Implantable cardioverter defibrillators: Do women fare worse than men? gender comparison in the INTRINSIC RV trial

Journal of Cardiovascular Electrophysiology

Volumn 20, Issue 9, 2009, Pages 973-978

  Russo, Andrea M ^a,f   Day, John D ^b   Stolen, Kira ^c   Mullin, Christopher M ^d   Doraiswamy, Vinayak ^c   Lerew, Darin L ^c   Olshansky, Brian ^e  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b INTERMOUNTAIN MEDICAL CENTER   (United States)

^c Boston Scientific CRM   (United States)

^d Integra Group   (United States)

^e UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^f Division of Female Pelvic Medicine and Reconstructive Surgery   (United States)

Author keywords

Heart failure; Implantable cardioverter defibrillator; Mortality; Sudden death; Women

Indexed keywords

AMIODARONE; ANTIARRHYTHMIC AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; SPIRONOLACTONE;

AGED; ARTICLE; CARDIOMYOPATHY; CLINICAL TRIAL; CONGESTIVE HEART FAILURE; DEFIBRILLATOR; DIABETES MELLITUS; FEMALE; FOLLOW UP; GENDER; HEART FAILURE; HEART MUSCLE ISCHEMIA; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE TACHYCARDIA; HOSPITALIZATION; HUMAN; HYPERLIPIDEMIA; ISCHEMIC HEART DISEASE; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; SURVIVAL; TREATMENT OUTCOME;

AGED; DEFIBRILLATORS, IMPLANTABLE; ELECTRIC COUNTERSHOCK; FEMALE; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; RISK ASSESSMENT; RISK FACTORS; SEX DISTRIBUTION; SURVIVAL ANALYSIS; SURVIVAL RATE; TREATMENT OUTCOME; UNITED STATES;

EID: 69249184388     PISSN: 10453873     EISSN: 15408167     Source Type: Journal    
DOI: 10.1111/j.1540-8167.2009.01489.x     Document Type: Article

References (35)

