-
1
-
-
0021928246
-
Intermediate filament and cross-linked envelope expression in human lung tumor cell lines
-
SP Banks-Schlegel AF Gazdar CC Harris 1985 Intermediate filament and cross-linked envelope expression in human lung tumor cell lines Cancer Res 45 1187 1197
-
(1985)
Cancer Res
, vol.45
, pp. 1187-1197
-
-
Banks-Schlegel, S.P.1
Gazdar, A.F.2
Harris, C.C.3
-
2
-
-
0025214710
-
Phorbol ester-induced cell cycle-specific growth inhibition of human B-lymphoma cell lines
-
M Beckwith DL Longo CD O'Connell et al. 1990 Phorbol ester-induced cell cycle-specific growth inhibition of human B-lymphoma cell lines J Natl Cancer Inst 82 501 509
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 501-509
-
-
Beckwith, M.1
Longo, D.L.2
O'Connell, C.D.3
-
4
-
-
34447251876
-
Chemotherapy-induced neuropathy
-
A Bhagra RD Rao 2007 Chemotherapy-induced neuropathy Curr Oncol Rep 9 290 299
-
(2007)
Curr Oncol Rep
, vol.9
, pp. 290-299
-
-
Bhagra, A.1
Rao, R.D.2
-
5
-
-
34249794861
-
Microtubule-associated proteins as targets in cancer chemotherapy
-
KMR Bhat V Setaluri 2007 Microtubule-associated proteins as targets in cancer chemotherapy Clin Cancer Res 13 2849 2854
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2849-2854
-
-
Bhat, K.M.R.1
Setaluri, V.2
-
6
-
-
38849159510
-
Pharmacokinetics in mice with xenografted tumors after intravenous administration of tasidotin (ILX651) or its carboxylate metabolite
-
PL Bonate D Beyerlein J Crawford et al. 2007 Pharmacokinetics in mice with xenografted tumors after intravenous administration of tasidotin (ILX651) or its carboxylate metabolite AAPS J 9 E378 E387
-
(2007)
AAPS J
, vol.9
-
-
Bonate, P.L.1
Beyerlein, D.2
Crawford, J.3
-
7
-
-
0038626993
-
Transplantable syngeneic rodent tumors
-
Teicher BA et al (eds) Humana Press, Totowa
-
Corbett TH, Polin L, Roberts BJ (2002) Transplantable syngeneic rodent tumors. In: Teicher BA et al (eds) Tumor models in cancer research. Humana Press, Totowa, pp 41-71
-
(2002)
Tumor Models in Cancer Research
, pp. 41-71
-
-
Corbett, T.H.1
Polin, L.2
Roberts, B.J.3
-
8
-
-
34147112848
-
Targeting the microtubules in breast cancer beyond taxanes: The epothilones
-
J Cortes J Baselga 2007 Targeting the microtubules in breast cancer beyond taxanes: the epothilones Oncologist 12 271 280
-
(2007)
Oncologist
, vol.12
, pp. 271-280
-
-
Cortes, J.1
Baselga, J.2
-
9
-
-
27744477635
-
Phase I and pharmacokinetic study of the dolastatin-15 analog tasidotin (ILX651) administered intravenously on days 1, 3 and 5 every 3 weeks in patients with advanced solid tumors
-
C Cunningham LJ Appleman M Kirvan-Visovatti et al. 2005 Phase I and pharmacokinetic study of the dolastatin-15 analog tasidotin (ILX651) administered intravenously on days 1, 3 and 5 every 3 weeks in patients with advanced solid tumors Clin Cancer Res 11 7825 7833
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7825-7833
-
-
Cunningham, C.1
Appleman, L.J.2
Kirvan-Visovatti, M.3
-
10
-
-
27744536541
-
A phase I study of the dolastatin-15 analog tasidotin (ILX651) administered intravenously daily for 5 consecutive days every 3 weeks in patients with advanced solid tumors
-
