Innate immune responses to Encephalitozoon species infections

Microbes and Infection

Volumn 11, Issue 12, 2009, Pages 905-911

  Mathews, Amber ^a   Hotard, Anne ^a   Hale Donze, Hollie ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

Dendritic cells; Encephalitozoon; Innate immunity; Macrophage; Microsporidia

Indexed keywords

CYTOKINE PRODUCTION; DENDRITIC CELL; ENCEPHALITOZOON; HUMAN; IMMUNE RESPONSE; INFECTION RESISTANCE; INNATE IMMUNITY; LIFE CYCLE; MACROPHAGE ACTIVATION; MICROSPORIDA; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTOZOAL INFECTION; PROTOZOAN SPORE; SHORT SURVEY; TH1 CELL;

ANIMALS; DENDRITIC CELLS; ENCEPHALITOZOON; ENCEPHALITOZOONOSIS; HUMANS; IMMUNITY, INNATE; MACROPHAGES;

ENCEPHALITOZOON; EUKARYOTA; FUNGI; MICROSPORIDIA;

EID: 69249239133     PISSN: 12864579     EISSN: 1769714X     Source Type: Journal    
DOI: 10.1016/j.micinf.2009.06.004     Document Type: Short Survey

References (49)

1. Monaghan S.R., Kent M.L., Watral V.G., Kaufman R.J., Lee L.E., and Bols N.C. Animal cell cultures in microsporidial research: their general roles and their specific use for fish microsporidia. In Vitro Cell Dev. Biol. Anim. 45 (2009) 135-147
2. Didier E.S., Stovall M.E., Green L.C., Brindley P.J., Sestak K., and Didier P.J. Epidemiology of microsporidiosis: sources and modes of transmission. Vet. Parasitol. 126 (2004) 145-166
3. H. Hale-Donze, E. Didier, Microsporidioses, Encyclopedia of Life Sciences, 2007.
4. Didier E.S. Microsporidiosis: an emerging and opportunistic infection in humans and animals. Acta Trop. 94 (2005) 61-76
5. Vavra J., and Larsson J.I.R. Structure of the microsporidia. In: Wittner M., and Weiss L.M. (Eds). The microsporidia and microsporidiosis (1999), ASM Press, Washington, D.C. 7-84
6. Findley A.M., Weidner E.H., Carman K.R., Xu Z., and Godbar J.S. Role of the posterior vacuole in Spraguea lophii (Microsporidia) spore hatching. Folia Parasitol (Praha) 52 (2005) 111-117
7. Cali A., and Takvorian P.M. Developmental morphology and life cycles of the microsporidia. In: Wittner M., and Weiss L.M. (Eds). The microsporidia and microsporidiosis (1999), ASM Press, Washington, D.C. 85-128
8. Orenstein J.M. Diagnostic pathology of microsporidiosis. Ultrastruct. Pathol. 27 (2003) 141-149
9. Mathis A., Weber R., and Deplazes P. Zoonotic potential of the microsporidia. Clin. Microbiol. Rev. 18 (2005) 423-445
10. Nkinin S.W., Asonganyi T., Didier E.S., and Kaneshiro E.S. Microsporidian infection is prevalent in healthy people in Cameroon. J. Clin. Microbiol. 45 (2007) 2841-2846
11. Das S., Sharma S., Sahu S.K., Nayak S.S., and Kar S. New microbial spectrum of epidemic keratoconjunctivitis: clinical and laboratory aspects of an outbreak. Br. J. Ophthalmol. 92 (2008) 861-862
12. Didier E.S., Didier P.J., Snowden K.F., and Shadduck J.A. Microsporidiosis in mammals. Microbes Infect./Institut Pasteur 2 (2000) 709-720
13. Khan I.A., Moretto M., and Weiss L.M. Immune response to Encephalitozoon cuniculi infection. Microbes Infect 3 (2001) 401-405
14. Khan I.A., and Didier E.S. Insights into the immune responses to microsporidia (2004), Kluwer Acad. Pubs, Boston
15. Franzen C., Hosl M., Salzberger B., and Hartmann P. Uptake of Encephalitozoon spp. and Vittaforma corneae (Microsporidia) by different cells. J. Parasitol. 91 (2005) 745-749
16. Snowden K., Logan K., and Didier E.S. Encephalitozoon cuniculi strain III is a cause of encephalitozoonosis in both humans and dogs. J. Infect. Dis. 180 (1999) 2086-2088
17. Pozio E., and Morales M.A. The impact of HIV-protease inhibitors on opportunistic parasites. Trends Parasitol. 21 (2005) 58-63
18. Goguel J., Katlama C., Sarfati C., Maslo C., Leport C., and Molina J.M. Remission of AIDS-associated intestinal microsporidiosis with highly active antiretroviral therapy. Aids 11 (1997) 1658-1659
19. Khan I.A., Schwartzman J.D., Kasper L.H., and Moretto M. CD8+ CTLs are essential for protective immunity against Encephalitozoon cuniculi infection. J. Immunol. 162 (1999) 6086-6091
20. Wei S., Daniel B.J., Brumlik M.J., Burow M.E., Zou W., Khan I.A., Wadsworth S., Siekierka J., and Curiel T.J. Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection. Antimicrob. Agents Chemother. 51 (2007) 4324-4328
21. Khan I.A., and Didier E.S. Insights into the immune microsporidia (2004), Kluwer Acad, Pubs, Boston
22. Braunfuchsova P., Kopecky J., Ditrich O., and Koudela B. Cytokine response to infection with the microsporidian, Encephalitozoon cuniculi. Folia Parasitol. (Praha) 46 (1999) 91-95
