메뉴 건너뛰기




Volumn 106, Issue 31, 2009, Pages 12944-12949

Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia

Author keywords

Candidate gene resequencing; Copy number alterations; Loss of heterozygosity (LOH); Microarray; Single nucleotide polymorphism (SNP)

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE LYMPHOBLASTIC LEUKEMIA; ARTICLE; CHILD; CHILDHOOD CANCER; COHORT ANALYSIS; GENE SEQUENCE; GENETIC ANALYSIS; GENOME; HUMAN; MAJOR CLINICAL STUDY; MUTATIONAL ANALYSIS; OBSERVATION; POINT MUTATION; PRIORITY JOURNAL; RECURRENT DISEASE; SINGLE NUCLEOTIDE POLYMORPHISM; TUMOR GENE; FEMALE; GENE DOSAGE; GENE TRANSLOCATION; GENETICS; HETEROZYGOSITY LOSS; MALE; MUTATION;

EID: 69149083958     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903142106     Document Type: Article
Times cited : (154)

References (41)
  • 3
    • 33750720307 scopus 로고    scopus 로고
    • Induction of apoptosis in lymphoid and myeloid leukemia
    • Schimmer AD (2006) Induction of apoptosis in lymphoid and myeloid leukemia. Curr Oncol Rep 8:430-436.
    • (2006) Curr Oncol Rep , vol.8 , pp. 430-436
    • Schimmer, A.D.1
  • 4
    • 34147224008 scopus 로고    scopus 로고
    • Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia
    • Mullighan CG, et al. (2007) Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature 446:758-764.
    • (2007) Nature , vol.446 , pp. 758-764
    • Mullighan, C.G.1
  • 5
    • 43049139905 scopus 로고    scopus 로고
    • BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
    • Mullighan CG, et al. (2008) BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature 453:110-114.
    • (2008) Nature , vol.453 , pp. 110-114
    • Mullighan, C.G.1
  • 6
    • 57749114621 scopus 로고    scopus 로고
    • 250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies
    • Dunbar AJ, et al. (2008) 250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies. Cancer Res 68:10349-10357.
    • (2008) Cancer Res , vol.68 , pp. 10349-10357
    • Dunbar, A.J.1
  • 7
    • 38949123096 scopus 로고    scopus 로고
    • Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML
    • Gondek LP, et al. (2008) Chromosomal lesions and uniparental disomy detected by SNP arrays in MDS, MDS/MPD, and MDS-derived AML. Blood 111:1534-1542.
    • (2008) Blood , vol.111 , pp. 1534-1542
    • Gondek, L.P.1
  • 8
    • 12544257171 scopus 로고    scopus 로고
    • Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias
    • Raghavan M, et al. (2005) Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias. Cancer Res 65:375-378.
    • (2005) Cancer Res , vol.65 , pp. 375-378
    • Raghavan, M.1
  • 9
    • 33748450145 scopus 로고    scopus 로고
    • Disclosure of candidate genes in acute myeloid leukemia with complex karyotypes using microarray-based molecular characterization
    • Rucker FG, et al. (2006) Disclosure of candidate genes in acute myeloid leukemia with complex karyotypes using microarray-based molecular characterization. J Clin Oncol 24:3887-3894.
    • (2006) J Clin Oncol , vol.24 , pp. 3887-3894
    • Rucker, F.G.1
  • 10
    • 28544450726 scopus 로고    scopus 로고
    • Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): A review of four consecutive childhood AML trials conducted between 1981 and 2000
    • Ravindranath Y, et al. (2005) Pediatric Oncology Group (POG) studies of acute myeloid leukemia (AML): A review of four consecutive childhood AML trials conducted between 1981 and 2000. Leukemia 19:2101-2116.
    • (2005) Leukemia , vol.19 , pp. 2101-2116
    • Ravindranath, Y.1
  • 11
    • 28544434779 scopus 로고    scopus 로고
    • Successive clinical trials for childhood acute myeloid leukemia at St Jude Children's Research Hospital, from 1980 to 2000
