메뉴 건너뛰기




Volumn 39, Issue 3, 2009, Pages 282-289

Hepatitis C virus F protein inhibits cell apoptosis by activation of intracellular NF-κB pathway

Author keywords

Apoptosis; F protein; Hepatitis C virus; Nuclear factor kappa B

Indexed keywords

COMPLEMENTARY DNA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LUCIFERASE; PROTEIN F; SYNAPTOTAGMIN I; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

EID: 69249232358     PISSN: 13866346     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1872-034X.2008.00452.x     Document Type: Article
Times cited : (15)

References (32)
  • 1
    • 7444256169 scopus 로고    scopus 로고
    • Genetic diversity and evolution of hepatitis C virus -15years on
    • Simmonds P. Genetic diversity and evolution of hepatitis C virus -15years on. J Gen Virol 2004; 85: 3173-88.
    • (2004) J Gen Virol , vol.85 , pp. 3173-3188
    • Simmonds, P.1
  • 2
    • 0035955558 scopus 로고    scopus 로고
    • Recent advances in the molecular biology of hepatitis C virus
    • Rosenberg S. Recent advances in the molecular biology of hepatitis C virus. J Mol Biol 2001; 313: 451-64.
    • (2001) J Mol Biol , vol.313 , pp. 451-464
    • Rosenberg, S.1
  • 3
    • 0034053296 scopus 로고    scopus 로고
    • Properties of the hepatitis C virus core protein: A structural protein that modulates cellular processes
    • McLauchlan J. Properties of the hepatitis C virus core protein: A structural protein that modulates cellular processes. J Viral Hepat 2000; 7: 2-14.
    • (2000) J Viral Hepat , vol.7 , pp. 2-14
    • McLauchlan, J.1
  • 4
    • 0034602420 scopus 로고    scopus 로고
    • Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability
    • Otsuka M, Kato N, Lan K et al. Hepatitis C virus core protein enhances p53 function through augmentation of DNA binding affinity and transcriptional ability. J Biol Chem 2000; 275: 34122-30.
    • (2000) J Biol Chem , vol.275 , pp. 34122-34130
    • Otsuka, M.1    Kato, N.2    Lan, K.3
  • 5
    • 17544383005 scopus 로고    scopus 로고
    • Activation of nuclear factor kappa B in hepatitis C virus infection: Implications for pathogenesis and hepatocarcinogenesis
    • Tai DI, Tsai SL, Chen YM et al. Activation of nuclear factor kappa B in hepatitis C virus infection: Implications for pathogenesis and hepatocarcinogenesis. Hepatology 2000; 31: 656-64.
    • (2000) Hepatology , vol.31 , pp. 656-664
    • Tai, D.I.1    Tsai, S.L.2    Chen, Y.M.3
  • 6
    • 0036683052 scopus 로고    scopus 로고
    • Intra-membrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets
    • McLauchlan J, Lemberg MK, Hope G, Martoglio B. Intra-membrane proteolysis promotes trafficking of hepatitis C virus core protein to lipid droplets. EMBO J 2002; 21: 3980-88.
    • (2002) EMBO J , vol.21 , pp. 3980-3988
    • McLauchlan, J.1    Lemberg, M.K.2    Hope, G.3    Martoglio, B.4
  • 7
    • 0035898608 scopus 로고    scopus 로고
    • Synthesis of a novel hepatitis C virus protein by ribosomal frameshift
    • Xu Z, Choi J, Yen TS et al. Synthesis of a novel hepatitis C virus protein by ribosomal frameshift. EMBO J 2001; 20: 3840-8.
    • (2001) EMBO J , vol.20 , pp. 3840-3848
    • Xu, Z.1    Choi, J.2    Yen, T.S.3
  • 8
    • 0038158179 scopus 로고    scopus 로고
    • Characterization of the expression of the hepatitis C virus F protein
    • Roussel J, Pillez A, Montpellier C et al. Characterization of the expression of the hepatitis C virus F protein. J Gen Virol 2003; 84: 1751-9.
    • (2003) J Gen Virol , vol.84 , pp. 1751-1759
