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Volumn 2009, Issue , 2009, Pages

Inhibitory effect of flavonoids on the efflux of N -acetyl 5-aminosalicylic acid intracellularly formed in caco-2 cells

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXYFLAVONE; 3',4' DIHYDROXYFLAVONE; 5 ACETAMIDOSALICYLIC ACID; 7 HYDROXYFLAVONE; 7,3',4' TRIHYDROXYFLAVONE; 7,4' DIHYDROXYFLAVONE; APIGENIN; CHRYSIN; CYCLOSPORIN A; DIOSMETIN; EPICATECHIN; EPIGALLOCATECHIN; FISETIN; FLAVONOID; GALANGIN; GERALDOL; GESTONORONE CAPROATE; GLYCOPROTEIN P INHIBITOR; INDOMETACIN; ISORHAMNETIN; KAEMPFEROL; LUTEOLIN; MESALAZINE; MITOXANTRONE; MORIN; PRIMULETIN; QUERCETIN; QUINIDINE; TAXIFOLIN; UNCLASSIFIED DRUG; VERLUKAST;

EID: 69249215244     PISSN: 11107243     EISSN: 11107251     Source Type: Journal    
DOI: 10.1155/2009/467489     Document Type: Article
Times cited : (8)

References (39)
  • 1
    • 0015916139 scopus 로고
    • Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype
    • Das K. M., Eastwood M. A., McManus J. P., Sircus W., Adverse reactions during salicylazosulfapyridine therapy and the relation with drug metabolism and acetylator phenotype The New England Journal of Medicine 1973 289 10 491 495
    • (1973) The New England Journal of Medicine , vol.289 , Issue.10 , pp. 491-495
    • Das, K.M.1    Eastwood, M.A.2    McManus, J.P.3    Sircus, W.4
  • 2
    • 0036337583 scopus 로고    scopus 로고
    • Comparative tolerability of therapies for ulcerative colitis
    • Ardizzone S., Porro G. B., Comparative tolerability of therapies for ulcerative colitis Drug Safety 2002 25 8 561 582
    • (2002) Drug Safety , vol.25 , Issue.8 , pp. 561-582
    • Ardizzone, S.1    Porro, G.B.2
  • 3
    • 0024362207 scopus 로고
    • Colonic N -acetylation of 5-aminosalicylic acid in inflammatory bowel disease
    • Allgayer H., Ahnfelt N. O., Kruis W., Colonic N -acetylation of 5-aminosalicylic acid in inflammatory bowel disease Gastroenterology 1989 97 1 38 41
    • (1989) Gastroenterology , vol.97 , Issue.1 , pp. 38-41
    • Allgayer, H.1    Ahnfelt, N.O.2    Kruis, W.3
  • 4
    • 0036310989 scopus 로고    scopus 로고
    • N -acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis
    • Ricart E., Taylor W. R., Loftus E. V., N -acetyltransferase 1 and 2 genotypes do not predict response or toxicity to treatment with mesalamine and sulfasalazine in patients with ulcerative colitis American Journal of Gastroenterology 2002 97 7 1763 1768
    • (2002) American Journal of Gastroenterology , vol.97 , Issue.7 , pp. 1763-1768
    • Ricart, E.1    Taylor, W.R.2    Loftus, E.V.3
  • 5
    • 20544443990 scopus 로고    scopus 로고
    • Evaluation of biotransformation of sulphasalazine in the colon epithelial Caco-2 cells
    • Bat B., Lodowska J., Orchel A., Evaluation of biotransformation of sulphasalazine in the colon epithelial Caco-2 cells Acta Poloniae Pharmaceutica 2004 61 8 10
    • (2004) Acta Poloniae Pharmaceutica , vol.61 , pp. 8-10
    • Bat, B.1    Lodowska, J.2    Orchel, A.3
  • 6
    • 0018084814 scopus 로고
    • Role of prostaglandins in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine
    • Sharon P., Ligumsky M., Rachmilewitz D., Zor U., Role of prostaglandins in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine Gastroenterology 1978 75 4 638 640
    • (1978) Gastroenterology , vol.75 , Issue.4 , pp. 638-640
    • Sharon, P.1    Ligumsky, M.2    Rachmilewitz, D.3    Zor, U.4
  • 7
    • 0020657940 scopus 로고
    • Inhibition of prostaglandin synthetase in human rectal mucosa
    • Hawkey C. J., Truelove S. C., Inhibition of prostaglandin synthetase in human rectal mucosa Gut 1983 24 3 213 217
    • (1983) Gut , vol.24 , Issue.3 , pp. 213-217
    • Hawkey, C.J.1    Truelove, S.C.2
  • 9
    • 0028934947 scopus 로고
    • Delivery and fate of oral mesalamine microgranules within the human small intestine
    • Layer P. H., Goebell H., Keller J., Dignass A., Klotz U., Delivery and fate of oral mesalamine microgranules within the human small intestine Gastroenterology 1995 108 5 1427 1433
    • (1995) Gastroenterology , vol.108 , Issue.5 , pp. 1427-1433
    • Layer, P.H.1    Goebell, H.2    Keller, J.3    Dignass, A.4    Klotz, U.5
