Pleomorphic adenomas of the salivary glands: Absence of HMGIY rearrangements

Cancer Genetics and Cytogenetics

Volumn 111, Issue 2, 1999, Pages 178-181

  Rohen, Corina ^a   Rogalla, Piere ^a   Meyer Bolte, Kerstin ^a   Bartnitzke, Sabine ^a   Chilla, Reinhard ^b   Bullerdiek, Jörn ^a  

^a UNIVERSITY OF BREMEN   (Germany)

^b Clinic for Oto Rhino Laryngology   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH MOBILITY GROUP PROTEIN;

ARTICLE; CHROMOSOME 12Q; CHROMOSOME 6P; CHROMOSOME REARRANGEMENT; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; KARYOTYPE; MAJOR CLINICAL STUDY; PLEOMORPHIC ADENOMA; PRIORITY JOURNAL; SALIVARY GLAND TUMOR; TISSUE SPECIFICITY;

ADENOMA, PLEOMORPHIC; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 6; GENE REARRANGEMENT; HIGH MOBILITY GROUP PROTEINS; HMGA1A PROTEIN; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; NEOPLASM PROTEINS; SALIVARY GLAND NEOPLASMS; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 0032925448     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-4608(98)00241-6     Document Type: Article

References (25)

1. Mandahl N., Heim S., Johansson B., Bennet K., Mertens F., Olsson G., Roeser B., Rydholm A., Willén H., Mitelman F. Lipomas have characteristic structural chromosomal rearrangements of 12q13-q14. Int J Cancer. 39:1987;685-688.
2. Ashar H.R., Schoenberg-Feyzo M., Tkachenko A., Zhou X., Fletcher J.A., Weremowicz S., Morton C.C., Chada K. Disruption of the architectural factor HMGI-C. DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains Cell. 82:1995;57-65.
3. Dal Cin P., Kools P., De Jonge I., Moerman P.H., Van de Ven W.J.M., Van den Berghe H. Rearrangements of 12q14-15 in pulmonary chondroid hamartoma. Genes Chromosom Cancer. 8:1993;131-133.
4. Kazmierczak B., Wanschura S., Rosigkeit J., Meyer-Bolte K., Uschinsky K., Haupt R., Schoenmakers E.F.P.M., Bartnitzke S., Van de Ven W.J.M., Bullerdiek J. Molecular characterization of 12q15-15 rearrangements in three pulmonary chondroid hamartomas. Cancer Res. 5:1995;2497-2499.
5. Vanni R., Dal Cin P., Marras S., Moerman P., Andria M., Valdes E., Deprest J., Van den Berghe H. Endometrial polyp. another benign tumor characterized by 12q13-15 changes Cancer Genet Cytogenet. 68:1993;32-33.
6. Bol S., Wanschura S., Thode B., Deichert U., Van de Ven W.J.M., Bartnitzke S., Bullerdiek J. An endometrial polyp with a rearrangement of HMGI-C underlying a complex cytogenetic rearrangement involving chromosomes 2 and 12. Cancer Genet Cytogenet. 90:1996;88-90.
7. Heim S., Nilbert M., Vanni R., Floderus U.-M., Mandahl N., Lecca U., Mitelman F. A specific translocation, t(12;14)(q13-15;q13-24), characterizes a subgroup of uterine leiomyomas. Cancer Genet Cytogenet. 32:1988;13-17.
8. Hennig Y., Wanschura S., Deichert U., Bartnitzke S., Bullerdiek J. Rearrangement of the high mobility group protein family genes and the molecular origin of uterine leiomyomas and endometrial polyps. Molecular Human Reproduction. 2:1996;277-283.
9. Mark J., Dahlenfors R., Ekedahl C., Stenman G. The mixed salivary gland tumor. a normally benign human neoplasm frequently showing specific chromosomal abnormalities Cancer Genet Cytogenet. 2:1980;231-241.
10. Bullerdiek J., Wobst G., Meyer-Bolte K., Chilla R., Haubrich J., Thode B., Bartnitzke S. Cytogenetic subtyping of 220 salivary gland pleomorphic adenomas. correlation to occurrence, histological subtype, and in vitro cellular behavior Cancer Genet Cytogenet. 65:1993;27-31.
11. Schoenmakers E.F.P.M., Wanschura S., Mols R., Bullerdiek J., Van den Berghe H., Van den Ven W.J.M. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumors. Nature Genet. 10:1995;436-444.
12. Friedmann M., Holth L.T., Zoghbi H.Y., Reeves R. Organization, inducible expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene. Nucleic Acid Res. 18:1993;4259-4267.
13. Mandahl N. Lipoma cytogenetics. Bullerdiek J., Bartnitzke S. Chromosome 12 Aberrations in Human Solid Tumors. 1994;26-38 Springer, Berlin.
14. Mark J., Havel G., Grepp C., Dahlenfors R., Wedell B. Cytogenetical observations in human benign uterine leiomyomas. Anticancer Res. 8:1988;621-626.
15. Fletcher J.A., Longtine J., Wallace K., Mentzer S.J., Sugarbaker D.J. Cytogenetic and histologic findings in 17 pulmonary chondroid hamartomas. evidence for a pathogenetic relationship with lipomas and leiomyomas Genes Chromosom Cancer. 12:1995;220-223.
16. Kazmierczak B., Bol S., Wanschura S., Bartnitzke S., Bullerdiek J. PAC clone containing the HMGI(Y) gene spans the breakpoint of a 6p21 translocation in a uterine leiomyoma cell line. Genes Chromosom Cancer. 17:1996;191-193.
17. Kazmierczak B., Wanschura S., Rommel B., Bartnitzke S., Bullerdiek J. Ten pulmonary chondroid hamartomas with chromosome 6p21 breakpoints within the HMG-I(Y) gene or its immediate surroundings. J Natl Cancer Inst. 88:1996;1234-1236.
18. Williams A.J., Powell W.L., Collins T., Morton C.C. HMGI(Y) expression in human uterine leiomyomata. Am J Pathol. 150:1997;911-918.
19. Xiao S., Lux M.L., Reeves R., Hudson T.J., Fletcher J.A. HMGI(Y) activation by chromosome 6p21 rearrangements in multilineage mesenchymal cells from pulmonary hamartoma. Am J Pathol. 150:1997;901-910.
20. Tkachenko A., Ashar H.R., Meloni A.M., Sandberg A.A., Chada K.K. Misexpression of disrupted HMGI architectural factors activates alternative pathways of tumorigenesis. Cancer Res. 57:1997;2276-2280.
21. Mark J., Dahlenfors R. Cytogenetical observations in 100 human benign pleomorphic adenomas. specificity of the chromosomal aberrations and their relationship to sites of localized oncogenes Anticancer Res. 6:1986;299-308.
22. Mark J., Sandros J., Wedell B., Stenman G., Ekedahl C. Significance of the choice of tissue culture technique on the chromosomal patterns in human mixed salivary gland tumors. Cancer Genet Cytogenet. 33:1988;229-244.
23. Kazmierczak B., Dal Cin P., Wanschura S., Borrmann L., Fusco A., Van den Berghe H., Bullerdiek J. HMGIY is the target of 6p21.3 rearrangements in various mesenchymal tumors. Genes Chromosom Cancer. 23:1998;279-285.
24. Kas K., Voz M.L., Röijer E., Åström E., Meyen E., Stenman G., Van de Ven W.J.M. Promoter swapping between the genes for a novel zinc finger protein and β-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations. Nature Genet. 15:1997;170-174.
25. Ellis GL, Auclair PL (1996): Tumors of the salivary glands. Armed Forces Institute of Pathology, Washington, D.C.