The role of soluble components in ambient fine particles-induced changes in human lungs and blood

Inhalation Toxicology

Volumn 15, Issue 4, 2003, Pages 327-342

  Huang, Yuh Chin T ^a,c   Ghio, Andrew J ^a   Stonehuerner, Jackie ^a   McGee, John ^a   Carter, Jacqueline D ^a   Grambow, Steven C ^b   Devlin, Robert B ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; IRON; SELENIUM; SULFATE; WATER; ZINC;

ADULT; AMBIENT AIR; ARTICLE; BLOOD; BLOOD FILTRATION; BLOOD SAMPLING; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DATA ANALYSIS; EXPOSURE; FEMALE; FIBRINOGEN BLOOD LEVEL; HEMATOLOGY; HUMAN; LUNG; LUNG INFECTION; LUNG LAVAGE; MALE; NEUTROPHILIA; PARTICLE SIZE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SOLUBILITY; VENOUS BLOOD; VOLUNTEER;

ADULT; AIR POLLUTANTS; ARSENIC; BLOOD PLATELETS; BRONCHOALVEOLAR LAVAGE; COPPER; FEMALE; FERRITINS; FIBRINOGEN; FIBRONECTINS; HUMANS; IRON; LEAD; LUNG DISEASES; MALE; NEUTROPHILS; NICKEL; NORTH CAROLINA; PARTICLE SIZE; SELENIUM; SULFATES; VANADIUM; ZINC;

EID: 0037394919     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/08958370304460     Document Type: Article

References (53)

