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Volumn 35, Issue 2, 2009, Pages 329-336

hTERT promotes the invasion of telomerase-negative tumor cells in vitro

Author keywords

Alternative lengthening of telomeres; Human telomerase reverse transcriptase; Invasion; Metastasis; Relative telomere length; U2OS

Indexed keywords

TELOMERASE REVERSE TRANSCRIPTASE; TELOMERASE; TERT PROTEIN, HUMAN;

EID: 69449099710     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo_00000344     Document Type: Article
Times cited : (41)

References (29)
  • 1
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB and Greider CW: Telomeres shorten during ageing of human fibroblasts. Nature 345: 458-460, 1990.
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 2
    • 2442455288 scopus 로고    scopus 로고
    • Telomeres are double-strand DNA breaks hidden from DNA damage responses
    • Shay JW and Wright WE: Telomeres are double-strand DNA breaks hidden from DNA damage responses. Mol Cell 14: 420-421, 2004.
    • (2004) Mol Cell , vol.14 , pp. 420-421
    • Shay, J.W.1    Wright, W.E.2
  • 3
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase activity in Tetrahymena extracts
    • Greider CW and Blackburn EH: Identification of a specific telomere terminal transferase activity in Tetrahymena extracts. Cell 43: 405-413, 1985.
    • (1985) Cell , vol.43 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 4
    • 33745862398 scopus 로고    scopus 로고
    • The biogenesis and regulation of telomerase holoenzymes
    • Collins K: The biogenesis and regulation of telomerase holoenzymes. Nat Rev Mol Cell Biol 7: 484-494, 2006.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 484-494
    • Collins, K.1
  • 6
  • 7
    • 0002730513 scopus 로고    scopus 로고
    • Determination of telomerase activity and its subunits in different gastric lesions
    • Yang SM, Fang DC, Luo YH, Lu R, Yang JL and Liu WW: Determination of telomerase activity and its subunits in different gastric lesions. Chin J Cancer 20: 23-27, 2001.
    • (2001) Chin J Cancer , vol.20 , pp. 23-27
    • Yang, S.M.1    Fang, D.C.2    Luo, Y.H.3    Lu, R.4    Yang, J.L.5    Liu, W.W.6
  • 8
    • 0034832792 scopus 로고    scopus 로고
    • Alterations of telomerase activity and terminal restriction fragment in gastric cancer and its premalignant lesions
    • Yang SM, Fang DC, Luo YH, Lu R, Battle PD and Liu WW: Alterations of telomerase activity and terminal restriction fragment in gastric cancer and its premalignant lesions. J Gastroenterol Hepatol 16: 876-882, 2001.
    • (2001) J Gastroenterol Hepatol , vol.16 , pp. 876-882
    • Yang, S.M.1    Fang, D.C.2    Luo, Y.H.3    Lu, R.4    Battle, P.D.5    Liu, W.W.6
  • 10
    • 0030697342 scopus 로고    scopus 로고
    • Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
    • Bryan TM, Englezou A, Dalla-Pozza L, Dunham MA and Reddel RR: Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 3: 1271-1274, 1997.
    • (1997) Nat Med , vol.3 , pp. 1271-1274
    • Bryan, T.M.1    Englezou, A.2    Dalla-Pozza, L.3    Dunham, M.A.4    Reddel, R.R.5
  • 11
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan TM, Englezou A, Gupta J, Bacchetti S and Reddel RR: Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J 14: 4240-4248, 1995.
    • (1995) EMBO J , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 12
    • 27744527486 scopus 로고    scopus 로고
    • The first molecular details of ALT in human tumor cells
    • Muntoni A and Reddel RR: The first molecular details of ALT in human tumor cells. Hum Mol Genet 14: R191-R196, 2005.
    • (2005) Hum Mol Genet , vol.14
    • Muntoni, A.1    Reddel, R.R.2
  • 15
    • 0037224923 scopus 로고    scopus 로고
    • Telomere-based crisis: Functional differences between telomerase activation and ALT in tumor progression
    • Chang S, Khoo CM, Naylor ML, Maser RS and DePinho RA: Telomere-based crisis: functional differences between telomerase activation and ALT in tumor progression. Gene Dev 17: 88-100, 2003.
    • (2003) Gene Dev , vol.17 , pp. 88-100
    • Chang, S.1    Khoo, C.M.2    Naylor, M.L.3    Maser, R.S.4    DePinho, R.A.5
  • 16
    • 2942538551 scopus 로고    scopus 로고
    • Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice
    • Canela A, Martin-Caballero J, Flores JM and Blasco MA: Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice. Mol Cell Biol 24: 4275-4293, 2004.
    • (2004) Mol Cell Biol , vol.24 , pp. 4275-4293
    • Canela, A.1    Martin-Caballero, J.2    Flores, J.M.3    Blasco, M.A.4
  • 18