S Ebbinghaus E Rubin E Hersh et al. 2005 A phase I study of the dolastatin-15 analog tasidotin (ILX651) administered intravenously daily for 5 consecutive days every 3 weeks in patients with advanced solid tumors Clin Cancer Res 11 7807 7816
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7807-7816
-
-
Ebbinghaus, S.1
Rubin, E.2
Hersh, E.3
-
11
-
-
0031054593
-
Differential toxicity of camptothecin, topotecan and 9-aminocamptothecin to human, canine, and murine myeloid progenitors (CFU-GM) in vitro
-
C Erickson-Miller 1997 Differential toxicity of camptothecin, topotecan and 9-aminocamptothecin to human, canine, and murine myeloid progenitors (CFU-GM) in vitro Cancer Chemother Pharmacol 39 467 472
-
(1997)
Cancer Chemother Pharmacol
, vol.39
, pp. 467-472
-
-
Erickson-Miller, C.1
-
14
-
-
34848859978
-
Preclinical analysis of tasidotin HCl in Ewing's sarcoma, rhabdomyosarcoma, synovial sarcoma and osteosarcoma
-
V Garg W Zhang P Gidwani et al. 2007 Preclinical analysis of tasidotin HCl in Ewing's sarcoma, rhabdomyosarcoma, synovial sarcoma and osteosarcoma Clin Cancer Res 13 5446 5454
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5446-5454
-
-
Garg, V.1
Zhang, W.2
Gidwani, P.3
-
15
-
-
3042701597
-
Epothilones: Mechanism of action and biologic activity
-
S Goodin MP Kane EH Rubin 2004 Epothilones: mechanism of action and biologic activity J Clin Oncol 22 2015 2025
-
(2004)
J Clin Oncol
, vol.22
, pp. 2015-2025
-
-
Goodin, S.1
Kane, M.P.2
Rubin, E.H.3
-
16
-
-
31544467339
-
Evaluation of the antitumor efficacy, pharmacokinetics and pharmacodynamics of the histone deacetylase inhibitor depsipeptide in childhood cancer models in vivo
-
C Graham C Tucker J Creech et al. 2006 Evaluation of the antitumor efficacy, pharmacokinetics and pharmacodynamics of the histone deacetylase inhibitor depsipeptide in childhood cancer models in vivo Clin Cancer Res 12 223 234
-
(2006)
Clin Cancer Res
, vol.12
, pp. 223-234
-
-
Graham, C.1
Tucker, C.2
Creech, J.3
-
17
-
-
4143064717
-
Determination of vincristine in mouse plasma and brain tissues by liquid chromatography-electrospray mass spectrometry
-
P Guo X Wang F Zhou JM Gallo 2004 Determination of vincristine in mouse plasma and brain tissues by liquid chromatography-electrospray mass spectrometry J Chromatogr B 809 273 278
-
(2004)
J Chromatogr B
, vol.809
, pp. 273-278
-
-
Guo, P.1
Wang, X.2
Zhou, F.3
Gallo, J.M.4
-
18
-
-
34547515086
-
Nab-paclitaxel for breast cancer: A new formulation with an improved safety profile and greater efficacy
-
IC Henderson V Bhatia 2007 Nab-paclitaxel for breast cancer: a new formulation with an improved safety profile and greater efficacy Exp Rev Anticancer Ther 7 919 943
-
(2007)
Exp Rev Anticancer Ther
, vol.7
, pp. 919-943
-
-
Henderson, I.C.1
Bhatia, V.2
-
19
-
-
34247249906
-
Vascular disrupting agents in clinical development
-
P Hinnen FA Eskens 2007 Vascular disrupting agents in clinical development Brit J Cancer 96 1159 1165
-
(2007)
Brit J Cancer
, vol.96
, pp. 1159-1165
-
-
Hinnen, P.1
Eskens, F.A.2
-
21
-
-
47949117146
-
Effect of interleukin-2 pretreatment on paclitaxel absorption and tissue disposition after oral and intravenous administration in mice
