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Volumn 39, Issue 3, 2009, Pages 274-281

Significance of dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expressions in hepatocellular carcinoma

Author keywords

Dihydropyrimidine dehydrogenase; Hepatic resection; Hepatocellular carcinoma; Ki 67; Prognosis; Thymidylate synthase

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; KI 67 ANTIGEN; MESSENGER RNA; THYMIDYLATE SYNTHASE;

EID: 69249236864     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2008.00457.x     Document Type: Article
Times cited : (10)

References (39)
  • 1
    • 0026576723 scopus 로고
    • Hepatocellular carcinoma: Recent progress
    • Okuda K. Hepatocellular carcinoma: Recent progress. Hepatology 1992; 15: 948-63.
    • (1992) Hepatology , vol.15 , pp. 948-963
    • Okuda, K.1
  • 2
    • 18144411666 scopus 로고    scopus 로고
    • Updated treatment approach to hepatocellular carcinoma
    • Llovet JM. Updated treatment approach to hepatocellular carcinoma. J Gastroenterol 2005; 40: 225-35.
    • (2005) J Gastroenterol , vol.40 , pp. 225-235
    • Llovet, J.M.1
  • 3
    • 49649124981 scopus 로고    scopus 로고
    • Combined intra-arterial 5-fluorouracil and subcutaneous interferon-alpha therapy for highly advanced hepatocellular carcinoma
    • Damdinsuren B, Nagano H, Monden M. Combined intra-arterial 5-fluorouracil and subcutaneous interferon-alpha therapy for highly advanced hepatocellular carcinoma. Hepatol Res 2007; 37: 238-50.
    • (2007) Hepatol Res , vol.37 , pp. 238-250
    • Damdinsuren, B.1    Nagano, H.2    Monden, M.3
  • 4
    • 4043181366 scopus 로고    scopus 로고
    • Clinicopathologic analysis of risk factors for distant metastasis of hepatocellular carcinoma
    • Ogawa M, Yamamoto T, Kubo S et al. Clinicopathologic analysis of risk factors for distant metastasis of hepatocellular carcinoma. Hepatol Res 2004; 29: 228-34.
    • (2004) Hepatol Res , vol.29 , pp. 228-234
    • Ogawa, M.1    Yamamoto, T.2    Kubo, S.3
  • 5
    • 33947154931 scopus 로고    scopus 로고
    • Effects of lamivudine on outcome after liver resection for hepatocellular carcinoma in patients with active replication of hepatitis B virus
    • Kubo S, Tanaka H, Takemura S et al. Effects of lamivudine on outcome after liver resection for hepatocellular carcinoma in patients with active replication of hepatitis B virus. Hepatol Res 2007; 37: 94-100.
    • (2007) Hepatol Res , vol.37 , pp. 94-100
    • Kubo, S.1    Tanaka, H.2    Takemura, S.3
  • 6
    • 34447335306 scopus 로고    scopus 로고
    • Report of the 17th nationwide follow-up survey of primary liver cancer in Japan
    • Ikai I, Arii S, Okazaki M et al. Report of the 17th nationwide follow-up survey of primary liver cancer in Japan. Hepatol Res 2007; 37: 676-91.
    • (2007) Hepatol Res , vol.37 , pp. 676-691
    • Ikai, I.1    Arii, S.2    Okazaki, M.3
  • 7
    • 0032748608 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase: Its role in 5-fluorouracil clinical toxicity and tumor resistance
    • Diasio RB, Johnson MR. Dihydropyrimidine dehydrogenase: Its role in 5-fluorouracil clinical toxicity and tumor resistance. Clin Cancer Res 1999; 5: 1947-9.
    • (1999) Clin Cancer Res , vol.5 , pp. 1947-1949
    • Diasio, R.B.1    Johnson, M.R.2
  • 8
    • 0141455146 scopus 로고    scopus 로고
    • Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: Predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil
    • Kornmann M, Schwabe W, Sander S et al. Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: Predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil. Clin Cancer Res 2003; 15: 4116-24.
    • (2003) Clin Cancer Res , vol.15 , pp. 4116-4124
    • Kornmann, M.1    Schwabe, W.2    Sander, S.3
  • 9
    • 0023187085 scopus 로고
    • Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile
    • Heggie GD, Sommadossi JP, Cross DS, Huster WJ, Diasio RB. Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile. Cancer Res 1987; 47: 2203-6.
