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Volumn 23, Issue 9, 2009, Pages 1371-1384

The 26-amino acid β-motif of the Pit-1β transcription factor is a dominant and independent repressor domain

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; DNA; HISTONE DEACETYLASE; RAS PROTEIN; TRANSCRIPTION FACTOR PIT 1; TRANSCRIPTION FACTOR PIT 1 BETA; UNCLASSIFIED DRUG;

EID: 69449094080     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2008-0137     Document Type: Article
Times cited : (20)

References (55)
  • 1
    • 0024514212 scopus 로고
    • Purification of growth hormone-specific transcription factor GHF-1 containing homeobox
    • Castrillo JL, Bodner M, Karin M 1989 Purification of growth hormone-specific transcription factor GHF-1 containing homeobox. Science 243:814-817 (Pubitemid 19062640)
    • (1989) Science , vol.243 , Issue.4892 , pp. 814-817
    • Castrillo, J.-L.1    Bodner, M.2    Karin, M.3
  • 3
    • 0025014024 scopus 로고
    • Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1
    • DOI 10.1038/347528a0
    • Li S, Crenshaw 3rd EB, Rawson EJ, Simmons DM, Swanson LW, Rosenfeld MG 1990 Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1. Nature 347:528-533 (Pubitemid 20341541)
    • (1990) Nature , vol.347 , Issue.6293 , pp. 528-533
    • Li, S.1    Crenshaw III, E.B.2    Rawson, E.J.3    Simmons, D.M.4    Swanson, L.W.5    Rosenfeld, M.G.6
  • 4
    • 0028944265 scopus 로고
    • A novel pituitary transcription factor is produced by alternative splicing of the human GHF-1/PIT-1 gene
    • Delhase M, Vila V, Hooghe-Peters EL, Castrillo JL 1995 A novel pituitary transcription factor is produced by alternative splicing of the human GHF-1/PIT-1 gene. Gene 155:273-275
    • (1995) Gene , vol.155 , pp. 273-275
    • Delhase, M.1    Vila, V.2    Hooghe-Peters, E.L.3    Castrillo, J.L.4
  • 6
    • 0026596402 scopus 로고
    • Differential splicing of the GHF1 primary transcript gives rise to two functionally distinct homeodomain proteins
    • Theill LE, Hattori K, Lazzaro D, Castrillo JL, Karin M 1992 Differential splicing of the GHF1 primary transcript gives rise to two functionally distinct homeodomain proteins. EMBO J 11:2261-2269
    • (1992) EMBO J , vol.11 , pp. 2261-2269
    • Theill, L.E.1    Hattori, K.2    Lazzaro, D.3    Castrillo, J.L.4    Karin, M.5
  • 7
    • 0026578097 scopus 로고
    • Functional isoforms of Pit-1 generated by alternative messenger RNA splicing
    • Konzak KE, Moore DD 1992 Functional isoforms of Pit-1 generated by alternative messenger RNA splicing. Mol Endocrinol 6:241-247
    • (1992) Mol Endocrinol , vol.6 , pp. 241-247
    • Konzak, K.E.1    Moore, D.D.2
  • 8
    • 0031019977 scopus 로고    scopus 로고
    • Pit-1/growth hormone factor 1 splice variant expression in the rhesus monkey pituitary gland and the rhesus and human placenta
    • DOI 10.1210/jc.82.3.800
    • Schanke JT, Conwell CM, Durning M, Fisher JM, Golos TG 1997 Pit-1/growth hormone factor 1 splice variant expression in the rhesus monkey pituitary gland and the rhesus and human placenta. J Clin Endocrinol Metab 82:800-807 (Pubitemid 27106591)
    • (1997) Journal of Clinical Endocrinology and Metabolism , vol.82 , Issue.3 , pp. 800-807
    • Schanke, J.T.1    Conwell, C.M.2    Durning, M.3    Fisher, J.M.4    Golos, T.G.5
  • 9
    • 0026681032 scopus 로고
    • Structures of cDNAs encoding chum salmon pituitary-specific transcription factor, Pit-1/GHF-1
    • Ono M, Takayama Y 1992 Structures of cDNAs encoding chum salmon pituitary-specific transcription factor, Pit-1/GHF-1. Gene 116:275-279
