메뉴 건너뛰기




Volumn 55, Issue 8, 2009, Pages 1409-1422

Application-specific R&D capabilities and the advantage of incumbents: Evidence from the anticancer drug market

Author keywords

Competence destruction; Incumbent; Market specificity; R D; Technological change

Indexed keywords

ANTICANCER DRUG; APPLICATION-SPECIFIC; BIOTECHNOLOGY REVOLUTION; COMPETENCE DESTRUCTION; COMPETITIVE ADVANTAGE; COMPLEMENTARY ASSETS; DRUG DISCOVERY; IN-PHASE; INCUMBENT; MARKET LEADERSHIP; MARKET SPECIFICITY; NEW TECHNOLOGIES; RESEARCH AND DEVELOPMENT; STRATEGIC FACTORS; TECHNOLOGICAL CHANGE; TECHNOLOGICAL DISCONTINUITIES; TECHNOLOGICAL PLATFORM;

EID: 69049120449     PISSN: 00251909     EISSN: 15265501     Source Type: Journal    
DOI: 10.1287/mnsc.1090.1027     Document Type: Article
Times cited : (52)

References (54)
  • 1
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society, Accessed March 10, 2008
    • References American Cancer Society. 2000. Cancer facts & figures. Accessed March 10, 2008, http://www.cancer.org/downloads/STT/F&F00.pdf.
    • (2000) Cancer Facts & Figures
  • 2
    • 84989092230 scopus 로고
    • Strategic assets and organizational rent
    • Amit, R., P. J. H. Schoemaker. 1993. Strategic assets and organizational rent. Strategic Management J. 14(1) 33-46.
    • (1993) Strategic Management J. , vol.14 , Issue.1 , pp. 33-46
    • Amit, R.1    Schoemaker, P.J.H.2
  • 4
    • 16244379817 scopus 로고    scopus 로고
    • Capturing knowledge within and across firm boundaries: Evidence from clinical development
    • Azoulay, P. 2004. Capturing knowledge within and across firm boundaries: Evidence from clinical development. Amer. Econom. Rev. 94(5) 1591-1612.
    • (2004) Amer. Econom. Rev. , vol.94 , Issue.5 , pp. 1591-1612
    • Azoulay, P.1
  • 5
    • 84896930624 scopus 로고
    • Firm resources and sustained competitive advantage
    • Barney, J. B. 1991. Firm resources and sustained competitive advantage. J. Management 17(1) 99-120.
    • (1991) J. Management , vol.17 , Issue.1 , pp. 99-120
    • Barney, J.B.1
  • 8
    • 0030360190 scopus 로고    scopus 로고
    • The Fates of de novo and de alio producers in the american automobile industry 1885-1981
    • Carroll, G. R., L. S. Bigelow, M. D. L. Seidel, L. B. Tsai. 1996. The Fates of de novo and de alio producers in the american automobile industry 1885-1981. Strategic Management J. 17(Special Issue) 117-137.
    • (1996) Strategic Management J. , vol.17 , Issue.SPECL. ISSUE , pp. 117-137
    • Carroll, G.R.1    Bigelow, L.S.2    Seidel, M.D.L.3    Tsai, L.B.4
  • 9
    • 11144242211 scopus 로고    scopus 로고
    • Timeline: Chemotherapy and the war on cancer
    • Chabner, B. A., T. G. Roberts, Jr. 2005. Timeline: Chemotherapy and the war on cancer. Nature Rev. Cancer 5 65-72.
    • (2005) Nature Rev. Cancer , vol.5 , pp. 65-72
    • Chabner, B.A.1    Roberts Jr., T.G.2
  • 10
    • 0003412801 scopus 로고    scopus 로고
    • Harvard Business School Press, Boston
    • Christensen, C. 1997. The Innovator's Dilemma. Harvard Business School Press, Boston.
    • (1997) Innovator's Dilemma
    • Christensen, C.1
  • 11
    • 84989052060 scopus 로고
    • Strategies for product cannibalism
    • Conner, K. R. 1988. Strategies for product cannibalism. Strategic Management J. 9(Special Issue) 9-26.
    • (1988) Strategic Management J. , vol.9 , Issue.SPECL. ISSUE , pp. 9-26
    • Conner, K.R.1
  • 12
    • 0002354935 scopus 로고
    • Strategic responses to technological threats
    • Cooper, A. C., D. Schendel. 1976. Strategic responses to technological threats. Bus. Horizons 19(1) 61-69.
    • (1976) Bus. Horizons , vol.19 , Issue.1 , pp. 61-69
    • Cooper, A.C.1    Schendel, D.2
  • 13
    • 0000857363 scopus 로고
    • Assets accumulation and sustainability of competition advantage
