PET characteristics of a dedicated breast PET/CT scanner prototype

Physics in Medicine and Biology

Volumn 54, Issue 13, 2009, Pages 4273-4287

  Wu, Yibao ^a   Bowen, Spencer L ^a   Yang, Kai ^a   Packard, Nathan ^a   Fu, Lin ^a   Burkett Jr , George ^b   Qi, Jinyi ^a   Boone, John M ^b   Cherry, Simon R ^a   Badawi, Ramsey D ^b  

^a University of California   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AVERAGE ENERGY; AXIAL FIELD OF VIEWS; CLINICAL TRIAL; COMBINED PET/CT; CRYSTAL BASIS; CYLINDRICAL PHANTOMS; DEAD TIME; FILTERED BACK PROJECTION; FRONT END ELECTRONICS; LINE SOURCES; MAXIMUM A POSTERIORI RECONSTRUCTION; NOISE EQUIVALENT COUNT RATES; PERFORMANCE CHARACTERISTICS; PET DETECTORS; PET SCANNER; PET/CT SCANNERS; POINT SOURCES; SENSITIVITY PROFILES; SPATIAL RESOLUTION; STANDARD DEVIATION; TRANSAXIAL; WHOLE-BODY; X-RAY FLUX;

SCANNING;

IMAGE RESOLUTION;

FLUORODEOXYGLUCOSE F 18;

ARTICLE; BREAST; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CRYSTAL; ELECTRONICS; ENERGY; IMAGE RECONSTRUCTION; INFORMATION PROCESSING; NOISE; OPTICAL RESOLUTION; PERFORMANCE; PHANTOM; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; WHOLE BODY PET; X RAY; BREAST TUMOR; EVALUATION; HUMAN; IMAGE ENHANCEMENT; IMAGE QUALITY; IMAGE SUBTRACTION; INSTRUMENTATION; PILOT STUDY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

BREAST NEOPLASMS; HUMANS; IMAGE ENHANCEMENT; PHANTOMS, IMAGING; PILOT PROJECTS; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SUBTRACTION TECHNIQUE; TOMOGRAPHY, X-RAY COMPUTED;

EID: 69449086352     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/54/13/020     Document Type: Article

References (44)