    • Ribeiro RC, et al. (2005) Successive clinical trials for childhood acute myeloid leukemia at St Jude Children's Research Hospital, from 1980 to 2000. Leukemia 19:2125-2129.
    • (2005) Leukemia , vol.19 , pp. 2125-2129
    • Ribeiro, R.C.1
  • 12
    • 33846320508 scopus 로고    scopus 로고
    • Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia
    • Rubnitz JE, et al. (2007) Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia. Cancer 109:157-163.
    • (2007) Cancer , vol.109 , pp. 157-163
    • Rubnitz, J.E.1
  • 13
    • 33646575624 scopus 로고    scopus 로고
    • Implications of NRAS mutations in AML: A study of 2502 patients
    • Bacher U, Haferlach T, Schoch C, Kern W, Schnittger S (2006) Implications of NRAS mutations in AML: A study of 2502 patients. Blood 107:3847-3853.
    • (2006) Blood , vol.107 , pp. 3847-3853
    • Bacher, U.1    Haferlach, T.2    Schoch, C.3    Kern, W.4    Schnittger, S.5
  • 14
    • 1442356729 scopus 로고    scopus 로고
    • CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: Prognostic relevance and analysis of cooperating mutations
    • Frohling S, et al. (2004) CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: Prognostic relevance and analysis of cooperating mutations. J Clin Oncol 22:624-633.
    • (2004) J Clin Oncol , vol.22 , pp. 624-633
    • Frohling, S.1
  • 15
    • 8844272599 scopus 로고    scopus 로고
    • PTPN11 mutations in pediatric patients with acute myeloid leukemia: Results from the Children's Cancer Group
    • Loh ML, et al. (2004) PTPN11 mutations in pediatric patients with acute myeloid leukemia: Results from the Children's Cancer Group. Leukemia 18:1831-1834.
    • (2004) Leukemia , vol.18 , pp. 1831-1834
    • Loh, M.L.1
  • 16
    • 44049086446 scopus 로고    scopus 로고
    • Cooperating gene mutations in acute myeloid leukemia: A review of the literature
    • Renneville A, et al. (2008) Cooperating gene mutations in acute myeloid leukemia: A review of the literature. Leukemia 22:915-931.
    • (2008) Leukemia , vol.22 , pp. 915-931
    • Renneville, A.1
  • 17
    • 0141482006 scopus 로고    scopus 로고
    • FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: Prognostic significance and relation to cellular drug resistance
    • Zwaan CM, et al. (2003) FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: Prognostic significance and relation to cellular drug resistance. Blood 102:2387-2394.
    • (2003) Blood , vol.102 , pp. 2387-2394
    • Zwaan, C.M.1
  • 18
    • 38049100456 scopus 로고    scopus 로고
    • Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma
    • BeroukhimR, et al. (2007) Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma. Proc Natl Acad Sci USA 104:20007-20012.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20007-20012
    • BeroukhimR1
  • 19
    • 1542515338 scopus 로고    scopus 로고
    • A census of human cancer genes
    • Futreal PA, et al. (2004) A census of human cancer genes. Nat Rev Cancer 4:177-183.
    • (2004) Nat Rev Cancer , vol.4 , pp. 177-183
    • Futreal, P.A.1
  • 20
    • 33745522117 scopus 로고    scopus 로고
    • Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM
    • Yin W, Rossin A, Clifford JL, Gronemeyer H (2006) Co-resistance to retinoic acid and TRAIL by insertion mutagenesis into RAM. Oncogene 25:3735-3744.
    • (2006) Oncogene , vol.25 , pp. 3735-3744
    • Yin, W.1    Rossin, A.2    Clifford, J.L.3    Gronemeyer, H.4
  • 21
    • 40649110240 scopus 로고    scopus 로고
    • Genes encoded within 8q24 on the amplicon of a large extrachromosomal element are selectively repressed during the terminal differentiation of HL-60 cells
