Association of N-type calcium channel autoimmunity in patients with autoimmune autonomic ganglionopathy

Autonomic Neuroscience: Basic and Clinical

Volumn 150, Issue 1-2, 2009, Pages 136-139

  Kimpinski, Kurt ^a   Iodice, Valeria ^a   Vernino, Steve ^b   Sandroni, Paola ^a   Low, Phillip A ^a  

^a MAYO CLINIC   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Autoimmune ganglionopathy; Autonomic failure; Calcium channel antibodies

Indexed keywords

ANTIBODY; CALCIUM CHANNEL N TYPE; CALCIUM CHANNEL N TYPE ANTIBODY; IMMUNOGLOBULIN; MIDODRINE; PYRIDOSTIGMINE; UNCLASSIFIED DRUG;

ADRENERGIC ACTIVITY; ADULT; ARTICLE; AUTOIMMUNE AUTONOMIC GANGLIONOPATHY; AUTOIMMUNE DISEASE; AUTOIMMUNITY; AUTONOMIC DYSFUNCTION; CASE REPORT; DISEASE COURSE; FEMALE; GANGLION; GASTROINTESTINAL DISEASE; HUMAN; MALE; ORTHOSTATIC HYPOTENSION; PRIORITY JOURNAL; SWEATING; VAGUS NERVE STIMULATION;

ADULT; ASSOCIATION; AUTOANTIBODIES; AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM; AUTONOMIC NERVOUS SYSTEM DISEASES; CALCIUM CHANNELS, N-TYPE; FEMALE; GANGLIA, AUTONOMIC; GASTROINTESTINAL DISEASES; HUMANS; HYPOTENSION, ORTHOSTATIC; MALE; MIDDLE AGED; RECEPTORS, NICOTINIC; REFLEX; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX;

EID: 69349095704     PISSN: 15660702     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autneu.2009.06.002     Document Type: Article

References (25)