1. Abreu M C et al 2007 Clear-PEM: a PET imaging system dedicated to breast cancer diagnostics Nucl. Instrum. Methods Phys. Res. A 571 81-4
2. Avril N, Rose C A, Schelling M, Dose J, Kuhn W, Bense S, Weber W, Ziegler S, Graeff H and Schwaiger M 2000 Breast imaging with positron emission tomography and fluorine-18 fluorodeoxyglucose: use and limitations J. Clin. Oncol. 18 3495-502
3. Berg W A et al 2006 High-resolution fluorodeoxyglucose positron emission tomography with compression ('positron emission mammography') is highly accurate in depicting primary breast cancer Breast J. 12 309-23
4. Beyer T and Townsend D W 2006 Putting 'clear' into nuclear medicine: a decade of PET/CT development Eur. J. Nucl. Med. Mol. Imaging 33 857-61
5. Boone J M, Kwan A L C, Seibert J A, Shah N, Lindfors K K and Nelson T R 2005 Technique factors and their relationship to radiation dose in pendant geometry breast CT Med. Phys. 32 3767-76
6. Boone J M, Kwan A L C, Yang K, Burkett G W, Lindfors K K and Nelson T R 2006 Computed tomography for imaging the breast J. Mammary Gland Biol. Neoplasia 11 103-11
7. Bowen S L, Cherry S R, Boone J M and Badawi R D 2006 Monte Carlo simulation study of several camera designs for the PET component of a dedicated breast PET/CT scanner Eur. J. Nucl. Med. Mol. Imaging 33 S117-S
8. Chatziioannou A, Qi J, Moore A, Annala A, Nguyen K, Leahy R and Cherry S R 2000 Comparison of 3D maximum a posteriori and filtered backprojection algorithms for high-resolution animal imaging with microPET IEEE Trans. Med. Imaging 19 507-12
9. Chaudhari A J et al 2008a Multimodality high resolution wrist imaging for monitoring response to therapy in rheumatoid arthritis: instrumentation and techniques Nuclear Science Symp. Conf. Record, 2008 NSS'08 IEEE pp 4840-4
10. Chaudhari A J, Joshi A A, Bowen S L, Leahy R M, Cherry S R and Badawi R D 2008b Crystal identification in positron emission tomography using nonrigid registration to a Fourier-based template Phys. Med. Biol. 53 5011-27
11. Chaudhari A J, Yang Y F, Farrell R, Dokhale P A, Shah K S, Cherry S R and Badawi R D 2008c PSPMT/APD hybrid DOI detectors for the PET component of a dedicated breast PET/CT system-a feasibility study IEEE Trans. Nucl. Sci. 55 853-61
12. Doshi N K, Silverman R W, Shao Y and Cherry S R 2001 maxPET: a dedicated mammary and axillary region PET imaging system for breast cancer IEEE Trans. Nucl. Sci. 48 811-5
13. Eubank W B and Mankoff D A 2005 Evolving role of positron emission tomography in breast cancer imaging Semin. Nucl. Med. 35 84-99
14. Feldkamp L A, Davis L C and Kress J W 1984 Practical cone-beam algorithm J. Opt. Soc. Am. A 1 612-9
15. Jan S et al 2004 GATE: a simulation toolkit for PET and SPECT Phys. Med. Biol. 49 4543-61
16. Judenhofer M S, Pichler B J and Cherry S R 2005 Evaluation of high performance data acquisition boards for simultaneous sampling of fast signals from PET detectors Phys. Med. Biol. 50 29-44
17. Kanazawa T et al 2005 Diagnosis of complete response to neoadjuvant chemotherapy using diagnostic imaging in primary breast cancer patients Breast J. 11 311-6
18. Kitamura K et al 2008 Development of a C-shaped breast PET scanner equipped with four-layer DOI detectors Nuclear Science Symp. Conf. Record, 2008 NSS'08 IEEE pp 5662-5
19. Knoll G F 2000 Radiation Detection and Measurement 3rd edn (New York: Wiley)
20. Kwan A L C, Boone J M, Yang K and Huang S Y 2007 Evaluation of the spatial resolution characteristics of a cone-beam breast CT scanner Med. Phys. 34 275-81 (Pubitemid 46035249)
21. Lamare F, Bowen S L, Visvikis D, Cortes P, Wu Y, Tran V H, Boone J M, Cherry S R and Badawi R D 2005 Design simulation of a rotating dual-headed PET/CT scanner for breast imaging Nuclear Science Symp. Conf. Record, IEEE vol 3 pp 1524-9
22. Levin C S, Foudray A M K, Olcott P D and Habte F 2004 Investigation of position sensitive avalanche photodiodes for a new high-resolution PET detector design IEEE Trans. Nucl. Sci. 51 805-10
