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Volumn 18, Issue 5, 2009, Pages 381-383

Sildenafil Treatment of Subacute Ischemic Stroke: A Safety Study at 25-mg Daily for 2 Weeks

Author keywords

safety; sildenafil; Stroke

Indexed keywords

SILDENAFIL;

EID: 69149103302     PISSN: 10523057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2009.01.007     Document Type: Article
Times cited : (43)

References (15)
  • 1
    • 0036843061 scopus 로고    scopus 로고
    • Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats
    • Zhang R., Wang Y., Zhang L., et al. Sildenafil (Viagra) induces neurogenesis and promotes functional recovery after stroke in rats. Stroke 33 (2002) 2675-2680
    • (2002) Stroke , vol.33 , pp. 2675-2680
    • Zhang, R.1    Wang, Y.2    Zhang, L.3
  • 2
    • 0037458918 scopus 로고    scopus 로고
    • Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat
    • Zhang R., Wang L., Zhang L., et al. Nitric oxide enhances angiogenesis via the synthesis of vascular endothelial growth factor and cGMP after stroke in the rat. Circ Res 92 (2003) 308-313
    • (2003) Circ Res , vol.92 , pp. 308-313
    • Zhang, R.1    Wang, L.2    Zhang, L.3
  • 3
    • 16844372455 scopus 로고    scopus 로고
    • Functional recovery in aged and young rats after embolic stroke: Treatment with a phosphodiesterase type 5 inhibitor
    • Zhang L., Zhang R.L., Wang Y., et al. Functional recovery in aged and young rats after embolic stroke: Treatment with a phosphodiesterase type 5 inhibitor. Stroke 36 (2005) 847-852
    • (2005) Stroke , vol.36 , pp. 847-852
    • Zhang, L.1    Zhang, R.L.2    Wang, Y.3
  • 4
    • 24944455102 scopus 로고    scopus 로고
    • Activation of the PI3-K/Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone
    • Wang L., Gang Zhang Z., Lan Zhang R., et al. Activation of the PI3-K/Akt pathway mediates cGMP enhanced-neurogenesis in the adult progenitor cells derived from the subventricular zone. J Cereb Blood Flow Metab 25 (2005) 1150-1158
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 1150-1158
    • Wang, L.1    Gang Zhang, Z.2    Lan Zhang, R.3
  • 5
    • 33646365892 scopus 로고    scopus 로고
    • Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia
    • Zhang R.L., Zhang Z., Zhang L., et al. Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia. J Neurosci Res 83 (2006) 1213-1219
    • (2006) J Neurosci Res , vol.83 , pp. 1213-1219
    • Zhang, R.L.1    Zhang, Z.2    Zhang, L.3
  • 6
    • 33846191628 scopus 로고    scopus 로고
    • Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke
    • Li L., Jiang Q., Zhang L., et al. Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke. Brain Res 1132 (2007) 185-192
    • (2007) Brain Res , vol.1132 , pp. 185-192
    • Li, L.1    Jiang, Q.2    Zhang, L.3
  • 7
    • 33750317276 scopus 로고    scopus 로고
    • Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke
    • Zhang L., Zhang Z., Zhang R.L., et al. Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke. Brain Res 1118 (2006) 192-198
    • (2006) Brain Res , vol.1118 , pp. 192-198
    • Zhang, L.1    Zhang, Z.2    Zhang, R.L.3
  • 8
    • 33744921637 scopus 로고    scopus 로고
    • Recovery in a patient with locked-in syndrome
    • Silver B., Grover K.M., Arcila X., et al. Recovery in a patient with locked-in syndrome. Can J Neurol Sci 33 (2006) 246-249
    • (2006) Can J Neurol Sci , vol.33 , pp. 246-249
    • Silver, B.1    Grover, K.M.2    Arcila, X.3
  • 9
    • 0028783948 scopus 로고
    • Tissue plasminogen activator for acute ischemic stroke
    • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group
    • The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 333 (1995) 1581-1587
    • (1995) N Engl J Med , vol.333 , pp. 1581-1587
  • 10
    • 34247188553 scopus 로고    scopus 로고
    • PREVAIL Investigators. The efficacy and safety of enoxaparin versus unfractionated heparin for the prevention of venous thromboembolism after acute ischemic stroke (PREVAIL study): An open-label randomized comparison
    • Sherman D.G., Albers G.W., Bladin C., et al. PREVAIL Investigators. The efficacy and safety of enoxaparin versus unfractionated heparin for the prevention of venous thromboembolism after acute ischemic stroke (PREVAIL study): An open-label randomized comparison. Lancet 369 (2007) 1347-1355
    • (2007) Lancet , vol.369 , pp. 1347-1355
    • Sherman, D.G.1    Albers, G.W.2    Bladin, C.3
  • 11
    • 69149104476 scopus 로고    scopus 로고
    • Viagra (sildenafil citrate) Information. Available from:, Accessed April 7, 2008
    • Viagra (sildenafil citrate) Information. US Food and Drug Administration. Viagra (sildenafil citrate) Information. Available from: http://www.fda.gov/cder/consumerinfo/viagra/default.htm. Accessed April 7, 2008.
    • Viagra (sildenafil citrate) Information. US Food and Drug Administration
  • 12
    • 21744438514 scopus 로고    scopus 로고
    • Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension
    • Paul G.A., Gibbs J.S.R., Boobis A.R., et al. Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension. Br J Clin Pharmacol 60 (2005) 107-112
    • (2005) Br J Clin Pharmacol , vol.60 , pp. 107-112
    • Paul, G.A.1    Gibbs, J.S.R.2    Boobis, A.R.3
  • 13
    • 0036121963 scopus 로고    scopus 로고
    • Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: Absolute bioavailability, food effects and dose proportionality
    • (suppl)
    • Nichols D.J., Muirhead G.J., and Harness J.A. Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: Absolute bioavailability, food effects and dose proportionality. Br J Clin Pharmacol 53 (2002) 5S-12S (suppl)
    • (2002) Br J Clin Pharmacol , vol.53
    • Nichols, D.J.1    Muirhead, G.J.2    Harness, J.A.3
  • 14
    • 0036118848 scopus 로고    scopus 로고
    • Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafil citrate
    • (suppl)
    • Muirhead G.J., Rance D.J., Walker D.K., et al. Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafil citrate. Br J Clin Pharmacol 53 (2002) 13S-20S (suppl)
    • (2002) Br J Clin Pharmacol , vol.53
    • Muirhead, G.J.1    Rance, D.J.2    Walker, D.K.3
  • 15
    • 28244434361 scopus 로고    scopus 로고
    • Introduction to the pharmacokinetics and pharmacodynamics of sildenafil citrate
    • (suppl)
    • Edwards G., and Muirhead G. Introduction to the pharmacokinetics and pharmacodynamics of sildenafil citrate. Br J Clin Pharmacol 53 (2002) 1S-3S (suppl)
    • (2002) Br J Clin Pharmacol , vol.53
    • Edwards, G.1    Muirhead, G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.