1. Abbey, D. E., Ostro, B. E., Petersen, F., and Burchette, R. J. 1995. Chronic respiratory symptoms associated with estimated long-term ambient concentrations of fine particulates less than 2.5 microns in aerodynamic diameter (PM2.5) and other air pollutants. J. Expos. Anal. Environ. Epidemiol. 5:137-159.
2. Adamson, I. Y., Prieditis, H., Hedgecock, C., and Vincent, R. 2000. Zinc is the toxic factor in the lung response to an atmospheric particulate sample. Toxicol. Appl. Pharmacol. 166:111-119.
3. Borja-Aburto, V. H., Castillejos, M., Gold, D. R., Bierzwinski, S., and Loomis, D. 1998. Mortality and ambient fine particles in southwest Mexico City, 1993-1995. Environ. Health Perspect. 106:849-855.
4. Carter, J. D., Ghio, A. J., Samet, J. M., and Devlin, R. B. 1997. Cytokine production by human airway epithelial cells after exposure to an air pollution particle is metal-dependent. Toxicol. Appl. Pharmacol. 146:180-188.
5. Clarke, R. W., Catalano, P. J., Koutrakis, P., Murthy, G. G., Sioutas, C., Paulauskis, J., Coull, B., Ferguson, S., and Godleski, J. J. 1999. Urban air particulate inhalation alters pulmonary function and induces pulmonary inflammation in a rodent model of chronic bronchitis. Inhal. Toxicol. 11: 637-656.
6. Clarke, R. W., Coull, B., Reinisch, U., Catalano, P., Killingsworth, C. R., Koutrakis, P., Kavouras, I., Murthy, G. G., Lawrence, J., Lovett, E., Wolfson, J. M., Verrier, R. L., and Godleski, J. J. 2000. Inhaled concentrated ambient particles are associated with hematologic and bronchoalveolar lavage changes in canines. Environ. Health Perspect. 108:1179-1187.
7. Costa, D. L., and Dreher, K. L. 1997. Bioavailable transition metals in particulate matter mediate cardiopulmonary injury in healthy and compromised animal models. Environ. Health Perspect. 105 (suppl. 5):1053-1060.
8. Dockery, D. W., and Pope, C. A. 3rd. 1994. Acute respiratory effects of particulate air pollution. Annu. Rev. Public Health 15:107-132.
9. Dockery, D. W., Speizer, F. E., Stram, D. O., Ware, J. H., Spengler, J. D., and Ferris, B. G., Jr. 1989. Effects of inhalable particles on respiratory health of children. Am. Rev. Respir. Dis. 139:587-594.
10. Dockery, D. W., Schwartz, J., and Spengler, J. D. 1992. Air pollution and daily mortality: Associations with particulates and acid aerosols. Environ. Res. 59:362-373.
11. Dockery, D. W., Pope, A. C. D., Xu, X., Spengler, J. D., Ware, J. H., Fay, M. E., Ferris, B. G., Jr., and Speizer, F. E. 1993. An association between air pollution and mortality in six U.S. cities [see comments]. N. Engl. J. Med. 329:1753-1759.
12. Dreher, K. L., Jaskot, R. H., Lehmann, J. R., Richards, J. H., McGee, J. K., Ghio, A. J., and Costa, D. L. 1997. Soluble transition metals mediate residual oil fly ash induced acute lung injury. J. Toxicol. Environ. Health 50:285-305.
13. Dye, J. A., Adler, K. B., Richards, J. H., and Dreher, K. L. 1999. Role of soluble metals in oil fly ash-induced airway epithelial injury and cytokine gene expression. Am. J. Physiol. 277:L498-510.
14. Frampton, M. W., Ghio, A. J., Samet, J. M., Carson, J. L., Carter, J. D., and Devlin, R. B. 1999. Effects of aqueous extracts of PM(10) filters from the Utah valley on human airway epithelial cells. Am. J. Physiol. 277:L960-967.
15. Gardner, S. Y., Lehmann, J. R., and Costa, D. L. 2000. Oil fly ash-induced elevation of plasma fibrinogen levels in rats. Toxicol. Sci. 56:175-180.
16. Gavett, S. H., Madison, S. L., Dreher, K. L., Winsett, D. W., McGee, J. K., and Costa, D. L. 1997. Metal and sulfate composition of residual oil fly ash determines airway hyperreactivity and lung injury in rats. Environ. Res. 72:162-172.
17. Ghio, A, J., and Devlin, R. B. 2001. Inflammatory lung injury after bronchial instillation of air pollution particles. Am. J. Respir. Crit. Care Med. 164:704-708.
