Antibody aggregate removal by hydroxyapatite chromatography

Current Pharmaceutical Biotechnology

Volumn 10, Issue 4, 2009, Pages 440-446

  Gagnon, Pete ^a   Beam, Kevin ^b  

^a Validated Biosystems   (United States)

^b SEATTLE GENETICS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; MONOCLONAL ANTIBODY; ANTIBODY; HYDROXYAPATITE; MULTIPROTEIN COMPLEX;

ANION EXCHANGE; BINDING AFFINITY; CATION EXCHANGE; CHROMATOGRAPHY; ELUTION; HYDROXYAPATITE CHROMATOGRAPHY; IMMUNOGLOBULIN AGGREGATE; MOLECULAR WEIGHT; NONHUMAN; PROCESS DEVELOPMENT; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN PURIFICATION; REPRODUCIBILITY; REVIEW; SCALE UP; THERMODYNAMICS; CHEMISTRY; FRACTIONATION; ISOLATION AND PURIFICATION; METHODOLOGY; PHARMACEUTICS;

ANTIBODIES; BIOPHARMACEUTICS; CHEMICAL FRACTIONATION; CHROMATOGRAPHY; HYDROXYAPATITES; MULTIPROTEIN COMPLEXES; TECHNOLOGY, PHARMACEUTICAL;

EID: 69249221640     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920109788488833     Document Type: Review

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