    • (1987) Cancer Res , vol.47 , pp. 2203-2206
    • Heggie, G.D.1    Sommadossi, J.P.2    Cross, D.S.3    Huster, W.J.4    Diasio, R.B.5
  • 10
    • 33244468377 scopus 로고    scopus 로고
    • Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors -correlation to tumor histopathology and clinical follow-up
    • Lassmann S, Hennig M, Rosenberg R et al. Thymidine phosphorylase, dihydropyrimidine dehydrogenase and thymidylate synthase mRNA expression in primary colorectal tumors -correlation to tumor histopathology and clinical follow-up. Int J Colorectal Dis 2006; 21: 238-47.
    • (2006) Int J Colorectal Dis , vol.21 , pp. 238-247
    • Lassmann, S.1    Hennig, M.2    Rosenberg, R.3
  • 11
    • 0034548797 scopus 로고    scopus 로고
    • Gene expression for dihydropyrimidine dehydrogenase influences outcome in epithelial ovarian cancer
    • Fujiwaki R, Hata K, Nakayama K, Fukumoto M, Miyazaki K. Gene expression for dihydropyrimidine dehydrogenase influences outcome in epithelial ovarian cancer. J Clin Oncol 2000; 18: 3946-51.
    • (2000) J Clin Oncol , vol.18 , pp. 3946-3951
    • Fujiwaki, R.1    Hata, K.2    Nakayama, K.3    Fukumoto, M.4    Miyazaki, K.5
  • 12
    • 0015962412 scopus 로고
    • Mechanism of interaction of thymidylate synthase with 5-fluorodeoxyuridine
    • Santini DV, McHenry CS, Sommer H. Mechanism of interaction of thymidylate synthase with 5-fluorodeoxyuridine. Biochemistry 1974; 13: 471-80.
    • (1974) Biochemistry , vol.13 , pp. 471-480
    • Santini, D.V.1    McHenry, C.S.2    Sommer, H.3
  • 13
    • 33749587054 scopus 로고    scopus 로고
    • Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase
    • Ceppi P, Volante M, Saviozzi S et al. Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase. Cancer 2006; 107: 1589-96.
    • (2006) Cancer , vol.107 , pp. 1589-1596
    • Ceppi, P.1    Volante, M.2    Saviozzi, S.3
  • 14
    • 16544363876 scopus 로고    scopus 로고
    • Thymidine phosphate and dihydropyrimidine dehydrogenase expression in hepatocellular carcinoma and metastatic liver cancer
    • Hotta T, Kobayashi Y, Taniguchi K et al. Thymidine phosphate and dihydropyrimidine dehydrogenase expression in hepatocellular carcinoma and metastatic liver cancer. Oncol Rep 2004; 12: 347-51.
    • (2004) Oncol Rep , vol.12 , pp. 347-351
    • Hotta, T.1    Kobayashi, Y.2    Taniguchi, K.3
  • 15
    • 0345375543 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase and thymidylate synthase activities in hepatocellular carcinomas and in diseased livers
    • Baba H, Teramoto K, Kawamura T, Mori A, Imamura M, Arii S. Dihydropyrimidine dehydrogenase and thymidylate synthase activities in hepatocellular carcinomas and in diseased livers. Cancer Chemother Pharmacol 2003; 52: 469-76.
    • (2003) Cancer Chemother Pharmacol , vol.52 , pp. 469-476
    • Baba, H.1    Teramoto, K.2    Kawamura, T.3    Mori, A.4    Imamura, M.5    Arii, S.6
  • 16
    • 35948943907 scopus 로고    scopus 로고
    • Profiling of fluorouracil-related genes by microdissection technique in hepatocellular carcinoma
    • Takahashi T, Yoshida H, Mamada Y et al. Profiling of fluorouracil-related genes by microdissection technique in hepatocellular carcinoma. Hepatogastroenterology 2007; 54: 1612-6.
    • (2007) Hepatogastroenterology , vol.54 , pp. 1612-1616
    • Takahashi, T.1    Yoshida, H.2    Mamada, Y.3
  • 18
    • 0034146097 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence
    • Lord RV, Salonga D, Danenberg KD et al. Telomerase reverse transcriptase expression is increased early in the Barrett's metaplasia, dysplasia, adenocarcinoma sequence. J Gastrointest Surg 2000; 4: 135-42.
    • (2000) J Gastrointest Surg , vol.4 , pp. 135-142
    • Lord, R.V.1    Salonga, D.2    Danenberg, K.D.3
  • 20
    • 0029964835 scopus 로고    scopus 로고
    • A novel method for real time quantitative RT-PCR
    • Gibson UE, Heid CA, Williams PM. A novel method for real time quantitative RT-PCR. Genome Res 1996; 6: 995-1011.