    • Dierickx, I., K. Cool. 1989. Assets accumulation and sustainability of competition advantage. Management Sci. 35(12) 1504-1514.
    • (1989) Management Sci. , vol.35 , Issue.12 , pp. 1504-1514
    • Dierickx, I.1    Cool, K.2
  • 14
  • 15
    • 34249314179 scopus 로고    scopus 로고
    • Organizational scope and investment: Evidence from the drug development strategies and performance of biopharmaceutical firms
    • National Bureau of Economic Research, Cambrige, MA
    • Guedj, I., D. Scharfstein. 2004. Organizational scope and investment: Evidence from the drug development strategies and performance of biopharmaceutical firms. NBER Working Paper 10933, National Bureau of Economic Research, Cambrige, MA.
    • (2004) NBER Working Paper 10933
    • Guedj, I.1    Scharfstein, D.2
  • 16
    • 0000721385 scopus 로고    scopus 로고
    • Know-how and asset complementarity and dynamic capability accumulation: The case of R&D
    • Helfat, C. E. 1997. Know-how and asset complementarity and dynamic capability accumulation: The case of R&D. Strategic Management J. 18(5) 339-360.
    • (1997) Strategic Management J. , vol.18 , Issue.5 , pp. 339-360
    • Helfat, C.E.1
  • 17
    • 84869431550 scopus 로고
    • Underinvestment and incompetence as responses to radical innovation-Evidence from the photolithographic alignment equipment industry
    • Henderson, R. M. 1993. Underinvestment and incompetence as responses to radical innovation-Evidence from the photolithographic alignment equipment industry. RAND J. Econom. 24(2) 248-270.
    • (1993) RAND J. Econom. , vol.24 , Issue.2 , pp. 248-270
    • Henderson, R.M.1
  • 18
    • 0000581477 scopus 로고
    • Of life-cycles real and imaginary-The unexpectedly long old-age of optical lithography
    • Henderson, R. M. 1995. Of life-cycles real and imaginary-The unexpectedly long old-age of optical lithography. Res. Policy 24(4) 631-643.
    • (1995) Res. Policy , vol.24 , Issue.4 , pp. 631-643
    • Henderson, R.M.1
  • 19
    • 0001511053 scopus 로고
    • Architectural innovation: The reconfiguration of existing product technologies and the failure of established firms
    • Henderson, R. M., K. B. Clark. 1990. Architectural innovation: The reconfiguration of existing product technologies and the failure of established firms. Admin. Sci. Quart. 35(1) 9-30.
    • (1990) Admin. Sci. Quart. , vol.35 , Issue.1 , pp. 9-30
    • Henderson, R.M.1    Clark, K.B.2
  • 20
    • 0000084779 scopus 로고    scopus 로고
    • The pharmaceutical industry and the revolution in molecular biology: Interactions among scientific, institutional, and organizational change
    • D. C. Mowery, R. R. Nelson, eds., Cambridge University Press, Cambridge, UK
    • Henderson, R. M., L. Orsenigo, G. Pisano. 1999. The pharmaceutical industry and the revolution in molecular biology: Interactions among scientific, institutional, and organizational change. D. C. Mowery, R. R. Nelson, eds. Sources of Industrial Leadership. Cambridge University Press, Cambridge, UK, 267-311.
    • (1999) Sources of Industrial Leadership , pp. 267-311
    • Henderson, R.M.1    Orsenigo, L.2    Pisano, G.3
  • 21
    • 69049092700 scopus 로고    scopus 로고
    • Accessed November 4
    • International Business Machines (IBM). History of IBM. Accessed November 4, 2005, http://www-03.ibm.com/ibm/history/history/history-intro.html.
    • (2005) History of IBM
  • 22
    • 0000736534 scopus 로고    scopus 로고
    • Dominance by birthright: Entry of prior radio producers and competitive ramifications in the US television receiver industry
    • Klepper, S., K. L. Simons. 2000. Dominance by birthright: Entry of prior radio producers and competitive ramifications in the US television receiver industry. Strategic Management J. 21(10/11) 997-1016.