-
B Hosten C Abbara B Petit et al. 2008 Effect of interleukin-2 pretreatment on paclitaxel absorption and tissue disposition after oral and intravenous administration in mice Drug Metab Dispos 36 1729 1735
-
(2008)
Drug Metab Dispos
, vol.36
, pp. 1729-1735
-
-
Hosten, B.1
Abbara, C.2
Petit, B.3
-
22
-
-
0027494879
-
Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients
-
MT Huizing ACF Keung H Rosing et al. 1993 Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients J Clin Oncol 11 2127 2135
-
(1993)
J Clin Oncol
, vol.11
, pp. 2127-2135
-
-
Huizing, M.T.1
Keung, A.C.F.2
Rosing, H.3
-
23
-
-
0000502679
-
The vinca alkaloids: A new class of oncolytic agents
-
IS Johnson JG Armstrong M Gorman et al. 1967 The vinca alkaloids: a new class of oncolytic agents Cancer Res 23 1390 1427
-
(1967)
Cancer Res
, vol.23
, pp. 1390-1427
-
-
Johnson, I.S.1
Armstrong, J.G.2
Gorman, M.3
-
24
-
-
0025824979
-
Mechanism of inhibition of cell proliferation by Vinca alkaloids
-
MA Jordan D Thrower L Wilson 1991 Mechanism of inhibition of cell proliferation by Vinca alkaloids Cancer Res 51 2212 2222
-
(1991)
Cancer Res
, vol.51
, pp. 2212-2222
-
-
Jordan, M.A.1
Thrower, D.2
Wilson, L.3
-
25
-
-
1942438028
-
Microtubules as a target for anticancer drugs
-
MA Jordan L Wilson 2004 Microtubules as a target for anticancer drugs Nat Rev Cancer 4 253 265
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 253-265
-
-
Jordan, M.A.1
Wilson, L.2
-
26
-
-
0018779369
-
Establishment and characterization of a human prostatic carcinoma cell line (PC-3)
-
ME Kaighn KS Narayan Y Ohnuki et al. 1979 Establishment and characterization of a human prostatic carcinoma cell line (PC-3) Investig Urol 17 16 23
-
(1979)
Investig Urol
, vol.17
, pp. 16-23
-
-
Kaighn, M.E.1
Narayan, K.S.2
Ohnuki, Y.3
-
28
-
-
0032031453
-
Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated vinca alkaloid
-
A Kruczynski JM Barret C Etievant et al. 1998 Antimitotic and tubulin-interacting properties of vinflunine, a novel fluorinated vinca alkaloid Biochem Pharmacol 55 635 648
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 635-648
-
-
Kruczynski, A.1
Barret, J.M.2
Etievant, C.3
-
29
-
-
0037033711
-
Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development
-
A Kruczynski C Etievant D Perrin et al. 2002 Characterization of cell death induced by vinflunine, the most recent Vinca alkaloid in clinical development Br J Cancer 86 143 150
-
(2002)
Br J Cancer
, vol.86
, pp. 143-150
-
-
Kruczynski, A.1
Etievant, C.2
Perrin, D.3
-
30
-
-
33746879918
-
Drug development in oncology: Classical cytotoxics and molecularly targeted agents
-
S Kummar M Gutierrez JH Doroshow et al. 2006 Drug development in oncology: classical cytotoxics and molecularly targeted agents Brit J Clin Pharmacol 62 15 26
-
(2006)
Brit J Clin Pharmacol
, vol.62
, pp. 15-26
-
-
Kummar, S.1
Gutierrez, M.2
Doroshow, J.H.3
-
31
-
-
55749097609
-
Bone marrow and tumor cell CFU and human tumor xenograft efficacy of non-camptothecin and camptothecin topoisomerase I inhibitors
-