    • (1992) Gene , vol.116 , pp. 275-279
    • Ono, M.1    Takayama, Y.2
  • 10
    • 0033636623 scopus 로고    scopus 로고
    • Complementary DNA cloning and ontogenic expression of pituitary-specific transcription factor of chickens (Gallus domesticus) from the pituitary gland
    • Van As P, Buys N, Onagbesan OM, Decuypere E 2000 Complementary DNA cloning and ontogenic expression of pituitary-specific transcription factor of chickens (Gallus domesticus) from the pituitary gland. Gen Comp Endocrinol 120:127-136
    • (2000) Gen Comp Endocrinol , vol.120 , pp. 127-136
    • Van As, P.1    Buys, N.2    Onagbesan, O.M.3    Decuypere, E.4
  • 11
    • 0031882405 scopus 로고    scopus 로고
    • Synthesis of turkey Pit-1 mRNA variants by alternative splicing and transcription initiation
    • Kurima K, Weatherly KL, Sharova L, Wong EA 1998 Synthesis of turkey Pit-1 mRNA variants by alternative splicing and transcription initiation. DNA Cell Biol 17:93-103 (Pubitemid 28084087)
    • (1998) DNA and Cell Biology , vol.17 , Issue.1 , pp. 93-103
    • Kurima, K.1
  • 13
    • 0026767630 scopus 로고
    • A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency
    • Radovick S, Nations M, Du Y, Berg LA, Weintraub BD, Wondisford FE 1992 A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency. Science 257:1115-1118
    • (1992) Science , vol.257 , pp. 1115-1118
    • Radovick, S.1    Nations, M.2    Du, Y.3    Berg, L.A.4    Weintraub, B.D.5    Wondisford, F.E.6
  • 14
    • 0141994779 scopus 로고    scopus 로고
    • Ras signaling and transcriptional synergy at a flexible Ets-1/Pit-1 composite DNA element is defined by the assembly of selective activation domains
    • DOI 10.1074/jbc.M302433200
    • Duval DL, Jean A, Gutierrez-Hartmann A 2003 Ras signaling and transcriptional synergy at a flexible Ets-1/Pit-1 composite DNA element is defined by the assembly of selective activation domains. J Biol Chem 278:39684-39696 (Pubitemid 37248530)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.41 , pp. 39684-39696
    • Duval, D.L.1    Jean, A.2    Gutierrez-Hartmann, A.3
  • 15
    • 33845988022 scopus 로고    scopus 로고
    • Differential utilization of transcription activation subdomains by distinct coactivators regulates Pit-1 basal and Ras responsiveness
    • DOI 10.1210/me.2006-0245
    • Duval DL, Jonsen MD, Diamond SE, Murapa P, Jean A, Gutierrez-Hartmann A 2007 Differential utilization of transcription activation subdomains by distinct coactivators regulates Pit-1 basal and Ras responsiveness. Mol Endocrinol 21:172-185 (Pubitemid 46041698)
    • (2007) Molecular Endocrinology , vol.21 , Issue.1 , pp. 172-185
    • Duval, D.L.1    Jonsen, M.D.2    Diamond, S.E.3    Murapa, P.4    Jean, A.5    Gutierrez-Hartmann, A.6
  • 17
    • 0035265684 scopus 로고    scopus 로고
    • CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box
    • DOI 10.1016/S1097-2765(01)00202-7
    • Zanger K, Radovick S, Wondisford FE 2001 CREB binding protein recruitment to the transcription complex requires growth factor-dependent phosphorylation of its GF box. Mol Cell 7:551-558 (Pubitemid 32706347)
    • (2001) Molecular Cell , vol.7 , Issue.3 , pp. 551-558
    • Zanger, K.1    Radovick, S.2    Wondisford, F.E.3
  • 18
    • 0032559420 scopus 로고    scopus 로고
    • The transcription factor GHF-1, but not the splice variant GHF-2, cooperates with thyroid hormone and retinoic acid receptors to stimulate rat growth hormone gene expression
    • DOI 10.1016/S0014-5793(97)01609-8, PII S0014579397016098
