Establishment and characterization of pleomorphic adenoma cell systems: An in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland

BMC Cancer

Volumn 9, Issue , 2009, Pages

  Maruyama, Satoshi ^a,b   Cheng, Jun ^a   Shingaki, Susumu ^a   Tamura, Takashi ^c   Asakawa, Shuichi ^d   Minoshima, Shinsei ^e   Shimizu, Yoshiko ^c   Shimizu, Nobuyoshi ^f   Saku, Takashi ^a,b  

^a NIIGATA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY MEDICAL AND DENTAL HOSPITAL   (Japan)

^c KYORIN UNIVERSITY   (Japan)

^d KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^f KEIO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

KERATIN; PROTEIN P53; PROTEIN S 100;

ADULT; ANIMAL CELL; ARTICLE; BENIGN TUMOR; CELL CLONE; CELL DIFFERENTIATION; CELL SHAPE; CELL TRANSFORMATION; CHROMOSOME 13Q; CHROMOSOME 9P; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CHROMOSOME TRANSLOCATION 13; CHROMOSOME TRANSLOCATION 9; CODON; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HETEROZYGOSITY LOSS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALIGNANT TRANSFORMATION; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PAROTID GLAND ADENOMA; PAROTID GLAND TUMOR; PLEOMORPHIC ADENOMA; POINT MUTATION; SALIVARY GLAND CARCINOMA; SPINDLE CELL; SQUAMOUS CELL CARCINOMA; STRUCTURAL CHROMOSOME ABERRATION; TUMOR CELL CULTURE; TUMOR XENOGRAFT; ADENOMA; ANIMAL; BACTERIAL ARTIFICIAL CHROMOSOME; CANCER TRANSPLANTATION; CARCINOMA; CASE REPORT; FLUORESCENCE MICROSCOPY; METABOLISM; METASTASIS; METHODOLOGY; MIDDLE AGED; PATHOLOGY; SALIVARY GLAND TUMOR; TUMOR SUPPRESSOR GENE;

ADENOMA; ANIMALS; CARCINOMA; CHROMOSOMES, ARTIFICIAL, BACTERIAL; DNA MUTATIONAL ANALYSIS; FEMALE; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION, FLUORESCENCE; MICE; MICE, NUDE; MICROSCOPY, FLUORESCENCE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; SALIVARY GLAND NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 68949198928     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-9-247     Document Type: Article

References (40)

