Human vaginal Lactobacillus rhamnosus harbor mutation in 23S rRNA associated with erythromycin resistance

Research in Microbiology

Volumn 160, Issue 6, 2009, Pages 421-426

  Begovic, Jelena ^a   Huys, Geert ^b   Mayo, Baltasar ^c   D'Haene, Klaas ^b   Florez, Ana Belén ^c   Lozo, Jelena ^a   Kojic, Milan ^a   Strahinic, Ivana ^a   Topisirovic, Ljubisa ^a  

^a UNIVERSITY OF BELGRADE   (Serbia)

^b GHENT UNIVERSITY   (Belgium)

^c DEPARTMENT OF MICROBIOLOGY AND BIOCHEMISTRY OF DAIRY PRODUCTS   (Spain)

Author keywords

23S rRNA mutation; Erythromycin resistance; Lactobacillus rhamnosus; Vaginal lactobacilli

Indexed keywords

ERYTHROMYCIN; METHYLTRANSFERASE; PROTEIN ERMA; PROTEIN ERMB; PROTEIN ERMC; RNA 23S; UNCLASSIFIED DRUG;

AMPLICON; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL MUTATION; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; DILUTION; FEMALE; HETEROZYGOSITY; HUMAN; LACTOBACILLUS RHAMNOSUS; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR MECHANICS; NONHUMAN; OPERON; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RNA SEQUENCE; SCREENING; SEQUENCE ANALYSIS; VAGINA;

ANTI-BACTERIAL AGENTS; BASE SEQUENCE; DNA, BACTERIAL; DNA, RIBOSOMAL; DRUG RESISTANCE, BACTERIAL; ERYTHROMYCIN; FEMALE; HUMANS; LACTOBACILLUS RHAMNOSUS; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; MUTATION; RNA, RIBOSOMAL, 23S; VAGINA;

LACTOBACILLUS RHAMNOSUS;

EID: 69249213404     PISSN: 09232508     EISSN: 17697123     Source Type: Journal    
DOI: 10.1016/j.resmic.2009.07.005     Document Type: Article

References (33)