18. Ghio, A. J., Stoneheurner, J., Pritchard, R. J., Piantadosi, C. A., Quigley, D. R., Dreher, K. L., and Costa, D. L. 1996. Humic-like substances in air pollution particulates correlate with concentrations of transition metals and oxidant generation. Inhal. Toxicol. 8:479-494.
19. Ghio, A. J., Stonehuerner, J., Dailey, L. A., and Carter, J. D. 1999. Metals associated with both the water-soluble and insoluble fractions of an ambient air pollution particle catalyze an oxidative stress. Inhal. Toxicol. 11:37-49.
20. Ghio, A. J., Kim, C., and Devlin, R. B. 2000. Concentrated ambient air particles induce mild pulmonary inflammation in healthy human volunteers. Am. J. Respir. Crit. Care Med. 162:981-988.
21. Godleski, J. J., Verrier, R. L., Koutrakis, P., and Catalano, P. 2000a. Mechanisms of morbidity and mortality from exposure to ambient air particles. Rep. no. 91. Cambridge, MA: Health Effects Institute.
22. Godleski, J. J., Verrier, R. L., Koutrakis, P., Catalano, P., Coull, B., Reinisch, U., Lovett, E. G., Lawrence, J., Murthy, G. G., Wolfson, J. M., Clarke, R. W., Nearing, B. D., and Killingsworth, C. 2000b. Mechanisms of morbidity and mortality from exposure to ambient air particles. Res. Rep. Health Effects Inst. 5-88; discussion 89-103.
23. Kannel, W. B. 2000. The Framingham Study: ITS 50-year legacy and future promise. J. Atheroscler. Thromb. 6:60-66.
24. Kennedy, T., Ghio, A. J., Reed, W., Samet, J., Zagorski, J., Quay, J., Carter, J., Dailey, L., Hoidal, J. R., and Devlin, R. B. 1998. Copper-dependent inflammation and nuclear factor-kappaB activation by particulate air pollution. Am. J. Respir. Cell Mol. Biol. 19:366-378.
25. Kodavanti, U. P., Hauser, R., Christiani, D. C., Meng, Z. H., McGee, J., Ledbetter, A., Richards, J., and Costa, D. L. 1998. Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals. Toxicol. Sci. 43:204-212.
26. Kullo, I. J., Gau, G. T., and Tajik, A. J. 2000. Novel risk factors for atherosclerosis. Mayo Clin. Proc. 75 (4):369-380.
27. Laden, F., Neas, L. M., Dockery, D. W., and Schwartz, J. 2000. Association of fine particulate matter from different sources with daily mortality in six U.S. cities. Environ. Health Perspect. 108:941-947.
28. Lindahl, B., Toss, H., Siegbahn, A., Venge, P., and Wallentin, L. 2000. Markers of myocardial damage and inflammation in relation to long-term mortality in unstable coronary artery disease. N. Engl. J. Med. 343:1139-1147.
29. Maharshak, N., Kassirer, M., Zeltser, D., Rotstein, R., Rogowski, O., Shapira, I., Deutsch, V., Arber, N., Eldor, A., and Berliner, S. 2000. The inflammation meter: novel technology to detect the presence of infection/inflammation in patients without leukocytosis but with increased leukocyte adhesiveness/aggregation. Acta Haematol. 104(1):16-21.
30. Marks, P. W., Hendey, B., and Maxfield, F. R. 1991. Attachment to fibronectin or vitronectin makes human neutrophil migration sensitive to alterations in cytosolic free calcium concentration. J. Cell Biol. 112:149-158.
31. Michelozzi, P., Forastiere, F., Fusco, D., Perucci, C. A., Ostro, B., Ancona, C., and Pallotti, G. 1998. Air pollution and daily mortality in Rome, Italy. Occup. Environ. Med. 55:605-610.
32. Olivares, J. A. 1988. Inductively coupled plasma-mass spectrometry. Methods Enzymol. 158:205-222.
33. Ostro, B. 1995. Fine particulate air pollution and mortality in two Southern California counties. Environ. Res. 70:98-104.
34. Packard, C. J., O'Reilly, D. S. J., Caslake, M. J., McMahon, A. D., Ford, I., Cooney, J., Macphee, C. H., Suckling, K. E., Krishna, M., Wilkinson, F. E., Rumley, A., and Lowe, G. D. 2000. Lipoprotein-associated phospholipase A(2) as an independent predictor of coronary heart disease. N. Engl. J. Med. 343:1148-1155.
35. Parekh, T., Saxena, B., Reibman, J., Cronstein, B. N., and Gold, L. I. 1994. Neutrophil chemotaxis in response to TGF-beta isoforms (TGF-beta 1, TGF-beta 2, TGF-beta 3) is mediated by fibronectin. J. Immunol. 152:2456-2466.