    • (2000) Strategic Management J. , vol.21 , Issue.10-11 , pp. 997-1016
    • Klepper, S.1    Simons, K.L.2
  • 24
    • 0032395322 scopus 로고    scopus 로고
    • Strategic pricing of new pharmaceuticals
    • Lu, Z. J., W. S. Comanor. 1998. Strategic pricing of new pharmaceuticals. Rev. Econom. Statist. 80(1) 108-118.
    • (1998) Rev. Econom. Statist. , vol.80 , Issue.1 , pp. 108-118
    • Lu, Z.J.1    Comanor, W.S.2
  • 26
    • 0000359490 scopus 로고    scopus 로고
    • Toward a synthesis of the resource-based and dynamic-capability views of rent creation
    • Makadok, R. 2001. Toward a synthesis of the resource-based and dynamic-capability views of rent creation. Strategic Management J. 22 387-401.
    • (2001) Strategic Management J. , vol.22 , pp. 387-401
    • Makadok, R.1
  • 27
    • 0008529018 scopus 로고    scopus 로고
    • The underemphasized role of established firms as the sources of major innovations
    • Methe, D., A. Swaminathan, W. Mitchell. 1996. The underemphasized role of established firms as the sources of major innovations. Indust. Corporate Change 5(4) 1181-1203.
    • (1996) Indust. Corporate Change , vol.5 , Issue.4 , pp. 1181-1203
    • Methe, D.1    Swaminathan, A.2    Mitchell, W.3
  • 28
    • 84937303623 scopus 로고
    • The dynamics of evolving markets: The effects of business sales and age on dissolutions and divestitures
    • Mitchell, W. 1994. The dynamics of evolving markets: The effects of business sales and age on dissolutions and divestitures. Admin. Sci. Quart. 39(4) 575-602.
    • (1994) Admin. Sci. Quart. , vol.39 , Issue.4 , pp. 575-602
    • Mitchell, W.1
  • 30
    • 0000388296 scopus 로고
    • Diversification, ricardian rents, and tobin's Q
    • Montgomery, C. A., B. Wernerfelt. 1988. Diversification, ricardian rents, and Tobin's Q. RAND J. Econom. 19(4) 623-632.
    • (1988) RAND J. Econom. , vol.19 , Issue.4 , pp. 623-632
    • Montgomery, C.A.1    Wernerfelt, B.2
  • 31
    • 69049110958 scopus 로고    scopus 로고
    • Nature milestones: DNA technologies
    • Accessed April 24, 2009
    • Nature. 2007. Nature milestones: DNA technologies. Accessed April 24, 2009, http://www.nature.com/milestones/miledna/timeline.html.
    • (2007) Nature
  • 32
    • 69049118097 scopus 로고    scopus 로고
    • Nature milestones: Cancer
    • Accessed April 24, 2009
    • Nature Reviews Cancer. 2006. Nature milestones: Cancer. Accessed April 24, 2009, http://www.nature.com/milestones/milecancer/timeline.html.
    • (2006) Nature Reviews Cancer
  • 34
    • 21444437521 scopus 로고    scopus 로고
    • Econometric methods for fractional response variables with an application to 401(k) plan participation rates
    • Papke, L. E., J. Wooldridge. 1996. Econometric methods for fractional response variables with an application to 401(k) plan participation rates. J. Appl. Econometrics 11 619-632.
    • (1996) J. Appl. Econometrics , vol.11 , pp. 619-632
    • Papke, L.E.1    Wooldridge, J.2
  • 35
    • 37349015147 scopus 로고    scopus 로고
    • The drug discovery process: General principles and some case histories
    • H. P. Rang, ed., Churchill Livingstone, London
    • Rang, H. P. 2006. The drug discovery process: General principles and some case histories. H. P. Rang, ed. Drug Discovery and Development: Technology in Transition. Churchill Livingstone, London, 43-56.
    • (2006) Drug Discovery and Development: Technology in Transition , pp. 43-56
    • Rang, H.P.1
  • 37
    • 0000388376 scopus 로고    scopus 로고
    • Incumbent's advantage through exploiting complementary assets via interfirm cooperation
    • Rothaermel, F. T. 2001. Incumbent's advantage through exploiting complementary assets via interfirm cooperation. Strategic Management J. 22(6/7) 687-699.