1. Asahara T., Takahashi M., Nomoto K., Takayama H., Onoue M., Morotomi M., Tanaka R., Yokokura T., et al. Assessment of safety of Lactobacillus strains based on resistance to host innate defense mechanisms. Clin. Diagn. Lab. Immunol. 10 (2003) 169-173
2. Austin D.J., Kakehashi M., and Anderson R.M. The transmission dynamics of antibiotic-resistant bacteria, the relationship between resistance in commensal organisms and antibiotic consumption. Proc. R. Soc. Lond. 264 (1997) 1629-1638
3. Beigi R., Austin M., Meyn L., Krohn M., and Hillier S. Antimicrobial resistance associated with the treatment of bacterial vaginosis. Am. J. Obstet. Gynecol. 191 (2004) 1124-1129
4. Bonhoeffer S., Lipstich M., and Levin B.R. Evaluating treatment protocols to prevent antibiotic resistance. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 12106-12111
5. Byin R., Nadkarni M.A., Chhour K.L., Martin F.E., Jacques N.A., and Hunter N. Quantitative analysis of diverse Lactobacillus species present in advanced dental caries. J. Clin. Microbiol. 42 (2004) 3128-3136
6. Cannon J.P., Lee T.A., Bolanos J.T., and Danziger L.H. Pathogenic relevance of Lactobacillus, a retrospective review of over 200 cases. Eur. J. Clin. Microbiol. Infect. Dis. 24 (2005) 31-40
7. Cataloluk O., and Gogebakan B. Presence of drug resistance in intestinal lactobacilli of dairy and human origin in Turkey. FEMS Microbiol. Lett. 236 (2004) 7-12
8. Danielsen M., and Wind D. Susceptibility of Lactobacillus spp. to antimicrobial agents. Int. J. Food Microbiol. 82 (2003) 1-11
9. Donoghue D.J. Antibiotic residues in poultry tissues and eggs, human health concerns?. Poult. Sci. 82 (2003) 618-621
10. Douthwaite S., and Aagaard C. Eythromycin binding is reduced in ribosomes with conformational alternations in the 23S rRNA peptidyl transferase loop. J. Mol. Biol. 3 (1993) 725-731
11. Farell D.J., Douthwaite S., Morrisey I., Bakker S., Poehlsgaard J., Jakobsen L., and Felmingham D. Macrolide resistance by ribosomal mutation in clinical isolates of Streptococcus pneumoniae from the PROTEKT 1999-2000 study. Antimicrob. Agents Chemother. 47 (2003) 1777-1783
12. Falagas M.E., Betsi G.I., and Athanasov S. Probiotics for prevention of recurrent vuvovaginal candidiasis, a review. J. Antimicrob. Chemother. 58 (2006) 266-272
13. Flórez A.B., Ladero V., Álvarez-Martín P., Ammor M.S., Alvarez M.A., and Mayo B. Acquired macrolide resistance in the human intestinal strain Lactobacillus rhamnosus E41 associated with a transition mutation in 23S rRNA genes. Int. J. Antimicrob. Agents 30 (2007) 341-344
14. Gasser F. Safety of lactic acid bacteria and their occurrence in human clinical infections. Bull. Inst. Pasteur 92 (1994) 45-67
15. Gevers D., Danielsen M., Huys G., and Swings J. Molecular characterization of tet(M) genes in Lactobacillus isolates from different types of fermented dry sausages. Appl. Environ. Microbiol. 69 (2003) 1270-1275
16. Hopwood D.A., Bibb M.J., Chater K.F., Kieser T., Bruton C.J., Kieser H.M., Lydate J.D., Smith C.P., et al. Genetic Manipulation of Streptomyces, A Laboratory Manual (1985), The John Innes Foundation, Norwich
17. Hunt D.E., Klepac-Ceraj V., Acinas S.G., Gautier C., Bertilsson S., and Polz M.F. Evaluation of 23S rRNA PCR primers for use in phylogenetic studies of bacterial diversity. Appl. Environ. Microbiol. 72 (2006) 2221-2225
18. Huys G., D'Haene K., and Swings J. Genetic basis of tetracycline and minocycline resistance in the potentially probiotic Lactobacillus plantarum strain CCUG 43738. Antimicrob. Agents Chemother. 50 (2006) 1550-1551
19. Huys G., D'Haene K., Danielsen M., Mättö J., Egervärn M., and Vandamme P. Phenotypic and molecular assessment of antimicrobial resistance in Lactobacillus paracasei strains from food origin. J. Food Prot. 71 (2008) 339-344
20. Jensen L.B., Frimodt-Moller N., and Aarestrup F.M. Presence of erm gene classes in gram-positive bacteria of animal and human origin in Denmark. FEMS Microbiol. Lett. 170 (1999) 151-158
21. Klare I., Konstabel C., Müller-Bertling S., Reissbrodt R., Huys G., Vancanneyt M., Swings J., Goossens H., and Witte W. Evaluation of new broth media for microdilution antibiotic susceptibility testing of lactobacilli, pediococci, lactococci, and bifidobacteria. Appl. Environ. Microbiol. 71 (2005) 8982-8986
22. Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E., Pavlov A., Pavlova N., et al. Comparative genomics of the lactic acid bacteria. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 15611-15616
23. Mastromarino P., Macchia S., Meggiorini L., Trichieri V., Mosca L., Perluigi M., and Midulla C. Effectiveness of Lactobacillus-containing vaginal tablets in the treatment of symptomatic bacterial vaginosis. Clin. Microbiol. Infect. 15 (2009) 67-74
24. Methods for Antimicrobial Dilution and Disc Susceptibility Testing of Infrequently Isolated or Fastidious Bacteria; Approved Guideline. CLSI document M45-A (2006), Clinical and Laboratory Standards Institute, Wayne, Pa
25. Pigeon R.M., Cuesta E.P., and Gilliland S.E.G. Binding of free bile acids by cells of yogurt starter culture bacteria. J. Dairy Sci. 85 (2002) 2705-2710
26. Rao G.G., Short A., and Carmichael D. CAPD peritonitis caused by vancomycin resistant lactobacilli. Nephrol. Dial. Transplant. 5 (1990) 235-236
27. Sambrook J., and Russell D.W. Molecular Cloning, A Laboratory Manual (2001), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York
28. Schlefeir C.R., Benz R.L., McAlack J., Poupard J., and Calmon J. Lactobacillus acidophilus peritonitis in CAPD. Perit. Dial. Int. 9 (1989) 222-223
29. Strommenger B., Kettlitz C., Werner G., and Witte W. Multiplex PCR assay for simultaneous detection of nine clinically relevant antibiotic resistance genes in Staphylococcus aureus. J. Clin. Microbiol. 41 (2003) 4089-4094
30. Tracevska T., Jansone I., Nodieva A., Marga O., Skenders G., and Baumanis V. Characterisation rpsL, rrs and embB mutations associated with streptomycin and ethambutol resistance in Micobacterium tuberculosis. Res. Microbiol. 155 (2004) 830-840
31. Vásquez A., Jakobsson T., Ahrne S., Forsum U., and Molin G. Vaginal Lactobacillus flora of healthy Swedish women. J. Clin. Microbiol. 40 (2002) 2746-2749
32. Versalovic J., Shortridge D., Kibler K., Griffy M.V., Beyer J., Flamm R.K., Tanaka S.K., Graham D.Y., and Go M.F. Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori. Antimicrob. Agents Chemother. 40 (1996) 477-478
33. Weisblum B. Erythromycin resistance by ribosome modification. Antimicrob. Agents Chemother. 39 (1995) 577-585