1. Gnepp DR Wening BM Malignant mixed tumors Surgical pathology of the Salivary Glands Philadelphia: W.B. Saunders Ellis GL, Auclair PL, Gnepp DR 1991, 350-368.
2. Ellis GL Auclair PL Tumor of the Salivary Glands: Atlas of Tumor Pathology, 3rd Series Washington, DC: Armed Forces Institute of Pathology 1996, 228-238.
3. Ohtaké S Cheng J Ida H Suzuki M Ohshiro K Zhang W Saku T Precancerous foci in pleomorphic adenoma of the salivary gland: recognition of focal carcinoma and atypical tumor cells by P53 immunohistochemistry J Oral Pathol Med 2002, 31:590-597. 10.1034/ j.1600-0714.2002.00040.x 12406304
4. Brandwein M Huvos AG Dardick I Thomas MJ Theise ND Noninvasive and minimally invasive carcinoma ex mixed tumor: A clinicopathologic and ploidy study of 12 patients with major salivary tumors of low (or no?) malignant potential Oral Surg Oral Med Oral Pathol Radiol Endod 1996, 81:655-664. 10.1016/S1079-2104(96)80071-0
5. Auclair PL Ellis GL Atypical features in salivary gland mixed tumors: their relationship to malignant transformation Mod Pathol 1996, 9:652-657. 8782203
6. Takeda Y An immunohistochemical study of bizarre neoplastic cells in pleomorphic adenoma: Its cytological nature and proliferative activity Pathol Int 1999, 49:993-999. 10.1046/j.1440-1827.1999.00968.x 10594846
7. Kas K Voz ML Roijer E Astrom AK Meyen E Stenman G Ven Van de WJ Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleomorphic adenomas with t(3;8)(p21;q12) translocations Nat Genet 1997, 15:170-174. 10.1038/ng0297-170 9020842
8. Astrom AK Voz ML Kas K Roijer E Wedell B Mandahl N Ven W Mark J Stenman G Conserved mechanism of PLAG1 activation in salivary gland tumors with and without chromosome 8q12 abnormalities: Identification of SII as a new fusion partner gene Cancer Res 1999, 59:918-923. 10029085
9. Voz ML Astrom AK Kas K Mark J Stenman G Ven Van de WJ The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas result in upregulation of PLAG1 gene expression under control of the LIFR promoter Oncogene 1998, 16:1409-1416. 10.1038/sj.onc.1201660 9525740
10. Deguchi H Hamano H Hayashi Y c-myc, ras p21 and p53 expression in pleomorphic adenoma and its malignant form of the human salivary glands Acta Pathol Jpn 1993, 43:413-422. 8396843
11. Yamamoto Y Kishimoto Y Wistuba II Virmani AK Vuitch F Gazder AF Albores-Saavedra J DNA analysis at p53 locus in carcinomas arising from pleomorphic adenomas of salivary glands: Comparison of molecular study and p53 immunostaining Pathol Int 1998, 48:265-272. 10.1111/ j.1440-1827.1998.tb03904.x 9648154
12. Righi PD Li YQ Deutsch M Mcdonald JS Wilson KM Bejarano P Stambrook PJ Osterhage D Nguyen C Gluckman JL Pavelic ZP The role of the p53 gene in the malignant transformation of pleomorphic adenomas of the parotid gland Anticancer Res 1994, 14:2253-2258. 7840532
13. Fujioka M Shimada K Kitazawa S Maeda S Molecular characterization of a novel cancer cell line established from human carcinoma in pleomorphic adenoma (caPA-4) Int J Cancer 1996, 67:204-210. 10.1002/ (SICI)1097-0215(19960717)67:2<204::AID-IJC10>3.0.CO;2-B 8760589
14. Weber A Langhanki L Schutz A Gerstner A Bootz F Wittekind C Tannapfel A Expression profiles of p53, p63, and p73 in benign salivary gland tumors Virchows Arch 2002, 441:428-436. 10.1007/s00428-002-0705-y 12447671
15. Lewis JE Olsen KD Sebo TJ Carcinoma ex pleomorphic adenoma: Pathologic analysis of 73 cases Human Pathol 2001, 32:596-604. 10.1053/ hupa.2001.25000
16. Karja VJ Syrjanen KJ Kurvinen AK Syrjanen SM Expression and mutations of p53 in salivary gland tumors J Oral Pathol Med 1997, 26:217-223. 10.1111/ j.1600-0714.1997.tb01227.x 9178173
17. Li X Tsuji T Wen S Mimura Y Sasaki K Shinozaki F Detection of numeric abnormalities of chromosome 17 and p53 deletions by fluorescence in situ hybridization in pleomorphic adenomas and carcinomas in pleomorphic adenoma Cancer 1997, 79:2314-2319. 10.1002/ (SICI)1097-0142(19970615)79:12<2314::AID-CNCR4>3.0.CO;2-L 9191518
18. Weber A Langhanki L Schutz A Wittekind C Bootz F Tannapfel A Alterations of the INK4a-ARF gene locus in pleomorphic adenoma of the parotid gland J Pathol 2002, 198:326-334. 10.1002/path.1210 12375265
19. Kondo T Muragishi H Imaizumi M A cell line from a human salivary gland mixed tumor Cancer 1971, 27:403-410. 10.1002/ 1097-0142(197102)27:2<403::AID-CNCR2820270225>3.0.CO;2-B 5100402
20. Jaeger MM Araujo VC Kachar B Jaeger RG Effect of spatial arrangement of the basement membrane on cultured pleomorphic adenoma cells. Study by immunocytochemistry and electron and conforcal microscopy Virchows Arch 1997, 430:467-477. 10.1007/s004280050057 9230912
