Concerted bis-alkylating reactivity of clerocidin towards unpaired cytosine residues in DNA

Nucleic Acids Research

Volumn 32, Issue 18, 2004, Pages 5658-5667

  Richter, Sara N ^a   Menegazzo, Ileana ^a   Fabris, Daniele ^b   Palumbo, Manlio ^a  

^a UNIVERSITY OF PADOVA   (Italy)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; ANTINEOPLASTIC ANTIBIOTIC; CLEROCIDIN; DNA TOPOISOMERASE (ATP HYDROLYSING); TERPENOID DERIVATIVE; UNCLASSIFIED DRUG; ALKALI; CLEROCIDIN DEOXYCYTOSINE ADDUCT; CLEROCIDIN-DEOXYCYTOSINE ADDUCT; CYTOSINE; DITERPENE; DRUG DERIVATIVE; ENZYME INHIBITOR; EPOXIDE; GUANINE; SINGLE STRANDED DNA;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DNA ALKYLATION; DNA CLEAVAGE; DNA DAMAGE; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY; BASE PAIRING; CHEMISTRY; DNA ADDUCT; DRUG ANTAGONISM; DRUG EFFECT; KINETICS; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE;

ALKALIES; ALKYLATING AGENTS; BASE PAIRING; CYTOSINE; DITERPENES; DNA ADDUCTS; DNA DAMAGE; DNA TOPOISOMERASES, TYPE II, EUKARYOTIC; DNA, SINGLE-STRANDED; ENZYME INHIBITORS; EPOXY COMPOUNDS; GUANINE; KINETICS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

EID: 6944227782     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh898     Document Type: Article

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