    • 4344567360 scopus 로고    scopus 로고
    • Progressive loss of malignant behavior in telomerase-negative tumorigenic adrenocortical cells and restoration of tumorigenicity by human telomerase reverse transcriptase
    • Sun BC, Huang Q, Liu SX, Chen MZ, Hawks CL, Wang LS, Zhang CH and Hornsby PJ: Progressive loss of malignant behavior in telomerase-negative tumorigenic adrenocortical cells and restoration of tumorigenicity by human telomerase reverse transcriptase. Cancer Res 64: 6144-6151, 2004.
    • (2004) Cancer Res , vol.64 , pp. 6144-6151
    • Sun, B.C.1    Huang, Q.2    Liu, S.X.3    Chen, M.Z.4    Hawks, C.L.5    Wang, L.S.6    Zhang, C.H.7    Hornsby, P.J.8
  • 19
    • 64549092429 scopus 로고    scopus 로고
    • Induction of anti-tumor immunity by dendritic cells transduced with hTERT recombinant adenovirus in mice
    • Chen L, Tang XD, Yu ST, Ai ZH, Fang DC, Cai YG, Luo YH, Liang GP and Yang SM: Induction of anti-tumor immunity by dendritic cells transduced with hTERT recombinant adenovirus in mice. J Pathol 217: 685-692, 2009.
    • (2009) J Pathol , vol.217 , pp. 685-692
    • Chen, L.1    Tang, X.D.2    Yu, S.T.3    Ai, Z.H.4    Fang, D.C.5    Cai, Y.G.6    Luo, Y.H.7    Liang, G.P.8    Yang, S.M.9
  • 20
    • 2342419515 scopus 로고    scopus 로고
    • Telomere measurement by quantitative PCR
    • Cawthon RM: Telomere measurement by quantitative PCR. Nucleic Acids Res 30: e47, 2002.
    • (2002) Nucleic Acids Res , vol.30
    • Cawthon, R.M.1
  • 21
    • 42249104693 scopus 로고    scopus 로고
    • Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro
    • Yang SM, Fang DC, Yang JL, Chen L, Luo YH and Liang GP: Antisense human telomerase reverse transcriptase could partially reverse malignant phenotypes of gastric carcinoma cell line in vitro. Eur J Cancer Prev 17: 209-217, 2008.
    • (2008) Eur J Cancer Prev , vol.17 , pp. 209-217
    • Yang, S.M.1    Fang, D.C.2    Yang, J.L.3    Chen, L.4    Luo, Y.H.5    Liang, G.P.6
  • 23
    • 0036232628 scopus 로고    scopus 로고
    • Mechanical properties of hepatocellular carcinoma cells
    • Zhang G, Long M, Wu ZZ and Yu WQ: Mechanical properties of hepatocellular carcinoma cells. World J Gastroenterol 8: 243-246, 2002.
    • (2002) World J Gastroenterol , vol.8 , pp. 243-246
    • Zhang, G.1    Long, M.2    Wu, Z.Z.3    Yu, W.Q.4
  • 24
    • 0033758365 scopus 로고    scopus 로고
    • Comparison of the viscoelastic properties of normal hepatocytes and hepatocellular carcinoma cells under cytoskeletal perturbation
    • Wu ZZ, Zhang G, Long M, Wang HB, Song GB and Cai SX: Comparison of the viscoelastic properties of normal hepatocytes and hepatocellular carcinoma cells under cytoskeletal perturbation. Biorheology 37: 279-290, 2000.
    • (2000) Biorheology , vol.37 , pp. 279-290
    • Wu, Z.Z.1    Zhang, G.2    Long, M.3    Wang, H.B.4    Song, G.B.5    Cai, S.X.6
  • 25
    • 0038056347 scopus 로고    scopus 로고
    • Telomerase modulates expression of growth-controlling genes and enhances cell proliferation
    • Smith LL, Coller HA and Roberts JM: Telomerase modulates expression of growth-controlling genes and enhances cell proliferation. Nat Cell Biol 5: 474-479, 2003.
    • (2003) Nat Cell Biol , vol.5 , pp. 474-479
    • Smith, L.L.1    Coller, H.A.2    Roberts, J.M.3
  • 26
    • 33746257301 scopus 로고    scopus 로고
    • Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-beta signaling
    • Geserick C, Tejera A, Gonzalez-Suarez E, Klatt P and Blasco MA: Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-beta signaling. Oncogene 25: 4310-4319, 2006.
    • (2006) Oncogene , vol.25 , pp. 4310-4319
    • Geserick, C.1    Tejera, A.2    Gonzalez-Suarez, E.3    Klatt, P.4    Blasco, M.A.5
  • 27
    • 48949085109 scopus 로고    scopus 로고
    • The many faces of telomerase: Emerging extratelomeric effects
    • Bollmann FM: The many faces of telomerase: emerging extratelomeric effects. Bioessays 30: 728-732, 2008.
    • (2008) Bioessays , vol.30 , pp. 728-732
    • Bollmann, F.M.1
  • 29
    • 37449023872 scopus 로고    scopus 로고
    • KAI1 gene suppresses invasion and metastasis of hepatocellular carcinoma MHCC97-H cells in vitro and in animal models
    • Yang JM, Peng ZH, Si SH, Liu WW, Luo YH and Ye ZY: KAI1 gene suppresses invasion and metastasis of hepatocellular carcinoma MHCC97-H cells in vitro and in animal models. Liver Int 1: 132-139, 2008.
    • (2008) Liver Int , vol.1 , pp. 132-139
    • Yang, J.M.1    Peng, Z.H.2    Si, S.H.3    Liu, W.W.4    Luo, Y.H.5    Ye, Z.Y.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.