262.