23. Moretto M., Weiss L.M., and Khan I.A. Induction of a rapid and strong antigen-specific intraepithelial lymphocyte response during oral Encephalitozoon cuniculi infection. J. Immunol. 172 (2004) 4402-4409
24. El Fakhry Y., Achbarou A., Desportes I., and Mazier D. Resistance to Encephalitozoon intestinalis is associated with interferon-gamma and interleukin-2 cytokines in infected mice. Parasite Immunol. 23 (2001) 297-303
25. Janeway Jr. C.A. How the immune system works to protect the host from infection: a personal view. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 7461-7468
26. Vasselon T., and Detmers P.A. Toll receptors: a central element in innate immune responses. Infect. Immun. 70 (2002) 1033-1041
27. Tailor P., Tamura T., and Ozato K. IRF family proteins and type I interferon induction in dendritic cells. Cell Res. 16 (2006) 134-140
28. Sebastian C., Espia M., Serra M., Celada A., and Lloberas J. MacrophAging: a cellular and molecular review. Immunobiology 210 (2005) 121-126
29. Franzen C. Microsporidia: how can they invade other cells?. Trends Parasitolo. 20 (2004) 275-279
30. Couzinet S., Cejas E., Schittny J., Deplazes P., Weber R., and Zimmerli S. Phagocytic uptake of Encephalitozoon cuniculi by nonprofessional phagocytes. Infect. Immun. 68 (2000) 6939-6945
31. Franzen C., Muller A., Hartmann P., and Salzberger B. Cell invasion and intracellular fate of Encephalitozoon cuniculi (Microsporidia). Parasitology 130 (2005) 285-292
32. Fischer J., Tran D., Juneau R., and Hale-Donze H. Kinetics of Encephalitozoon spp. infection of human macrophages. J. Parasitol. 94 (2008) 169-175
33. Franzen C., Hartmann P., and Salzberger B. Cytokine and nitric oxide responses of monocyte-derived human macrophages to microsporidian spores. Experiment. Parasitol. 109 (2005) 1-6
34. Didier E.S., and Shadduck J.A. IFN-gamma and LPS induce murine macrophages to kill Encephalitozoon cuniculi in vitro. J. Eukaryot. Microbiol. 41 (1994) 34S
35. Southern T.R., Jolly C.E., Lester M.E., and Hayman J.R. EnP1, a microsporidian spore wall protein that enables spores to adhere to and infect host cells in vitro. Eukaryot. Cell 6 (2007) 1354-1362
36. Taupin V., Garenaux E., Mazet M., Maes E., Denise H., Prensier G., Vivares C.P., Guerardel Y., and Metenier G. Major O-glycans in the spores of two microsporidian parasites are represented by unbranched manno-oligosaccharides containing alpha-1,2 linkages. Glycobiology 17 (2007) 56-67
37. Medzhitov R., Preston-Hurlburt P., and Janeway Jr. C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 (1997) 394-397
38. Netea M.G., Van der Meer J.W., and Kullberg B.J. Toll-like receptors as an escape mechanism from the host defense. Trends Microbiol. 12 (2004) 484-488
39. Akira S. Toll-like receptor signaling. J. Biol. Chem. 278 (2003) 38105-38108
40. Fischer J., Suire C., and Hale-Donze H. Toll-like receptor 2 recognition of the microsporidia Encephalitozoon spp. induces nuclear translocation of NF-kappaB and subsequent inflammatory responses. Infect. Immun. 76 (2008) 4737-4744
41. van de Veerdonk F.L., Kullberg B.J., van der Meer J.W., Gow N.A., and Netea M.G. Host-microbe interactions: innate pattern recognition of fungal pathogens. Curr. Opin. Microbiol. 11 (2008) 305-312
42. Fischer J., West J., Agochukwu N., Suire C., and Hale-Donze H. Induction of host chemotactic response by Encephalitozoon spp. Infect. Immun. 75 (2007) 1619-1625
43. Mellman I., and Steinman R.M. Dendritic cells: specialized and regulated antigen processing machines. Cell 106 (2001) 255-258
44. Moretto M.M., Weiss L.M., Combe C.L., and Khan I.A. IFN-gamma-producing dendritic cells are important for priming of gut intraepithelial lymphocyte response against intracellular parasitic infection. J. Immunol. 179 (2007) 2485-2492
45. Moretto M.M., Lawlor E.M., and Khan I.A. Aging mice exhibit a functional defect in mucosal dendritic cell response against an intracellular pathogen. J. Immunol. 181 (2008) 7977-7984
46. Gunnarsson G., Hurlbut D., DeGirolami P.C., Federman M., and Wanke C. Multiorgan microsporidiosis: report of five cases and review. Clin. Infect. Dis. 21 (1995) 37-44
47. Carlson J.R., Li L., Helton C.L., Munn R.J., Wasson K., Perez R.V., Gallay B.J., and Finkbeiner W.E. Disseminated microsporidiosis in a pancreas/kidney transplant recipient. Archiv. Pathol. Lab. Med. 128 (2004) e41-e43
48. Leitch G.J., Ward T.L., Shaw A.P., and Newman G. Apical spore phagocytosis is not a significant route of infection of differentiated enterocytes by Encephalitozoon intestinalis. Infect. Immun. 73 (2005) 7697-7704
49. Leitch G.J., and Ceballos C. A role for antimicrobial peptides in intestinal microsporidiosis. Parasitology 136 (2009) 175-181