Advancement on study of pharmacological action and clinical application of cinobufotalin

International Journal of Ophthalmology

Volumn 9, Issue 7, 2009, Pages 1330-1333

  Wang, Ting Ting ^a,b   Xu, Guo Xing ^b  

^a FUJIAN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Cinobufotalin; Clinical application; Pharmacological action

Indexed keywords

CINOBUFOTALIN; IMMUNOLOGIC AGENT; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; CANCER INHIBITION; DRUG EFFICACY; IMMUNOREGULATION; REVIEW; TRADITIONAL MEDICINE;

EID: 69249184760     PISSN: 16725123     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1672-5123.2009.07.038     Document Type: Review

References (34)

1. Masuda Y, Kawazoe N, Nakajo S, et al. Bufalin induces apoptosis and influences the expression of apoptosis-related genes in human leukemia cells. Leuk Res 1995;19(8):549-556
2. Brown JM, Wouters BG. Apoptosis, p53, and tumor cell sensitivity to anticancer agents. Cancer Res 1999;59(7):1391-1399
3. Lessene G, Czabotar PE, Colman PM. BCL-2 family antagonists for cancer therapy. Nat Rev Drug Discov 2008;7(12):989-1000
4. Hossini AM, Eberle J. Apoptosis induction by Bcl-2 proteins independent of the BH3 domain. Biochem Pharmacol 2008;76(11):1612-1619
5. Watabe M, Kawazoe N, Masuda Y, et al. Bcl-2 protein inhibits bufalin-induced apoptosis through inhibition of mitogen-activated protein kinase activation in human leukemia U937 cells. Cancer Res 1997;57(15):3097-3100 (Pubitemid 27351717)
6. Watabe M, Nakajo S, Yoshida T, et al. Treatment of U937 cells with bufalin induces the translocation of casein kinase 2 and modulates the activity of topoisomerase II prior to the induction of apoptosis. Cell Growth Differ 1997;8(8):871-879 (Pubitemid 27355460)
7. Kurosawa M, Tani Y, Nishimura S, et al. Distinct PKC isozymes regulate bufalin-induced differentiation and apoptosis in human monocytic cells. Am J Physiol Cell Physiol 2001;280(3):459-464 (Pubitemid 32466807)
8. Kurosawa M, Numazawa S, Tani Y, et al. ERK signaling mediates the induction of inflammatory cytokines by bufalin in human monocytic cells. Am J Physiol Cell Physiol 2000;278(3):500-508 (Pubitemid 30154929)
9. +-ATPase inhibition in the early changes in proto-oncogene expression. Biochem Pharmacol 1996;52(2):321-329
10. Yamada K, Hino K, Tomoyasu S, et al. Enhancement by bufalin of retinoic acid-induced diferentiation of acute promyelocytic leukemia cells in primary culture. Leuk Res 1998;22(7):589-595 (Pubitemid 28327461)
11. Bolontrade MF, Stern MC, Binder RL, et al. Angiogensis is an early event in the devlopment of chemically induced skintumors. Carcinogenesis 1998;19(12):2107-2113
12. Lee DY, Yasuda M, Yamamoto T, et al. Bufalin inhibits endothelial cell proliferation and angiogenesis in vitro. Life Sci 1997;60(2):127-134 (Pubitemid 27022720)
13. Efferth T, Davey M, Olbrich A, et al. Activity of drugs from traditional Chinese medicine toward sensitive and MDR1 or MRP1 overexpression multidrug-resistant human CCRF-CEM leukemia cells. Blood Cells Molecules and Diseases 2002;28(2):160-168 (Pubitemid 34743750)