1. Kannel WB, Schatzkin A : Sudden death: Lessons from subsets in population studies. J Am Coll Cardiol 1985 5 : 141B 149B.
2. Cupples LA, Gagnon DR, Kannel WB : Long-and short-term risk of sudden coronary death. Circulation 1992 85 (Suppl 1 I11 I18.
3. Kannel WB, Wilson PW, D'Agostino RB, Cobb J : Sudden coronary death in women. Am Heart J 1998 136 : 205 212.
4. Kim C, Fahrenbruch CE, Cobb LA, Eisenberg MS : Out-of-hospital cardiac arrest in men and women. Circulation 2001 104 2699 2703.
5. Wigginton JG, Pepe PE, Bedolla JP, DeTamble LA, Atkins JM : Sex-related differences in the presentation and outcome of out-of-hospital cardiopulmonary arrest: A multiyear, prospective, population-based study. Crit Care Med 2002 30 (Suppl 4 S131 S136.
6. Herlitz J, Rundqvist S, Bang A, Aune S, Lundström G, Ekström L, Lindkvist J : Is there a difference between women and men in characteristics and outcome after in hospital cardiac arrest Resuscitation 2001 49 : 15 23.
7. Engelstein ED, Friedman PL, Yao Q, Coromilas J, Beckman KJ, Buxton AE, Flynn D, Firth B, Delamaga H, Ledingham R, Schron EB : Gender differences in patients with life-threatening ventricular arrhythmias: Impact on treatment and survival in the AVID trial. Circulation 1997 96 (Suppl I 720.
8. Pires LA, Sethuraman B, Guduguntla VD, Todd KM, Yamasaki H, Ravi S : Outcome of women versus men with ventricular tachyarrhythmias treated with the implantable cardioverter defibrillator. J Cardiovasc Electrophysiol 2002 : 563 568.
9. Lampert R, McPherson CA, Clancy JF, Caulin-Glaser TL, Rosenfeld LE, Batsford WP : Gender differences in ventricular arrhythmia recurrence in patients with coronary artery disease and implantable cardioverter- defibrillators. J Am Coll Cardiol 2004 43 : 2293 2299.
10. Russo AM, Stamato NJ, Lehmann MH, Hafley GE, Lee KL, Pieper K, Buxton AE : Influence of gender on arrhythmia characteristics in the Multicenter Unsustained Tachycardia Trial. J Cardiovasc Electrophysiol 2004 5 : 993 998.
11. Zareba W, Moss AJ, Jackson HW, Wilber DJ, Ruskin JN, McNitt S, Brown M, Wang H : Clinical course and implantable cardioverter defibrillator therapy in postinfarction women with severe left ventricular dysfunction. J Cardiovasc Electrophysiol 2005 16 : 1265 1270.
12. Russo AM, Poole JE, Mark DB, Anderson J, Hellkamp AS, Lee KL, Johnson GW, Domanski M, Bardy GH : Primary prevention with defibrillator therapy in women: Results from the Sudden Cardiac Death in Heart Failure Trial. J Cardiovasc Electrophysiol 2008 19 : 720 724.
13. Bardy GH, Lee KL, Mark DB, Poole JE, Packer DL, Boineau R, Domanski M, Troutman C, Anderson J, Johnson G, McNulty SE, Clapp-Channing N, Davidson-Ray LD, Fraulo ES, Fishbein DP, Luceri RM, Ip JH : Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med 2005 352 : 225 237.
14. Kadish A, Dyer A, Daubert JP, Daubert JP, Quigg R, Estes NA, Anderson KP, Calkins H, Hoch D, Goldberger J, Shalaby A, Sanders WE, Schaechter A, Levine JH : Defibrillator implantation in patients with nonischemic dilated cardiomyopathy. N Engl J Med 2004 350 : 2151 2158.
15. Albert CM, Quigg R, Saba S, Estes NA III., Shaechter A, Subacius H, Howard A, Levine J, Kadish A : Sex differences in outcome after implantable cardioverter defibrillator implantation in nonischemic cardiomyopathy. Am Heart J 2008 156 : 367 372.
16. Olshansky B, Day J, McGuire M, Hahn S, Brown S, Lerew DR : Reduction of right ventricular pacing in patients with dual-chamber ICDs. Pacing Clin Electrophysiol 2006 29 : 237 243.
17. Olshansky B, Day JD, Moore S, Gering L, Rosenbaum M, McGuire M, Brown S, Lerew DR : Is dual chamber programming inferior to single chamber programming in an implantable cardioverter defibrillator? Results of the Intrinsic RV (Inhibition of Unnecessary RV Pacing with AVSH in ICDs) Study. Circulation 2007 115 : 9 16.
18. Moss AJ, Hall WJ, Cannom DS, Daubert JP, Higgins SL, Klein H, Levine JH, Saksena S, Waldo AL, Wilber D, Brown MW, Heo M : Improved survival with an implanted defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med 1996 335 : 1933 1940.
19. Moss AJ, Zareba W, Hall J, Klein H, Wilber DJ, Cannom DS, Daubert JP, Higgins SL, Brown MW, Andrews ML : Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med 2002 346 : 877 883.
20. Curtis LH, Al-Khatib SM, Shea AM, Hammill BG, Hernandez AF, Schulman KA : Sex differences in the use of implantable cardioverter-defibrillators for primary and secondary prevention of sudden cardiac death. JAMA 2007 298 : 1517 1524.
21. Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). Lancet 1999 353 : 2001 2007.
22. Packer M, Coats AJ, Fowler MB, Katus HA, Krum H, Mohacsi P, Rouleau JL, Tendera M, Castaigne A, Roecker EB, Schultz MK, DeMets DL : Effect of carvedilol on survival in severe chronic heart failure. N Engl J Med 2001 344 : 1651 1658. (Pubitemid 32479962)
23. Simon T, Mary-Krause M, Funck-Brentano C, Jaillon P : Sex differences in the prognosis of congestive heart failure: Results from the Cardiac Insufficiency Bisoprolol Study (CIBIS II). Circulation 2001 103 : 375 380.
24. Ng AC, Wong HS, Young AS, Sindone AP : Impact of gender on outcomes in chronic systolic heart failure. Int J Cardiol 2007 117 : 214 221.
25. Roger VL, Weston SA, Redfield MM, Hellermann-Homan JP, Killian J, Yawn BP, Jacobsen SJ : Trends in heart failure incidence and survival in a community-based population. JAMA 2004 292 : 344 350.
26. Bursi F, Weston SA, Redfield MM, Jacobsen SJ, Pakhomov S, Nkomo VT, Meverden RA, Roger VL : Systolic and diastolic heart failure in the community. JAMA 2006 296 : 2209 2216.
27. Albert CM, McGovern BA, Newell JB, Ruskin JN : Sex differences in cardiac arrest survivors. Circulation 1996 93 : 1170 1176.
28. Freedman RA, Swerdlow CD, Soderholm-Difatte V, Mason JW : Prognostic significance of arrhythmia inducibility or noninducibility at initial EP study in survivors of cardiac arrest : Am J Cardiol 1988 61 : 578 582.
29. Horton HL, Marinchak RA, Rials SJ, Kowey PR : Gender differences in device therapy for malignant ventricular arrhythmias. Arch Intern Med 1995 155 : 2342 2345.
30. Kudenchuk PJ, Bardy GH, Poole JE, Dolack GL, Gleva MJ, Reddy R, Jones GK, Troutman C, Anderson J, Johnson G : Malignant sustained ventricular tachyarrhythmias in women: Characteristics and outcome of treatment with an implantable cardioverter defibrillator. J Cardiovasc Electrophysiol 1997 8 : 2 10.
31. Davis DR, Tang AS, Lemery R, Green MS, Gollob MH, Birnie DH : Influence of gender on ICD implantation for primary and secondary prevention of sudden cardiac death. Europace 2006 8 : 1054 1056.
32. Dolack GL : Clinical predictors of implantable cardioverter defibrillator shocks: Results of the CASCADE (Cardiac Arrest in Seattle, Conventional versus Amiodarone Drug Evaluation). Am J Cardiol 1994 73 : 237 241.
33. Lessmeier TJ, Lehmann MH, Steinman RT, Fromm BS, Akhtar M, Calkins H, DiMarco JP, Epstein AE, Estes NA, Fogoros RN : Implantable cardioverter defibrillator therapy in 300 patients with coronary artery diseases presenting exclusively with ventricular fibrillation. Am Heart J 1994 128 : 211 218.
34. Singh JP, Hall WJ, McNitt S, Wang H, Daubert JP, Zareba W, Ruskin JN, Moss AJ : Factors influencing appropriate firing of the implanted defibrillator for ventricular tachycardia/fibrillation: Findings from the Multicenter Automatic Defibrillator Implantation Trial II (MADIT-II). J Am Coll Cardiol 2005 46 : 1712 1720.
35. Gelman A, Hill J : Data Analysis Using Regression and Multilevel/Hierarchical Models. New York : Cambridge University Press, 2006.