    • (1996) Genome Res , vol.6 , pp. 995-1011
    • Gibson, U.E.1    Heid, C.A.2    Williams, P.M.3
  • 21
    • 37848999146 scopus 로고    scopus 로고
    • Relationship between survivin expression and recurrence, and prognosis in hepatocellular carcinoma
    • Ye CP, Qiu CZ, Huang ZX et al. Relationship between survivin expression and recurrence, and prognosis in hepatocellular carcinoma. World J Gastroenterl 2007; 13: 6264-8.
    • (2007) World J Gastroenterl , vol.13 , pp. 6264-6268
    • Ye, C.P.1    Qiu, C.Z.2    Huang, Z.X.3
  • 22
    • 16544386812 scopus 로고    scopus 로고
    • Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers
    • Hotta T, Taniguchi K, Kobayashi Y et al. Comparative analysis of thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in gastric and colorectal cancers. Oncol Rep 2004; 11: 1045-51.
    • (2004) Oncol Rep , vol.11 , pp. 1045-1051
    • Hotta, T.1    Taniguchi, K.2    Kobayashi, Y.3
  • 23
    • 21644467500 scopus 로고    scopus 로고
    • Thymidylate synthase predicts for clinical outcome in invasive breast cancer
    • Yu Z, Sun J, Zhen J, Zhang Q, Yang Q. Thymidylate synthase predicts for clinical outcome in invasive breast cancer. Histol Histopathol 2005; 20: 871-8.
    • (2005) Histol Histopathol , vol.20 , pp. 871-878
    • Yu, Z.1    Sun, J.2    Zhen, J.3    Zhang, Q.4    Yang, Q.5
  • 24
    • 0032862086 scopus 로고    scopus 로고
    • Regulation of dihydropyrimidine dehydrogenase in colorectal cancer
    • Johnson SJ, Ridge SA, Cassidy J, McLeod HL. Regulation of dihydropyrimidine dehydrogenase in colorectal cancer. Clin Cancer Res 1999; 5: 2566-70.
    • (1999) Clin Cancer Res , vol.5 , pp. 2566-2570
    • Johnson, S.J.1    Ridge, S.A.2    Cassidy, J.3    McLeod, H.L.4
  • 25
    • 0014039635 scopus 로고
    • Cancer chemotherapy with purine and pyrimidine analogues
    • Heidelberger C. Cancer chemotherapy with purine and pyrimidine analogues. Annu Rev Pharm 1967; 7: 101-24.
    • (1967) Annu Rev Pharm , vol.7 , pp. 101-124
    • Heidelberger, C.1
  • 26
    • 0031825090 scopus 로고    scopus 로고
    • Natural course of small hepatocellular carcinoma with underlying cirrhosis. A study of 3 0 patients
    • Ebara M, Hatano R, Fukuda H, Yoshikawa M, Sugiura N, Saisho H. Natural course of small hepatocellular carcinoma with underlying cirrhosis. A study of 3 0 patients. Hepatogastroenterology 1998; 3: 1214-20.
    • (1998) Hepatogastroenterology , vol.3 , pp. 1214-1220
    • Ebara, M.1    Hatano, R.2    Fukuda, H.3    Yoshikawa, M.4    Sugiura, N.5    Saisho, H.6
  • 27
    • 34548049941 scopus 로고    scopus 로고
    • Regulation of genes of the circadian clock in human colon cancer: Reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors
    • Krugluger W, Brandstaetter A, Kallay E et al. Regulation of genes of the circadian clock in human colon cancer: Reduced period-1 and dihydropyrimidine dehydrogenase transcription correlates in high-grade tumors. Cancer Res 2007; 67: 7917-22.
    • (2007) Cancer Res , vol.67 , pp. 7917-7922
    • Krugluger, W.1    Brandstaetter, A.2    Kallay, E.3
  • 28
    • 0022398782 scopus 로고
    • Pyrimidine base degradation in cultured murine C-1300 neuroblastoma cells and in situ tumors
    • Tuchman M, O'Dea RF, Ramnaraine ML, Mirkin BL. Pyrimidine base degradation in cultured murine C-1300 neuroblastoma cells and in situ tumors. Cancer Res 1985; 45: 5553-6.