    • Sánchez-Pacheco A, Peña P, Palomino T, Güell A, Castrillo JL, Aranda A 1998 The transcription factor GHF-1, but not the splice variant GHF-2, cooperates with thyroid hormone and retinoic acid receptors to stimulate rat growth hormone gene expression. FEBS Lett 422:103-107 (Pubitemid 28052875)
    • (1998) FEBS Letters , vol.422 , Issue.1 , pp. 103-107
    • Sanchez-Pacheco, A.1    Pena, P.2    Palomino, T.3    Guell, A.4    Castrillo, J.L.5    Aranda, A.6
  • 19
    • 0024205756 scopus 로고
    • The POU domain is a bipartite DNa-binding structure
    • DOI 10.1038/336601a0
    • Sturm RA, Herr W 1988 The POU domain is a bipartite DNA-binding structure. Nature 336:601-604 (Pubitemid 19007319)
    • (1988) Nature , vol.336 , Issue.6199 , pp. 601-604
    • Sturm, R.A.1    Herr, W.2
  • 21
    • 0024792540 scopus 로고
    • Dissection of functional domains of the pituitary-specific transcription factor GHF-1
    • DOI 10.1038/342945a0
    • Theill LE, Castrillo JL, Wu D, Karin M 1989 Dissection of functional domains of the pituitary-specific transcription factor GHF-1. Nature 342:945-948 (Pubitemid 20021346)
    • (1989) Nature , vol.342 , Issue.6252 , pp. 945-948
    • Theill, L.E.1    Castrillo, J.-L.2    Wu, D.3    Karin, M.4
  • 22
    • 0029124988 scopus 로고
    • The POU domain: Versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain
    • Herr W, Cleary MA 1995 The POU domain: versatility in transcriptional regulation by a flexible two-in-one DNA-binding domain. Genes Dev 9:1679-1693
    • (1995) Genes Dev , vol.9 , pp. 1679-1693
    • Herr, W.1    Cleary, M.A.2
  • 23
    • 0030918673 scopus 로고    scopus 로고
    • POU domain family values: Flexibility, partnerships, and developmental codes
    • Ryan AK, Rosenfeld MG 1997 POU domain family values: flexibility, partnerships, and developmental codes. Genes Dev 11:1207-1225
    • (1997) Genes Dev , vol.11 , pp. 1207-1225
    • Ryan, A.K.1    Rosenfeld, M.G.2
  • 24
    • 0031057121 scopus 로고    scopus 로고
    • Structure of Pit-1 POU domain bound to DNA as a dimer: Unexpected arrangement and flexibility
    • Jacobson EM, Li P, Leon-del-Rio A, Rosenfeld MG, Aggarwal AK 1997 Structure of Pit-1 POU domain bound to DNA as a dimer: unexpected arrangement and flexibility. Genes Dev 11:198-212 (Pubitemid 27081896)
    • (1997) Genes and Development , vol.11 , Issue.2 , pp. 198-212
    • Jacobson, E.M.1    Li, P.2    Leon-Del-Rio, A.3    Rosenfeld, M.G.4    Aggarwal, A.K.5
  • 25
    • 0029113026 scopus 로고
    • Pit-1 binding to specific DNA sites as a monomer of dimer determines gene-specific use of a tyrosine-dependent synergy domain
    • Holloway JM, Szeto DP, Scully KM, Glass CK, Rosenfeld MG 1995 Pit-1 binding to specific DNA sites as a monomer of dimer determines gene-specific use of a tyrosine-dependent synergy domain. Genes Dev 9:1992-2006
    • (1995) Genes Dev , vol.9 , pp. 1992-2006
    • Holloway, J.M.1    Szeto, D.P.2    Scully, K.M.3    Glass, C.K.4    Rosenfeld, M.G.5
  • 26
    • 0028580550 scopus 로고
    • Multiple Pit-1 binding sites facilitate estrogen responsiveness of the prolactin gene
    • Nowakowski BE, Maurer RA 1994 Multiple Pit-1 binding sites facilitate estrogen responsiveness of the prolactin gene. Mol Endocrinol 8:1742-1749
    • (1994) Mol Endocrinol , vol.8 , pp. 1742-1749
    • Nowakowski, B.E.1    Maurer, R.A.2
  • 28
  • 30
    • 11244355063 scopus 로고    scopus 로고
    • The pituitary-specific transcription factor, Pit-1, can direct changes in the chromatin structure of the prolactin promoter