LS Kurtzberg T Battle C Rouleau et al. 2008 Bone marrow and tumor cell CFU and human tumor xenograft efficacy of non-camptothecin and camptothecin topoisomerase I inhibitors Mol Cancer Ther 7 10 3212 3222
-
(2008)
Mol Cancer Ther
, vol.7
, Issue.10
, pp. 3212-3222
-
-
Kurtzberg, L.S.1
Battle, T.2
Rouleau, C.3
-
32
-
-
41549164459
-
The epothilones: Translating from the laboratory to the clinic
-
JJ Lee SM Swain 2008 The epothilones: translating from the laboratory to the clinic Clin Cancer Res 14 1618 1624
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1618-1624
-
-
Lee, J.J.1
Swain, S.M.2
-
33
-
-
40749125593
-
Taxanes in the management of gynecologic malignancies
-
M Markman 2008 Taxanes in the management of gynecologic malignancies Exp Rev Anticancer Ther 8 219 226
-
(2008)
Exp Rev Anticancer Ther
, vol.8
, pp. 219-226
-
-
Markman, M.1
-
34
-
-
5144226837
-
A predictive model of human myelotoxicity using five camptothecin derivatives and the in vitro colony-forming unit granulocyte/macrophage assay
-
N Masubuchi 2004 A predictive model of human myelotoxicity using five camptothecin derivatives and the in vitro colony-forming unit granulocyte/macrophage assay Clin Cancer Res 10 6722 6731
-
(2004)
Clin Cancer Res
, vol.10
, pp. 6722-6731
-
-
Masubuchi, N.1
-
35
-
-
0014115428
-
Production of free light chains of immunoglobulin by a haematopoietic cell line derived from a patient with multiple myeloma
-
Y Matsuoka GE Moore Y Yagi et al. 1967 Production of free light chains of immunoglobulin by a haematopoietic cell line derived from a patient with multiple myeloma Proc Soc Exp Biol Med 125 1246 1250
-
(1967)
Proc Soc Exp Biol Med
, vol.125
, pp. 1246-1250
-
-
Matsuoka, Y.1
Moore, G.E.2
Yagi, Y.3
-
37
-
-
33748991177
-
Phase I and pharmacokinetic study of tasidotin hydrochloride (ILX651), a third generation dolastatin-15 analog, administered weekly for 3 weeks every 28 days in patients with advanced solid tumors
-
AC Mita LA Hammond PL Bonate et al. 2006 Phase I and pharmacokinetic study of tasidotin hydrochloride (ILX651), a third generation dolastatin-15 analog, administered weekly for 3 weeks every 28 days in patients with advanced solid tumors Clin Cancer Res 12 5207 5215
-
(2006)
Clin Cancer Res
, vol.12
, pp. 5207-5215
-
-
Mita, A.C.1
Hammond, L.A.2
Bonate, P.L.3
-
38
-
-
3843053396
-
The binding mode of epothilone a on alpha, beta-tubulin by electron crystallography
-
JH Nettles H Li B Cornett 2004 The binding mode of epothilone A on alpha, beta-tubulin by electron crystallography Science 305 866 869
-
(2004)
Science
, vol.305
, pp. 866-869
-
-
Nettles, J.H.1
Li, H.2
Cornett, B.3
-
39
-
-
0034960408
-
Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine
-
VK Ngan K Bellman BT Hill et al. 2001 Mechanism of mitotic block and inhibition of cell proliferation by the semisynthetic Vinca alkaloids vinorelbine and its newer derivative vinflunine Mol Pharmacol 60 225 232
-
(2001)
Mol Pharmacol
, vol.60
, pp. 225-232
-
-
Ngan, V.K.1
Bellman, K.2
Hill, B.T.3
-
40
-
-
0034665163
-
Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules
-
VK Ngan K Bellman D Panda et al. 2000 Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules Cancer Res 60 5045 5051
-
(2000)
Cancer Res
, vol.60
, pp. 5045-5051
-
