GRP78 as a marker of pre-eclampsia: An exploratory study

Molecular Human Reproduction

Volumn 15, Issue 9, 2009, Pages 569-574

  Laverriere A ^a   Landau, R ^b   Charvet, I ^c   Irion, O ^a   Bischof, P ^a   Morales, M ^a   Cohen, Marie ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^c GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

C terminal fragment; GP78; Marker; Pre eclampsia

Indexed keywords

AUTOANTIBODY; GLUCOSE REGULATED PROTEIN 78; GLUCOSE REGULATED PROTEIN 78 ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY BLOOD LEVEL; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE MARKER; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPLORATORY RESEARCH; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; PREECLAMPSIA; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

AUTOANTIBODIES; BIOLOGICAL MARKERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GESTATIONAL AGE; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; PRE-ECLAMPSIA; PREGNANCY; PREGNANCY TRIMESTER, FIRST;

EID: 69049093938     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gap037     Document Type: Article

References (22)

1. Bischof P, Martelli M, Campana A, Itoh Y, Ogata Y, Nagase H. Importance of matrix metalloproteinases in human trophoblast invasion. Early Pregnancy 1995;1:263-269.
2. Castelli A, Delpino M. The 78 kDa glucose-regulated protein (GRP78/BIP) is expressed on the cell membrane, is released into cell culture medium and is also present in human peripheral circulation. Biosci Rep 2002; 22:407-420.
3. Chafetz I, Kuhnreich I, Sammar M, Tal Y, Gibor Y, Meiri H, Cuckle H, Wolf M. First-trimester placental protein 13 screening for preeclampsia and intrauterine growth restriction. Am J Obstet Gynecol 2007; 197:35.e1-7.
4. Davidson DJ, Haskell C, Majest S et al. Kringle 5 of human plasminogen induces apoptosis of endothelial and tumor cells through surface-expressed glucose-regulated protein 78. Cancer Res 2005; 65:4663-4672.
5. Dong D et al. Spontaneous and controllable activation of suicide gene expression driven by the stress-inducible grp78 promoter resulting in eradication of sizable human tumors. Hum Gene Ther 2004;15 553-661.
6. Fu Y, Lee AS. Glucose regulated proteins in cancer progression, drug resistance and immunotherapy. Cancer Biol Ther 2006;5 741-744.
7. Gerretsen G, Huisjes HJ, Elema JD. Morphological changes of the spiral arteries in the placental bed in relation to pre-eclampsia and fetal growth retardation. Br J Obstet Gynaecol 1981;88:876-881.
8. Gonen R, Shahar R, Grimpel YI, Chefetz I, Sammar M, Meiri H, Gibor Y. Placental protein 13 as an early marker for pre-eclampsia: A prospective longitudinal study. BJOG 2008;115:1465-1472.
9. Huppertz B, Sammar M, Chefetz I, Neumaier-Wagner P, Bartz C, Meiri H. Longitudinal determination of serum placental protein 13 during development of preeclampsia. Fetal Diagn Ther 2008;24 230-236.
10. Lee AS. The glucose-regulated proteins: Stress induction and clinical applications. Trends Biochem Sci 2001;26:504-510.
11. Lee AS. GRP78 induction in cancer: Therapeutic and prognostic implications. Cancer Res 2007;67:3496-3499.
12. Li J, Lee AS. Stress induction of GRP78/BiP and its role in cancer. Curr Mol Med 2006;6:45-54.
13. Meisser A, Cohen M, Bischof P. Concentrations of circulating gelatinases (matrix metalloproteinase-2 and -9) are dependent on the conditions of blood collection. Clin Chem 2005;51:274-276.
14. Mintz PJ, Kin J, Do KA et al. Fingerprinting the circulating repertoire of antibodies from cancer patients. Nat Biotechnol 2003;21:57-63.
15. Myers JE, Merchant SJ, Macleod M, Mires GJ, Baker PN, Davidge ST. MMP-2 levels are elevated in the plasma of women who subsequently develop preeclampsia. Hypertens Pregnancy 2005;24:103-115.
16. Narumiya H, Zhang Y, Fernandez-Patron C, Guilbert LJ, Davidge ST. Matrix metalloproteinase-2 is elevated in the plasma of women with preeclampsia. Hypertens Pregnancy 2001;20:185-194.
17. Paltiel O, Fridlander Y, Tiram E, Barchana M, Xue S, Harlap S. Cancer after pre-eclampsia: Follow-up of the Jerusalem perinatal study cohort. BMJ 2007;328:919.
18. Pang ZJ, Xing FQ. Expression profile of trophoblast invasion-associated genes in the pre-eclamptic placenta. Br J Biomed Sci 2003;60 97-101.
19. Robertson WB, Brosens I, Dixon HG. The pathological response of the vessels of the placental bed to hypertensive pregnancy. J Pathol Bacteriol 1967;93:581-592.
20. Shin BK, Wang H, Yim AM, Le Naour F, Brichory F, Jang JH, Zhao R, Puravs E, Tra J, Michael CW, Misek DE, Hanash SM. Global profiling of the cell surface proteome of cancer cells uncovers an abundance of proteins with chaperone function. J Biol Chem 2003;278:7607-7616.
21. Terry MB, Perrin M, Salafia CM, Zhang F, Neugut AI, Teitelbaum S L, Britton J, Gammon MD. Preeclampsia, Pregnancy-related Hypertension, and Breast Cancer Risk. Am J Epidemiol 2007; 165:1007-1014.
22. Zhang J, Jiang Y, Jia Z, Li Q, Gong W, Wang L, Wei D, Yao J, Fang S, Xie K. Association of elevated GRP78 expression with increased lymph node metastasis and poor prognosis in patients with gastric cancer. Clin Exp Metastasis 2006;23:401-410.