  • 10
    • 0031308467 scopus 로고    scopus 로고
    • Intestinal fate of 5-aminosalicylic acid: Regional and systemic kinetic studies in relation to inflammatory bowel disease
    • supplement 2
    • Bondesen S., Intestinal fate of 5-aminosalicylic acid: regional and systemic kinetic studies in relation to inflammatory bowel disease Pharmacology and Toxicology 1997 81 supplement 2 1 28
    • (1997) Pharmacology and Toxicology , vol.81 , pp. 1-28
    • Bondesen, S.1
  • 12
    • 18244376403 scopus 로고    scopus 로고
    • Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters
    • Di Pietro A., Conseil G., Prez-Victoria J. M., Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters Cellular and Molecular Life Sciences 2002 59 2 307 322
    • (2002) Cellular and Molecular Life Sciences , vol.59 , Issue.2 , pp. 307-322
    • Di Pietro, A.1    Conseil, G.2    Prez-Victoria, J.M.3
  • 13
    • 0037371275 scopus 로고    scopus 로고
    • Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport
    • Zhang S., Morris M. E., Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport Journal of Pharmacology and Experimental Therapeutics 2003 304 3 1258 1267
    • (2003) Journal of Pharmacology and Experimental Therapeutics , vol.304 , Issue.3 , pp. 1258-1267
    • Zhang, S.1    Morris, M.E.2
  • 14
    • 28444484982 scopus 로고    scopus 로고
    • Expression and function of efflux drug transporters in the intestine
    • Takano M., Yumoto R., Murakami T., Expression and function of efflux drug transporters in the intestine Pharmacology and Therapeutics 2006 109 1-2 137 161
    • (2006) Pharmacology and Therapeutics , vol.109 , Issue.12 , pp. 137-161
    • Takano, M.1    Yumoto, R.2    Murakami, T.3
  • 15
    • 0035033774 scopus 로고    scopus 로고
    • Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATpase activities by interaction with dietary flavonoids
    • Leslie E. M., Mao Q., Oleschuk C. J., Deeley R. G., Cole S. P. C., Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATpase activities by interaction with dietary flavonoids Molecular Pharmacology 2001 59 5 1171 1180
    • (2001) Molecular Pharmacology , vol.59 , Issue.5 , pp. 1171-1180
    • Leslie, E.M.1    Mao, Q.2    Oleschuk, C.J.3    Deeley, R.G.4    Cole, S.P.C.5
  • 16
    • 0842348982 scopus 로고    scopus 로고
    • Flavonoids as inhibitors of MRP1-like efflux activity in human erythrocytes. A structure-activity relationship study
    • Bobrowska-Hgerstrand M., Wrbel A., Mrwczyska L., Flavonoids as inhibitors of MRP1-like efflux activity in human erythrocytes. A structure-activity relationship study Oncology Research 2003 13 11 463 469
    • (2003) Oncology Research , vol.13 , Issue.11 , pp. 463-469
    • Bobrowska-Hgerstrand, M.1    Wrbel, A.2    Mrwczyska, L.3
  • 17
    • 9944228236 scopus 로고    scopus 로고
    • Metabolic O-demethylation does not alter the influence of isoflavones on the biophysical properties of membranes and MRP1-like protein transport activity
    • ania-Pietrzak B., Hendrich A. B., Zugaj J., Michalak K., Metabolic O-demethylation does not alter the influence of isoflavones on the biophysical properties of membranes and MRP1-like protein transport activity Archives of Biochemistry and Biophysics 2005 433 2 428 434
    • (2005) Archives of Biochemistry and Biophysics , vol.433 , Issue.2 , pp. 428-434
    • Ania-Pietrzak, B.1    Hendrich, A.B.2    Zugaj, J.3    Michalak, K.4
  • 18
    • 12744256734 scopus 로고    scopus 로고
    • Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2
    • Van Zanden J. J., Wortelboer H. M., Bijlsma S., Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2 Biochemical Pharmacology 2005 69 4 699 708
    • (2005) Biochemical Pharmacology , vol.69 , Issue.4 , pp. 699-708
    • Van Zanden, J.J.1    Wortelboer, H.M.2    Bijlsma, S.3
  • 19
    • 19344377052 scopus 로고    scopus 로고
    • Reversal of in vitro cellular MRP1 and MRP2 mediated vincristine resistance by the flavonoid myricetin
    • Van Zanden J. J., De Mul A., Wortelboer H. M., Reversal of in vitro cellular MRP1 and MRP2 mediated vincristine resistance by the flavonoid myricetin Biochemical Pharmacology 2005 69 11 1657 1665