-
Ngan, V.K.1
Bellman, K.2
Panda, D.3
-
41
-
-
0019846038
-
Human tumor xenografts in athymic nude mice as a preclinical screen for anticancer agents
-
AA Ovejera DP Houchens 1981 Human tumor xenografts in athymic nude mice as a preclinical screen for anticancer agents Sem Oncol 8 386 393
-
(1981)
Sem Oncol
, vol.8
, pp. 386-393
-
-
Ovejera, A.A.1
Houchens, D.P.2
-
42
-
-
34447545904
-
Novel enhanced delivery taxanes: An update
-
Perez EA (2007) Novel enhanced delivery taxanes: an update. Semin Oncol 34:Suppl 1-5
-
(2007)
Semin Oncol
, vol.34
, Issue.SUPPL. 1-5
-
-
Perez, E.A.1
-
43
-
-
10744231168
-
Application of the CFU-GM assay to predict acute drug-induced neutropenia: An international blind trial to validate a prediction model for the maximum tolerated dose (MTD) of myelosuppressive xenobiotics
-
A Pessina 2003 Application of the CFU-GM assay to predict acute drug-induced neutropenia: an international blind trial to validate a prediction model for the maximum tolerated dose (MTD) of myelosuppressive xenobiotics Toxicol Sci 75 355 367
-
(2003)
Toxicol Sci
, vol.75
, pp. 355-367
-
-
Pessina, A.1
-
44
-
-
1942422737
-
Integrating pharmacology and in vivo cancer models in preclinical and clinical drug development
-
JK Peterson PJ Houghton 2004 Integrating pharmacology and in vivo cancer models in preclinical and clinical drug development Eur J Cancer 40 837 844
-
(2004)
Eur J Cancer
, vol.40
, pp. 837-844
-
-
Peterson, J.K.1
Houghton, P.J.2
-
45
-
-
0032925417
-
The dolastatins, a family of promising antineoplastic agents
-
J Poncet 1999 The dolastatins, a family of promising antineoplastic agents Curr Pharm Des 5 139 162
-
(1999)
Curr Pharm des
, vol.5
, pp. 139-162
-
-
Poncet, J.1
-
46
-
-
4944234717
-
Low concentrations of vinflunine induce apoptosis in human SK-N-SH neuroblastoma cells through a post mitotic G1 arrest and a mitochondrial pathway
-
B Pourroy M Carre S Honore et al. 2004 Low concentrations of vinflunine induce apoptosis in human SK-N-SH neuroblastoma cells through a post mitotic G1 arrest and a mitochondrial pathway Mol Pharmacol 66 580 591
-
(2004)
Mol Pharmacol
, vol.66
, pp. 580-591
-
-
Pourroy, B.1
Carre, M.2
Honore, S.3
-
47
-
-
34248592567
-
Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate
-
A Ray T Okouneva T Manna 2007 Mechanism of action of the microtubule-targeted antimitotic depsipeptide tasidotin (formerly ILX651) and its major metabolite tasidotin C-carboxylate Cancer Res 67 3767 3776
-
(2007)
Cancer Res
, vol.67
, pp. 3767-3776
-
-
Ray, A.1
Okouneva, T.2
Manna, T.3
-
48
-
-
0026428123
-
Studies with RP56967 (Taxotere): A semisynthetic analog of taxol
-
I Ringel SB Horwitz 1991 Studies with RP56967 (Taxotere): a semisynthetic analog of taxol J Natl Cancer Inst 83 288 291
-
(1991)
J Natl Cancer Inst
, vol.83
, pp. 288-291
-
-
Ringel, I.1
Horwitz, S.B.2
-
49
-
-
0002576411
-
Antimicrotubule agents
-
Chabner BA, Longo DL (eds) Lippincott-Raven, New York
-
Rowinsky EK, Donehower RC (1996) Antimicrotubule agents. In: Chabner BA, Longo DL (eds) Cancer chemotherapy and biotherapy. Lippincott-Raven, New York, pp 263-296
-
(1996)
Cancer Chemotherapy and Biotherapy
, pp. 263-296
-