    • (2001) Strategic Management J. , vol.22 , Issue.6-7 , pp. 687-699
    • Rothaermel, F.T.1
  • 38
    • 84989135219 scopus 로고
    • Diversification strategy and profitability
    • Rumelt, R. P. 1982. Diversification strategy and profitability. Strategic Management J. 3 359-369.
    • (1982) Strategic Management J. , vol.3 , pp. 359-369
    • Rumelt, R.P.1
  • 41
    • 34248358157 scopus 로고    scopus 로고
    • PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors
    • Shepart, C. R., J. Kassis, D. L. Whaley, H. G. Kim, A. Wells. 2007. PLC gamma contributes to metastasis of in situ-occurring mammary and prostate tumors. Oncogene 26(21) 3020-3026.
    • (2007) Oncogene , vol.26 , Issue.21 , pp. 3020-3026
    • Shepart, C.R.1    Kassis, J.2    Whaley, D.L.3    Kim, H.G.4    Wells, A.5
  • 42
    • 0007116216 scopus 로고    scopus 로고
    • Analyzing censored and sampleselected data with tobit and heckit models
    • Sigelman, L., L. Zeng. 1999. Analyzing censored and sampleselected data with tobit and heckit models. Political Anal. 8(2) 167-182.
    • (1999) Political Anal. , vol.8 , Issue.2 , pp. 167-182
    • Sigelman, L.1    Zeng, L.2
  • 43
    • 0033283301 scopus 로고    scopus 로고
    • Technological resources and the direction of corporate diversification: Toward an integration of the resource-based view and transaction cost economics
    • Silverman, B. S. 1999. Technological resources and the direction of corporate diversification: Toward an integration of the resource-based view and transaction cost economics. Management Sci. 45(8) 1109-1124.
    • (1999) Management Sci. , vol.45 , Issue.8 , pp. 1109-1124
    • Silverman, B.S.1
  • 46
    • 38549086633 scopus 로고
    • Profiting from technological innovation: Implications for integration, collaboration, licensing and public policy
    • Teece, D. J. 1986. Profiting from technological innovation: Implications for integration, collaboration, licensing and public policy. Res. Policy 15 285-305.
    • (1986) Res. Policy , vol.15 , pp. 285-305
    • Teece, D.J.1
  • 47
    • 0342775775 scopus 로고    scopus 로고
    • Dynamic capabilities and strategic management
    • Teece, D. J., G. Pisano, A. Shuen. 1997. Dynamic capabilities and strategic management. Strategic Management J. 18(7) 509-533.
    • (1997) Strategic Management J. , vol.18 , Issue.7 , pp. 509-533
    • Teece, D.J.1    Pisano, G.2    Shuen, A.3
  • 48
    • 0000623840 scopus 로고    scopus 로고
    • Unraveling the process of creative destruction: Complementary assets and incumbent survival in the typesetter industry
    • Tripsas, M. 1997. Unraveling the process of creative destruction: Complementary assets and incumbent survival in the typesetter industry. Strategic Management J. 18 119-142.
    • (1997) Strategic Management J. , vol.18 , pp. 119-142
    • Tripsas, M.1
  • 49
    • 84881946969 scopus 로고
    • Technological discontinuities and organizational environments
    • Tushman, M., P. Anderson. 1986. Technological discontinuities and organizational environments. Admin. Sci. Quart. 31(3) 439-465.
    • (1986) Admin. Sci. Quart. , vol.31 , Issue.3 , pp. 439-465
    • Tushman, M.1    Anderson, P.2
  • 53
    • 0141792319 scopus 로고    scopus 로고
    • Understanding dynamic capabilities
    • Winter, S. G. 2003. Understanding dynamic capabilities. Strategic Management J. 24 991-995.
    • (2003) Strategic Management J. , vol.24 , pp. 991-995
    • Winter, S.G.1
  • 54
    • 0018575022 scopus 로고
    • Historic milestones in curative chemotherapy
    • Zubrod, C. G. 1979. Historic milestones in curative chemotherapy. Seminars in Oncology 6(4) 490-505.
    • (1979) Seminars in Oncology , vol.6 , Issue.4 , pp. 490-505
    • Zubrod, C.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.