1. Dhamija R., Tan K.M., Pittock S.J., Foxx-Orenstein A., Benarroch E., and Lennon V.A. Serologic profiles aiding the diagnosis of autoimmune gastrointestinal dysmotility. Clin. Gastroenterol. Hepatol. 6 9 (2008) 988-992
2. Fealey R.D., Low P.A., and Thomas J.E. Thermoregulatory sweating abnormalities in diabetes mellitus. Mayo Clin. Proc. 64 6 (1989) 617-628
3. Gonzalez Burgos G.R., Biali F.I., Cherksey B.D., Sugimori M., Llinás R.R., and Uchitel O.D. Different calcium channels mediate transmitter release evoked by transient or sustained depolarization at mammalian sympathetic ganglia. Neuroscience 64 1 (1995) 117-123
4. Ino M., Yoshinaga T., Wakamori M., Miyamoto N., Takahashi E., Sonoda J., Kagaya T., Oki T., Nagasu T., Nishizawa Y., Tanaka I., Imoto K., Aizawa S., Koch S., Schwartz A., Niidome T., Sawada K., and Mori Y. Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels. Proc. Natl. Acad. Sci. U. S. A. 98 9 (2001) 5323-5328
5. Jobling P., Gibbins I.L., Lewis R.J., and Morris J.L. Differential expression of calcium channels in sympathetic and parasympathetic preganglionic inputs to neurons in paracervical ganglia of guinea-pigs. Neuroscience 127 2 (2004) 455-466
6. Klein C.M., Vernino S., Lennon V.A., Sandroni P., Fealey R.D., Benrud-Larson L., Sletten D., and Low P.A. The spectrum of autoimmune autonomic neuropathies. Ann. Neurol. 53 6 (2003) 752-758
7. Lennon V.A., Kryzer T.J., Griesmann G.E., O Suilleabhain P.E., Windebank A.J., Woppmann A., Miljanich G.P., and Lambert E.H. Calcium-channel antibodies in the Lambert-Eaton syndrome and other paraneoplastic syndromes. N. Engl. J. Med. 332 22 (1995) 1467-1474
8. Lennon V.A., Ermilov L.G., Szurszewski J.H., and Vernino S. Immunisation with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease. J. Clin. Invest. 111 6 (2003) 907-913
9. Low P.A. Composite autonomic scoring scale for laboratory quantification of generalized autonomic failure. Mayo Clin. Proc. 68 8 (1993) 748-752
10. Low P.A. Testing the autonomic nervous system. Semin. Neurol. 23 4 (2003) 407-421
11. Low P.A., and Opfer-Gehrking T.L. The autonomic laboratory. Am. J. Electroneurodgn. Technol. 39 2 (1999) 65-76
12. Low P.A., Denq J.C., Opfer-Gehrking T.L., Dyck P.J., O Brien P.C., and Slezak J.M. Effect of age and gender on sudomotor and cardiovagal function and blood pressure response to tilt in normal subjects. Muscle Nerve 20 12 (1997) 1561-1568
13. McKeon A., Lennon V.A., Jacob A., Matiello M., Lucchinetti C.F., Kale N., Chan K.H., Weinshenker B.G., Apiwattinakul M., Wingerchuk D.M., and Pittock S.J. Coexistence of myasthenia gravis and serological markers of neurological autoimmunity in neuromyelitis optica. Muscle Nerve 39 1 (2009) 87-90
14. Monstad S.E., Drivsholm L., Storstein A., Aarseth J.H., Haugen M., Lang B., Vincent A., and Vedeler C.A. Hu and voltage-gated calcium channel (VGCC) antibodies related to the prognosis of small-cell lung cancer. J. Clin. Oncol. 22 5 (2004) 795-800
15. Motomura M., Lang B., Johnston I., Palace J., Vincent A., and Newsom-Davis J. Incidence of serum anti-P/O-type and anti-N-type calcium channel autoantibodies in the Lambert-Eaton myasthenic syndrome. J. Neurol. Sci. 147 1 (1997) 35-42
16. O Suilleabhain P., Low P.A., and Lennon V.A. Autonomic dysfunction in the Lambert-Eaton myasthenic syndrome: serologic and clinical correlates. Neurology 50 1 (1998) 88-93
17. Pasha S.F., Lunsford T.N., and Lennon V.A. Autoimmune gastrointestinal dysmotility treated successfully with pyridostigmine. Gastroenterology 131 5 (2006) 1592-1596
18. Pittock S.J., Lucchinetti C.F., and Lennon V.A. Anti-neuronal nuclear autoantibody type 2: paraneoplastic accompaniments. Ann. Neurol. 53 5 (2003) 580-597
19. Pruneau D., and Bélichard P. Haemodynamic and humoral effects of omega-conotoxin GVIA in normotensive and spontaneously hypertensive rats. Eur. J. Pharmacol. 211 3 (1992) 329-335
20. Sandroni P., Vernino S., Klein C.M., Lennon V.A., Benrud-Larson L., Sletten D., and Low P.A. Idiopathic autonomic neuropathy: comparison of cases seropositive and seronegative for ganglionic acetylcholine receptor antibody. Arch. Neurol. 61 1 (2004) 44-48
21. Suarez G.A., Fealey R.D., Camilleri M., and Low P.A. Idiopathic autonomic neuropathy: clinical, neurophysiologic, and follow-up studies on 27 patients. Neurology 44 9 (1994) 1675-1682
22. Vernino S., and Lennon V.A. Neuronal ganglionic acetylcholine receptor autoimmunity. Ann. NY Acad. Sci. 998 (2003) 211-214
23. Vernino S., Low P.A., and Lennon V.A. Experimental autoimmune autonomic neuropathy. J. Neurophysiol. 90 3 (2003) 2053-2059
24. Vernino S., Ermilov L.G., Sha L., Szurszewski J.H., Low P.A., and Lennon V.A. Passive transfer of autoimmune autonomic neuropathy to mice. J. Neurosci. 24 32 (2004) 7037-7042
25. Vernino S., Sandroni P., Singer W., and Low P.A. Autonomic ganglia: target and novel therapeutic tool. Neurology. 70 20 (2008) 1926-1932