    • Hirano T, et al. (2008) Genes encoded within 8q24 on the amplicon of a large extrachromosomal element are selectively repressed during the terminal differentiation of HL-60 cells. Mutat Res 640:97-106.
    • (2008) Mutat Res , vol.640 , pp. 97-106
    • Hirano, T.1
  • 22
    • 62249133709 scopus 로고    scopus 로고
    • Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
    • Guttman M,et al. (2009) Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. Nature 458:223-227.
    • (2009) Nature , vol.458 , pp. 223-227
    • Guttman, M.1
  • 23
    • 35348873113 scopus 로고    scopus 로고
    • Mutations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Raine syndrome), highlighting a crucial molecule in bone development
    • Simpson MA, et al. (2007) Mutations in FAM20C are associated with lethal osteosclerotic bone dysplasia (Raine syndrome), highlighting a crucial molecule in bone development. Am J Hum Genet 81:906-912.
    • (2007) Am J Hum Genet , vol.81 , pp. 906-912
    • Simpson, M.A.1
  • 24
    • 4444354353 scopus 로고    scopus 로고
    • Identifying novel homozygous deletions by microsatellite analysis and characterization of tumor suppressor candidate 1 gene, TUSC1, on chromosome 9p in human lung cancer
    • Shan Z, Parker T, Wiest JS (2004) Identifying novel homozygous deletions by microsatellite analysis and characterization of tumor suppressor candidate 1 gene, TUSC1, on chromosome 9p in human lung cancer. Oncogene 23:6612-6620.
    • (2004) Oncogene , vol.23 , pp. 6612-6620
    • Shan, Z.1    Parker, T.2    Wiest, J.S.3
  • 25
    • 0034661112 scopus 로고    scopus 로고
    • BCoR, a novel corepressor involved in BCL-6 repression
    • Huynh KD, Fischle W, Verdin E, Bardwell VJ (2000) BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev 14:1810-1823.
    • (2000) Genes Dev , vol.14 , pp. 1810-1823
    • Huynh, K.D.1    Fischle, W.2    Verdin, E.3    Bardwell, V.J.4
  • 26
    • 37349081408 scopus 로고    scopus 로고
    • ATP-dependent transport of leukotrienes B4 and C4 by the multidrug resistance protein ABCC4 (MRP4)
    • Rius M, Hummel-Eisenbeiss J, Keppler D (2008) ATP-dependent transport of leukotrienes B4 and C4 by the multidrug resistance protein ABCC4 (MRP4). J Pharmacol Exp Ther 324:86-94.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 86-94
    • Rius, M.1    Hummel-Eisenbeiss, J.2    Keppler, D.3
  • 27
    • 0029838317 scopus 로고    scopus 로고
    • Fusion of the MLL gene with two different genes, AF-6 and AF-5alpha, by a complex translocation involving chromosomes 5, 6, 8 and 11 in infant leukemia
    • Taki T, et al. (1996) Fusion of the MLL gene with two different genes, AF-6 and AF-5alpha, by a complex translocation involving chromosomes 5, 6, 8 and 11 in infant leukemia. Oncogene 13:2121-2130.
    • (1996) Oncogene , vol.13 , pp. 2121-2130
    • Taki, T.1
  • 28
    • 3042722089 scopus 로고    scopus 로고
    • PRDM5 is silenced in human cancers and has growth suppressive activities
    • Deng Q, Huang S (2004) PRDM5 is silenced in human cancers and has growth suppressive activities. Oncogene 23:4903-4910.
    • (2004) Oncogene , vol.23 , pp. 4903-4910
    • Deng, Q.1    Huang, S.2
  • 29
    • 33747873409 scopus 로고    scopus 로고
    • Chromatin structural elements and chromosomal translocations in leukemia
    • Zhang Y, Rowley JD (2006) Chromatin structural elements and chromosomal translocations in leukemia. DNA Repair (Amst) 5:1282-1297.
    • (2006) DNA Repair (Amst) , vol.5 , pp. 1282-1297
    • Zhang, Y.1    Rowley, J.D.2
  • 30
    • 44449151696 scopus 로고    scopus 로고
    • Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia
