Passive transfer of autoimmune autonomic neuropathy to mice

Journal of Neuroscience

Volumn 24, Issue 32, 2004, Pages 7037-7042

  Vernino, Steven ^a,c   Ermilov, Leonid G ^a   Sha, Lei ^a   Szurszewski, Joseph H ^a   Low, Phillip A ^a   Lennon, Vanda A ^a,b  

^a Mayo Clinic   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c MAYO CLINIC   (United States)

Author keywords

Electrophysiology; Gastrointestinal dysmotility; Neuronal nicotinic acetylcholine receptor; Parasympathetic; Pupil; Sympathetic

Indexed keywords

CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR ANTIBODY; HYBRID PROTEIN; IMMUNOGLOBULIN G; NICOTINIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY BLOOD LEVEL; ARTICLE; AUTOIMMUNE AUTONOMIC NEUROPATHY; AUTOIMMUNE DISEASE; AUTONOMIC DYSFUNCTION; AUTONOMIC GANGLION; AUTONOMIC NEUROPATHY; BRADYCARDIA; CATECHOLAMINE RELEASE; CONTROLLED STUDY; DIGESTIVE SYSTEM FUNCTION DISORDER; DYSAUTONOMIA; ELECTROPHYSIOLOGY; HUMAN; IMMUNOGLOBULIN PRODUCTION; IMMUNOMODULATION; MALE; MOUSE; MYDRIASIS; NONHUMAN; PASSIVE TRANSPORT; PATHOGENESIS; PRIORITY JOURNAL; RABBIT; SYNAPTIC TRANSMISSION; URINE RETENTION;

ANIMALS; AUTOANTIBODIES; AUTONOMIC NERVOUS SYSTEM DISEASES; CATECHOLAMINES; DISEASE MODELS, ANIMAL; GANGLIA, AUTONOMIC; GASTROINTESTINAL MOTILITY; HEART RATE; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULIN G; MALE; MESENTERY; MICE; MICE, INBRED BALB C; MIOSIS; NEURITIS, AUTOIMMUNE, EXPERIMENTAL; RABBITS; RECEPTORS, NICOTINIC; RECOMBINANT FUSION PROTEINS; SYNAPTIC TRANSMISSION; URINARY RETENTION;

EID: 4143059281     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1485-04.2004     Document Type: Article

References (25)