    • (2005) Biochemical Pharmacology , vol.69 , Issue.11 , pp. 1657-1665
    • Van Zanden, J.J.1    De Mul, A.2    Wortelboer, H.M.3
  • 20
    • 34250004857 scopus 로고    scopus 로고
    • The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential
    • Van Zanden J. J., van der Woude H., Vaessen J., The effect of quercetin phase II metabolism on its MRP1 and MRP2 inhibiting potential Biochemical Pharmacology 2007 74 2 345 351
    • (2007) Biochemical Pharmacology , vol.74 , Issue.2 , pp. 345-351
    • Van Zanden, J.J.1    Van Der Woude, H.2    Vaessen, J.3
  • 21
    • 0023160413 scopus 로고
    • Simultaneous determination of 5-aminosalicylic acid and 5-acetylaminosalicylic acid by high-performance liquid chromatography
    • Brendel E., Meineke I., Witsch D., Zschunke M., Simultaneous determination of 5-aminosalicylic acid and 5-acetylaminosalicylic acid by high-performance liquid chromatography Journal of Chromatography 1987 385 299 304
    • (1987) Journal of Chromatography , vol.385 , pp. 299-304
    • Brendel, E.1    Meineke, I.2    Witsch, D.3    Zschunke, M.4
  • 22
    • 33646596954 scopus 로고    scopus 로고
    • Effect of benzo[a]pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer
    • Sugihara N., Toyama K., Michihara A., Akasaki K., Tsuji H., Furuno K., Effect of benzo[a]pyrene on P-glycoprotein-mediated transport in Caco-2 cell monolayer Toxicology 2006 223 1-2 156 165
    • (2006) Toxicology , vol.223 , Issue.12 , pp. 156-165
    • Sugihara, N.1    Toyama, K.2    Michihara, A.3    Akasaki, K.4    Tsuji, H.5    Furuno, K.6
  • 23
    • 16644375860 scopus 로고    scopus 로고
    • Inhibitory effect of flavonoids on N -acetylation of 5-aminosalicylic acid in cultured rat hepatocytes
    • Mizoyama Y., Takaki H., Sugihara N., Furuno K., Inhibitory effect of flavonoids on N -acetylation of 5-aminosalicylic acid in cultured rat hepatocytes Biological and Pharmaceutical Bulletin 2004 27 9 1455 1458
    • (2004) Biological and Pharmaceutical Bulletin , vol.27 , Issue.9 , pp. 1455-1458
    • Mizoyama, Y.1    Takaki, H.2    Sugihara, N.3    Furuno, K.4
  • 24
    • 0033847137 scopus 로고    scopus 로고
    • Efflux of dietary flavonoid quercetin 4 ′ - ---glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance- associated protein-21
    • Walgren R. A., Karnaky K. J. Jr., Lindenmayer G. E., Walle T., Efflux of dietary flavonoid quercetin 4 ′- -glucoside across human intestinal Caco-2 cell monolayers by apical multidrug resistance-associated protein-21 Journal of Pharmacology and Experimental Therapeutics 2000 294 3 830 836
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.294 , Issue.3 , pp. 830-836
    • Walgren, R.A.1    Karnaky Jr., K.J.2    Lindenmayer, G.E.3    Walle, T.4
  • 25
    • 0141849078 scopus 로고    scopus 로고
    • Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites
    • Hong J., Lambert J. D., Lee S.-H., Sinko P. J., Yang C. S., Involvement of multidrug resistance-associated proteins in regulating cellular levels of (-)-epigallocatechin-3-gallate and its methyl metabolites Biochemical and Biophysical Research Communications 2003 310 1 222 227
    • (2003) Biochemical and Biophysical Research Communications , vol.310 , Issue.1 , pp. 222-227
    • Hong, J.1    Lambert, J.D.2    Lee, S.-H.3    Sinko, P.J.4    Yang, C.S.5
  • 26
    • 33645885302 scopus 로고    scopus 로고
    • Ochratoxin A secretion by ATP-dependent membrane transporters in Caco-2 cells
    • Schrickx J., Lektarau Y., Fink-Gremmels J., Ochratoxin A secretion by ATP-dependent membrane transporters in Caco-2 cells Archives of Toxicology 2006 80 5 243 249
    • (2006) Archives of Toxicology , vol.80 , Issue.5 , pp. 243-249
    • Schrickx, J.1    Lektarau, Y.2    Fink-Gremmels, J.3
  • 27
    • 10844279077 scopus 로고    scopus 로고
    • Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux
    • Honda Y., Ushigome F., Koyabu N., Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux British Journal of Pharmacology 2004 143 7 856 864
    • (2004) British Journal of Pharmacology , vol.143 , Issue.7 , pp. 856-864
    • Honda, Y.1    Ushigome, F.2    Koyabu, N.3
  • 28
    • 33745698221 scopus 로고    scopus 로고
    • Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea
    • Takasuna K., Hagiwara T., Watanabe K., Optimal antidiarrhea treatment for antitumor agent irinotecan hydrochloride (CPT-11)-induced delayed diarrhea Cancer Chemotherapy and Pharmacology 2006 58 4 494 503
    • (2006) Cancer Chemotherapy and Pharmacology , vol.58 , Issue.4 , pp. 494-503
    • Takasuna, K.1    Hagiwara, T.2    Watanabe, K.3
  • 29
    • 33644758036 scopus 로고    scopus 로고
    • Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development
    • Yanase K., Tsukahara S., Mitsuhashi J., Sugimoto Y., Functional SNPs of the breast cancer resistance protein-therapeutic effects and inhibitor development Cancer Letters 2006 234 1 73 80
    • (2006) Cancer Letters , vol.234 , Issue.1 , pp. 73-80
    • Yanase, K.1    Tsukahara, S.2    Mitsuhashi, J.3    Sugimoto, Y.4
  • 30
    • 0030063480 scopus 로고    scopus 로고
    • Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump
    • Jedlitschky G., Leier I., Buchholz U., Barnouin K., Kurz G., Keppler D., Transport of glutathione, glucuronate, and sulfate conjugates by the MRP gene-encoded conjugate export pump Cancer Research 1996 56 5 988 994 (Pubitemid 26065391)
    • (1996) Cancer Research , vol.56 , Issue.5 , pp. 988-994
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Barnouin, K.4    Kurz, G.5    Keppler, D.6
  • 31
    • 0344927562 scopus 로고    scopus 로고
    • Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
    • Konig J., Nies A. T., Cui Y., Leier I., Keppler D., Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance Biochimica et Biophysica Acta 1999 1461 2 377 394
    • (1999) Biochimica et Biophysica Acta , vol.1461 , Issue.2 , pp. 377-394
    • Konig, J.1    Nies, A.T.2    Cui, Y.3    Leier, I.4    Keppler, D.5
  • 32
    • 0037131880 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): Its impact on drug disposition
    • Suzuki H., Sugiyama Y., Single nucleotide polymorphisms in multidrug resistance associated protein 2 (MRP2/ABCC2): its impact on drug disposition Advanced Drug Delivery Reviews 2002 54 1319 1331
    • (2002) Advanced Drug Delivery Reviews , vol.54 , pp. 1319-1331
    • Suzuki, H.1    Sugiyama, Y.2
  • 33
    • 0033958156 scopus 로고    scopus 로고
    • Involvement of an organic anion transporter (canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2) in gastrointestinal secretion of glutathione conjugates in rats
    • Gotoh Y., Suzuki H., Kinoshita S., Hirohashi T., Kato Y., Sugiyama Y., Involvement of an organic anion transporter (canalicular multispecific organic anion transporter/multidrug resistance-associated protein 2) in gastrointestinal secretion of glutathione conjugates in rats Journal of Pharmacology and Experimental Therapeutics 2000 292 1 433 439
    • (2000) Journal of Pharmacology and Experimental Therapeutics , vol.292 , Issue.1 , pp. 433-439
    • Gotoh, Y.1    Suzuki, H.2    Kinoshita, S.3    Hirohashi, T.4    Kato, Y.5    Sugiyama, Y.6
  • 34
    • 0042858530 scopus 로고    scopus 로고
    • Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites
    • Slitt A. L., Cherrington N. J., Maher J. M., Klaassen C. D., Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites Drug Metabolism and Disposition 2003 31 9 1176 1186
    • (2003) Drug Metabolism and Disposition , vol.31 , Issue.9 , pp. 1176-1186
    • Slitt, A.L.1    Cherrington, N.J.2    Maher, J.M.3    Klaassen, C.D.4
  • 36
    • 0020626421 scopus 로고
    • Flavonoids, a class of natural products of high pharmacological potency
    • Havsteen B., Flavonoids, a class of natural products of high pharmacological potency Biochemical Pharmacology 1983 32 7 1141 1148
    • (1983) Biochemical Pharmacology , vol.32 , Issue.7 , pp. 1141-1148
    • Havsteen, B.1
  • 37
    • 0029867672 scopus 로고    scopus 로고
    • Flavonoidschemistry, metabolism, cardioprotective effects, and dietary sources
    • Cook N. C., Samman S., Flavonoidschemistry, metabolism, cardioprotective effects, and dietary sources Journal of Nutritional Biochemistry 1996 7 2 66 76
    • (1996) Journal of Nutritional Biochemistry , vol.7 , Issue.2 , pp. 66-76
    • Cook, N.C.1    Samman, S.2


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