Mammography - Oncogenecity at low doses

Journal of Radiological Protection

Volumn 29, Issue 2, 2009, Pages

  Heyes, G J ^a   Mill, A J ^b   Charles, M W ^b  

^a UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACCELERATING VOLTAGES; ATOMIC BOMB SURVIVORS; ATOMIC BOMBS; BIOLOGICAL EFFECTIVENESS; BREAST CANCER; BREAST SCREENING; CANCER INDUCTION; ENERGY X-RAYS; GENETIC SENSITIVITY; GENETIC SUSCEPTIBILITY; HIGH DOSE; HIGH-ENERGY ELECTRON; HIGH-ENERGY SOURCES; HUMAN CELL LINES; HUMAN CELLS; IN-VITRO; LOW DOSE; LOW DOSE RATE; LOW ENERGY X RAYS; LOW-DOSE EXPOSURES; MAMMOGRAPHIC; RADIATION RISK; RADIATION-INDUCED; RELATIVE BIOLOGICAL EFFECTIVENESS; RISK/BENEFIT ANALYSIS; X-RAY ENERGIES; X-RAY SOURCES;

APPROXIMATION THEORY; ATOMIC SPECTROSCOPY; BOMBS (ORDNANCE); CELL CULTURE; DOSIMETRY; HIGH ENERGY PHYSICS; MAGNETIC RESONANCE IMAGING; RADIOTHERAPY; RESONANCE; RISK ASSESSMENT; RISK MANAGEMENT;

X RAYS;

BREAST TUMOR; CELL TRANSFORMATION; FEMALE; HUMAN; MAMMOGRAPHY; MASS SCREENING; RADIATION DOSE; RADIATION INJURY; RADIOGRAPHY; RELATIVE BIOLOGIC EFFECTIVENESS; REVIEW; UNITED KINGDOM;

BREAST NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; FEMALE; GREAT BRITAIN; HUMANS; MAMMOGRAPHY; MASS SCREENING; NEOPLASMS, RADIATION-INDUCED; RADIATION DOSAGE; RELATIVE BIOLOGICAL EFFECTIVENESS;

EID: 69149102293     PISSN: 09524746     EISSN: 13616498     Source Type: Journal    
DOI: 10.1088/0952-4746/29/2A/S08     Document Type: Article

References (47)