    • Roussel, J.1    Pillez, A.2    Montpellier, C.3
  • 9
    • 14644415892 scopus 로고    scopus 로고
    • The hepatitis C virus alternate reading frame (ARF) and its family of novel products: The alternate reading frame protein/F-protein, the double-frameshift protein, and others
    • Branch AD, Stump DD, Gutierrez JA, Eng F, Walewski JL. The hepatitis C virus alternate reading frame (ARF) and its family of novel products: the alternate reading frame protein/F-protein, the double-frameshift protein, and others. Semin Liver Dis 2005; 25: 105-17.
    • (2005) Semin Liver Dis , vol.25 , pp. 105-117
    • Branch, A.D.1    Stump, D.D.2    Gutierrez, J.A.3    Eng, F.4    Walewski, J.L.5
  • 10
    • 0035837040 scopus 로고    scopus 로고
    • Hepatitis C virus core protein enhances FADD-mediated apoptosis and suppresses TRADD signaling of tumor necrosis factor receptor
    • Zhu N, Ware CF, Lai MM. Hepatitis C virus core protein enhances FADD-mediated apoptosis and suppresses TRADD signaling of tumor necrosis factor receptor. Virology 2001; 283: 178-87.
    • (2001) Virology , vol.283 , pp. 178-187
    • Zhu, N.1    Ware, C.F.2    Lai, M.M.3
  • 11
    • 0033061215 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor a-mediated apoptosis via NF-?B activation
    • Marusawa H, Hijikata M, Chiba T, Shimotohno K. Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor a-mediated apoptosis via NF-?B activation. J Virol 1999; 73: 4713-20.
    • (1999) J Virol , vol.73 , pp. 4713-4720
    • Marusawa, H.1    Hijikata, M.2    Chiba, T.3    Shimotohno, K.4
  • 12
    • 35548997491 scopus 로고    scopus 로고
    • Hepatitis C virus F protein up-regulates c-myc and down-regulates p53 in human hepatoma HepG2 cells
    • Wu WB, Shao SW, Zhao LJ et al. Hepatitis C virus F protein up-regulates c-myc and down-regulates p53 in human hepatoma HepG2 cells. Intervirology 2007; 50: 341-6.
    • (2007) Intervirology , vol.50 , pp. 341-346
    • Wu, W.B.1    Shao, S.W.2    Zhao, L.J.3
  • 14
    • 33646166625 scopus 로고    scopus 로고
    • Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein
    • Saito K, Meyer K, Warner R, Basu A, Ray RB, Ray R. Hepatitis C virus core protein inhibits tumor necrosis factor alpha-mediated apoptosis by a protective effect involving cellular FLICE inhibitory protein. J Virol 2006; 80: 4372-79.
    • (2006) J Virol , vol.80 , pp. 4372-4379
    • Saito, K.1    Meyer, K.2    Warner, R.3    Basu, A.4    Ray, R.B.5    Ray, R.6
  • 15
    • 33845341103 scopus 로고    scopus 로고
    • Interaction of HCV core protein with 14-3-3epsilon protein releases Bax to activate apoptosis
    • Lee SK, Park SO, Joe CO, Kim YS. Interaction of HCV core protein with 14-3-3epsilon protein releases Bax to activate apoptosis. Biochem Biophys Res Commun 2007; 352: 756-62.
    • (2007) Biochem Biophys Res Commun , vol.352 , pp. 756-762
    • Lee, S.K.1    Park, S.O.2    Joe, C.O.3    Kim, Y.S.4
  • 16
    • 29144519760 scopus 로고    scopus 로고
    • E2 of hepatitis C virus inhibits apoptosis
    • Lee SH, Kim YK, Kim CS et al. E2 of hepatitis C virus inhibits apoptosis. J Immunol 2005; 175: 8226-35.
    • (2005) J Immunol , vol.175 , pp. 8226-8235
    • Lee, S.H.1    Kim, Y.K.2    Kim, C.S.3
  • 17
    • 33646394110 scopus 로고    scopus 로고
    • HCV E2 may induce apoptosis of Huh-7 cells via a mitochondrial-related caspase pathway
    • Chiou HL, Hsieh YS, Hsieh MR, Chen TY. HCV E2 may induce apoptosis of Huh-7 cells via a mitochondrial-related caspase pathway. Biochem Biophys Res Commun 2006; 345: 453-8.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 453-458
