Exhaled nitric oxide as a marker of asthma control in smoking patients

European Respiratory Journal

Volumn 33, Issue 6, 2009, Pages 1295-1301

  Michils, A ^a   Louis, R ^b   Peche R ^c   Baldassarre, S ^a   Van Muylem, A ^a  

^a ERASME HOSPITAL   (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c CHU Andre Vesale   (Belgium)

Author keywords

Asthma control; Exhaled nitric oxide; Tobacco smoking

Indexed keywords

BECLOMETASONE DIPROPIONATE; BIOLOGICAL MARKER; NITRIC OXIDE;

ADULT; ARTICLE; ASTHMA; ASTHMA CONTROL QUESTIONNAIRE; CIGARETTE SMOKING; CLINICAL TRIAL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIAGNOSTIC VALUE; DRUG MEGADOSE; EXHALATION; FEMALE; GOLD STANDARD; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PATIENT ASSESSMENT; PREDICTION; PRIORITY JOURNAL; QUESTIONNAIRE; SCORING SYSTEM; SMOKING;

ADULT; ANTI-ASTHMATIC AGENTS; ASTHMA; BIOLOGICAL MARKERS; CHI-SQUARE DISTRIBUTION; CROSS-SECTIONAL STUDIES; EXHALATION; FEMALE; HUMANS; LUMINESCENCE; MALE; NITRIC OXIDE; PREDICTIVE VALUE OF TESTS; QUESTIONNAIRES; RESPIRATORY FUNCTION TESTS; ROC CURVE; SMOKING;

EID: 69249157719     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00154008     Document Type: Article

References (30)

1. Jones SL, Kittelson J, Cowan JO, et al. The predictive value of exhaled nitric oxide measurements in assessing changes in asthma control. Am J Respir Crit Care Med 2001; 164: 738-743.
2. Smith AD, Cowan JO, Brassett KP, et al. Use of exhaled nitric oxide measurements to guide treatment in chronic asthma. N Engl J Med 2005; 352: 2163-2173.
3. Shaw DE, Berry MA, Thomas M, et al. The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial. Am J Respir Crit Care Med 2007; 176: 231-237.
4. Turner S. Exhaled nitric oxide in the diagnosis and management of asthma. Curr Opin Allergy Clin Immunol 2008; 8: 70-76.
5. Szefler SJ, Mitchell H, Sorkness CA, et al. Management of asthma based on exhaled nitric oxide in addition to guideline-based treatment for inner-city adolescents and young adults: a randomised controlled trial. Lancet 2008; 372: 1065-1072.
6. Olin AC, Rosengren A, Thelle DS, et al. Height, age, and atopy are associated with fraction of exhaled nitric oxide in a large adult general population sample. Chest 2006; 130: 1319-1325.
7. Taylor DR, Pijnenburg MW, Smith AD, et al. Exhaled nitric oxide measurements: clinical application and interpretation. Thorax 2006; 61: 817-827.
8. Persson MG, Zetterstrom O, Agrenius V, et al. Single-breath nitric oxide measurements in asthmatic patients and smokers. Lancet 1994; 343: 146-147.
9. Kharitonov SA, Robbins RA, Yates D, et al. Acute and chronic effects of cigarette smoking on exhaled nitric oxide. Am J Respir Crit Care Med 1995; 152: 609-612.
10. Verleden GM, Dupont LJ, Verpeut AC, et al. The effect of cigarette smoking on exhaled nitric oxide in mild steroid-naive asthmatics. Chest 1999; 116: 59-64.
11. Hogman M, Holmkvist T, Walinder R, et al. Increased nitric oxide elimination from the airways after smoking cessation. Clin Sci (Lond) 2002; 103: 15-19.
12. Horvath I, Donnelly LE, Kiss A, et al. Exhaled nitric oxide and hydrogen peroxide concentrations in asthmatic smokers. Respiration 2004; 71: 463-468.
13. McSharry CP, McKay IC, Chaudhuri R, et al. Short and long-term effects of cigarette smoking independently influence exhaled nitric oxide concentration in asthma. J Allergy Clin Immunol 2005; 116: 88-93.
14. Travers J, Marsh S, Aldington S, et al. Reference ranges for exhaled nitric oxide derived from a random community survey of adults. Am J Respir Crit Care Med 2007; 176: 238-242.
15. Dressel H, de la Motte D, Reichert J, et al. Exhaled nitric oxide: independent effects of atopy, smoking, respiratory tract infection, gender and height. Respir Med 2008; 102: 962-969.
16. Gaston B, Drazen JM, Loscalzo J, et al. The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med 1994; 149: 538-551.
17. Thomson NC, Chaudhuri R, Livingston E. Asthma and cigarette smoking. Eur Respir J 2004; 24: 822-833.
18. Michils A, Baldassarre S, Van Muylem A. Exhaled nitric oxide and asthma control: a longitudinal study in unselected patients. Eur Respir J 2008; 31: 539-546.
19. Juniper EF, O'Byrne PM, Guyatt GH, et al. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999; 14: 902-907.
20. Global initiative for Asthma. Global strategy for asthma management and prevention: NHLBI/WHO Workshop Report. NHLBI Publication 02-3659. Washington, Government Printing Office, 2002.
21. Siroux V, Pin I, Oryszczyn MP, et al. Relationships of active smoking to asthma and asthma severity in the EGEA study. Epidemiological study on the Genetics and Environment of Asthma. Eur Respir J 2000; 15: 470-477.
22. Juniper EF, Bousquet J, Abetz L, et al. Identifying "well-controlled" and "not well-controlled" asthma using the Asthma Control Questionnaire. Respir Med 2006; 100: 616-621.
23. Juniper EF, Svensson K, Mork AC, et al. Measurement properties and interpretation of three shortened versions of the asthma control questionnaire. Respir Med 2005; 99: 553-558.
24. American Thoracic Society/European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 2005; 171: 912-930.
25. Youden WJ. Index for rating diagnostic tests. Cancer 1950; 3: 32-35.
26. Jatakanon A, Lim S, Kharitonov SA, et al. Correlation between exhaled nitric oxide, sputum eosinophils, and methacholine responsiveness in patients with mild asthma. Thorax 1998; 53: 91-95.
27. Chalmers GW, Macleod KJ, Little SA, et al. Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma. Thorax 2002; 57: 226-230.
28. Lazarus SC, Chinchilli VM, Rollings NJ, et al. Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma. Am J Respir Crit Care Med 2007; 175: 783-790.
29. Jatakanon A, Kharitonov S, Lim S, et al. Effect of differing doses of inhaled budesonide on markers of airway inflammation in patients with mild asthma. Thorax 1999; 54: 108-114.
30. Jones SL, Herbison P, Cowan JO, et al. Exhaled NO and assessment of anti-inflammatory effects of inhaled steroid: dose-response relationship. Eur Respir J 2002; 20: 601-608.