Radiation-induced thyroid changes: A retrospective and a prospective view

European Journal of Cancer

Volumn 45, Issue 14, 2009, Pages 2546-2551

  Massimino, Maura ^a   Gandola, Lorenza ^a   Mattavelli, Franco ^a   Pizzi, Natalia ^a   Seregni, Ettore ^a   Pallotti, Federica ^a   Spreafico, Filippo ^a   Marchianò, Alfonso ^a   Terenziani, Monica ^a   Cefalo, Graziella ^a   Biassoni, Veronica ^a   Meazza, Cristina ^a   Trecate, Giovanna ^a   Collini, Paola ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Childhood radiotherapy; Iatrogenic hypothyroidism; Second tumours; Thyroid late effects; Thyroid nodules

Indexed keywords

THYROGLOBULIN; THYROTROPIN;

ADULT; ARTICLE; FEMALE; FOLLOW UP; HUMAN; HYPOTHYROIDISM; IRRADIATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; THYROID CARCINOMA; THYROID NODULE; ULTRASOUND;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; HYPOTHYROIDISM; INFANT; MALE; NEOPLASMS, RADIATION-INDUCED; NEOPLASMS, SECOND PRIMARY; PROSPECTIVE STUDIES; RADIOTHERAPY, ADJUVANT; RETROSPECTIVE STUDIES; THYROID FUNCTION TESTS; THYROID GLAND; THYROID NEOPLASMS; THYROID NODULE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 69249098587     PISSN: 09598049     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejca.2009.06.009     Document Type: Article

References (35)