1. Bennett MR (1994) Nitric oxide release and long term potentiation at synapses in autonomic ganglia. Gen Pharmacol 25:1541-1551.
2. Briggs CA, McAfee DA (1988) Long-term potentiation at nicotinic synapses in the rat superior cervical ganglion. J Physiol (Lond) 404:129-144.
3. Drachman DB, Angus CW, Adams RN, Michelson JD, Hoffman GJ (1978) Myasthenic antibodies cross-link acetylcholine receptors to accelerate degradation. N Engl J Med 298:1116-1122.
4. Fukunaga H, Engel AG, Lang B, Newsom-Davis J, Vincent A (1983) Passive transfer of Lambert-Eaton myasthenic syndrome with IgG from man to mouse depletes the presynaptic membrane active zones. Proc Natl Acad Sci USA 80:7636-7640.
5. Klein CM, Vernino S, Lennon VA, Sandroni P, Fealey RD, Benrud-Larson L, Sletten D, Low PA (2003) The spectrum of autoimmune autonomic neuropathies. Ann Neurol 53:752-758.
6. Lambert EH, Lennon VA (1988) Selected IgG rapidly induces Lambert-Eaton myasthenic syndrome in mice: complement independence and EMG abnormalities. Muscle Nerve 11:1133-1145.
7. Lang B, Newsom-Davis J, Wray D, Vincent A, Murray N (1981) Autoimmune aetiology for myasthenic (Eaton-Lambert) syndrome. Lancet 2:224-226.
8. Lennon VA (1977) Immunofluorescence analysis of surface acetylcholine receptors on muscle: modulation by auto-antibodies. In: Cholinergic mechanisms and psychopharmacology (DJ Jenden, ed), pp 77-91. New York: Plenum.
9. Lennon VA, Griesmann GE (1989) Evidence against acetylcholine receptor having a main immunogenic region as target for autoantibodies in myasthenia gravis. Neurology 39:1069-1076.
10. Lennon VA, Lambert EH (1980) Myasthenia gravis induced by monoclonal antibodies to acetylcholine receptors. Nature 285:238-240.
11. Lennon VA, Lindstrom JM, Seybold ME (1975) Experimental autoimmune myasthenia: a model of myasthenia gravis in rats and guinea pigs. J Exp Med 141:1365-1375.
12. Lennon VA, Ermilov LG, Szurszewski JH, Vernino S (2003) Immunization with neuronal nicotinic acetylcholine receptor induces neurological autoimmune disease. J Clin Invest 111:907-913.
13. Lindstrom JM, Engel AG, Seybold ME, Lennon VA, Lambert EH (1976) Pathological mechanisms in experimental autoimmune myasthenia gravis. II. Passive transfer of experimental autoimmune myasthenia gravis in rats with anti-acetylcholine receptor antibodies. J Exp Med 144:739-753.
14. Miller S, Szurszewski J (1997) Colonic mechanosensory afferent input to neurons in the mouse superior mesenteric ganglion. Am J Physiol 272:G357-G366.
15. Patrick J, Lindstrom J (1973) Autoimmune response to acetylcholine receptors. Science 180:871-872.
16. Patrick J, Seguela P, Vernino S, Amador M, Luetje C, Dani J (1993) Functional diversity of neuronal nicotinic acetylcholine receptors. In: Progress in brain research (Cuello AC, ed), pp 113-120. Amsterdam: Elsevier.
17. Sahul Z, Black J, Shen W (2002) Accurate QRS detection at times of high artifact during tilt table testing. Clin Auton Res 12:329.
18. Suarez GA, Fealey RD, Camilleri M, Low PA (1994) Idiopathic autonomic neuropathy: clinical, neurophysiologic, and follow-up studies on 27 patients. Neurology 44:1675-1682.
19. Toyka KV, Drachman DB, Griffin DE, Pestronk A, Winkelstein JA, Fishbeck KH, Kao I (1977) Myasthenia gravis. Study of humoral immune mechanisms by passive transfer to mice. N Engl J Med 296:125-131.
20. Tuininga YS, Crijns HJ, Brouwer J, van den Berg MP, Man in't Veld AJ, Mulder G, Lie KI (1995) Evaluation of importance of central effects of atenolol and metoprolol measured by heart rate variability during mental performance tasks, physical exercise, and daily life in stable postinfarct patients. Circulation 92:3415-3423.
21. Vernino S, Adamski J, Kryzer TJ, Fealey RD, Lennon VA (1998) Neuronal nicotinic ACh receptor antibody in subacute autonomic neuropathy and cancer-related syndromes. Neurology 50:1806-1813.
22. Vernino S, Low PA, Fealey RD, Stewart JD, Farrugia G, Lennon VA (2000) Autoantibodies to ganglionic acetylcholine receptors in autoimmune autonomic neuropathies. N Engl J Med 343:847-855.
23. Vernino S, Kryzer T, Lennon V (2002) Autoantibodies in autoimmune autonomic neuropathies and neuromuscular hyperexcitability disorders. In: Manual of clinical laboratory immunology (Rose N, Hamilton R, Detrick B, eds), pp 1013-1017. Washington, DC: ASM.
24. Vernino S, Low PA, Lennon VA (2003) Experimental autoimmune autonomic neuropathy. J Neurophysiol 90:2053-2059.
25. Xu W, Gelber S, Orr-Urtreger A, Armstrong D, Lewis RA, Ou CN, Patrick J, Role L, De Biasi M, Beaudet AL (1999) Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor. Proc Natl Acad Sci USA 96:5746-5751.