    • DOI 10.1210/me.2004-0016
    • Kievit P, Maurer RA 2005 The pituitary-specific transcription factor, Pit-1, can direct changes in the chromatin structure of the prolactin promoter. Mol Endocrinol 19:138-147 (Pubitemid 40065965)
    • (2005) Molecular Endocrinology , vol.19 , Issue.1 , pp. 138-147
    • Kievit, P.1    Maurer, R.A.2
  • 31
    • 0031037986 scopus 로고    scopus 로고
    • Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression
    • Bradford AP, Wasylyk C, Wasylyk B, Gutierrez-Hartmann A 1997 Interaction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression. Mol Cell Biol 17:1065-1074 (Pubitemid 27097335)
    • (1997) Molecular and Cellular Biology , vol.17 , Issue.3 , pp. 1065-1074
    • Bradford, A.P.1    Wasylyk, C.2    Wasylyk, B.3    Gutierrez-Hartmann, A.4
  • 33
    • 0031657937 scopus 로고    scopus 로고
    • A direct protein-protein interaction is involved in the cooperation between thyroid hormone and retinoic acid receptors and the transcription factor GHF-1
    • Palomino T, Sánchez-Pacheco A, Peña P, Aranda A 1998 A direct protein-protein interaction is involved in the cooperation between thyroid hormone and retinoic acid receptors and the transcription factor GHF-1. FASEB J 12:1201-1209 (Pubitemid 28418950)
    • (1998) FASEB Journal , vol.12 , Issue.12 , pp. 1201-1209
    • Palomino, T.1    Sanchez-Pacheco, A.2    Pena, P.3    Aranda, A.4
  • 34
    • 0033047790 scopus 로고    scopus 로고
    • Interaction between estrogen receptor and Pit-1 protein is influenced by estrogen in pituitary cells
    • DOI 10.1016/S0960-0760(99)00020-5, PII S0960076099000205
    • Ying C, Lin DH, Sarkar DK, Chen TT 1999 Interaction between estrogen receptor and Pit-1 protein is influenced by estrogen in pituitary cells. J Steroid Biochem Mol Biol 68:145-152 (Pubitemid 29242844)
    • (1999) Journal of Steroid Biochemistry and Molecular Biology , vol.68 , Issue.3-4 , pp. 145-152
    • Ying, C.1    Lin, D.-H.2    Sarkar, D.K.3    Chen, T.-T.4
  • 35
    • 0033323798 scopus 로고    scopus 로고
    • Synergistic activation of the prolactin promoter by vitamin D receptor and GHF-1: Role of the coactivators, CREB-binding protein and steroid hormone receptor coactivator-1 (SRC-1)
    • Castillo AI, Jimenez-Lara AM, Tolon RM, Aranda A 1999 Synergistic activation of the prolactin promoter by vitamin D receptor and GHF-1: role of the coactivators, CREB-binding protein and steroid hormone receptor coactivator-1 (SRC-1). Mol Endocrinol 13:1141-1154
    • (1999) Mol Endocrinol , vol.13 , pp. 1141-1154
    • Castillo, A.I.1    Jimenez-Lara, A.M.2    Tolon, R.M.3    Aranda, A.4
  • 36
    • 0037317399 scopus 로고    scopus 로고
    • A PIT-1 homeodomain mutant blocks the intranuclear recruitment of the CCAAT/enhancer binding protein α required for prolactin gene transcription
    • Enwright 3rd JF, Kawecki-Crook MA, Voss TC, Schaufele F, Day RN 2003 A PIT-1 homeodomain mutant blocks the intranuclear recruitment of the CCAAT/enhancer binding protein α required for prolactin gene transcription. Mol Endocrinol 17:209-222
    • (2003) Mol Endocrinol , vol.17 , pp. 209-222
    • Enwright III, J.F.1    Kawecki-Crook, M.A.2    Voss, T.C.3    Schaufele, F.4    Day, R.N.5
  • 37
    • 0037340121 scopus 로고    scopus 로고
    • Imaging the localized protein interactions between Pit-1 and the CCAAT/enhancer binding protein α in the living pituitary cell nucleus
    • Day RN, Voss TC, Enwright 3rd JF, Booker CF, Periasamy A, Schaufele F 2003 Imaging the localized protein interactions between Pit-1 and the CCAAT/enhancer binding protein α in the living pituitary cell nucleus. Mol Endocrinol 17:333-345