1. Schneider A.B., Ron E., Lubin J., Stovall M., and Gierlowski T.C. Dose-response relationships for radiation-induced thyroid cancer and thyroid nodules: evidence of the prolonged effects of radiation on the thyroid. J Clin Endocrinol Metab 77 (1993) 362-369
2. Ron E., Lubin J.H., Shore R.E., et al. Thyroid cancer after exposure to external radiation: A pooled analysis of seven studies. Radiat Res 141 (1995) 259-277
3. Wemeau J.L., Caron P., Schvartz C., et al. Effects of thyroid-stimulating hormone suppression with levothyroxine in reducing the volume of solitary thyroid nodules and improving extranodular nonpalpable changes: a randomized, double-blind, placebo-controlled trial by the French Thyroid Research Group. J Clin Endocrinol Metab 87 (2002) 4928-4934
4. Crile G., Antunez A.R., Esseltyn C.B., et al. The advantages of subtotal thyroidectomy and suppression of TSH in the primary treatment of papillary carcinoma of the thyroid. Cancer 55 (1985) 2691-2697
5. Cox R. Regression models and life tables. J Royal Stat Soc 34 (1972) 187-202
6. Kaloumenou I., Alevizaki M., Ladopoulos C., et al. Thyroid volume and echostructure in schoolchildren living in an iodine-replete area: relation to age, pubertal stage, and body mass index. Thyroid 17 (2007) 875-881
7. Duffy B.J., and Fitzgerald P.J. Thyroid cancer in childhood and adolescence. Report of 28 cases. J Clin Endocrinol Metab 10 (1950) 1296-1308
8. Ron E., Modan B., Preston D., Alfandary E., Stovall M., and Boice J.D. Thyroid neoplasia following low-dose radiation in childhood. Radiat. Res 120 (1989) 516-531
9. Ron E., and Modan B. Benign and malignant thyroid neoplasms after childhood irradiation for tinea capitis. J Natl Cancer Inst 65 (1980) 7-11
10. Shalet S.M., Rosenstock J.D., Beardwell C.G., Pearson D., and Jones P.H. Thyroid dysfunction following external radiation to the neck for Hodgkin's disease in childhood. Clin Radiol 28 (1977) 511-515
11. Hancock S.L., McDougall I.R., and Constine L.S. Thyroid abnormalities after therapeutic external irradiation. Int J Radiat Oncol Biol Phys 31 (1995) 1165-1170
12. Constine L.S., Donaldson S.S., McDougall I.R., Cox R.S., Link M.P., and Kaplan H.S. Thyroid dysfunction after radiotherapy in children with Hodgkin's disease. Cancer 53 (1984) 878-883
13. Ron E., Lubin J.H., Shore R.E., et al. Thyroid cancer after exposure to external radiation: a pooled analysis of seven studies. Radiat Res 141 (1995) 259-277
14. Goldberg R.C., Lindsay S., and Feller D.D. Histopathological changes induced in the normal thyroid and other tissues of the rat by internal radiation with various doses of radioactive iodine. Endocrinology 46 (1950) 72-90
15. Nishiyama K., Tanaka E., Tarui Y., et al. A prospective analysis of subacute thyroid dysfunction after neck irradiation. Int J Radiat Oncol Biol Phys 34 (1996) 439-444
16. Van Santen H.M., Van Dijk J.E., and Rodermond H. Et al. The effect of cervical X-irradiation on activity index of thyrocytes and plasma TSH: a pre-clinical model for radiation-induced thyroid damage. J Endocrinol Invest 28 (2005) 261-269
17. Fuks Z., Glatstein E., Marsa G.W., Bagshaw M.A., and Kaplan H.S. Long-tem effects of external radiation on the pituitary and thyroid glands. Cancer 37 suppl 2 (1976) 1152-1161
18. Sutcliffe S.B., Chapman R., and Wriley P.F.M. Cyclical combination chemotherapy and thyroid function in patients with advanced Hodgkin's disease. Med Pediatr. Oncol 9 (1981) 439-448
19. Hancock S.L., Cox R.S., and McDougall I.R. Thyroid diseases after treatment for Hodgkin's disease. N Engl J Med 325 (1991) 599-605
20. Stewart R.S., David C.L., Eftekhari F., Ried H.L., Fuller L.M., and Fornage B.D. Thyroid gland: US in patients with Hodgkin disease treated with radiation therapy in childhood. Radiology 172 (1989) 159-163
21. Fogefeld L., Wiviott M.B.T., Shore-Freedman E., Blend M., Bkeman C., Pinsky S., and Schneider A.B. Recurrence of thyroid nodules after surgical removal in patients irradiated for benign conditions. N Engl J Med 320 (1989) 835-840
22. Crom D.B., Kaste S.C., Tubergen D.G., Greenwald C.A., Sharp G.B., and Hudson M.H. Ultrasonography for thyroid screening after head and neck irradiation in childhood survivors. Med. Pediatr. Oncol. 28 (1997) 15-21
23. Wemeau J.L., Caron P., Schvartz C., Schlienger J.L., Orgiazzi J., Cousty C., et al. Effects of thyroid-stimulating hormone suppression with levothyroxine in reducing the volume of solitary thyroid nodules and improving extranodular nonpalpable changes: a randomized, double-blind, placebo-controlled trial by the French Thyroid Research Group. J Clin Endocrinol Metab 87 (2002) 4928-4934
24. Koc M., Ersoz H.O., Akpinar I., Gogas-Yavuz D., Deyneli O., and Akalin S. Effect of low- and high-dose levothyroxine on thyroid nodule volume: a crossover placebo-controlled trial. Clinical Endocrinology 57 (2002) 621-628
25. Mihailescu D.V., and Schneider A.B. Size, number and distribution of thyroid nodules and their risk of malignancy in radiation-exposed patients who underwent surgery. J Clin Endocrin Metab (2008) [ahead of print April 1]
26. Tucker M.A., Morris Jones P.H., Boice J.D., et al. Therapeutic radiation at a young age is linked to secondary thyroid cancer. Cancer Res 51 (1991) 2885-2888
27. Sigurdson A.J., Ronckers C.M., Mertens A.C., et al. Primary thyroid cancer after a first tumour in childhood (the Childhood Cancer Survivor Study): a nested case-control study. Lancet 365 (2005) 2014-2023
28. Nikiforov Y., and Gnepp D.R. Pediatric thyroid cancer after the Chernobyl disaster. Cancer 74 (1994) 748-766
29. Collini P., Mattavelli F., Pellegrinelli A., Barisella M., Ferrari A., and Massimino M. Papillary carcinoma of the thyroid gland of childhood and adolescence. morphologic subtypes, biologic behavior and prognosis. A clinicopathologic study of 42 sporadic cases treated at a single institution during a 30-year period. Am J Surg Pathol 30 (2006) 1420-1426
30. Black P., Straaten A., and Gutjahr G. Secondary thyroid carcinoma after treatment for childhood cancer. Med Pediatr Oncol 31 (1998) 91-95
31. Acharya S., Sarafoglou K., LaQuaglia M., Lindsley S., Gerald W., Wollner N., Tan C., and Sklar C. Thyroid neoplasms after therapeutic radiation for malignancies during childhood or adolescence. Cancer (2003) 2397-2403
32. St. Clair W.H., Adams J., Bues M., et al. Advantage of protons compared to conventional X-ray or IMRT in the treatment of a pediatric patient with medulloblastoma. Int J Radiat Oncol Biol Phys 58 (2004) 727-734
33. Jereczek-Fossa B.A., Alterio D., Jassem J., Gibelli B., Tradati N., and Orecchia R. Radiotherapy-induced thyroid disorders. Cancer Treat Rev 30 (2004) 369-384
34. Hall E.J., and Wuu C.S. Radiation induced second cancers: the impact of £D-CRT and IMRT. Int J Radiat Oncol Biol Phys 56 (2003) 83-88
35. Massimino M., Gandola L., Collini P., et al. Thyroid-stimulating hormone suppression for protection against hypothyroidism due to craniospinal irradiation for childhood medulloblastoma/primitive neuroectodermal tumor. Int J Radiat Oncol Biol Phys 69 (2007) 404-410