A novel SCN5A mutation V1340I in Brugada syndrome augmenting arrhythmias during febrile illness

Heart Rhythm

Volumn 6, Issue 9, 2009, Pages 1318-1326

  Samani, Kaveh ^a   Wu, Geru ^a   Ai, Tomohiko ^a,b   Shuraih, Mossaab ^a   Mathuria, Nilesh S ^a   Li, Zhaohui ^c   Sohma, Yoshiro ^d,e   Purevjav, Enkhsaikhan ^c   Xi, Yutao ^a   Towbin, Jeffrey A ^c   Cheng, Jie ^a   Vatta, Matteo ^c  

^a ST LUKE S EPISCOPAL HOSPITAL   (United States)

^b OSAKA MEDICAL COLLEGE   (Japan)

^c TEXAS CHILDREN S HOSPITAL   (United States)

^d KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e UNIVERSITY OF MISSOURI   (United States)

Author keywords

Arrhythmia; Brugada syndrome; Mutation; Severe; Sodium channel

Indexed keywords

SCN5A PROTEIN; UNCLASSIFIED DRUG; VOLTAGE GATED SODIUM CHANNEL; MUSCLE PROTEIN; SCN5A PROTEIN, HUMAN; SODIUM CHANNEL; SODIUM CHANNEL NAV1.5;

ADULT; ARTICLE; BLOOD SAMPLING; BRUGADA SYNDROME; CARDIAC PATIENT; CASE REPORT; CELL MEMBRANE; CELL STRAIN HEK293; CONTROLLED STUDY; DEFIBRILLATOR; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DNA MODIFICATION; ELECTROCARDIOGRAM; EMBRYO; FEVER; GENE ACTIVATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE INACTIVATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LOSS OF FUNCTION MUTATION; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PATCH CLAMP; PATHOGENESIS; POLYMORPHIC VENTRICULAR TACHYCARDIA; PRIORITY JOURNAL; SODIUM CURRENT; STEADY STATE; SYNCOPE; TEMPERATURE; WILD TYPE; ARRHYTHMIAS, CARDIAC; DISEASE COURSE; GENETICS; JAPAN; PATHOLOGY; TACHYCARDIA, VENTRICULAR;

ADULT; ARRHYTHMIAS, CARDIAC; BRUGADA SYNDROME; DISEASE PROGRESSION; FEVER; HUMANS; JAPAN; MALE; MUSCLE PROTEINS; MUTATION, MISSENSE; SODIUM CHANNELS; TACHYCARDIA, VENTRICULAR; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL;

EID: 68949219422     PISSN: 15475271     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hrthm.2009.05.016     Document Type: Article

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