36. Pekkanen, J., Brunner, E. J., Anderson, H. R., Tiittanen, P., and Atkinson, R. W. 2000. Daily concentrations of air pollution and plasma fibrinogen in London. Occup. Environ. Med. 57:818-822.
37. Peters, A., Liu, E., Verrier, R. L., Schwartz, J., Gold, D. R., Mittleman, M., Baliff, J., Oh, J. A., Allen, G., Monahan, K., and Dockery, D. W. 2000. Air pollution and incidence of cardiac arrhythmia [see comments]. Epidemiology 11:11-17.
38. Peters, A., Dockery, D. W., Muller, J. E., and Mittleman, M. A. 2001. Increased particulate air pollution and the triggering of myocardial infarction. Circulation 103:2810-2815.
39. Ponka, A., and Virtanen, M. 1996. Low-level air pollution and hospital admissions for cardiac and cerebrovascular diseases in Helsinki. Am. J. Public Health 86:1273-1280.
40. Pope, C. A. 3rd, Thun, M. J., Namboodiri, M. M., Dockery, D. W., Evans, J. S., Speizer, F. E., and Heath, C. W.,Jr. 1995. Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults. Am. J. Respir. Crit. Care Med. 151:669-674.
41. Pope, C. A. 3rd, Verrier, R. L., Lovett, E. G., Larson, A. C., Raizenne, M. E., Kanner, R. E., Schwartz, J., Villegas, G. M., Gold, D. R., and Dockery, D. W. 1999. Heart rate variability associated with particulate air pollution. Am. Heart J. 138:890-899.
42. Pradella, M., Nemetz, L., Bovo, C., Visentin, M., Clemen, P., Zappala, G., Ossani, M., and Plebani, M. 1995. Quantitative cytochemistry of human leukocyte elastase compared with plasma elastase and acute phase proteins in inflammatory diseases. Clin. Chim. Acta 239(1):91-101.
43. Prahalad, A. K., Inmon, J., Dailey, L. A., Madden, M. C., Ghio, A. J., and Gallagher, J. E. 2001. Air pollution particles mediated oxidative DNA base damage in a cell free system and in human airway epithelial cells in relation to particulate metal content and bioreactivity. Chem. Res. Toxicol. 14: 879-887.
44. Pritchard, R. J., Ghio, A. J., Lehmann, J. R., Winsett, D. W., Tepper, J. S., Park, P., Gilmour, M. I., Dreher, K. L., and Costa, D. L. 1996. Oxidant generation and lung injury after particulate air pollution exposure increase with the concentrations of associated metals. Inhal. Toxicol. 8:457-477.
45. Salvi, S., Blomberg, A., Rudell, B., Kelly, F., Sandstrom, T., Holgate, S. T., and Frew, A. 1999. Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am. J. Respir. Crit. Care Med. 159:702-709.
46. Samet, J. M., Dominici, F., Curriero, F. C., Coursac, I., and Zeger, S. L. 2000a. Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N. Engl. J. Med. 343:1742-1749.
47. Samet, J. M., Zeger, S. L., Dominici, F., Curriero, F., Coursac, I., Dockery, D. W., Schwartz, J., and Zanobetti, A. 2000b. The National Morbidity, Mortality, and Air Pollution Study. Part II: Morbidity and mortality from air pollution in the United States. Res. Rep. Health Effects Inst. 94:5-70; discussion 71-79.
48. Schwartz, J. 1999. Air pollution and hospital admissions for heart disease in eight U.S. counties. Epidemiology 10:17-22.
49. Schwartz, J., Dockery, D. W., and Neas, L. M. 1996. Is daily mortality associated specifically with fine particles? J. Air Waste Manage. Assoc. 46:927-939.
50. Thurston, G. D., Ito, K., Hayes, C. G., Bates, D. V., and Lippmann, M. 1994. Respiratory hospital admissions and summertime haze air pollution in Toronto, Ontario: Consideration of the role of acid aerosols. Environ. Res. 65:271-290.
51. U.N. Environmental Programme and WHO Report. 1994. Air pollution in the world's megacities: A report from the U.N. Environmental Programme and WHO. Environment 36:5-37.
52. U.S. Environmental Protection Agency. 1995. Air quality criteria for particulate matter. Vol. III, EPA-600/P-95/001aF. Research Triangle Park, NC: U.S. Environmental Protection Agency, Environmental Criteria and Assessment Office.
53. Winchester, J. W. 1990. Soluble metals in the atmosphere and their biological implications. In Biological trace element research, ed. G. N. Schrauzer, pp. 195-212. Totowa, NJ: Humana Press.