-
Rowinsky, E.K.1
Donehower, R.C.2
-
50
-
-
0019777859
-
Pharmacokinetics of vincristine sulfate in children
-
VS Sethi JC Kimball 1981 Pharmacokinetics of vincristine sulfate in children Cancer Chemother Pharmacol 6 111 115
-
(1981)
Cancer Chemother Pharmacol
, vol.6
, pp. 111-115
-
-
Sethi, V.S.1
Kimball, J.C.2
-
51
-
-
33646473687
-
Cell cycle effects of vinflunine, the most promising Vinca alkaloid and its interaction with radiation in vitro
-
C Simoens JB Vermorken AEC Korst et al. 2006 Cell cycle effects of vinflunine, the most promising Vinca alkaloid and its interaction with radiation in vitro Cancer Chemother Pharmacol 58 210 218
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 210-218
-
-
Simoens, C.1
Vermorken, J.B.2
Korst, A.E.C.3
-
52
-
-
0027270462
-
Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew
-
A Stierle G Strobel D Stierle 1993 Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew Science 260 214 218
-
(1993)
Science
, vol.260
, pp. 214-218
-
-
Stierle, A.1
Strobel, G.2
Stierle, D.3
-
53
-
-
34548385316
-
Nanoparticle albumin-bound paclitaxel: A novel cremophor-EL-free formulation of paclitaxel
-
TE Stinchcombe 2007 Nanoparticle albumin-bound paclitaxel: a novel cremophor-EL-free formulation of paclitaxel Nanomedicine 2 415 423
-
(2007)
Nanomedicine
, vol.2
, pp. 415-423
-
-
Stinchcombe, T.E.1
-
54
-
-
41549130929
-
Newer cytotoxic agents: Attacking cancer broadly
-
BA Teicher 2008 Newer cytotoxic agents: attacking cancer broadly Clin Cancer Res 14 1610 1617
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1610-1617
-
-
Teicher, B.A.1
-
55
-
-
36048976055
-
The use of taxanes in the neoadjuvant treatment of breast cancer: A review of randomized phase II/III trials
-
I Tusquets LG Estevez I Alvarez et al. 2007 The use of taxanes in the neoadjuvant treatment of breast cancer: a review of randomized phase II/III trials Clin Breast Cancer 7 764 774
-
(2007)
Clin Breast Cancer
, vol.7
, pp. 764-774
-
-
Tusquets, I.1
Estevez, L.G.2
Alvarez, I.3
-
56
-
-
0031691614
-
Preclinical pharmacology, toxicology and efficacy of sphingomyelin/ cholesterol liposomal vincristine for therapeutic treatment of cancer
-
MS Webb P Logan PM Kanter et al. 1998 Preclinical pharmacology, toxicology and efficacy of sphingomyelin/cholesterol liposomal vincristine for therapeutic treatment of cancer Cancer Chemother Pharmacol 42 461 470
-
(1998)
Cancer Chemother Pharmacol
, vol.42
, pp. 461-470
-
-
Webb, M.S.1
Logan, P.2
Kanter, P.M.3
-
57
-
-
38449086772
-
Clinical pharmacology and use of microtubule targeting agents in cancer therapy
-
AB Zelnak 2007 Clinical pharmacology and use of microtubule targeting agents in cancer therapy Methods Mol Med 137 209 234
-
(2007)
Methods Mol Med
, vol.137
, pp. 209-234
-
-
Zelnak, A.B.1
-
58
-
-
40949139337
-
Aspects of chemotherapy schedules in young and elderly patients with aggressive lymphoma
-
C Zwick B Gleissner M Pfreundschuh 2007 Aspects of chemotherapy schedules in young and elderly patients with aggressive lymphoma Clin Lymphoma Myeloma 8 suppl 2 S43 49
-
(2007)
Clin Lymphoma Myeloma
, vol.8
, Issue.SUPPL. 2
-
-
Zwick, C.1
Gleissner, B.2
Pfreundschuh, M.3
|