21. Shirasuna K Sato M Miyazaki T A myoepithelial cell line established from a human pleomorphic adenoma arising in minor salivary gland Cancer 1980, 45:297-305. 10.1002/ 1097-0142(19800115)45:2<297::AID-CNCR2820450217>3.0.CO;2-R 6243244
22. Bullerdiek J Hutter KJ Brandt G Weinberg M Belge G Bartnitzke S Cytogenetic investigations on a cell line derived from a carcinoma arising in a salivary gland pleomorphic adenoma Cancer Genet Cytogenet 1990, 44:253-262. 10.1016/0165-4608(90)90054-E 2153441
23. Rohen C Rogalla P Meyer-Bolte K Bartnitzke S Chila R Bullerdiek J Pleomorphic adenomas of the salivary glands: Absence of HMGIY rearrangements Cancer Genet Cytogenet 1999, 111:178-181. 10.1016/ S0165-4608(98)00241-6 10347561
24. Mark J Dahlenfors R Ekedahl C Chromosomal Deviations and their specificity in human mixed salivary gland tumors Anticancer Res 1981, 1:49-57.
25. Bullerdiek J Wobst G Meyer-Bolte K Chilla R Haubrich J Thoode B Bartnitzke S Cytogenetic subtyping of 220 salivary gland pleomorphic adenomtas: Correlation to occurrence, histological subtype, and in vitro cellular behavior Cancer Genet Cytogenet 1993, 65:27-31. 10.1016/ 0165-4608(93)90054-P 8381711
26. Mark J Dahlenfors R Wedell B Impact of the in vitro technique used on the cytogenetic patterns in pleomorphic adenomas Cancer Genet Cytogenet 1997, 95:9-15. 10.1016/S0165-4608(96)00204-X 9140448
27. Johns MM Westra WH Califano JA Eisele D Koch WM Sidransky D Allelotype of salivary gland tumors Cancer Res 1996, 56:1151-1154. 8640776
28. MacDougall M Thiemann F Ta H Hsu P Chen LS Snead ML Temperature sensitive simian virus 40 large T antigen immortalization of murine odontoblast cell cultures: Establishment of clonal odontoblast cell line Connect Tissue Res 1995, 33:97-103. 10.3109/03008209509016988 7554969
29. Cheng J Irié T Munakata R Kimura S Nakamura H He RG Liu AR Saku T Biosynthesis of basement membrane molecules by salivary adenoid cystic carcinoma cells: An immunofluorescence and confocal microscopic study Virchows Arch 1995, 426:577-586. 10.1007/BF00192112 7655738
30. Asakawa S Abe I Kudoh Y Kishi N Wang Y Kubota R Kudoh J Kawasaki K Minoshima S Shimizu N Human BAC library: Construction and rapid screening Gene 1997, 191:69-79. 10.1016/S0378-1119(97)00044-9 9210591
31. Devlin J Keen AJ Knowles MA Homozygous deletion mapping at 9p21 in bladder carcinoma defines a critical region within 2cM of IFNA Oncogene 1994, 9:2757-2760. 8058343
32. Cannon ALA Goldgar DE Meyer LJ Lewis CM Anderson DE Fountain JW Hegi ME Wiseman RW Patty EM Bala AE Olopade OI Diaz MO Kwiatkowski DJ Piepkorn M Zone JJ Skolnick MH Assignment of a locus for familial melanoma, MLM, to chromosome 9p13-p22 Science 1992, 258:1148-1152. 10.1126/science.1439824 1439824
33. Suzuki H Fujioka Y Deletion of p16 gene and microsatellite instability in carcinoma arising in pleomorphic adenoma of the parotid gland Diagnostic Mol Pathol 1998, 7:224-231. 10.1097/00019606-199808000-00007
34. Wathelet MG Szpirer J Mols CB Clauss IM De Wit L Islam MQ Levan G Horisberger MA Content J Szpirer C Cloning and chromosomal location of human genes inducible by type I interferon Somat Cell Mol Genet 1988, 14:415-426. 10.1007/BF01534709 3175763
35. Nakanishi H Wang XL Imai FL Kato J Shiiba M Miya T Imai Y Tanzawa H Localization of a novel tumor supressor gene loci on chromosome 9p21-22 in oral cancer Anticancer Res 1999, 19:29-34. 10226521
36. van der Riet P Nawroz H Hruban RH Corio R Tokino k Koch W Sidransky D Frequent loss of chromosome 9p21-22 early in head and neck cancer progression Cancer Res 1994, 54:1156-1158. 8118798
37. Ishwad CS Ferrell RE Rossie KN Appel BN Johnson JT Myers EN Law JC Srivastava S Gollin SM Loss of heterozygosity of the short arm of chromosomes 3 and 9 in oral cancer Int J Cancer 1996, 69:1-4. 10.1002/ (SICI)1097-0215(19960220)69:1<1::AID-IJC1>3.0.CO;2-8 8600052
38. Roijer E Nordkvist A Strom AK Ryd W Behrendt M Bullerdiek J Mark J Stenman G Translocation, deletion/amplification, and expression of HMGIC and MDM2 in a carcinoma ex pleomorphic adenoma Am J Pathol 2002, 160:433-440. 1850659 11839563
39. El-Naggar AK Callender D Coombes MM Hurr K Luna MA Batsakis JG Molecular genetic alterations in carcinoma ex pleomorphic adenoma: A putative progression model? Genes Chromosomes Cancer 2000, 27:162-168. 10.1002/ (SICI)1098-2264(200002)27:2<162::AID-GCC7>3.0.CO;2-9 10612804
40. Stephen CW Helmine P Lane DP Characterisation of epitopes on human p53 using phage-displayed peptide libraries: Insights into antibody-peptide interactions J Mol Biol 1995, 248:58-78. 10.1006/jmbi.1995.0202 7537340