    • Chiou, H.L.1    Hsieh, Y.S.2    Hsieh, M.R.3    Chen, T.Y.4
  • 18
    • 5144227738 scopus 로고    scopus 로고
    • The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities
    • Prikhodko EA, Prikhodko GG, Siegel RM, Thompson P, Major ME, Cohen JI. The NS3 protein of hepatitis C virus induces caspase-8-mediated apoptosis independent of its protease or helicase activities. Virology 2004; 329: 53-67.
    • (2004) Virology , vol.329 , pp. 53-67
    • Prikhodko, E.A.1    Prikhodko, G.G.2    Siegel, R.M.3    Thompson, P.4    Major, M.E.5    Cohen, J.I.6
  • 19
    • 33745624260 scopus 로고    scopus 로고
    • Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosis
    • Nomura-Takigawa Y, Nagano-Fujii M, Deng L et al. Non-structural protein 4A of Hepatitis C virus accumulates on mitochondria and renders the cells prone to undergoing mitochondria-mediated apoptosis. J Gen Virol 2006; 87: 1935-45.
    • (2006) J Gen Virol , vol.87 , pp. 1935-1945
    • Nomura-Takigawa, Y.1    Nagano-Fujii, M.2    Deng, L.3
  • 20
    • 0037130462 scopus 로고    scopus 로고
    • HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis
    • Lan KH, Sheu ML, Hwang SJ et al. HCV NS5A interacts with p53 and inhibits p53-mediated apoptosis. Oncogene 2002; 21: 4801-11.
    • (2002) Oncogene , vol.21 , pp. 4801-4811
    • Lan, K.H.1    Sheu, M.L.2    Hwang, S.J.3
  • 21
    • 0035859871 scopus 로고    scopus 로고
    • Human hepatitis C virus. NS5A protein alters intracellular calcium levels, induces Oxidative stress, and activates STAT-3 and NF-kappa B
    • Gong G, Waris G, Tanveer R, Siddiqui A. Human hepatitis C virus. NS5A protein alters intracellular calcium levels, induces oxidative stress, and activates STAT-3 and NF-kappa B. Proc Natl Acad Sci USA 2001; 98: 9599-604.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 9599-9604
    • Gong, G.1    Waris, G.2    Tanveer, R.3    Siddiqui, A.4
  • 22
    • 12944293008 scopus 로고    scopus 로고
    • Hepatitis C virus core, NS3, NS5A, NS5B proteins induce apoptosis in mature dendritic cells
    • Siavoshian S, Abraham JD, Thumann C, Kieny MP, Schuster C. Hepatitis C virus core, NS3, NS5A, NS5B proteins induce apoptosis in mature dendritic cells. J Med Virol 2005; 75: 402-11.
    • (2005) J Med Virol , vol.75 , pp. 402-411
    • Siavoshian, S.1    Abraham, J.D.2    Thumann, C.3    Kieny, M.P.4    Schuster, C.5
  • 23
    • 0038393124 scopus 로고    scopus 로고
    • The death effector domain protein family: Regulators of cellular homeostasis
    • Tibbetts MD, Zheng L, Lenardo MJ. The death effector domain protein family: Regulators of cellular homeostasis. Nat Immunol 2003; 4: 404-9.
    • (2003) Nat Immunol , vol.4 , pp. 404-409
    • Tibbetts, M.D.1    Zheng, L.2    Lenardo, M.J.3
  • 24
    • 14544269951 scopus 로고    scopus 로고
    • NF-kappaB in human disease: Current inhibitors and prospects for de novo structure based design of inhibitors
    • Pande V, Ramos MJ. NF-kappaB in human disease: Current inhibitors and prospects for de novo structure based design of inhibitors. Curr Med Chem 2005; 12: 357-74.
    • (2005) Curr Med Chem , vol.12 , pp. 357-374
    • Pande, V.1    Ramos, M.J.2
  • 25
    • 0037059745 scopus 로고    scopus 로고
    • RelB cellular regulation and transcriptional activity are regulated by p100
    • Solan NJ, Miyoshi H, Carmona EM, Bren GD, Paya CV. RelB cellular regulation and transcriptional activity are regulated by p100. J Biol Chem 2002; 277: 1405-18.
    • (2002) J Biol Chem , vol.277 , pp. 1405-1418