    • (2003) Mol Endocrinol , vol.17 , pp. 333-345
    • Day, R.N.1    Voss, T.C.2    Enwright III, J.F.3    Booker, C.F.4    Periasamy, A.5    Schaufele, F.6
  • 38
    • 0028117689 scopus 로고
    • The combination of Pit-1 and Pit-1T have a synergistic stimulatory effect on the thyrotropin β-subunit promoter but not the growth hormone or prolactin promoters
    • Haugen BR, Gordon DF, Nelson AR, Wood WM, Ridgway EC 1994 The combination of Pit-1 and Pit-1T have a synergistic stimulatory effect on the thyrotropin β-subunit promoter but not the growth hormone or prolactin promoters. Mol Endocrinol 8:1574-1582
    • (1994) Mol Endocrinol , vol.8 , pp. 1574-1582
    • Haugen, B.R.1    Gordon, D.F.2    Nelson, A.R.3    Wood, W.M.4    Ridgway, E.C.5
  • 39
    • 0029805573 scopus 로고    scopus 로고
    • A 26-amino acid insertion domain defines a functional transcription switch motif in Pit-1β
    • DOI 10.1074/jbc.271.46.28925
    • Diamond SE, Gutierrez-Hartmann A 1996 A 26-amino acid insertion domain defines a functional transcription switch motif in Pit-1β. J Biol Chem 271:28925-28932 (Pubitemid 26382594)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.46 , pp. 28925-28932
    • Diamond, S.E.1    Gutierrez-Hartmann, A.2
  • 40
    • 0032903820 scopus 로고    scopus 로고
    • Reconstitution of the protein kinase a response of the rat prolactin promoter: Differential effects of distinct pit-1 isoforms and functional interaction with oct-1
    • DOI 10.1210/me.13.2.228
    • Diamond SE, Chiono M, Gutierrez-Hartmann A 1999 Reconstitution of the protein kinase A response of the rat prolactin promoter: differential effects of distinct Pit-1 isoforms and functional interaction with Oct-1. Mol Endocrinol 13:228-238 (Pubitemid 29067998)
    • (1999) Molecular Endocrinology , vol.13 , Issue.2 , pp. 228-238
    • Diamond, S.E.1    Chiono, M.2    Gutierrez-Hartmann, A.3
  • 41
    • 0034612884 scopus 로고    scopus 로고
    • The Pit-1β domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter
    • Diamond SE, Gutierrez-Hartmann A 2000 The Pit-1β domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter. J Biol Chem 275:30977-30986 (Pubitemid 30757754)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.40 , pp. 30977-30986
    • Diamond, S.E.1    Gutierrez-Hartmann, A.2
  • 44
    • 0028133254 scopus 로고
    • Ras mediates Src but not epidermal growth factor-receptor tyrosine kinase signaling pathways in GH4 neuroendocrine cells
    • Pickett CA, Gutierrez-Hartmann A 1994 Ras mediates Src but not epidermal growth factor-receptor tyrosine kinase signaling pathways in GH4 neuroendocrine cells. Proc Natl Acad Sci USA 91:8612-8616
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 8612-8616
    • Pickett, C.A.1    Gutierrez-Hartmann, A.2
  • 45
    • 0028941057 scopus 로고
    • Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: Mapping of the essential c-Ets-1 domain
    • Bradford AP, Conrad KE, Wasylyk C, Wasylyk B, Gutierrez-Hartmann A 1995 Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain. Mol Cell Biol 15:2849-2857
    • (1995) Mol Cell Biol , vol.15 , pp. 2849-2857
    • Bradford, A.P.1    Conrad, K.E.2    Wasylyk, C.3    Wasylyk, B.4    Gutierrez-Hartmann, A.5
  • 46
    • 0025277540 scopus 로고
    • Autoregulation of pit-1 gene expression mediated by two cis-active promoter elements
    • DOI 10.1038/346583a0