    • (1985) Cancer Res , vol.45 , pp. 5553-5556
    • Tuchman, M.1    O'Dea, R.F.2    Ramnaraine, M.L.3    Mirkin, B.L.4
  • 29
    • 0024409993 scopus 로고
    • Correlations of dihydropyrimidine dehydrogenase, thymidine phosphorylase and thymidine kinase activities in strongly and weakly malignant cultured murine neuroblastoma cells
    • Williams CS, Tuchman M. Correlations of dihydropyrimidine dehydrogenase, thymidine phosphorylase and thymidine kinase activities in strongly and weakly malignant cultured murine neuroblastoma cells. Int J Cancer 1989; 43: 901-4.
    • (1989) Int J Cancer , vol.43 , pp. 901-904
    • Williams, C.S.1    Tuchman, M.2
  • 30
    • 0035004799 scopus 로고    scopus 로고
    • Circadian expression of clock genes in human oral mucosa and skin
    • Bjarnason GA, Jordan RC, Wood PA et al. Circadian expression of clock genes in human oral mucosa and skin. Am J Pathol 2001; 158: 1793-801.
    • (2001) Am J Pathol , vol.158 , pp. 1793-1801
    • Bjarnason, G.A.1    Jordan, R.C.2    Wood, P.A.3
  • 31
    • 1842453897 scopus 로고    scopus 로고
    • Circadian rhythm of dihydrouracil/uracil ratios in biological fluids: A potential biomarker for dihydropyrimidine dehydrogenase levels
    • Jiang H, Lu J, Ji J. Circadian rhythm of dihydrouracil/uracil ratios in biological fluids: A potential biomarker for dihydropyrimidine dehydrogenase levels. Br J Pharmacol 2004; 141: 616-23.
    • (2004) Br J Pharmacol , vol.141 , pp. 616-623
    • Jiang, H.1    Lu, J.2    Ji, J.3
  • 32
    • 0037375992 scopus 로고    scopus 로고
    • Dihydropyrimidine dehydrogenase circadian rhythm in mouse liver: Comparison between enzyme activity and gene expression
    • Porsin B, Formento JL, Filipski E et al. Dihydropyrimidine dehydrogenase circadian rhythm in mouse liver: Comparison between enzyme activity and gene expression. Eur J Cancer 2003; 39: 822-8.
    • (2003) Eur J Cancer , vol.39 , pp. 822-828
    • Porsin, B.1    Formento, J.L.2    Filipski, E.3
  • 34
    • 8644261000 scopus 로고    scopus 로고
    • Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in relation to differentiation of gastric cancer
    • Ichikawa W, Takahashi T, Suto K et al. Thymidylate synthase and dihydropyrimidine dehydrogenase gene expression in relation to differentiation of gastric cancer. Int J Cancer 2004; 112: 967-73.
    • (2004) Int J Cancer , vol.112 , pp. 967-973
    • Ichikawa, W.1    Takahashi, T.2    Suto, K.3
  • 35
    • 0015062926 scopus 로고
    • Behavior of opposing pathways of thymidine utilization in differentiating, regenerating, and neoplastic liver
    • Ferninandus JA, Moris HP, Weber G. Behavior of opposing pathways of thymidine utilization in differentiating, regenerating, and neoplastic liver. Cancer Res 1971; 31: 550-6.
    • (1971) Cancer Res , vol.31 , pp. 550-556
    • Ferninandus, J.A.1    Moris, H.P.2    Weber, G.3
  • 36
    • 1842480044 scopus 로고    scopus 로고
    • Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors
    • Lazarevich NL, Cheremnova OA, Varga EV et al. Progression of HCC in mice is associated with a downregulation in the expression of hepatocyte nuclear factors. Hepatology 2004; 39: 1038-47.
    • (2004) Hepatology , vol.39 , pp. 1038-1047
    • Lazarevich, N.L.1    Cheremnova, O.A.2    Varga, E.V.3
  • 37
    • 31544442216 scopus 로고    scopus 로고
    • Hepatoma-derived growth factor is a novel prognostic factor for hepatocellular carcinoma
    • Yoshida K, Tomita Y, Okuda Y et al. Hepatoma-derived growth factor is a novel prognostic factor for hepatocellular carcinoma. Ann Surg Oncol 2006; 13: 159-67.
    • (2006) Ann Surg Oncol , vol.13 , pp. 159-167
    • Yoshida, K.1    Tomita, Y.2    Okuda, Y.3
  • 38
    • 15444349773 scopus 로고    scopus 로고
    • p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site
    • Lenz HJ, Danenberg KD, Leichman CG et al. p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site. Clin Cancer Res 1998; 4: 1227-34.
    • (1998) Clin Cancer Res , vol.4 , pp. 1227-1234
    • Lenz, H.J.1    Danenberg, K.D.2    Leichman, C.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.