23. Li H D, Wong W H, Baghaei H, Uribe J, Wang Y, Zhang Y X, Kim S S, Ramirez R, Liu J G and Liu S T 2007 The engineering and initial results of a transformable low-cost high-resolution PET camera IEEE Trans. Nucl. Sci. 54 1583-8 (Pubitemid 47599129)
24. Linden H M et al 2006 Quantitative fluoroestradiol positron emission tomography imaging predicts response to endocrine treatment in breast cancer J. Clin. Oncol. 24 2793-9
25. Lindfors K K, Boone J M, Nelson T R, Yang K, Kwan A L C and Miller D F 2008 Dedicated breast CT: initial clinical experience Radiology 246 725-33
26. Murthy K, Aznar M, Thompson C J, Loutfi A, Lisbona R and Gagnon J H 2000 Results of preliminary clinical trials of the positron emission mammography system PEM-I: a dedicated breast imaging system producing glucose metabolic images using FDG J. Nucl. Med. 41 1851-8
27. NEMA 2007 Performance Measurements of Positron Emission Tomographs NEMA Standards Publication NU 2-2007
28. Orlov S S 1975 Theory of 3-dimensional reconstruction: 1. Conditions for a full set of projections Kristallografiya 20 511-5
29. Qi J and Leahy R M 2000 Resolution and noise properties of MAP reconstruction for fully 3-D PET IEEE Trans. Med. Imaging 19 493-506
30. Qi J Y, Leahy R M, Cherry S R, Chatziioannou A and Farquhar T H 1998 High-resolution 3D Bayesian image reconstruction using the microPET small-animal scanner Phys. Med. Biol. 43 1001-13
31. Raylman R R et al 2008 The positron emission mammography/tomography breast imaging and biopsy system (PEM/PET): design, construction and phantom-based measurements Phys. Med. Biol. 53 637-53
32. Robar J L, Thompson C J, Murthy K, Clancy R and Bergman A M 1997 Construction and calibration of detectors for high-resolution metabolic breast cancer imaging Nucl. Instrum. Methods Phys. Res. A 392 402-6
33. Rogers J G and Batty C J 2000 Afterglow in LSO and its possible effect on energy resolution IEEE Trans. Nucl. Sci. 47 438-45
34. Rosen E L, Turkington T G, Soo M S, Baker J A and Coleman R E 2005 Detection of primary breast carcinoma with a dedicated, large-field-of-view FDG PET mammography device: initial experience Radiology 234 527-34
35. Strother S C, Casey M E and Hoffman E J 1990 Measuring PET scanner sensitivity-relating countrates to image signal-to-noise ratios using noise equivalent counts IEEE Trans. Nucl. Sci. 37 783-8
36. Tafra L et al 2005 Pilot clinical trial of 18F-fluorodeoxyglucose positron-emission mammography in the surgical management of breast cancer Am. J. Surg. 190 628-32
37. Tai Y-C, Wu H Y and Janecek M 2006 Initial study of an asymmetric PET system dedicated to breast cancer imaging IEEE Trans. Nucl. Sci. 53 121-6
38. Turkington T G, Majewski S, Weisenberger A G, Popov V, Smith M F, Sampson W H, Wojcik R and Kieper D 2002 A large field of view positron emission mammography imager Nuclear Science Symp. Conf. Record, 2003 IEEE vol 3 pp 1883-6
39. Wang G C, Huber J S, Moses W W, Qi J and Choong W S 2006 Characterization of the LBNL PEM camera IEEE Trans. Nucl. Sci. 53 1129-35
40. Watson C C, Casey M E, Bendriem B, Carney J P, Townsend D W, Eberl S, Meikle S and DiFilippo F P 2005 Optimizing injected dose in clinical PET by accurately modeling the counting-rate response functions specific to individual patient scans J. Nucl. Med. 46 1825-34
41. Weinberg I et al 2004 Applications of a PET device with 1.5 mm FWHM intrinsic spatial resolution to breast cancer imaging Biomedical Imaging: Macro to Nano, 2004, IEEE Int. Symp. vol 2 pp 1396-9
42. Wu Y, Yang K, Packard N J, Fu L, Stickel J R, Tran V-H, Qi J, Boone J M, Cherry S R and Badawi R D 2006 Characteristics of the PET component of a dedicated breast PET/CT scanner prototype Nuclear Science Symp. Conf. Record, IEEE vol 4 pp 2335-9
43. Yang Y F, Tai Y C, Siegel S, Newport D F, Bai B, Li Q Z, Leahy R M and Cherry S R 2004 Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging Phys. Med. Biol. 49 2527-45
44. Zhang J, Olcott P D, Chinn G, Foudray A M K and Levin C S 2007 Study of the performance of a novel 1 mm resolution dual-panel PET camera design dedicated to breast cancer imaging using Monte Carlo simulation Med. Phys. 34 689-702