Use of an alternative scale-down approach to predict and extend hydroxyapatite column lifetimes

Journal of Chromatography A

Volumn 1165, Issue 1-2, 2007, Pages 78-85

  McCue, Justin T ^a   Cecchini, Douglas ^a   Hawkins, Kenneth ^a   Dolinski, Eric ^a  

^a BIOGEN   (United States)

Author keywords

Column lifetime; Hydroxyapatite; Preparative chromatography; Scale up

Indexed keywords

CALCIUM PHOSPHATE; CHROMATOGRAPHY; PH EFFECTS; PROTEINS; PURIFICATION;

CERAMIC HYDROXYAPATITE (CHT); MOBILE PHASE FORMULATIONS; MOBILE PHASE SCREENING; PREPARATIVE CHROMATOGRAPHY;

HYDROXYAPATITE;

HYDROXYAPATITE; RECOMBINANT PROTEIN;

ARTICLE; CERAMICS; COLUMN CHROMATOGRAPHY; METHODOLOGY; PRIORITY JOURNAL; PROTEIN PURIFICATION;

CERAMICS; CHROMATOGRAPHY; DURAPATITE; PROTEINS;

EID: 34548180271     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2007.07.053     Document Type: Article

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