Cell density effect in the baculovirus-insect cells system: A quantitative analysis of energetic metabolism

Biotechnology and Bioengineering

Volumn 104, Issue 1, 2009, Pages 162-180

  Bernal, Vicente ^a   Carinhas, Nuno ^a   Yokomizo, Adriana Y ^a   Carrondo, Manuel J T ^a,b   Alves, Paula M ^a  

^a INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^b UNIVERSIDADE NOVA DE LISBOA   (Portugal)

Author keywords

Baculovirus production; Cell density effect; Metabolic burden; Metabolic flux analysis; Protein production; Spodoptera frugiperda

Indexed keywords

BACULOVIRUS PRODUCTION; CELL DENSITY EFFECT; METABOLIC BURDEN; METABOLIC FLUX ANALYSIS; PROTEIN PRODUCTION; SPODOPTERA FRUGIPERDA;

AMINATION; AMINES; AMINO ACIDS; BIOCHEMISTRY; CELL MEMBRANES; METABOLISM; OPTIMIZATION; ORGANIC ACIDS; PATHOLOGY;

CELL CULTURE;

AMINO ACID; GLUTAMINE; MALIC ACID; NITROGEN; PYRUVIC ACID;

AMINO ACID METABOLISM; ANIMAL CELL; ARTICLE; BACULOVIRUS EXPRESSION SYSTEM; CARBON SOURCE; CELL CYCLE ARREST; CELL DENSITY; CELL GROWTH; CELL METABOLISM; CITRIC ACID CYCLE; CONTROLLED STUDY; DOWN REGULATION; ENERGY TRANSFER; GLYCOLYSIS; INSECT CELL; METABOLIC ENGINEERING; METABOLIC REGULATION; NITROGEN METABOLISM; NONHUMAN; OXIDATION REDUCTION REACTION; PENTOSE PHOSPHATE CYCLE; STOICHIOMETRY;

ANIMALS; BACULOVIRIDAE; CELL COUNT; CELL LINE; ENERGY METABOLISM; METABOLIC NETWORKS AND PATHWAYS; SPODOPTERA;

HEXAPODA; SPODOPTERA FRUGIPERDA;

EID: 69249132543     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.22364     Document Type: Article

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