    • Chen RP, Ingraham HA, Treacy MN, Albert VR, Wilson L, Rosenfeld MG 1990 Autoregulation of pit-1 gene expression mediated by two cis-active promoter elements. Nature 346:583-586 (Pubitemid 20238814)
    • (1990) Nature , vol.346 , Issue.6284 , pp. 583-586
    • Chen, R.1    Ingraham, H.A.2    Treacy, M.N.3    Albert, V.R.4    Wilson, L.5    Rosenfeld, M.G.6
  • 48
    • 0028948238 scopus 로고
    • Mechanisms for flexibility in DNA sequence recognition and VP16-induced complex formation by the Oct-1 POU domain
    • Cleary MA, Herr W 1995 Mechanisms for flexibility in DNA sequence recognition and VP16-induced complex formation by the Oct-1 POU domain. Mol Cell Biol 15:2090-2100
    • (1995) Mol Cell Biol , vol.15 , pp. 2090-2100
    • Cleary, M.A.1    Herr, W.2
  • 49
    • 0031023180 scopus 로고    scopus 로고
    • The Oct-1 POU homeodomain stabilizes the adenovirus preinitiation complex via a direct interaction with the priming protein and is displaced when the replication fork passes
    • DOI 10.1074/jbc.272.6.3398
    • van Leeuwen HC, Rensen M, van der Vliet PC 1997 The Oct-1POU homeodomain stabilizes the adenovirus preinitiation complex via a direct interaction with the priming protein and is displaced when the replication fork passes. J Biol Chem 272:3398-3405 (Pubitemid 27066836)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.6 , pp. 3398-3405
    • Van Leeuwen, H.C.1    Rensen, M.2    Van Der Vliet, P.C.3
  • 51
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 52
    • 0038642016 scopus 로고    scopus 로고
    • Identification and characterization of three new components of the mSin3A corepressor complex
    • Fleischer TC, Yun UJ, Ayer DE 2003 Identification and characterization of three new components of the mSin3A corepressor complex. Mol Cell Biol 23:3456-3467
    • (2003) Mol Cell Biol , vol.23 , pp. 3456-3467
    • Fleischer, T.C.1    Yun, U.J.2    Ayer, D.E.3
  • 53
    • 11144278644 scopus 로고    scopus 로고
    • Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: Involvement of two silencing domains and effect of Ras
    • DOI 10.1128/MCB.25.1.422-431.2005
    • Goeman F, Thormeyer D, Abad M, Serrano M, Schmidt O, Palmero I, Baniahmad A 2005 Growth inhibition by the tumor suppressor p33ING1 in immortalized and primary cells: involvement of two silencing domains and effect of Ras. Mol Cell Biol 25:422-431 (Pubitemid 40039831)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.1 , pp. 422-431
    • Goeman, F.1    Thormeyer, D.2    Abad, M.3    Serrano, M.4    Schmidt, O.5    Palmero, I.6    Baniahmad, A.7
  • 54
    • 0024514598 scopus 로고
    • Analysis of rat prolactin promoter sequences that mediate pituitary-specific and 3',5'-cyclic adenosine monophosphate-regulated gene expression in vivo
    • Keech CA, Gutierrez-Hartmann A 1989 Analysis of rat prolactin promoter sequences that mediate pituitary-specific and 3′,5′-cyclic adenosine monophosphate-regulated gene expression in vivo. Mol Endocrinol 3:832-839 (Pubitemid 19130106)
    • (1989) Molecular Endocrinology , vol.3 , Issue.5 , pp. 832-839
    • Keech, C.A.1    Gutierrez-Hartmann, A.2
  • 55
    • 0026766995 scopus 로고
    • The ras and protein kinase a pathways are mutually antagonistic in regulating rat prolactin promoter activity
    • Conrad KE, Gutierrez-Hartmann A 1992 The ras and protein kinase A pathways are mutually antagonistic in regulating rat prolactin promoter activity. Oncogene 7:1279-1286
    • (1992) Oncogene , vol.7 , pp. 1279-1286
    • Conrad, K.E.1    Gutierrez-Hartmann, A.2


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