1. Lloyd D C et al 1975 The relationship between chromosome aberrations and low LET radiation dose to human lymphocytes Int. J. Radiat. Biol. 28 75-90
2. Prosser J S et al 1983 The introduction of chromosome aberrations in human lymphocytes by exposure to tritiated water in vitro Radiat. Prot. Dosim. 4 21-6
3. Purrott R J, Reeder E J and Lovell S 1977 Chromosome aberration yields induced in human lymphocytes by 15 MeV electrons given at a conventional dose-rate and in microsecond pulses Int. J. Radiat. Biol. 31 251-6
4. Schmid E and Bauchinger M 1998 LET dependence of dicentric yields in human lymphocytes induced by low doses of sparsely ionizing radiations and its implication for risk assessments Health Phys. 74 719-21
5. Sasaki M S et al 1989 Induction of chromosome-aberrations in human-lymphocytes by monochromatic x-rays of quantum energy between 4.8 and 14.6 keV Int. J. Radiat. Biol. 56 975-88
6. Vral A, Thierens H and Deridder L 1992 Study of dose-rate and split-dose effects on the in vitro micronucleus yield in human lymphocytes exposed to x-rays Int. J. Radiat. Biol. 61 777-84
7. Thierens H, Vral A and Deridder L 1991 Biological dosimetry using the micronucleus assay for lymphocytes-interindividual differences in dose-response Health Phys. 61 623-30
8. Verhaegen F and Vral A 1994 Sensitivity of micronucleus induction in human-lymphocytes to low-LET radiation qualities-RBE and correlation of RBE and LET Radiat. Res. 139 208-13
9. Mill A J et al 1996 Micronucleus induction in human lymphocytes: comparative effects of x rays, alpha particles, beta particles and neutrons and implications for biological dosimetry Radiat. Res. 145 575-85
10. Hugtenburg R 2008 Cumulative differential dose as a function of LET for 3 sources: Hiroshima, 250 kVp x-rays and 28 kVp x-rays (personal communication)
11. Pattison J E et al 2001 Experimental simulation of A-bomb gamma ray spectra for radiobiology studies Radiat. Prot. Dosim. 95 125-36
12. Heyes G J and Mill A J 2004 The neoplastic transformation potential of mammography x rays and atomic bomb spectrum radiation Radiat. Res. 162 120-7
13. Mendonca M S et al 1995 Loss of a putative tumor suppressor locus after gamma-ray-induced neoplastic transformation of HeLa x skin fibroblast human cell hybrids Radiat. Res. 143 34-44
14. Frankenberg D et al 2002 Enhanced neoplastic transformation by mammography x rays relative to 200 kVp x rays: indication for a strong dependence on photon energy of the RBEM for various end points Radiat. Res. 157 99-105
15. Goggelmann W et al 2003 Re-evaluation of the RBE of 29 kV x-rays (mammography x-rays) relative to 220 kV x-rays using neoplastic transformation of human CGL1-hybrid cells Radiat. Environ. Biophys. 42 175-82
16. Preston D L et al 2002 Radiation effects on breast cancer risk: a pooled analysis of eight cohorts Radiat. Res. 158 220-35
17. Heyes G J, Mill A J and Charles M W 2006 Enhanced biological effectiveness of low energy x-rays and implications for the UK breast screening programme Br. J. Radiol. 79 195-200
18. Frankenberg D et al 2002 Mutation induction and neoplastic transformation in human and human-hamster hybrid cells: dependence on photon energy and modulation in the low dose range J. Radiol. Prot. 22 A17-20
19. Preston D L et al 2004 Effect of recent changes in atomic bomb survivor dosimetry on cancer mortality risk estimates Radiat. Res. 162 377-89
20. Law J, Faulkner K and Young K C 2007 Risk factors for induction of breast cancer by x-rays and their implications for breast screening Br. J. Radiol. 80 261-6
21. Young K C et al 2003 Review of Radiation Risk in Breast Screening: Report by a joint working party of the NHSBSP National Coordinating Group for Physics Quality Assurance and the National Radiological Protection Board (Sheffield: National Health Service Cancer Screening Programme)
22. Law J and Faulkner K 2001 Cancers detected and induced, and associated risk and benefit, in a breast screening programme Br. J. Radiol. 74 1121-7
23. Berrington de Gonzalez A and Darby S 2004 Risk of cancer from diagnostic x-rays: estimates for the UK and 14 other countries Lancet 363 345-51
24. Upton A C 2003 The state of the art in the 1990's: NCRP Report No. 136 on the scientific bases for linearity in the dose-response relationship for ionizing radiation Health Phys. 85 15-22
25. Berrington de Gonzalez A and Reeves G 2005 Mammographic screening before age 50 years in the UK: comparison of the radiation risks with the mortality benefits Br. J. Cancer 93 590-6
26. Azzam E I et al 1996 Low-dose ionizing radiation decreases the frequency of neoplastic transformation to a level below the spontaneous rate in C3H 10T1/2 cells Radiat. Res. 146 369-73
27. Elmore E et al 2005 Neoplastic transformation in vitro induced by low doses of 232 MeV protons Int. J. Radiat. Biol. 81 291-7
28. Hooker A M et al 2004 The linear no-threshold model does not hold for low-dose ionizing radiation Radiat. Res. 162 447-52
29. Ko S J et al 2004 Neoplastic transformation in vitro after exposure to low doses of mammographic-energy x rays: quantitative and mechanistic aspects Radiat. Res. 162 646-54
30. Portess D I et al 2007 Low-dose irradiation of nontransformed cells stimulates the selective removal of precancerous cells via intercellular induction of apoptosis Cancer Res. 67 1246-53
31. Redpath J L 2006 Health risks of low photon energy imaging Radiat. Prot. Dosim. 122 528-33
32. Redpath J L and Antoniono R J 1998 Induction of an adaptive response against spontaneous neoplastic transformation in vitro by low-dose gamma radiation Radiat. Res. 149 517-20
33. Redpath J L et al 2001 The shape of the dose-response curve for radiation-induced neoplastic transformation in vitro: evidence for an adaptive response against neoplastic transformation at low doses of low-LET radiation Radiat. Res. 156 700-7
34. Redpath J L et al 2003 Low doses of diagnostic energy x-rays protect against neoplastic transformation in vitro Int. J. Radiat. Biol. 79 235-40
35. Bettega B et al 1997 Alpha-particle-induced neoplastic transformation in synchronized hybrid cells of HeLa and human skin fibroblasts Int. J. Radiat. Biol. 72 523-9
36. Lewis D A et al 2001 Production of delayed death and neoplastic transformation in CGL1 cells by radiation-induced bystander effects Radiat. Res. 156 251-8
37. Mendonca M S et al 2000 Loss of chromosome 14 increases the radiosensitivity of CGL1 human hybrid cells but lowers their susceptibility to radiation induced neoplastic transformation Mutagenesis 15 187-93
38. Heyes G J, Mill A J and Charles M W 2006 Enhanced biological effectiveness of low energy x-rays and implications for the UK breast screening programme-reply Br. J. Radiol. 79 855-7
39. Elmore E et al 2006 The effect of dose rate on radiation-induced neoplastic transformation in vitro by low doses of low-LET radiation Radiat. Res. 166 832-8
40. Ronckers C M et al 2008 Multiple diagnostic x-rays for spine deformities and risk of breast cancer Cancer Epidemiol. Biomark. Prevent. 17 605-13
41. Ma H Y et al 2008 Low-dose medical radiation exposure and breast cancer risk in women under age 50years overall and by estrogen and progesterone receptor status: results from a case-control and a case-case comparison Breast Cancer Res. Treat. 109 77-90
42. Rothkamm K and Lobrich M 2003 Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses Proc. Natl Acad. Sci. USA 100 5057-62
43. Millikan R C et al 2005 Polymorphisms in DNA repair genes, medical exposure to ionizing radiation, and breast cancer risk Cancer Epidemiol. Biomark. Prevent. 14 2326-34
44. Brenner D J and Sachs R K 2006 Estimating radiation-induced cancer risks at very low doses: rationale for using a linear no-threshold approach Radiat. Environ. Biophys. 44 253-6
45. ICRP 2007 Publication 103. The 2007 Recommendations of the International Commission on Radiological Protection ed J Valentin
46. Goffin J et al 2001 Re: Magnetic resonance imaging and mammography in women with a hereditary risk of breast cancer J. Natl Cancer Inst. 93 1754
47. NICE 2006 Familial breast cancer: the classification and care of women at risk of familial breast cancer in primary, secondary and tertiary care. Update NICE Clinical Guideline 41. National Collaborating Centre for Primary Care