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Volumn , Issue , 2013, Pages 43-56

The drug discovery process: General principles and some case histories

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EID: 37349015147     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-7020-4299-7.00004-4     Document Type: Chapter
Times cited : (7)

References (12)
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    • Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug
    • Capdeville R, Buchdunger E, Zimmermann J, et al. Glivec (STI571, imatinib), a rationally developed, targeted anticancer drug. Nature Reviews Drug Discovery 2002, 1:493-502.
    • (2002) Nature Reviews Drug Discovery , vol.1 , pp. 493-502
    • Capdeville, R.1    Buchdunger, E.2    Zimmermann, J.3
  • 3
    • 0036527429 scopus 로고    scopus 로고
    • Protein kinases - the major drug targets of the twenty-first century?
    • Cohen P Protein kinases - the major drug targets of the twenty-first century?. Nature Reviews Drug Discovery 2002, 1:309-316.
    • (2002) Nature Reviews Drug Discovery , vol.1 , pp. 309-316
    • Cohen, P.1
  • 4
    • 0031595885 scopus 로고    scopus 로고
    • Paclitaxel (Taxol): a success story with valuable lessons for natural product drug discovery and development
    • Cragg GM Paclitaxel (Taxol): a success story with valuable lessons for natural product drug discovery and development. Medical Research Review 1998, 18:315-331.
    • (1998) Medical Research Review , vol.18 , pp. 315-331
    • Cragg, G.M.1
  • 5
    • 0034677966 scopus 로고    scopus 로고
    • Drug discovery: a historical perspective
    • Drews J Drug discovery: a historical perspective. Science 2000, 287:1960-1964.
    • (2000) Science , vol.287 , pp. 1960-1964
    • Drews, J.1
  • 6
    • 0033987746 scopus 로고    scopus 로고
    • Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelognous leukemia
    • Druker BJ, Lydon NB Lessons learned from the development of an Abl tyrosine kinase inhibitor for chronic myelognous leukemia. Journal of Clinical Investigation 2000, 105:3-7.
    • (2000) Journal of Clinical Investigation , vol.105 , pp. 3-7
    • Druker, B.J.1    Lydon, N.B.2
  • 7
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nature Medicine 1996, 2:561-566.
    • (1996) Nature Medicine , vol.2 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3
  • 8
    • 0035810147 scopus 로고    scopus 로고
    • Efficacy and safety of a specific inhibitor of the Bcr-Abl tyrosine kinase in chronic myeloid leukemia
    • Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the Bcr-Abl tyrosine kinase in chronic myeloid leukemia. New England Journal of Medicine 2001, 344:1031-1037.
    • (2001) New England Journal of Medicine , vol.344 , pp. 1031-1037
    • Druker, B.J.1    Talpaz, M.2    Resta, D.J.3
  • 9
    • 0030886937 scopus 로고    scopus 로고
    • Managing the drug discovery/development interface
    • Kennedy T Managing the drug discovery/development interface. Drug Discovery Today 1997, 2:436-444.
    • (1997) Drug Discovery Today , vol.2 , pp. 436-444
    • Kennedy, T.1
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  • 12
    • 0034665713 scopus 로고    scopus 로고
    • Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase
    • Schindler T, Bornmann W, Pellicana P, et al. Structural mechanism for STI-571 inhibition of Abelson tyrosine kinase. Science 2000, 289:1938-1942.
    • (2000) Science , vol.289 , pp. 1938-1942
    • Schindler, T.1    Bornmann, W.2    Pellicana, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.