Perineural invasion after preoperative chemotherapy predicts poor survival in patients with locally advanced gastric cancer: Gene expression analysis with pathologic validation

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 32, Issue 4, 2009, Pages 356-363

  Jhawer, Minaxi ^a   Coit, Daniel ^b   Brennan, Murray ^b   Qin, Li Xuan ^b   Gonen, Mithat ^b   Klimstra, David ^b   Tang, Laura ^b   Kelsen, David P ^a   Shah, Manish A ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

Gene expression; Hierarchical cluster analysis; Neoadjuvant chemotherapy; Overall survival; Perineural invasion

Indexed keywords

CISPLATIN; FLOXURIDINE; FLUOROURACIL; FOLINIC ACID;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER INVASION; CANCER SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; IMMUNOHISTOCHEMISTRY; METASTASIS; MULTIPLE CYCLE TREATMENT; OVERALL SURVIVAL; PERINEURIUM; PHASE 2 CLINICAL TRIAL; PREDICTION; PREOPERATIVE CARE; PROGNOSIS; STOMACH CANCER; TUMOR RESISTANCE;

ADENOCARCINOMA; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CISPLATIN; COMBINED MODALITY THERAPY; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; FLUOROURACIL; GASTRECTOMY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIERS ESTIMATE; MALE; MAXIMUM TOLERATED DOSE; NEOADJUVANT THERAPY; NEOPLASM INVASIVENESS; NEOPLASM STAGING; PERIPHERAL NERVOUS SYSTEM NEOPLASMS; PREDICTIVE VALUE OF TESTS; PREOPERATIVE CARE; PROBABILITY; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RNA, NEOPLASM; STOMACH NEOPLASMS; SURVIVAL ANALYSIS; TREATMENT OUTCOME;

EID: 69349097831     PISSN: 02773732     EISSN: 1537453X     Source Type: Journal    
DOI: 10.1097/COC.0b013e31818c08e8     Document Type: Article

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