    • Gupta M, et al. (2008) Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia. Genes Chromosomes Cancer 47:729-739.
    • (2008) Genes Chromosomes Cancer , vol.47 , pp. 729-739
    • Gupta, M.1
  • 31
    • 46749114860 scopus 로고    scopus 로고
    • Uniparental disomy may be associated with microsatellite instability in acute myeloid leukemia (AML) with a normal karyotype
    • Serrano E, et al. (2008) Uniparental disomy may be associated with microsatellite instability in acute myeloid leukemia (AML) with a normal karyotype. Leuk Lymphoma 49:1178-1183.
    • (2008) Leuk Lymphoma , vol.49 , pp. 1178-1183
    • Serrano, E.1
  • 32
    • 33646911907 scopus 로고    scopus 로고
    • Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays
    • Beroukhim R, et al. (2006) Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays. PLoS Comput Biol 2:e41.
    • (2006) PLoS Comput Biol , vol.2
    • Beroukhim, R.1
  • 33
    • 23744498520 scopus 로고    scopus 로고
    • Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22)
    • Nanri T, et al. (2005) Mutations in the receptor tyrosine kinase pathway are associated with clinical outcome in patients with acute myeloblastic leukemia harboring t(8;21)(q22;q22). Leukemia 19:1361-1366.
    • (2005) Leukemia , vol.19 , pp. 1361-1366
    • Nanri, T.1
  • 34
    • 37249015529 scopus 로고    scopus 로고
    • Familial myelodysplasia and acute myeloid leukaemia: A review
    • Owen C, Barnett M, Fitzgibbon J (2008) Familial myelodysplasia and acute myeloid leukaemia: A review. Br J Haematol 140:123-132.
    • (2008) Br J Haematol , vol.140 , pp. 123-132
    • Owen, C.1    Barnett, M.2    Fitzgibbon, J.3
  • 35
    • 36248980204 scopus 로고    scopus 로고
    • Characterizing the cancer genome in lung adenocarcinoma
    • Weir BA, et al. (2007) Characterizing the cancer genome in lung adenocarcinoma. Nature 450:893-898.
    • (2007) Nature , vol.450 , pp. 893-898
    • Weir, B.A.1
  • 36
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • Jones S, et al. (2008) Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321:1801-1806.
    • (2008) Science , vol.321 , pp. 1801-1806
    • Jones, S.1
  • 37
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Anonymous
    • Anonymous (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 455:1061-1068.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 38
    • 52949127312 scopus 로고    scopus 로고
    • An integrated genomic analysis of human glioblastoma multiforme
    • Parsons DW, et al. (2008) An integrated genomic analysis of human glioblastoma multiforme. Science 321:1807-1812.
    • (2008) Science , vol.321 , pp. 1807-1812
    • Parsons, D.W.1
  • 39
    • 55849099654 scopus 로고    scopus 로고
    • Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers
    • Leary RJ, et al. (2008) Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. Proc Natl Acad Sci USA 105:16224-16229.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 16224-16229
    • Leary, R.J.1
  • 40
    • 33749993417 scopus 로고    scopus 로고
    • The consensus coding sequences of human breast and colorectal cancers
    • Sjoblom T, et al. (2006) The consensus coding sequences of human breast and colorectal cancers. Science 314:268-274.
    • (2006) Science , vol.314 , pp. 268-274
    • Sjoblom, T.1
  • 41
    • 55549101623 scopus 로고    scopus 로고
    • DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
    • Ley TJ, et al. (2008) DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome. Nature 456:66-72.
    • (2008) Nature , vol.456 , pp. 66-72
    • Ley, T.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.