    • Solan, N.J.1    Miyoshi, H.2    Carmona, E.M.3    Bren, G.D.4    Paya, C.V.5
  • 26
    • 11844269840 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappaB and IkappaB proteins: Implications in cancer and inflammation
    • Viatour P, Merville MP, Bours V, Chariot A. Phosphorylation of NF-kappaB and IkappaB proteins: Implications in cancer and inflammation. Trends Biochem Sci 2005; 30: 43-52.
    • (2005) Trends Biochem Sci , vol.30 , pp. 43-52
    • Viatour, P.1    Merville, M.P.2    Bours, V.3    Chariot, A.4
  • 27
    • 33845700383 scopus 로고    scopus 로고
    • Induction of high molecular weight (HMW) tumor necrosis factor (TNF) alpha by hepatitis C virus (HCV) non-structural protein 3 (NS3) in liver cells is AP-1 and NF-kappaB-dependent activation
    • Hassan M, Selimovic D, Ghozlan H, Abdel-Kader O. Induction of high molecular weight (HMW) tumor necrosis factor (TNF) alpha by hepatitis C virus (HCV) non-structural protein 3 (NS3) in liver cells is AP-1 and NF-kappaB-dependent activation. Cell Signal 2007; 19: 301-11.
    • (2007) Cell Signal , vol.19 , pp. 301-311
    • Hassan, M.1    Selimovic, D.2    Ghozlan, H.3    Abdel-Kader, O.4
  • 28
    • 33748880164 scopus 로고    scopus 로고
    • Up-regulation of ERK and p38 MAPK signaling pathways by hepatitis C virus E2 envelope protein in human T lymphoma cell line
    • Zhao LJ, Zhang XL, Zhao P et al. Up-regulation of ERK and p38 MAPK signaling pathways by hepatitis C virus E2 envelope protein in human T lymphoma cell line. J Leukoc Biol 2006; 80: 424-32.
    • (2006) J Leukoc Biol , vol.80 , pp. 424-432
    • Zhao, L.J.1    Zhang, X.L.2    Zhao, P.3
  • 29
    • 0042733392 scopus 로고    scopus 로고
    • Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2
    • Park KJ, Choi SH, Choi DH et al. Hepatitis C virus NS5A protein modulates c-Jun N-terminal kinase through interaction with tumor necrosis factor receptor-associated factor 2. J Biol Chem 2003; 278: 30711-18.
    • (2003) J Biol Chem , vol.278 , pp. 30711-30718
    • Park, K.J.1    Choi, S.H.2    Choi, D.H.3
  • 30
    • 33645803192 scopus 로고    scopus 로고
    • Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase
    • Choi SH, Park KJ, Ahn BY, Jung G, Lai MM, Hwang SB. Hepatitis C virus nonstructural 5B protein regulates tumor necrosis factor alpha signaling through effects on cellular IkappaB kinase. Mol Cell Biol 2006; 26: 3048-59.
    • (2006) Mol Cell Biol , vol.26 , pp. 3048-3059
    • Choi, S.H.1    Park, K.J.2    Ahn, B.Y.3    Jung, G.4    Lai, M.M.5    Hwang, S.B.6
  • 31
    • 33748976352 scopus 로고    scopus 로고
    • Hepatitis C virus core protein induces expression of genes regulating immune evasion and anti-apoptosis in hepatocytes
    • Nguyen H, Sankaran S, Dandekar S. Hepatitis C virus core protein induces expression of genes regulating immune evasion and anti-apoptosis in hepatocytes. Virology 2006; 354: 58-68.
    • (2006) Virology , vol.354 , pp. 58-68
    • Nguyen, H.1    Sankaran, S.2    Dandekar, S.3
  • 32
    • 19944411839 scopus 로고    scopus 로고
    • Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta
    • Joo M, Hahn YS, Kwon M, Sadikot RT, Blackwell TS, Christman JW. Hepatitis C virus core protein suppresses NF-kappaB activation and cyclooxygenase-2 expression by direct interaction with IkappaB kinase beta. J Virol 2005; 79: 7648-57.
    • (2005) J Virol , vol.79 , pp. 7648-7657
    • Joo, M.1    Hahn, Y.S.2    Kwon, M.3    Sadikot, R.T.4    Blackwell, T.S.5    Christman, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.